![1/2
Volume 1 - Issue - 2
Introduction
The reported incidence of cutaneous spread from primary
urologic malignancies is 1.3%. Urinary bladder malignancies
altogether account for 0.84% of cutaneous metastases [1]. In this
case report, we present a patient with transitional cell carcinoma
bladder who developed a solitary subcutaneous nodular metastasis
in the right gluteal region of two months duration [2].
Case Report
A 60M presented with total recurrent painless gross haematuria
with passage of clots for one year. No history of LUTS. GPE-normal.
LE-tender s/c mass of size 4x3 cm, firm, freely mobile, on the (R)
gluteal region, local tempt normal (Figure 1) [3].
Figure 1: Photograph showing the tender s/c mass of size
4x3cm, firm, freely mobile,on the right gluteal Region.
Results
Figure 2: FNAC of the s/c mass-micro photograph showing the
infiltration of the skin by the metastatic TCC.
Cystoscopy done a papillary growth of approximately of size
4x3cm in the right posterolateral wall and trigone close to bladder
neck. No changes suggestive of carcinoma in situ on cystoscopy.
TURBT was done. Biopsy-low grade papillary urothelial carcinoma
(lamina invasive) [4]. FNAC (fine needle aspiration cytology) of
the subcutaneous nodule was strongly suggestive of metastatic
deposits of urothelial carcinoma. C.T urography showed metastatic
bony lesions in the spine. The patient was referred to radiotherapy
department for further treatment (Figure 2).
Conclusion
This is a rare case of early presentation of cutaneous metastasis
of transitional cell carcinoma particularly of low grade type. In
many cases, as in our patient, treatment is mainly supportive and
prognosis is poor (Figure 3) [5]. Therefore, it is important for
the medical community to have access to each case, through case
reports, so as to advance our understanding of this particular
disease.
Figure 3: Cold biopsy from bladder growth-microphotograph
showing low grade papillary urothelial carcinoma (lamina
invasive).
References
1. Mueller TJ, Wu H, Greenberg RE, Hudes G, Topham N, et al. (2004)
Cutaneous metastases from genitourinary malignancies. Urology 63(6):
1021-1026.
2. Fujita K, Sakamoto Y, Fujime M, Kitagawa R (1994) Two cases of
inflammatory skin metastasis from transitional cell carcinoma of the
urinary bladder. Urol Int 53(2): 114-116.
Vazir Singh Rathee*, Sartaj Wali Khan, Aditya Kumar, Shukla PK, Trivedi S and Dwivedi US
Department of Urology, BHU, India
*Corresponding author: Vazir Singh Rathee, Department of Urology, IMS, BHU, Varanasi, UP, India, Tel: 9416380676; Email:
Submission: September 10, 2017; Published: January 11, 2018
Cutaneous Metastasis of Transitional Cell Carcinoma
of Urinary Bladder-An Unusual Case
Exp Tech Urol Nephrol
Copyright © All rights are reserved by Vazir Singh Rathee.
CRIMSONpublishers
http://www.crimsonpublishers.com
Case Report
ISSN 2578-0395](https://image.slidesharecdn.com/etun-181212103521/85/Cutaneous-Metastasis-of-Transitional-Cell-Carcinoma-of-Urinary-Bladder-An-Unusual-Case_Crimson-Publishers-1-320.jpg)
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Cutaneous Metastasis of Transitional Cell Carcinoma of Urinary Bladder-An Unusual Case_Crimson Publishers
- 1. 1/2 Volume 1 - Issue - 2 Introduction The reported incidence of cutaneous spread from primary urologic malignancies is 1.3%. Urinary bladder malignancies altogether account for 0.84% of cutaneous metastases [1]. In this case report, we present a patient with transitional cell carcinoma bladder who developed a solitary subcutaneous nodular metastasis in the right gluteal region of two months duration [2]. Case Report A 60M presented with total recurrent painless gross haematuria with passage of clots for one year. No history of LUTS. GPE-normal. LE-tender s/c mass of size 4x3 cm, firm, freely mobile, on the (R) gluteal region, local tempt normal (Figure 1) [3]. Figure 1: Photograph showing the tender s/c mass of size 4x3cm, firm, freely mobile,on the right gluteal Region. Results Figure 2: FNAC of the s/c mass-micro photograph showing the infiltration of the skin by the metastatic TCC. Cystoscopy done a papillary growth of approximately of size 4x3cm in the right posterolateral wall and trigone close to bladder neck. No changes suggestive of carcinoma in situ on cystoscopy. TURBT was done. Biopsy-low grade papillary urothelial carcinoma (lamina invasive) [4]. FNAC (fine needle aspiration cytology) of the subcutaneous nodule was strongly suggestive of metastatic deposits of urothelial carcinoma. C.T urography showed metastatic bony lesions in the spine. The patient was referred to radiotherapy department for further treatment (Figure 2). Conclusion This is a rare case of early presentation of cutaneous metastasis of transitional cell carcinoma particularly of low grade type. In many cases, as in our patient, treatment is mainly supportive and prognosis is poor (Figure 3) [5]. Therefore, it is important for the medical community to have access to each case, through case reports, so as to advance our understanding of this particular disease. Figure 3: Cold biopsy from bladder growth-microphotograph showing low grade papillary urothelial carcinoma (lamina invasive). References 1. Mueller TJ, Wu H, Greenberg RE, Hudes G, Topham N, et al. (2004) Cutaneous metastases from genitourinary malignancies. Urology 63(6): 1021-1026. 2. Fujita K, Sakamoto Y, Fujime M, Kitagawa R (1994) Two cases of inflammatory skin metastasis from transitional cell carcinoma of the urinary bladder. Urol Int 53(2): 114-116. Vazir Singh Rathee*, Sartaj Wali Khan, Aditya Kumar, Shukla PK, Trivedi S and Dwivedi US Department of Urology, BHU, India *Corresponding author: Vazir Singh Rathee, Department of Urology, IMS, BHU, Varanasi, UP, India, Tel: 9416380676; Email: Submission: September 10, 2017; Published: January 11, 2018 Cutaneous Metastasis of Transitional Cell Carcinoma of Urinary Bladder-An Unusual Case Exp Tech Urol Nephrol Copyright © All rights are reserved by Vazir Singh Rathee. CRIMSONpublishers http://www.crimsonpublishers.com Case Report ISSN 2578-0395
- 2. Experimental Techniques in Urology & Nephrology 2/2 Exp Tech Urol Nephrol How to cite this article: Vazir S R, Sartaj W K, Aditya K, Shukla P, Trivedi S, Dwivedi U. Cutaneous Metastasis of Transitional Cell Carcinoma of Urinary Bladder- An Unusual Case. Exp Tech Urol Nephrol. 1(2). ETUN.000509. 2018. DOI: 10.31031/ETUN.2018.01.000509 Volume 1 - Issue - 2 3. Messing EM, Catalona W (1998) Urothelial tumors of the urinary tract. Bladder cancer. In: Walsh PC, Retik AB, Vaughan ED, et al. (Eds.), Campbell′s Urology. (7th edn), W.B. Saunders Co, Philadelphia, USA, pp. 2329-2383. 4. Swick BL, Gordon JR (2010) Superficially invasive transitional cell carcinoma of the bladder associated with distant cutaneous metastases. J Cutan Pathol 37(12): 1245-1250. 5. Block CA, Dahmoush L, Konety BR (2006) Cutaneous metastases from transitional cell carcinoma of the bladder. Urology 67(4): 846.