1. Selections
from:
The
85%
Solution
By
Dan
Purser
MD

2. ROOT
CAUSES
OF
THE
MTHFR
MUTATION
THE
CURRENT
HUMAN
race
lives
and
procreates
a
long
time.
I
just
had
a
daughter
and
was
turning
50.
Wow,
was
I
crazy
or
what?
It
wasn’t
that
long
ago
that
the
average
American
lived
to
be
in
their
late
20’s
(three
generations
back),
women
were
getting
married
in
their
teens
and
having
babies,
then
dying
in
child
birth.
Only
one
out
of
ten
children
lived
to
adulthood
–
much
lower
in
other
countries.
Now
we’re
living
into
our
90s
regularly.
With
our
longer
life
expectancy
we
are
passing
on
more
gene
defects.
There’s
no
doubt.
It’s
just
the
way
it
is.
MTHFR
(ACTUALLY
called
MethyleneTetraHydroFolate
Reductase
Enzyme
Deficiency)
came
along
in
northern
Europe
several
hundred
generations
ago
and
now
has
blown
up
(85%
of
the
population
carries
a
variant
or
at
least
a
SNP
of
this
gene
mutation1
(stands
for
Single
Nucleotide
Polymorphism)
or
more
appropriately
called
a
transcription
error,
5%
carries
both
genes
so
are
homozygous).
And
oddly
enough
49%
of
the
Latino
or
Hispanic
population
are
carriers
or
have
the
MTHFR
disease.
Well,
I
guess
it’s
not
really
a
disease
or
mutation
–
it’s
actually
just
a
DNA
replication
or
copying
problem
called
a
TRANSCRIPTION
ERROR.
Wow,
what
an
error.
Methylation
is
probably
THE
most
important
enzyme
function
our
body
makes
–
it
controls
so
much
–
and
is
deeply
and
inherently
tied
to
our
energy
levels,
both
perceived
and
actual.
You
always
have
to
wonder
how
mutations
survive
–
especially
cruddy
ones
like
this
one
–
studies
have
shown
that
it’s
a
survival
gene
mutation
against
colon
cancer2
(crazy
right?
But
I
knew
it
had
to
give
some
type
of
x-­‐man
powers).

3. And
why
does
your
doctor
not
know
about
this
or
recognize
it?
I’m
not
sure.
I
think
my
(figurative)
brothers
and
sisters
in
the
medical
field
are
just
too
busy
with
getting
patients
out
of
the
office
–
they
are
overwhelmed
seeing
60
patients
a
day
(I
never
see
more
than
8).
This
book
hopefully
details
the
diagnosis
and
diseases
and
treatments
of
this
disease
more
thoroughly
to
make
it
all
more
comprehensible
for
you
and
I.
HOMOZYGOUS
C677T
PROTOCOL
©
BY
DAN
PURSER
MD
1. Get
your
SpectraCell
Comprehensive
Micronutrient
Panel
-­‐-­‐
critical.
2. Get
your
Whole
Blood
Histamine
Level.
3. Get
your
Homocysteine
Level.
4. Start
with
Thorne
Research
OTC
Basic
Nutrients
2
Day
Vegetarian
Capsules™
at
one
per
day
(one
capsules
is
the
easiest
and
most
natural
way
to
get
a
TINY
AMOUNT
OF
NATURAL
FOLATE
IN).
5. Add
fish
oil
–
Source
Naturals
Arcticpure™
Omega-­‐3
1125
Fish
Oil,
1,125mg
–
start
with
one
per
day
(with
meals)
and
after
a
few
weeks
go
to
twice
a
day
(to
prevent
clotting
and
strokes
and
other
thrombotic
events)
6. Add
probiotics
-­‐-­‐
Natren™
Healthy
Trinity
Dairy
Free
Capsules
–
2
in
the
morning
or
two
at
night
–
take
with
food.
7. Add
one
Doctor's
Best™
Best
Nattokinase
(2,000
Fu),
Vegetable
Capsules,
90-­‐Count
–
one
per
day
to
reduce
clotting
risk
nautrally.
8. After
1-­‐2
weeks,
if
no
nausea,
add
or
start
on
MegaFolinic™
Acid
(try
half
a
one
per
day)
9. After
two
week
with
no
problems
(nausea,
aches,
pains,
etc.)
add
Homocystex™
Plus
at
one
per
day.
Take
first
thing
in
the
morning.

4. 10. After
one
week
increase
the
Homocystex™
Plus
to
two
per
day
11. When
your
Homocystex™
Plus
bottle
is
empty
please
switch
over
to
Homocysteine
Supreme™
(purchase
from
your
doctor)
at
one
per
day
–
then
immediately
go
to
two
per
day.
12. Nauseated
or
feel
funky?
Add
KAL™
NIACIN
at
50
mg
a
dose
(watch
for
flushing
–
just
a
weird
side
effect).
Take
up
to
6
per
day
(they’re
safe
just
may
flush
you
into
misery).
13. Is
your
Whole
Blood
Histamine
level
high?
You
aare
n
“undermethylator”.
Start
with
methionine
500
mgm
capsules
first.
If
two
each
day
are
well
tolerated
then
change
to
Doctor’s
Best™
SAMe
(and
avoid
extra
methylfolate
or
especially
folic
acid!).
14. Is
your
Whole
Blood
Histamine
level
low?
You
are
an
“overmethylator”.
Then
add
Active
B12™
1-­‐3
per
day
–
but
do
it
SLOWLY.
15. After
a
few
weeks
and
feeling
the
benefits
(you
will)
please
take
an
extra
Homocysteine
Plus™
at
noon
before
lunch
or
with
lunch.
16. After
a
few
more
weeks
try
FOUR
Homocysteine
Plus™
per
day
(2
in
AM
and
2
at
lunch).
If
nausea
or
problems
back
it
back
down
to
two
or
three
per
day.
17. Add
other
vitamins
as
needed
according
to
the
SpectraCell®
Results.
18. Don’t
forget
to
add
Niacin
(50
mg)
or
B6
(in
the
form
of
hydroxycobalamin)
if
nausea
occurs.

5. Patient
1
The
genetic
testing
I
ordered
afterward
–
confirming
my
suspicions.

7. Patient
2

10.
1
No
author
listed.
Accessed
13
May
2015
online
at
http://www.gbhealthwatch.com/GND-­‐Cardiovascular-­‐Diseases-­‐
MTHFR.php
2
Osian
G,
Procopciuc
L,
et
al.
C677T
and
A1298C
mutations
in
the
MTHFR
gene
and
survival
in
colorectal
cancer.
J
Gastrointestin
Liver
Dis.
2009
Dec;18(4):455-­‐60