Winter newsletter from the Research & Development Department at Broomfield Hospital

1. New Starters & Leavers in R&D
Dane Goodere-Bennett
Primary Care Research Facilitator
Not an unfamiliar face to the Trust having previously worked on the hospital staff bank.
Dane joined us on 3rd
January 2018 and will be supporting the Primary Care Research
Team (based in Epping) in enabling GP practice based research.
Liz Weight
Primary Care Research Nurse
After 12 months of working out of our Epping office, Liz left her role in December to
take up a position as an Occupational Health Nurse. Thank you for all your hard work Liz
and we all wish you the very best for the future.
Welcome to the Fifth Edition of ‘RESEARCH Focus’
Welcome to the fifth edition of our departmental newsletter. The last 3 months have proven to be a phenomenal end to an already
excellent 2017 for research in the Trust (see infograph on page 3). In November the department was named the Nursing Times ‘Clinical
Research Team of the Year’ (article below). We remain the top recruiting District General Hospital across the ‘North Thames’ and ‘East
of England’ region for 2017/18 and continue to be the top national recruiters for several multi-centred studies (see page 4). This edition
of ‘Research Focus’ covers recent local and national work we have been supporting and the 23 manuscripts that have been published
over the past 3 months. We focus on the latest national funding opportunities for your research ideas and the launch of our ‘Innovate’
newsletter to encourage the development and utilisation of healthcare innovations in the Trust (see page 8).
News
News
Performance
Nursing Times Awards 2017 – Clinical Research Team of the Year!
If you have not already heard the news where have you been the past two months! At the
glittering awards gala held at the Grosvenor Hotel in London on the 2nd
November the work
of our dedicated team of research nurses was recognised as the Nursing Times ‘Clinical
Research Team of the Year 2017’ (Sponsored by the National Institute for Health Research).
To say we are over the moon is an understatement. It was wonderful that so many members
of the nursing team were able to be there on the evening to share in this important milestone
in the history of Research & Development in the organisation. All the finalists; many of them
household names and major teaching hospitals, had strong justification to win the award, so
to fly the flag for Essex and for District General Hospitals was an honour. Our success has
really put the Trust on the map as a centre of research excellence and will undoubtedly lead
to Broomfield being selected as a site for more high quality studies by sponsors in 2018.
Thank you to everyone within the Trust (from porters to plastic surgeons, administrators to
clinical academics) who have helped make this possible and to our research partners at CRN:
North Thames, who fund the majority of our departmental nurses.
Lyn Hinton, MEHT Director of Nursing:
“Well done to our Research and Development team for this outstanding achievement. It is
wonderful to see them recognised on a national platform and is cause for celebration.”
Susan Hamer, NIHR: CRN Director of Nursing, Learning and Organisational Development:
“Following a significant refocus of the clinical research nursing effort, this well-led team has
emerged with ambition, vigour and drive. The patient focus is palpable and a constant
touchstone to the whole team and its new direction.”
Events InnovationsPublications
IN THIS ISSUE
New Studies Page 2
Research Forum Page 2
Sharing Good Practice Page 2
A Year In Numbers Page 3
Mentions in Dispatches Page 4
Research Training Page 5
Renal Symposium Page 5
Publications Page 6
Research Funding Page 7
Innovation Page 8
New HRA Guidance Page 9
Value for Money Page 9
Newsletter
Winter
2018
“Delivering today’s research into tomorrow’s healthcare”

2. Research, Development & Innovation Page 2 of 9
Recently Opened Studies (1st
October 2017 – 31st
December 2017)
NIHR portfolio adopted studies:
• ‘SIGNUM: Determinants of prognosis in stroke’ (NIHR 30705), Dr Kirthivasan Ramanathan.
• ‘LIK016 in Type II diabetic patients with heart failure’ (NIHR 32727), Dr Reto Gamma.
• ‘Lysin CF-301 for treatment of staphylococcus aureus bacteremia’ (NIHR 32152), Dr Wael Elamin.
• ‘CC-486 in myelodysplastic syndromes’ (NIHR 30911), Dr Waseem Nagi.
• ‘IRONMAN: IV iron in patients with heart failure & iron deficiency’ (NIHR 31744), Dr Reto Gamma.
• ‘TRACC: Predicting relapse in early colorectal cancer’ (NIHR 20443), Dr Srinivasan Gopalakrishnan.
• ‘MonarchE: Abemaciclib in breast cancer’ (NIHR 31125), Dr Abdel Hamid.
• ‘OPTIMA: Optimal personalised treatment of early breast cancer’ (NIHR 12255), Dr Abdel Hamid.
• ‘REALISM: Retrospective review of treatment pathways for Myelofibrosis’ (NIHR 36163), Dr Waseem Nagi.
Non-NIHR portfolio studies:-
• ‘Velopharyngeal Dimensions in Patients with 22q11 deletion syndome’, Mr Loshan Kangesu.
• ‘Seasonal Variation of Pseudomonal infections’, Dr Wael Elamin.
NIHR National Event – Sharing Good Practice - London, 2nd November 2017
Broomfield Hospital were one of ten NHS Trusts invited to attend a Clinical
Research Network Coordinating Centre event in London to share good practice and
local innovations in improving research engagement within their organisations. We
were delighted to be invited and to represent both Essex and District General
Hospitals at the event alongside colleagues from Barts, Birmingham, Imperial,
Ipswich, Leeds, Northwick Park, Sheffield and St. George’s. At the event the team
presented the journey the Trust’s R&D department had been on over recent years
and the small changes implemented into routine day-to-day practice that when
combined have led to the step-improvements in the quality and quantity of
research being currently supported at Broomfield Hospital. The talk was very well
received by the audience who asked a lot of questions.
‘Mid Essex Success Regime Research Forum’ – Southend, 11th October 2017
As part of the local healthcare transformation, the Research and Development
Departments at Basildon, Broomfield and Southend Hospitals held an inaugural
‘Essex Success Regime Research Forum’ meeting in Southend on the 11th
October 2017. The forum comprised of posters prepared by the three Trusts to
discuss local research strengths and presentations were made by Dr Celia
Skinner (Chief Medical Officer), Prof. Selim Cellek (Anglia Ruskin University),
Dr Sharon Barrett (CRN: North Thames) discussing what could be achieved
through greater local collaboration between the Trusts and Essex Universities.
The poster comparing research at the three Trusts is included on the final page
of this newsletter.
Further ‘Research Forum’ meetings will be organised over the coming year at
Broomfield Hospital and Basilson Hospital giving more staff the opportunity to
contribute to the discussions on how research can further grow across the three
Trusts to enhance patient care and treatments.
(From left) Tracey Camburn, Christine Catley,
Joanne Topliffe & Lauren Perkins

3. Research, Development & Innovation Page 3 of 9

4. Research, Development & Innovation Page 3 of 10
Recognising Recent Recruitment Performances
ASCOT (17783) - Lifestyle study for cancer survivors.
• Oncology. PI: Tracey Camburn, R&D Office Lead: Lauren Shillito.
• Top recruiting site nationally (of 9 sites); recruiting a total of 1,635participants to date.
The 65 Trial (34222) – Permissive hypotension in critically ill patients.
• Critical Care, PI: Jay Radhakrishnan, R&D Office Lead: Fiona McNeela.
• Top recruiting site nationally (of 63 sites); recruiting a total of 36 participants to date.
ExPEC (33422) – Patients with ExPEC disease following TRUS-PNB.
• Urogenital. PI: Bill McAllister, R&D Office Lead: Lauren Shillito.
• Top recruiting site nationally (of 23 sites); recruiting a total of 177 participants to date.
PORUS-aRCC (31161) - Advanced renal cell carcinoma study.
• Oncology. PI: Gopalakrishnan Srinivasan, R&D Office Lead: Lauren Shillito
• Top recruiting site nationally (of 20 sites) in 2017/18; recruiting a total of 9 participants.
PREPARE-ABC (10674) –Exercise programmes for accelerating recovery after major abdominal cancer surgery
• Oncology. PI: Toby Hammond, R&D Office Lead: Sian Gibson, Yvonne Lester.
• Top recruiting site nationally (of 22 sites) in 2017/18; recruiting a total of 17 participants.
XILO-FIST (16122) – Xanthine oxidase Inhibition Following Ischaemic Stroke and Transient ischaemic attack
• Stroke. PI: Kirthivasan Ramanathan, R&D Office Lead: Jo Topliffe.
• Top recruiting acute site nationally (of 21 sites) in 2017/18; recruiting a total of 7 participants.
Cleft Palate Speech (16436) - Identification of factors associated with speech disorder-cleft palate.
• Paediatrics. PI: Marie Pinkstone, R&D Office Link: Helen Gerrish, Karen Cranmer, Natalie Fox
• Top recruiting site in 2017/18 (of 14 sites); recruiting a total of 48 participants to date.
Cleft-Q (18483) - Patient-Reported Outcome Measure for Cleft Lip and/or Palate Patients
• Paediatrics. PI: Loshan Kangesu, R&D Office Link: Helen Gerrish, Karen Cranmer, Natalie Fox
• Top recruiting site (of 43 sites) during 2017/18; recruiting 81 participants to date.
DARE (33815 ) - Diabetes Alliance for Research in England, the causes and complications of Diabetes.
• Diabetes, R&D Office Link: Helen McIver
• Tennyson House Surgery, Chelmsford (Mid Essex CCG) is the top
recruiting primary care site (of all participating GP practices across
76 CCGs) across England recruiting 300 participants.
• On Thursday 16th November 2017, Ade Aderonke (Research
Delivery Manager, Clinical Research Network: North Thames)
visited Tennyson House Surgery and presented the practice
manager, Rebecca Pittuck, with a certificate to mark their success.
1st
1st
1st
1st
1st
1st
1st
1st
Performance
Ade Aderonke (L.) & Rebecca Pittuck (R.)
1st

5. Research, Development & Innovation Page 5 of 9
Good Clinical Practice Training
Working to the principles of Good Clinical Practice (GCP) are the cornerstone for anyone
involved in research. All people new to research must receive introductory training in
GCP and update (refresher) training every 2 years, or proportionate training pertinent to
their duties in supporting the research.
We run several taught and online ‘Introductory’ and ‘Refresher’ training courses to support
you in understanding and applying the principles of GCP into practice.
Our forthcoming classroom courses are on:-
‘Introduction to GCP’ Thursday 25th January 2018, 9.30am-4.00pm, Lecture Theatre 1, MAU
6 CPD points Friday 13th April 2018, 9.30am-4.00pm, Olga Rippon Room, MAU
Friday 13th July 2018, 9.30am-4.00pm, Olga Rippon Room, MAU
Friday 12th October 2018, 9.30am-4.00pm, Olga Rippon Room, MAU
‘Refresher GCP Training’ Friday 26th January 2018, 2.00-5.00pm, Olga Rippon Room, MAU
4 CPD points Thursday 12th April 2018, 2.00pm-5.00pm, Olga Rippon Room, MAU
Thursday 12th July 2018, 2.00pm-5.00pm, Olga Rippon Room, MAU
Thursday 11th October 2018, 2.00pm-5.00pm, Lecture Theatre 1, MAU
If none of the above dates are convenient, we are happy to schedule further events. The
courses are open to members of all local NHS Trusts, GP practices and academia to attend.
For further information, or to register for online training contact
Paul Roberts on ext. 6454 or at paul.roberts2@meht.nhs.uk
Events
Regional Renal & Urology Research Symposium – Chelmsford, 30th
January 2018
The Clinical Research Network for North Thames are holding their first ‘Renal &
Urology Research Symposium’ at Broomfield Hospital on Tuesday 30th
January
(9am to 5pm in the Medical Academic Unit). Broomfield Hospital was selected to
host the event due to the Trust being the highest recruiting NHS organisation into
renal and urology studies within the region during 2017 thus far. Sessions on the
day will include:
• Key Note lecture from Prof John Feehally (Leicester) on the ‘UK Renal
Research Strategy’
• Prof Martin Wilkie (Sheffield) speaking about the UKPDOPPS study
• The Mid Essex Research Team
• Patient experience and story
• EXPEC, SIMPLIFIED trial case studies
• Future studies
This event is open to all investigators and their research teams working in the CRN North Thames area.
Further details about the programme & how to register can be found on the link below:-
https://www.eventbrite.co.uk/e/crn-north-thames-renal-urology-symposium-tickets-36655271905?aff=es2

6. Research, Development & Innovation Page 6 of 9
Known Research Publications Authored by Trust Staff in Q3 (October 2017 - December 2017)
Publications
E
Acquaah, F., Pinder, R., Cooper, C., Cook, J., Gardiner, M.D., Sierakowski, A., Zweifel C., Jain, A., Greig, A. (2017). ‘Trainees experience of a national multi-
centre randomised controlled pilot trial in plastic surgery.’ International Journal of Surgery 47: S68.
Albert, V., Mndolo, S., O'Sullivan, E., Wilson, I., Walker, I. (2017). ‘Donating medical equipment to low-income countries: Getting it right.’ International
Journal of Surgery 47: S69.
Ali, E., Macdowell, A., Pagonis, T. (2017). ‘A novel model for a hub-and-spoke spinal service and improvements in the treatment of spinal pathology in a rural
hospital setting.’ Rural and Remote Health 17: 4273.
Ali, E., Raghuvanshi, M. (2017). ‘Treatment of open upper limb injuries with infection prevention and negative pressure wound therapy: a systematic review.’
Journal of Wound Care 26: 712-719.
Al-Tawil, K., Lopez, D., Blackman, M., Suresh, S. (2017). ‘Oblique "Scotty dog" versus antero-posterior (AP) views in performing x-ray guided facet joint
injections.’ Journal of Clinical Orthopaedics and Trauma [epub ahead of print].
Bickerton, S., Nizamoglu, M., Frew, Q., Borrows, E., Bangalore, H., Martin, N., Barnes, D., El-Muttardi, N., Dziewulski, P. (2017). ‘What are the intensive care
requirements for paediatric burns in a regional burns service?’ International Journal of Surgery 47: S9.
Carroll, C., Jagatiya, M., Kamel, D., Siddiqi, J. (2017). ‘A parapharyngeal space schwannoma arising from the vagus nerve: A case report.’ International Journal
of Surgery Case Reports 41: 22-25.
Das, D., Emamdee, R., Nair, R. (2017). ‘Adductor canal block combined with ultrasound guided posterior and anteromedial knee joint infiltration with local
anaesthetic for analgesia after primary knee arthroplasty.’ Regional Anesthesia and Pain Medicine 42: e146.
Das, D., Emamdee, R., Nair, R. (2017). ‘The morphine sparing effect of truncal regional blocks in free flap reconstructive surgery.’ Regional Anesthesia and Pain
Medicine 42: e147.
Elshaer, M., Gravante, G., Tang, C.B., Jayanthi, N.V. (2017). ‘Totally minimally invasive two-stage esophagectomy with intrathoracic hand-sewn anastomosis:
short-term clinical and oncological outcomes.’ Diseases of the Esophagus [Epub ahead of print].
Gopal, A., Redman, M., Cox, D., Foreman, D., Elsey, E., Fleming, S. (2017). ‘Academic poster design at a national conference: a need for standardised
guidance?’ The Clinical Teacher 14: 360-364.
Greig, A., Gardiner, M.D., Sierakowski, A., Zweifel, C.J., Pinder, R.M., Furniss, D., Cook, J.A., Beard, D., Farrar, N., Cooper, C.D., Jain, A., NINJA Pilot
Collaborative. (2017). ‘Randomized feasibility trial of replacing or discarding the nail plate after nail-bed repair in children.’ British Journal of
Surgery 104: 1634-1639.
Heptinstall, L., Carroll, C., Siddiqi, J., Kamel, D., Petkar, M. (2017). ‘Sclerosing Mucoepidermoid Carcinoma of the Submandibular Gland Presenting as Chronic
Sialadenitis: A Case Report and Review of Literature.’ Head and Neck Pathology 11: 506-512.
Kordzadeh, A., Panayiotopolous, Y. (2017). ‘S-shaped versus conventional straight skin incision: Impact on primary functional maturation, stenosis and
thrombosis of autogenous radiocephalic arteriovenous fistula: Impact of incision on maturation, stenosis & failure of RCAVF. Study design:
Prospective observational comparative.’ Annals of Medicine and Surgery 22: 16-21.
Martin, N.A., Falder, S. (2017). ‘A review of the evidence for threshold of burn injury.’ Burns 43: 1624-1639.
Mehrotra, S., Emamdee, R., Nair, R., Das, D. (2017). ‘Ultrasound workshop for senior anaesthetist: Budget course.’ Regional Anesthesia and Pain Medicine 42:
e160.
Naji, S., Loh, C.Y.Y., Tare, M. (2017). ‘The exquisitely painful fingertip - subungual glomus tumours.’ International Wound Journal 14: 1405-1406.
Nizamoglu, M., Ward, J.A., Frew, Q., Gerrish, H., Martin, N., Shaw, A., Barnes, D., Shelly, O., Philp, B., El-Muttardi, N., Dziewulski, P. (2017). ‘Improving
mortality outcomes of Stevens Johnson syndrome/toxic epidermal necrolysis: A regional burns centre experience.’ Burns [epub ahead of print].
Penry, S. (2017) ‘CT or MRI? A Comparison’. Synergy: Imaging & Therapy Practice Dec: 5-10.
Perkins, V., Hawlin, J., Farhangmehr, N., Jayanthi, V. (2017). ‘Post-operative care of the oesophago-gastric cancer patient-are junior doctors competent and
confident in their approach?’ International Journal of Surgery 47: S93.
Ranjit, S., Rashid, F., Lorenzi B., Charalabopoulos, A. (2017). ‘Current standard of basic laparoscopic skills training amongst junior doctors in the UK.’
International Journal of Surgery 47: S72-73.
Shroff, N., Shroff, R., Thakur, V., Thakur, Y., Penketh, R., Tas, B. (2017). ‘Smartphone Speculum: Design, Development and Initial Experience.’ Journal of
Minimally Invasive Gynecology 24: S62.
Siddika, A., Conn, G., Pearson, T. (2017). ‘Transanal minimally invasive surgery (TAMIS): Single center initial experience of 30 cases.’ Colorectal Disease 19:
109.
Siddika, A., Warburton, S., Teare, L., Siddiqi, S. (2017). ‘Surgical site infection in colorectal surgery: The preventive bundle is an effective approach to surgical
site infection reduction and health care cost savings.’ Colorectal Disease 19: 236.
Singh, H.K.S.I., Randhawa, S., Pittathankal, A., Bonner, C., Syal, S. (2017). ‘Should we take a minimum of three sentinel lymph nodes?’ International Journal of
Surgery 47: S17.
Tan, A.M., Loh, C.Y.Y., Nizamoglu, M., Tare, M. (2017). ‘A challenging case of calcific myonecrosis of tibialis anterior and hallucis longus muscles with a chronic
discharging wound.’ International Wound Journal [epub ahead of print].
Tang, S.S., Kaptanis, S., Haddow, J.B., Mondani, G., Elsberger, B., Tasoulis, M.K., Obondo, C., Johns, N., Ismail, W., Syed, A., Kissias, P., Venn, M.,
Sundaramoorthy, S., Irwin, G., Sami, A.S., Elfadl, D., Baggaley, A., Remoundos, D.D., Langlands, F., Charalampoudis, P., Barber, Z., Hamilton-
Burke, W.L.S., Khan, A., Sirianni, C., Merker, L.A.G., Saha, S., Lane, R.A., Chopra, S., Dupré, S., Manning, A.T., St, John, E.R., Musbahi, A., Dlamini,
N., McArdle, C.L., Wright, C., Murphy, J.O., Aggarwal, R., Dordea, M., Bosch, K., Egbeare, D., Osman, H., Tayeh, S., Razi, F., Iqbal, J., Ledwidge,
S.F.C., Albert, V., Masannat, Y. (2017). ‘Current margin practice and effect on re-excision rates following the publication of the SSO-ASTRO
consensus and ABS consensus guidelines: a national prospective study of 2858 women undergoing breast-conserving therapy in the UK and
Ireland.’ European Journal of Cancer 84: 315-324.
Thakur, Y., Karunaratne, C., Nicholls, S., Thakur, V. (2017). ‘Minitouch endometrial ablation: Review of outcomes and resource usage at Basildon University
Hospital.’ Journal of Minimally Invasive Gynecology 24: S137.
Thomas, R.J., Creasy, H., Dheansa, B. (2017). ‘Community over-the-counter management of burns wounds: Is there an education gap?’ Burns 43: 1601-1602.
Upadhyaya, K., Hendra, H., Wilson, N. (2018). ‘A high impact intervention for a high impact intervention: Improving documentation of peripheral venous
access insertion in theatre.’ Journal of Infection Prevention 19: 43-45.
Win, T.S., Nizamoglu, M., Maharaj, R., Smailes, S., El-Muttardi, N., Dziewulski, P. (2017). ‘Relationship between multidisciplinary critical care and burn
patients survival: A propensity-matched national cohort analysis.’ Burns [epub ahead of print].
Zhong, J., Atiiga, P., Alcorn, D.J., Kay, D., Illing, R., Breen, D.J., Railton, N., McCafferty, I.J., Haslam, P.J., Wah, T.M. (2017). ‘Cross-sectional study of the
provision of interventional oncology services in the UK.’ BMJ Open 7: E016631.

7. Research, Development & Innovation Page 7 of 9
Funding£
National Research Grant Funding Opportunities & Deadlines
Below are some of the currently open nationally competitive research funding calls that are applicable to the Trust. The list below
is by no means an exhaustive list of opportunities; just the main (NIHR badged) ones. You are encouraged to contact the R&D
office if seeking funding to support your research idea at the earliest opportunity. Especially if your proposed study is likely to
need the services of a Clinical Trials Unit. We are here to help search for the most appropriate funding opportunities that are
available both nationally and internationally to you.
NIHR ‘RESEARCH FOR PATIENT BENEFIT’ (UP TO £350,000)
Researcher-led call. All specialities. Two stage application process.
• Purpose is to realise, through evidence, the huge potential for improving, expanding and strengthening the way that
healthcare is delivered for patients, the public and the NHS.
• Current Competition 35: deadline 21st March
http://www.nihr.ac.uk/funding-and-support/funding-for-research-studies/how-to-apply/research-programmes/research-
for-patient-benefit/
NIHR ‘PUBLIC HEALTH RESEARCH PROGRAMME’
Researcher-led call. All specialities.
17/161 - evidence synthesis: deadline 27th
March
https://www.nihr.ac.uk/funding-and-support/funding-opportunities/17151-public-health-research-programme-evidence-
synthesis/7531?diaryentryid=28304
NIHR ‘EFFICACY AND MECHANISM EVALUATION PROGRAMME’
Researcher-led call. All specialities.
17/145 Researcher-led: deadline 27th
March
www.nihr.ac.uk/funding-and-support/current-funding-opportunities
NIHR ‘HEALTH TECHNOLOGY ASSESSMENT PROGRAMME’
Researcher-led call. All specialities.
17/148 Researcher-led: deadline 28th
March
Commissioned call for proposals that address specific topics, identified by the HTA
17/136 - Sepsis: deadline 28th
March 2018.
17/133 - Scanning confocal ophthalmoscopy for diabetic eye screening: deadline 28th
March 2018.
17/134 - ID of older patients likely to require enhanced care on discharge from hospital: deadline 28th
March 2018.
17/137 - Dose of oxytocin during induction of labour: deadline 28th
March 2018.
17/140 - Optimising the use of statin therapy in cardiovascular disease prevention: deadline 28th
March 2018.
https://www.nihr.ac.uk/funding-and-support/current-funding-opportunities/?&start=1&custom_in_Programme=5239
BRITISH HEART FOUNDATION – PROJECT GRANTS (<£300,000)
No deadline, submit application when ready
https://www.bhf.org.uk/research/information-for-researchers/what-we-fund/project-grants
THE STROKE ASSOCIATION – PROJECT GRANT AWARD (UP TO £210,000)
Researcher-led call.
Deadline for applications: February 2018.
https://www.stroke.org.uk/research/looking-funding/project-grants-0
JOINT STROKE ASSOCIATION / BRITISH HEART FOUNDATION – ‘CLINICAL STUDY IN STROKE AWARD’ (UP TO £1,500,000)
Researcher-led call.
Deadline for applications: February 2018.
https://www.stroke.org.uk/research/looking-funding/joint-stroke-association-british-heart-foundation-clinical-study-
stroke-0
For further information and support in writing an application for any of the above, or to learn about other
funding avenues, please contact Paul Roberts (Home-Grown Research Project Manager) on
paul.roberts2@meht.nhs.uk or ext. 6454 at the earliest convenience.

8. nnrnrnynyr
‘Medtech Accelerator Health Hack – Surgical Innovations’ 18th & 19th January, Cambridge
The Medtech Accelerator Health Hack workshops are designed to engage a wide community of stakeholders, focused on
stimulating innovation within the NHS, through the identification and development of innovative new products and services with
the potential to meet unmet clinical needs and generate commercial benefit.
There is increasing pressure on surgical services, the cost of delivering surgery and patient waiting times. Theatres and intensive
care staff provide a vital role supporting all surgical activity across a range of elective, trauma, emergency and day care procedures.
We are seeking medical technologies that result in dramatically lower-cost products and services within the theatres, anaesthesia
and critical care setting but without comprising quality.
https://www.eventbrite.co.uk/e/medtech-accelerator-health-hack-surgery-tickets-39658760420?aff=es2
MedTech Accelerator Programme Funding – ‘Call 4’
Following the success of the previous calls, Health Enterprise East are pleased to announce
‘Call 4’ of the MedTech Accelerator Programme; a new proof of concept financial awards
scheme to progress medical device, diagnostics, software and e-health ideas developed
primarily from within the NHS.
With a funding pot of £1.5 million, awards on offer range from £15K-£125K. The MedTech Accelerator will support and finance
technology ideas at a very early stage in their development in order to maximise the potential for success in bringing new life
enhancing technologies to patients. Awards are aimed at supporting early proof of concept work; which typically includes:-
Market Research > IP Protection > Product and Market Validation > Prototype Development & Testing
They hope that through their support, new technology ideas in the NHS can be supported and eventually spun out into being new
commercial companies in a similar way to how Universities have been so successful over the past few decades. Time to bring your
innovations forward and be fully supported in turning your ideas into a commercial reality!
The deadline for ‘Call 4’ applications is Thursday 1st
March 2018, with short-listed applicants invited to present to the awards panel
on the 27th
April in Cambridge.
For more information please contact the R&D office at the earliest opportunity so that we can work up your application with you or
visit the MedTech Accelerator website.
Innovations
New MEHT Innovation Newsletter - INNOVATE
Arriving in you inbox soon will be our new INNOVATE newsletter. The newsletter’s
aim is to promote ideas for innovations within the Trust. Innovation in the NHS
can take different forms. Often innovation may be related to process and service
improvement (i.e. educational tools), but it may also take place through the
development of new medical technology (i.e. a medical device) or clinical tools
(i.e. app, software etc). Topics covered in the newsletter include:-
• What is an innovation?
• How to make money from your innovation.
• About Health Enterprise East (our Trust innovation partners).
• A local success story- EarFold.
• Innovations at DGHs across the East of England.
Application Deadline – Thursday 1st March 2018

9. Its official...MEHT most cost-efficient recruiter to studies in ‘CRN: North Thames’ region
New guidance on the requirement for Good Clinical Practice training
In November the Health Research Authority (HRA) issued a joint statement with the Medicines &
Healthcare products Regulatory Agency (MHRA) advocating a proportionate approach to the
application of Good Clinical Practice (GCP) researcher training. It has been created in partnership
with the Devolved Administrations and is supported by a number of organisations including the
Academy of Medical Sciences and the Ethical Medicines Industry Group.
Good Clinical Practice (GCP) is an international ethical and scientific quality standard for designing,
conducting, recording and reporting clinical trials that involve the participation of human subjects.
The HRA are constantly looking to streamline the process of applying for research approval and
making procedures as simple and straightforward as possible – with this GCP statement just one
example. The guidance makes the following statements:-
• We have listened to key stakeholders, many of whom have told us how frustrating it can be to spend valuable time
completing training they do not need.
• Only researchers engaged in clinical trials of an investigational medicinal product study (aka drug study) must undertake
training in Good Clinical Practice.
• The guidance makes no reference to the frequency of refresher (update) training.
At MEHT we aspire to the best standards in conducting research. We believe that this HRA document creates a dual-standard
for how participants in drug trials are treated when compared to those taking part in all other studies, when in truth the
differences between the two are few. The Trust will continue to offer pragmatic and proportionate research training (in
partnership with the NIHR) to all research active staff flexibly via group training, e-modules and through 1-1 bespoke training.
During 2017, 149 members of staff received training in Good Clinical Practice. The training was evaluated as excellent with
100% of attendees recommending this training to others.
https://www.hra.nhs.uk/about-us/news-updates/updated-guidance-good-clinical-practice-gcp-training/
and finally…
  
Research, Development & Innovation
C254 West Wing,
Broomfield Hospital,
Court Road,
Chelmsford,
Essex, CM1 7ET
 Telephone: (01245) 515136
 E-mail: research@meht.nhs.uk
 Website: www.meht.nhs.uk/research
 Twitter: @MEHTresearch
A report published by ‘NIHR Clinical Research Network: North Thames’ in
November praises MEHT as being the NHS Trust that offers the greatest ‘value
for public money’ in the conduct of research during 2017.
On average, each patient recruited into a study at MEHT costs the NIHR £36. A
figure much lower than the regional average of £91 (range £36-£248) across
the 5 Large-Teaching Hospitals, 11 District General Hospitals, 7 Community /
Mental Health Trusts & 20 Clinical Commissioning Groups that make up the
North Thames region.
By comparison our colleagues at BTUH and SUHFT had a ‘value for money’
score of £66 and £242 respectively.
The trinity of delivering high-quality research to as many of our patients
(quantity) as possible whilst making the most efficient use of the public
money that funds research is the hallmark of research at Broomfield Hospital.

10. NIHR Portfolio Research – A Tale of Three Trusts
Research Quality, Quantity & Value for Money
Basildon University Hospital Southend University HospitalBroomfield Hospital
28%28%
37% 37%
35%35%
• Have hosted 213 studies (39% Int./ 50% Obs./ 11% Com.).
• Key areas (studies): CV (41), Cancer (38), MSK (31),
Reproductive (12), Renal (11) + 20 other specialties.
• NIHR League Table 2017/18: 46th / 152 Acute Trusts
• Summary: Consistently high research profile,
demonstrating quality, quantity & value for money.
(Slight fall in interventional recruitment past 3 years.)
• Have hosted 169 studies (34% Int./ 47% Obs./ 19% Com.).
• Key areas (studies): Cancer (57), MSK (14), Renal (13),
Surgery (10), CV (9) + 17 other specialities.
• NIHR League Table 2017/18: - 40th / 152 Acute Trusts.
• Primary Care Research Host: ~1K participants / annum.
• Summary: High & growing research profile, delivering
quality , quantity and great value for money.
• Have hosted 212 studies (42% Int/ 43% Obs/ 15% Com.).
• Key areas (studies): Cancer (61), MSK (32) , Stroke (22),
Renal (16), Ophthalmology (13) + 22 other specialties.
• NIHR League Table 2017/18: 120th / 152 Acute Trusts
• Summary: Research outputs erratic (quality) over past
3 years which has impacted on ‘value for money’ in
2017/18; despite high recruitment seen in 2016/17.
• The Success Regime is a national initiative that was first announced in the ‘NHS Five Year Forward View’ in 2015. The Essex Success Regime (ESR) brings our separate NHS acute organisations together as one entity.
• As local Research & Development offices we now have an opportunity to make system changes and embrace new collaborative, more patient centric and cost-efficient ways of working to maximize our collective ability
to offer more of our patients the opportunity to partake in world class research as a routine care option across all clinical areas.
• This poster looks at the level of research engagement at each ESR acute Trust in high quality ‘NIHR portfolio adopted’ research over the past 4-5 years. The poster looks at the ‘Quality’ (balance between interventional,
observational & commercial studies), ‘Quantity’ (% of patients treated engaged in research) & ‘Value for Money’ (cost of each participant recruited); taking into account ‘NIHR Activity Based Funding’.
• Combined NHS Trust one of the largest in the UK.
• However, research outputs lower when compared to similar
sized acute Trusts (mainly due to their long standing links to
world class universities as teaching hospitals).
• Opportunity to forge stronger links with Anglia Ruskin
University (new Medical School) and with other leading
academic centres in our areas of research strength.
• Key to achieving this is development of more ‘home-grown
research’ attracting nationally (i.e. NIHR) and internationally
(i.e. EU) competitive research grant funding.
• Training key to this. Developing a research engaged workforce
(consultants, nurses, allied healthcare professionals) with the
confidence and support to excel.
• Hospital R&D offices act in spirit of ‘one for all and all for one.’
13th September 2017
434 Unique studies
43 Studies open at
all sites (10%)
68 Studies open at
2 sites
MEHT
169
Studies
SUHFT
212
Studies
BTUH
213
Studies
NIHR ‘Value for Money’ 2017/18 Future – Adding Value Together