4. Knowing the Difference
How do I know what I am dealing
with?
What are the Signs of Normal
Stress?
What are the Symptoms of a Mental
Illness?
Should I get treatment?
What will people think of me
5. “It’s what you learn
after you know it all
that counts”
Harry Truman
6. Generally speaking….
If anxiety is affecting you or someone
you know, it's important to learn
the difference. In general, anxiety is a
normal reaction to stress. In fact, it
can be a good thing. ... An anxiety
disorder, however, involves intense
and excessive anxiety, along with
other debilitating symptoms.
7. ANXIETY
Everyone will experience anxiety from time to time.
The demands and stress of life may even make
experiencing anxiety more frequent.
Anxiety is a normal reaction to stress. In fact, it can
be a good thing. Anxiety motivates you to
accomplish things, try harder, and it can warn you
when you’re in a dangerous situation. It informs you
to be extra vigilant about your environment.
Is usually the response to a stressor: such as job
stress, family or financial problems, conflict in
relationships, tests, speaking assignments,
excessive responsibilities, etc.
8. The Disorder
An anxiety disorder, however, involves
intense and excessive anxiety, along
with other debilitating symptoms.
Anxious all the time
Can’t necessarily spot a reason
Can’t hardly make it through the day
Small things are overwhelming
Intense and excessive emotional
feelings
9. General Differences
A person without a disorder might be
anxious right before an exam.
Their anxiety is fleeting and short lived.
A person with Generalized Anxiety
Disorder might feel anxious weeks
before the exam.
This person’s anxiety is ongoing and
lasts for weeks or even months.
10. NORMAL STRESS / ANXIETY
Is related to a specific situation or
problem
Lasts only as long as the situation or
problem
Is proportional to the situation or
problem
Is a realistic response to a realistic
problem or situation
11.
12.
13. BURNOUT
Can be debilitating
Usually results in job/role dissatisfaction
Can mimic or trigger an anxiety or mood
disorder
Mostly need attention to self-regulation
May need professional intervention if not
resolving within a few weeks.
14. ANXIETY DISORDER
Comes up unexpectedly, for seemingly no reason
The anxiety response to a situation or problem may
be much stronger that they would expect
They may experience a lot of unrealistic anxiety,
such as fear of a situation that likely will never
happen
Lasts a long time, even when the situation or
problem has been resolved
Feels impossible to control or manage
Avoids situations or things that they believe to
trigger anxiety symptoms
15. ANXIETY SYMPTOMS
Persistent worrying or obsession about small
or large concerns that's out of proportion to
the impact of the event
Inability to set aside or let go of a worry
Inability to relax, restlessness, and feeling
keyed up or on edge
Difficulty concentrating, or the feeling that
your mind "goes blank"
Worrying about excessively worrying
16. ANXIETY – EVEN MORE
Distress about making decisions for fear of
making the wrong decision
Carrying every option in a situation all the
way out to its possible negative conclusion
Difficulty handling uncertainty or
indecisiveness
Physical signs and symptoms
19. A person with GAD might say:
“You feel like you can’t breathe, can’t talk
or have to go to the bathroom frequently.
You feel detached or disconnected from
reality. At times you can’t think straight
and have difficulty concentrating. I have
racing or negative thoughts, and am
unable to concentrate and worry about
day-to-day things. “
20. They might also say:
“When I struggle with anxiety, it affects my
entire life. It impairs or interferes with my
schoolwork, job and daily life. I want to avoid
every one and every thing. It can be quite
debilitating. I want to avoid normal activities. I
want to skip class, miss a test, stop going to
work, procrastinate grocery shopping or avoid
anything that makes me feel anxious.”
23. DEPRESSION (Illness?)
Depression is a medical condition that
can affect a person’s ability to work,
study, interact with people or take
care of themselves.
Everyone feels grief, sadness, or
alone at some point. Normal grief is
situational and typically resolves.
24. DEPRESSION
When sadness becomes too much to
handle, or lingers for a long time, it
may be a sign of depression.
It can be caused by imbalances in
brain chemistry. But it can also be
triggered by stress, poor nutrition,
physical illness, personal loss, and
school or relationship difficulties.
25. DEPRESSION
Not everyone experiences depression in the same
way. Depressed people may appear withdrawn and
despondent, or they may be aggressive and self-
destructive. Some people may be depressed about
a specific problem, while others feel deeply unhappy
without knowing why. Sometimes, a depressed
person may even appear “fine” to their friends and
family. The common thread, however, is an
overwhelming, persistent feeling of despair.
26. DEPRESSION
Persistently sad, anxious, irritable or empty
mood
Loss of interest in previously enjoyable
activities
Withdrawal from friends and family
Trouble sleeping or sleeping too much
Fatigue and decreased energy
Significant change in appetite and/or weight
Overreaction to criticisms
27. DEPRESSION
Feeling unable to meet expectations
Difficulty concentrating, remembering details, and
making decisions
Feelings of worthlessness, hopelessness or guilt
Persistent physical symptoms such as headaches,
digestive problems or chronic pain that do not
respond to routine treatment
Substance abuse problems
Thoughts of suicide or suicide attempts
30. THE SCIENCE
Mood and Anxiety Disorders are
characterized by a variety of neuroendocrine,
neurotransmitter, and neuroanatomical
disruptions.
Complicated by the high degree of
interconnectivity between circuits in the limbic
system, brain stem, and higher cortical brain
areas.
32. THE SCIENCE
Symptoms of mood and anxiety disorders are
a result in part from disruption in the balance
of activity in the emotional centers of the
brain rather than the higher cognitive centers.
Explains why we can’t “think ourselves
better”.
Genetic studies have focused on the activity
of the hypothalamus – pituitary – adrenal axis
(HPA).
33.
34. CORTEX
Executive Functioning such as planning,
decision-making, predicting consequences
for potential behaviors, understanding and
modifying social behaviors.
Orbitofrontal cortex codes information,
controls impulses, and coordinates mood with
Limbic system.
Ventromedial cortex is involved in reward
processing and regulating our response to
emotions.
35.
36. LIMBIC SYSTEM
Well-documented research shows a
significant relationship with neurotransmitters
in this area (Serotonin, Norepinephrine, &
Dopamine) and mood disorders.
PET scans show increased glucose activity
and changes blood flow in this area,
especially during panic attacks.
37.
38. LIMBIC SYSTEM
Amygdala: responsible for emotions, survival
instincts, labido and memory
Hippocampus: responsible for emotional
regulation and long term memory
Thalamus: is involved in sensory and motor
signal relay and the regulation of
consciousness and sleep
39.
40. LIMBIC SYSTEM
Hypothalamus: links the nervous and endocrine
systems by way of the pituitary gland. Its function is
to secrete releasing hormones
and inhibiting hormones that stimulate or inhibit.
Responsible for Homeostasis (bringing balance or to
a set point like a thermostat). Hunger, thirst,
response to pain, levels of pleasure, sexual
satisfaction, anger and aggression, and Autonomic
Nervous System regulation (BP, pulse, breathing,
disgestion, etc.).
41.
42. Example of Malfunction
It is hypothesized that symptoms of PTSD,
including intrusive thoughts and re-
experiencing trauma, result from an inability
of higher cognitive structures to repress
negative emotional memories. This task
requires interrelated executive and emotional
processing systems. Sensory deficits result
from systems being overpowered by
hypervigilance and hyperarousal.
43. NEUROTRANSMITTERS:
Limbic system over-activity in patients
with Generalized Anxiety is from:
Decreased inhibitory
neurotransmitters
Increased excitatory
neurotransmitters
Or a combination of both
44. WOW
The Brain is so complicated
There is so much more:
Glutamate and GABA
Complicated to understand and explain the
pathology and etiology of Mental Illness
Even harder to have an exact science with
medications
Medications and Learning is important
46. PAIN - CAUSED BY 4 THINGS
LOSS
REJECTION
FAILURE
PHYSICAL
47. ANXIETY – WARNING OF PAIN
Anxiety is the emotion that warns us
of an impending hurt or danger
Anxiety can motivate or paralyze
Warning sign to fight or flee
Never pleasant
Designed to protect us
49. TREATMENT FOR ANXIETY
AND DEPRESSION
We can talk about them together or separate
due to the nature of the illness and the similar
pharmaceutical approaches.
Many people have both.
Treatment can be compartmentalized if
necessary based on the diagnosis.
Cognitive Therapy + Medication = greatest
success.
The limbic system is a complex set of structures that lies on both sides of the thalamus, just under the cerebrum. It includes the hypothalamus, the hippocampus, the amygdala, and several other nearby areas. It appears to be primarily responsible for our emotional life, and has a lot to do with the formation of memories.
Amygdala
The amygdalas are two almond-shaped masses of neurons on either side of the thalamus at the lower end of the hippocampus. When it is stimulated electrically, animals respond with aggression. And if the amygdala is removed, animals get very tame and no longer respond to things that would have caused rage before. But there is more to it than just anger: When removed, animals also become indifferent to stimuli that would have otherwise have caused fear and even sexual responses.
In humans – Amygdala – activation = Social Anxiety Disorder.
Kids with GAD – enlarged Amygdala’s – Stress induced amygdalar hypertrophy.
IMPORTANT ROLE IN FEAR RESPONSE!
Hippocampus
The hippocampus consists of two “horns” that curve back from the amygdala. It appears to be very important in converting things that are “in your mind” at the moment (in short-term memory) into things that you will remember for the long run (long-term memory). If the hippocampus is damaged, a person cannot build new memories, and lives instead in a strange world where everything they experience just fades away, even while older memories from the time before the damage are untouched! This very unfortunate situation is fairly accurately portrayed in the wonderful movie Memento, as well as in a more light-hearted movie, 50 First Dates. But there is nothing light-hearted about it: Most people who suffer from this kind of brain damage end up institutionalized.
Hypothalamus
The hypothalamus is a small part of the brain located just below the thalamus on both sides of the third ventricle. (The ventricles are areas within the cerebrum that are filled with cerebrospinal fluid, and connect to the fluid in the spine.) It sits just inside the two tracts of the optic nerve, and just above (and intimately connected with) the pituitary gland.
The hypothalamus is one of the busiest parts of the brain, and is mainly concerned with homeostasis. Homeostasis is the process of returning something to some “set point.” It works like a thermostat: When your room gets too cold, the thermostat conveys that information to the furnace and turns it on. As your room warms up and the temperature gets beyond a certain point, it sends a signal that tells the furnace to turn off.
The hypothalamus is responsible for regulating your hunger, thirst, response to pain, levels of pleasure, sexual satisfaction, anger and aggressive behavior, and more. It also regulates the functioning of the autonomic nervous system (see below), which in turn means it regulates things like pulse, blood pressure, breathing, and arousal in response to emotional circumstances.
The hypothalamus receives inputs from a number of sources. From the vagus nerve, it gets information about blood pressure and the distension of the gut (that is, how full your stomach is). From the reticular formation in the brainstem, it gets information about skin temperature. From the optic nerve, it gets information about light and darkness. From unusual neurons lining the ventricles, it gets information about the contents of the cerebrospinal fluid, including toxins that lead to vomiting. And from the other parts of the limbic system and the olfactory (smell) nerves, it gets information that helps regulate eating and sexuality. The hypothalamus also has some receptors of its own, that provide information about ion balance and temperature of the blood.
In one of the more recent discoveries, it seems that there is a protein called leptin which is released by fat cells when we overeat. The hypothalamus apparently senses the levels of leptin in the bloodstream and responds by decreasing appetite. It would seem that some people have a mutation in a gene which produces leptin, and their bodies can’t tell the hypothalamus that they have had enough to eat. However, many overweight people do not have this mutation, so there is still a lot of research to do!
The hypothalamus sends instructions to the rest of the body in two ways. The first is to the autonomic nervous system. This allows the hypothalamus to have ultimate control of things like blood pressure, heartrate, breathing, digestion, sweating, and all the sympathetic and parasympathetic functions.
The other way the hypothalamus controls things is via the pituitary gland. It is neurally and chemically connected to the pituitary, which in turn pumps hormones called releasing factors into the bloodstream. As you know, the pituitary is the so-called “master gland,” and these hormones are vitally important in regulating growth and metabolism.