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Copyright © 2012 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Chapter 9
Quantitative Research Design
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Question
Tell whether the following statement is true or false:
Many qualitative nursing studies aim to elucidate cause-and-
effect relationships.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Answer
False
Many quantitative not qualitative nursing studies aim to
elucidate cause-and-effect relationships.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Question
Tell whether the following statement is true or false:
Counterfactual is what would have happened to the same people
simultaneously exposed and not exposed to the causal factor.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Answer
True
Counterfactual is what would have happened to the same people
simultaneously exposed and not exposed to the causal factor.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
The Counterfactual MethodThe counterfactual is what would
have happened to the same people simultaneously exposed and
not exposed to the causal factor.Effect represents the difference
between the two.
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
CausalityThe counterfactual methodCriteria for causality—
Lazarsfeld (1955)
1. Temporal
2. Empirical relationship
3. Relationship cannot be explained as
being caused by a third variable
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Experiments or Randomized Controlled Trial Properties
Manipulation
Control
Randomization
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
ManipulationDoing something to study
participantsExperimenter manipulates the independent variable
by administering a treatment (intervention) to some subjects and
withholding it from others, or by administering some other
treatment.
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Control GroupResearchers can expose the control group to
various conditions:
– No treatment
– Alternative treatment
– Placebo
– Standard treatment
– Different doses of the treatment
– Wait list
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Randomization (Random Assignment or Random
Allocation)Involves placing subjects into treatment conditions
at randomApproximates the ideal—but impossible—
counterfactual of having the same people in multiple treatment
groups simultaneouslyBasic randomization
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Question
Tell whether the following statement is true or false:
Some studies involve patient-centered interventions that are
tailored to meet individual needs or characteristics.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Answer
True
Everyone in the experimental group usually gets the same
intervention as delineated in formal protocols, but some studies
involve patient-centered interventions (PCIs) that are tailored to
meet individual needs or characteristics.
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Small Table of Random Digits
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Example of Random Assignment Procedure
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
StratificationDivided into groups before randomizedPermuted
block randomization
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
BlindingSingle-blind studiesDouble-blind studies
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
RandomizationClusterPartially randomized patient preference
designRandomized consent design
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Experimental DesignsAfter-only (posttest-only) designBefore–
after (pretest–posttest) designFactorial designCrossover
(repeated measures) design
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Symbolic Representation of a Pretest–Posttest Experimental
Design
R O1 X O2
R O1 O2
R = Randomization
O = An observation or measurement
X = An intervention
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Factorial DesignsTwo or more variables are manipulated
simultaneously.Test both main effects and interaction
effectsRandomized block designCrossover design
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Quasi-Experimental and
Preexperimental Designs
Nonequivalent control group pretest–posttest design (quasi-
experimental)
O1 X O2
O1 O2
Nonequivalent control group posttest-only design
(preexperimental)
X O1
O1
One group pretest-posttest design (preexperimental)
O1 X O2
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Quasi-Experimental Designs
Time series designNonequivalent control group
before–after
design
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Time Series Design
O1 O2 O3 O4 X O5 O6 O7 O8
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Other Quasi-Experimental DesignsQuasi-experimental dose-
response analysisQuasi-experimental (nonrandomized) arms of a
PRPP randomization design
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Nonexperimental/Observational ResearchDescriptive
researchCorrelational studies
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Designs of Correlational StudiesRetrospective (case-control)
designProspective (cohort) designsNatural experimentsPath
analytic studies
*
Copyright © 2017 Wolters Kluwer Health | Lippincott Williams
& Wilkins
Descriptive StudiesPrevalence studiesIncidence studies
*
Copyright © 2012 Wolters Kluwer Health  Lippincott Williams

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Copyright © 2012 Wolters Kluwer Health Lippincott Williams

  • 1. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 9 Quantitative Research Design * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Tell whether the following statement is true or false: Many qualitative nursing studies aim to elucidate cause-and- effect relationships. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer False
  • 2. Many quantitative not qualitative nursing studies aim to elucidate cause-and-effect relationships. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Tell whether the following statement is true or false: Counterfactual is what would have happened to the same people simultaneously exposed and not exposed to the causal factor. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer True Counterfactual is what would have happened to the same people simultaneously exposed and not exposed to the causal factor. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins The Counterfactual MethodThe counterfactual is what would have happened to the same people simultaneously exposed and not exposed to the causal factor.Effect represents the difference between the two. *
  • 3. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins CausalityThe counterfactual methodCriteria for causality— Lazarsfeld (1955) 1. Temporal 2. Empirical relationship 3. Relationship cannot be explained as being caused by a third variable * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Experiments or Randomized Controlled Trial Properties Manipulation Control Randomization * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins ManipulationDoing something to study
  • 4. participantsExperimenter manipulates the independent variable by administering a treatment (intervention) to some subjects and withholding it from others, or by administering some other treatment. * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Control GroupResearchers can expose the control group to various conditions: – No treatment – Alternative treatment – Placebo – Standard treatment – Different doses of the treatment – Wait list * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Randomization (Random Assignment or Random Allocation)Involves placing subjects into treatment conditions at randomApproximates the ideal—but impossible— counterfactual of having the same people in multiple treatment groups simultaneouslyBasic randomization
  • 5. * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Tell whether the following statement is true or false: Some studies involve patient-centered interventions that are tailored to meet individual needs or characteristics. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer True Everyone in the experimental group usually gets the same intervention as delineated in formal protocols, but some studies involve patient-centered interventions (PCIs) that are tailored to meet individual needs or characteristics. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Small Table of Random Digits Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Example of Random Assignment Procedure
  • 6. Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins StratificationDivided into groups before randomizedPermuted block randomization Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins BlindingSingle-blind studiesDouble-blind studies Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins RandomizationClusterPartially randomized patient preference designRandomized consent design Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Experimental DesignsAfter-only (posttest-only) designBefore– after (pretest–posttest) designFactorial designCrossover (repeated measures) design * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 7. Symbolic Representation of a Pretest–Posttest Experimental Design R O1 X O2 R O1 O2 R = Randomization O = An observation or measurement X = An intervention * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Factorial DesignsTwo or more variables are manipulated simultaneously.Test both main effects and interaction effectsRandomized block designCrossover design * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Quasi-Experimental and Preexperimental Designs
  • 8. Nonequivalent control group pretest–posttest design (quasi- experimental) O1 X O2 O1 O2 Nonequivalent control group posttest-only design (preexperimental) X O1 O1 One group pretest-posttest design (preexperimental) O1 X O2 * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 9. Quasi-Experimental Designs Time series designNonequivalent control group before–after design * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Time Series Design O1 O2 O3 O4 X O5 O6 O7 O8 * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Other Quasi-Experimental DesignsQuasi-experimental dose- response analysisQuasi-experimental (nonrandomized) arms of a PRPP randomization design
  • 10. * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Nonexperimental/Observational ResearchDescriptive researchCorrelational studies * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Designs of Correlational StudiesRetrospective (case-control) designProspective (cohort) designsNatural experimentsPath analytic studies * Copyright © 2017 Wolters Kluwer Health | Lippincott Williams & Wilkins Descriptive StudiesPrevalence studiesIncidence studies *