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How to deal with sickle cell disease during
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Sickle cell disease also called sickle cell anemia is an
autosomal recessive disorder. It is more likely to be a
blood disorder passed from mother to child. This kind
of blood disorder is very painful and intolerable for
pregnant women with SCD(Sickle cell disease).
 
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Table of Contents
1. Why is sickle cell disease autosomal recessive?
2. Why does it occur?
3. Causes of sickle cell disease
4. How do you know SCD or SCT will be passed to your child or not?
5. Effects of sickle cell disease in pregnancy
6. What are the normal symptoms of SCD?
7. A complication of sickle cell disease during pregnancy
7.1. The complications in pregnant women are like;
7.2. The complications seen in a developing baby are like;
8. How to nd out you are having sickle cell disease or sickle cell traits?
8.1. Swab test
8.2. Family history collection
8.3. .Preimplantation diagnosis
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Why is sickle cell disease autosomal recessive?
 
It is called recessive. Because this disease is
inherited from the parents. And the parents are
responsible for the transfer of sickle cell disease to
the child. This type of blood disorder is either
SCD(sickle cell disease) or SCT( sickle cell traits).
Normally, the pregnant mother who has SCT delivers
a healthy baby. And the mother with SCD needs to
consult a genetic counselor.
 
Why does it occur?
 
The normal red blood cell contains globin protein.
These are called hemoglobin.it carries oxygen to the
body.
 
The healthy and normal red blood cells are round in
shape. They are also very smooth and exible. It
looks like a full moon and circulates easily through
the blood vessels.
 
But the sickle cell contains abnormal hemoglobin.
They are like sickle shape. It’s like the letter c’.These
abnormal cells are impacted on the capillaries and
8.4. Black and Hispanic
9. Treatment of Sickle cell disease during pregnancy
10. Management of SCD
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
cause hemolysis with local anoxemia. This causes
more pain and lack of oxygen supply to the tissues.
 
Causes of sickle cell disease
 
It is a genetically inherited disease that comes from
the parents to the child through the gene. Genes
basically come in pairs( one from father and one
from mother). These are responsible for the growth
and development of the baby.
 
But, sometimes the gene function becomes altered. It
is called gene mutation. This is mainly responsible
for birth defects and other health problems in the
baby.
 
How do you know SCD or SCT will be passed to
your child or not?
 
If the mother and the father both have sickle cell
disease then the baby will surely suffer from it. but, if
the mother and father have sickle cell traits then the
results are quite different.
 
There will be 75 percent chances that the baby
won’t have sickle cell disease.
50 percent chances are that the baby has sickle
cell traits.
25 percent chances that your baby has sickle
cell disease.
Another 25 percent chances are like, your baby
has neither SCD nor SCT.
 

Effects of sickle cell disease in pregnancy
 
Infertility
Increased risk of abortion
Risk of infections
Preterm deliveries
Preeclampsia and hypertension
Stillbirth
The risk for maternal mortality
Intrauterine growth retardation
Anemia
Increased cardiac output
Vaso-occlusion
 
What are the normal symptoms of SCD?
 
The symptoms of this disease appear at 5 months of
age. But, in some cases, it may vary from individual
to individual.
So, in these cases the normal sign and symptoms are
;
Recurrent pain
Anemia
Delayed growth and puberty
There may be swelling of hands and feet
Frequent infections
Vision problems
Restlessness
Splenomegaly
Cardiomegaly
Non-healing ulcer
Headache
 

A complication of sickle cell disease during
pregnancy
 
As it affects the body organs, there are several
complications related to it.
The complications in pregnant women are like;
Infection in the urinary tract, lungs, and kidney
Gallstone
Cardiomegaly
Anemia
Miscarriage
death
 
The complications seen in a developing baby are
like;
Severe anemia
Poor fetal growth
Preterm birth
Low birth weight
Stillbirth
 
How to find out you are having sickle cell disease
or sickle cell traits?
 
The tests that are very essential to diagnose SCD
and SCT  are very safe and helpful during pregnancy.
 
Swab test
A swab is inserted into the mother’s mouth. And
gently rub against the inside of the cheek. It helps to

collect some cells. This technique is very useful to
nd out SCD.
Family history collection
.Preimplantation diagnosis
It is a screening test of fetal cells in the maternal
blood.
Black and Hispanic
 
In the United States, black people mostly suffer from
sickle cell anemia. 1 in 500 live births and Hispanics
1 in 36,000 live births are having this. Also, the
people having their ancestors from Saudi, Africa,
India, the Caribbean or Central America carry SCD.
 
Treatment of Sickle cell disease during pregnancy
 
Early diagnosis and regular checkups are very
important for the pregnant mother having this
disease.
If the sickle cell trait is present in the baby’s
father then amniocentesis is needed to check if
the baby has the trait or not.
If the mother has sickle cell trait then the doctor
advises the father to do the prenatal screening.
In sickle cell disease, some people need a blood
transfusion to replace their abnormal cells with
normal cells. but, in the case of pregnant women,
it may affect the baby.
During pregnancy, the physician does not
advise taking hydroxyurea. a lower dose may be
recommended.
During labor, the doctor gives intravenous uid
therapy and oxygen therapy and also regularly
checks the fetal signs. 
2 thoughts on “How to deal with sickle cell
disease during pregnancy”
 
Management of SCD
Aspirin 100 mg/day
Folic acid 5mg/day
Vitamin supplementation
Routine urine culture
Parenteral uid therapy
 
 
 
    
 
 
 
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  • 1. Home Âť How to deal with sickle cell disease during pregnancy Disease How to deal with sickle cell disease during pregnancy Share this Sickle cell disease also called sickle cell anemia is an autosomal recessive disorder. It is more likely to be a blood disorder passed from mother to child. This kind of blood disorder is very painful and intolerable for pregnant women with SCD(Sickle cell disease).        Facebook Twitter Pinterest WhatsApp Google+ Table of Contents 1. Why is sickle cell disease autosomal recessive? 2. Why does it occur? 3. Causes of sickle cell disease 4. How do you know SCD or SCT will be passed to your child or not? 5. Effects of sickle cell disease in pregnancy 6. What are the normal symptoms of SCD? 7. A complication of sickle cell disease during pregnancy 7.1. The complications in pregnant women are like; 7.2. The complications seen in a developing baby are like; 8. How to nd out you are having sickle cell disease or sickle cell traits? 8.1. Swab test 8.2. Family history collection 8.3. .Preimplantation diagnosis Select Category Neonatal myasthenia gravis and pregnancy How much breastmilk does your baby need? Harlequin ichthyosis ; Role of ABCA12 gene How to protect your newborn from neonatal jaundice How to manage the gestational diabetes insipidus Neonatal myasthenia gravis and pregnancy - antimalady on How much breastmilk does your baby need? Categories Banner Search Recent Posts Recent Comments Search … antimalady Do better for life HOME BABY DISEASE PEDIATRIC DISEASES ABOUT GUEST POST  Join Our Newsletter Signup today for free and be the rst to get noti ed on new updates. powered by MailMunch First Name * Enter rst name Email * Enter your email Subscribe
  • 2. Why is sickle cell disease autosomal recessive?   It is called recessive. Because this disease is inherited from the parents. And the parents are responsible for the transfer of sickle cell disease to the child. This type of blood disorder is either SCD(sickle cell disease) or SCT( sickle cell traits). Normally, the pregnant mother who has SCT delivers a healthy baby. And the mother with SCD needs to consult a genetic counselor.   Why does it occur?   The normal red blood cell contains globin protein. These are called hemoglobin.it carries oxygen to the body.   The healthy and normal red blood cells are round in shape. They are also very smooth and exible. It looks like a full moon and circulates easily through the blood vessels.   But the sickle cell contains abnormal hemoglobin. They are like sickle shape. It’s like the letter c’.These abnormal cells are impacted on the capillaries and 8.4. Black and Hispanic 9. Treatment of Sickle cell disease during pregnancy 10. Management of SCD Neonatal myasthenia gravis and pregnancy - antimalady on Apnea of prematurity-it’s classi cation and treatment Meningitis : Causes, signs and management - D&B on Apnea of prematurity-it’s classi cation and treatment How much breastmilk does your baby need? - antimalady on How to manage the gestational diabetes insipidus How much breastmilk does your baby need? - antimalady on How to protect your newborn from neonatal jaundice 
  • 3. cause hemolysis with local anoxemia. This causes more pain and lack of oxygen supply to the tissues.   Causes of sickle cell disease   It is a genetically inherited disease that comes from the parents to the child through the gene. Genes basically come in pairs( one from father and one from mother). These are responsible for the growth and development of the baby.   But, sometimes the gene function becomes altered. It is called gene mutation. This is mainly responsible for birth defects and other health problems in the baby.   How do you know SCD or SCT will be passed to your child or not?   If the mother and the father both have sickle cell disease then the baby will surely suffer from it. but, if the mother and father have sickle cell traits then the results are quite different.   There will be 75 percent chances that the baby won’t have sickle cell disease. 50 percent chances are that the baby has sickle cell traits. 25 percent chances that your baby has sickle cell disease. Another 25 percent chances are like, your baby has neither SCD nor SCT.   
  • 4. Effects of sickle cell disease in pregnancy   Infertility Increased risk of abortion Risk of infections Preterm deliveries Preeclampsia and hypertension Stillbirth The risk for maternal mortality Intrauterine growth retardation Anemia Increased cardiac output Vaso-occlusion   What are the normal symptoms of SCD?   The symptoms of this disease appear at 5 months of age. But, in some cases, it may vary from individual to individual. So, in these cases the normal sign and symptoms are ; Recurrent pain Anemia Delayed growth and puberty There may be swelling of hands and feet Frequent infections Vision problems Restlessness Splenomegaly Cardiomegaly Non-healing ulcer Headache   
  • 5. A complication of sickle cell disease during pregnancy   As it affects the body organs, there are several complications related to it. The complications in pregnant women are like; Infection in the urinary tract, lungs, and kidney Gallstone Cardiomegaly Anemia Miscarriage death   The complications seen in a developing baby are like; Severe anemia Poor fetal growth Preterm birth Low birth weight Stillbirth   How to find out you are having sickle cell disease or sickle cell traits?   The tests that are very essential to diagnose SCD and SCT  are very safe and helpful during pregnancy.   Swab test A swab is inserted into the mother’s mouth. And gently rub against the inside of the cheek. It helps to 
  • 6. collect some cells. This technique is very useful to nd out SCD. Family history collection .Preimplantation diagnosis It is a screening test of fetal cells in the maternal blood. Black and Hispanic   In the United States, black people mostly suffer from sickle cell anemia. 1 in 500 live births and Hispanics 1 in 36,000 live births are having this. Also, the people having their ancestors from Saudi, Africa, India, the Caribbean or Central America carry SCD.   Treatment of Sickle cell disease during pregnancy   Early diagnosis and regular checkups are very important for the pregnant mother having this disease. If the sickle cell trait is present in the baby’s father then amniocentesis is needed to check if the baby has the trait or not. If the mother has sickle cell trait then the doctor advises the father to do the prenatal screening. In sickle cell disease, some people need a blood transfusion to replace their abnormal cells with normal cells. but, in the case of pregnant women, it may affect the baby. During pregnancy, the physician does not advise taking hydroxyurea. a lower dose may be recommended. During labor, the doctor gives intravenous uid therapy and oxygen therapy and also regularly checks the fetal signs. 
  • 7. 2 thoughts on “How to deal with sickle cell disease during pregnancy”   Management of SCD Aspirin 100 mg/day Folic acid 5mg/day Vitamin supplementation Routine urine culture Parenteral uid therapy                  0:00 0:00 / 0:00 / 0:00 Related Harlequin ichthyosis ; Role of ABCA12 gene May 3, 2021 In "Pediatric diseases" Symptoms and causes of fetal alcohol syndrome March 7, 2021 In "Pediatric diseases" How to protect your newborn from neonatal jaundice April 22, 2021 In "Pediatric diseases" Symptoms and causes of fetal alcohol syndrome PREVIOUS POST  How to manage the gestational diabetes insipidus NEXT POST  
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