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© The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14
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Am I Blue:Am I Blue:
Cardiac ClassificationsCardiac Classifications
Lori Erickson MSN, CPNP
The Ward Family Heart Center
Children’s Mercy Hospital
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DisclosureDisclosure
 No financial disclosures
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ObjectivesObjectives
 Identify the Neonate with potential
cardiac v. respiratory problem
 Discuss babies prenatally diagnosed
and how to manage at delivery
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OutlineOutline
 Overview of fetal physiology
 Review of Neonatal heart disease
including
– Physiology
– Clinical presentation
 Cardiac Delivery Classification for
prenatal diagnosis
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BackgroundBackground
 Early Diagnosis
 Prenatal
 Postnatal
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Fetal
Physiolog
y
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Birth ChangesBirth Changes
 Lungs expand, 02
increased
 Pulmonary vascular
resistance drops
 Pulmonary venous
return increases
 Ductus arteriosus flow
reverses
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What fetal structure is kept open with
the medication prostaglandin (PGE)?
A.A. Patent ForamenPatent Foramen
OvaleOvale
B.B. DuctusDuctus
ArteriosusArteriosus
C.C. Ductus VenosusDuctus Venosus
D.D. VentricularVentricular
Septal DefectSeptal Defect
PatentForam
en
OvaleDuctusArteriosus
DuctusVenosus
VentricularSeptalDefect
0% 0%0%0%
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Congenital Heart DiseaseCongenital Heart Disease
(CHD)(CHD)
 Electrical
– Arrhythmia
 Plumbing
– Blockage with any of the 4 valves have stenosis
or atresia
– Great vessels not hooked up correctly
– Holes in heart
 Function
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CHD OverviewCHD Overview
 Goals of CHD evaluation
– Early recognition of disease
– Knowledge of physiology
– Resuscitation and stabilization
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Delivery ClassificationDelivery Classification
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 Baby
 Mother
 Father
 Neonatologist
 Cardiologist
 RN1
 RN2
 RT
 ECHO tech
 Neo 2
 NNP
 Cath Doc
 Cardiac Surgeon
 3 CV nurses
 2 cath nurses
 Fetal Cardiac APRN
 Fetal Cardiac RN
 CV Perfusion (4)
 Cardiac Anesthesia
 OB team….
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Fetal ECHO’sFetal ECHO’s
 Only primary cardiac
diagnosis
 See another 100 patients
with multiple conditions
 70% delivered at CMH
 60% of Class I delivered
elsewhere
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PreparationPreparation
 High risk, low
frequency cases
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Class IClass I
 Stable
Hemodynamics
anticipated
 Non-Ductal
dependent
 Examples:
 CAVC
 Truncus
arteriosus
 TOF
 VSD
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Class I: BehaversClass I: Behavers
 Normal NRP
assessment and
evaluation
 Monitor for adequate
pulmonary and
systemic blood flow
 Echo after birth when
able
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Tetralogy of Fallot (TOF)
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Class I ExpectationsClass I Expectations
 Cardiology consult after birth
 Follow-up in outpatient clinic
 No neonatal surgery planned (first 30 days of
life- may need it later)
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Class II: Neonatal surgeryClass II: Neonatal surgery
 Stable
Hemodynamics
anticipated
 Ductal dependent
lesions
 Examples:
 HLHS
 Single ventricle
with atresia
 COA
 Hypoplastic
aortic arch
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Hypoplastic Left Heart Syndrome
(HLHS)
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Class II: Expectations
 Single ventricleSingle ventricle
hemodynamicshemodynamics
 Most require PGEMost require PGE
infusioninfusion
 Pulmonary flowPulmonary flow
 Systemic flowSystemic flow
 Surgery 1Surgery 1stst
1-2 weeks1-2 weeks
of life if termof life if term
 Umbilical linesUmbilical lines
 Side effects of PGESide effects of PGE
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Class II EvaluationClass II Evaluation
 Pulse oximetry
– Sat 75-85%
– Location of desaturation
 Ventilation
 ABG
– Possible Low pO2
– No significant metabolic acidosis unless
profoundly cyanotic or low cardiac output
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Class II MisbehavingClass II Misbehaving
 Not acting right?
– NRP
– Evaluate hemodynamics
– Mixing appropriately
– Output getting to systemic and pulmonary
blood flow
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Class III: Expecting badnessClass III: Expecting badness
 Possible
Hemodynamic
instability
 Examples:
 d-TGA
 TAPVR
 Heart Block
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Class III ExpectationsClass III Expectations
 Cardiology in house for
echo
 Ready for inotropic
support, airway support
 Communication early-
Troops on stand-by
 Cardiac cath on hold
 CV surgery on hold
HELP!
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Clinical PresentationClinical Presentation
 Cyanotic right from birth- 50-60’s
 Severe respiratory distress
 Weak to normal pulses
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Class IIIClass III
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What do you think this above case is most
likely? Cardiology isn’t available yet- stuck
in traffic coming to your hospital
A.A. MeconiumMeconium
AspirationAspiration
B.B. PulmonaryPulmonary
HypertensionHypertension
C.C. Total AnomalousTotal Anomalous
PulmonaryPulmonary
venous returnvenous return
D.D. Severe bilateralSevere bilateral
pneumoniapneumonia
M
econium
Aspiration
Pulm
onary
Hypertension
TotalAnom
alousPulm
ona..
Severe
bilateralpneum
onia
0% 0%0%0%
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TAPVR
 InfradiaphragmaticInfradiaphragmatic
TAPVRTAPVR
 Pulmonary veinsPulmonary veins
return to confluencereturn to confluence
that drains downthat drains down
below thebelow the
diaphragm anddiaphragm and
enters inferior venaenters inferior vena
cavacava
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Class IV: CalvaryClass IV: Calvary
 Hemodynamic
Instability expected
at separation from
placental
circulation
 Examples:
 HLHS with
restrictive atrial
septum
 d-TGA with
restrictive atrial
septum
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D-tga with RAS
 Survival depends onSurvival depends on
mixing of blue and redmixing of blue and red
bloodblood
 ImmediateImmediate
septostomyseptostomy
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Class IV ExpectationsClass IV Expectations
 Everything for class III PLUS delivery in
cardiac OR
 Cardiac Anesthesia in delivery
 LIFE SAVING
 Only getting them stable to get to the
first surgery
 Long road ahead
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Is it Heart?Is it Heart?
 Extremely varied presentation
 As pulmonary vascular resistance drops
– Pulmonary blood flow will increase
– Saturations will increase
– Pulmonary over-circulation may result in heart
failure (tachypnea, grunting, retractions,
tachycardia)
 Generally not distressed until develop heart
failure (gradual)
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Likely Heart DiseaseLikely Heart Disease
 Massive cardiomegaly with poor
cardiac output, gallop and/or murmur
 Obvious dysrhythmia
– Bradycardia
– Extreme tachycardia
– Non-perfusing rhythm
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Possible Heart DiseasePossible Heart Disease
 Respiratory distress and cyanosis
– Most often pulmonary/infectious etiology
– May be cardiac (or combination)
– Chest x-ray may or may not be helpful in
distinguishing between etiologies
– Support as needed and early transfer to
tertiary care center for evaluation and
management
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What cardiac delivery
classification is a HLHS with
no ASD restriction?
A.A. Class IClass I
B.B. Class IIClass II
C.C. Class IIIClass III
D.D. Class IVClass IV
E.E. What’s a deliveryWhat’s a delivery
classification?classification?
ClassI
ClassII
ClassIII
ClassIV
W
hat’sa
deliveryclassifi...
0% 0% 0%0%0%
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Final thoughtsFinal thoughts
 High Risk, low frequency
 Life saving interventions
 Delivery with CMH only if have to!
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I Am Blue: Cardiac Classifications

  • 1. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 1 © The Children's Mercy Hospital, 2014. 08/14 1 © The Children's Mercy Hospital, 2014. 03/14 Am I Blue:Am I Blue: Cardiac ClassificationsCardiac Classifications Lori Erickson MSN, CPNP The Ward Family Heart Center Children’s Mercy Hospital
  • 2. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 2 © The Children's Mercy Hospital, 2014. 08/14 2 © The Children's Mercy Hospital, 2014. 03/14 DisclosureDisclosure  No financial disclosures
  • 3. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 3 © The Children's Mercy Hospital, 2014. 08/14 3 © The Children's Mercy Hospital, 2014. 03/14 ObjectivesObjectives  Identify the Neonate with potential cardiac v. respiratory problem  Discuss babies prenatally diagnosed and how to manage at delivery
  • 4. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 4 © The Children's Mercy Hospital, 2014. 08/14 4 © The Children's Mercy Hospital, 2014. 03/14 OutlineOutline  Overview of fetal physiology  Review of Neonatal heart disease including – Physiology – Clinical presentation  Cardiac Delivery Classification for prenatal diagnosis
  • 5. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 5 © The Children's Mercy Hospital, 2014. 08/14 5 © The Children's Mercy Hospital, 2014. 03/14 BackgroundBackground  Early Diagnosis  Prenatal  Postnatal
  • 6. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 6 © The Children's Mercy Hospital, 2014. 08/14 Fetal Physiolog y
  • 7. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 7 © The Children's Mercy Hospital, 2014. 08/14 7 © The Children's Mercy Hospital, 2014. 03/14 Birth ChangesBirth Changes  Lungs expand, 02 increased  Pulmonary vascular resistance drops  Pulmonary venous return increases  Ductus arteriosus flow reverses
  • 8. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 8 © The Children's Mercy Hospital, 2014. 08/14 What fetal structure is kept open with the medication prostaglandin (PGE)? A.A. Patent ForamenPatent Foramen OvaleOvale B.B. DuctusDuctus ArteriosusArteriosus C.C. Ductus VenosusDuctus Venosus D.D. VentricularVentricular Septal DefectSeptal Defect PatentForam en OvaleDuctusArteriosus DuctusVenosus VentricularSeptalDefect 0% 0%0%0%
  • 9. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 9 © The Children's Mercy Hospital, 2014. 08/14 9 © The Children's Mercy Hospital, 2014. 03/14 Congenital Heart DiseaseCongenital Heart Disease (CHD)(CHD)  Electrical – Arrhythmia  Plumbing – Blockage with any of the 4 valves have stenosis or atresia – Great vessels not hooked up correctly – Holes in heart  Function
  • 10. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 10 © The Children's Mercy Hospital, 2014. 08/14 10 © The Children's Mercy Hospital, 2014. 03/14 CHD OverviewCHD Overview  Goals of CHD evaluation – Early recognition of disease – Knowledge of physiology – Resuscitation and stabilization
  • 11. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 11 © The Children's Mercy Hospital, 2014. 08/14 11 © The Children's Mercy Hospital, 2014. 03/14 Delivery ClassificationDelivery Classification
  • 12. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 12 © The Children's Mercy Hospital, 2014. 08/14 12 © The Children's Mercy Hospital, 2014. 03/14
  • 13. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 13 © The Children's Mercy Hospital, 2014. 08/14 13 © The Children's Mercy Hospital, 2014. 03/14
  • 14. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 14 © The Children's Mercy Hospital, 2014. 08/14 14 © The Children's Mercy Hospital, 2014. 03/14  Baby  Mother  Father  Neonatologist  Cardiologist  RN1  RN2  RT  ECHO tech  Neo 2  NNP  Cath Doc  Cardiac Surgeon  3 CV nurses  2 cath nurses  Fetal Cardiac APRN  Fetal Cardiac RN  CV Perfusion (4)  Cardiac Anesthesia  OB team….
  • 15. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 15 © The Children's Mercy Hospital, 2014. 08/14 15 © The Children's Mercy Hospital, 2014. 03/14 Fetal ECHO’sFetal ECHO’s  Only primary cardiac diagnosis  See another 100 patients with multiple conditions  70% delivered at CMH  60% of Class I delivered elsewhere
  • 16. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 16 © The Children's Mercy Hospital, 2014. 08/14 16 © The Children's Mercy Hospital, 2014. 03/14 PreparationPreparation  High risk, low frequency cases
  • 17. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 17 © The Children's Mercy Hospital, 2014. 08/14 17 © The Children's Mercy Hospital, 2014. 03/14 Class IClass I  Stable Hemodynamics anticipated  Non-Ductal dependent  Examples:  CAVC  Truncus arteriosus  TOF  VSD
  • 18. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 18 © The Children's Mercy Hospital, 2014. 08/14 18 © The Children's Mercy Hospital, 2014. 03/14 Class I: BehaversClass I: Behavers  Normal NRP assessment and evaluation  Monitor for adequate pulmonary and systemic blood flow  Echo after birth when able
  • 19. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 19 © The Children's Mercy Hospital, 2014. 08/14 Tetralogy of Fallot (TOF)
  • 20. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 20 © The Children's Mercy Hospital, 2014. 08/14 20 © The Children's Mercy Hospital, 2014. 03/14 Class I ExpectationsClass I Expectations  Cardiology consult after birth  Follow-up in outpatient clinic  No neonatal surgery planned (first 30 days of life- may need it later)
  • 21. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 21 © The Children's Mercy Hospital, 2014. 08/14 21 © The Children's Mercy Hospital, 2014. 03/14 Class II: Neonatal surgeryClass II: Neonatal surgery  Stable Hemodynamics anticipated  Ductal dependent lesions  Examples:  HLHS  Single ventricle with atresia  COA  Hypoplastic aortic arch
  • 22. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 22 © The Children's Mercy Hospital, 2014. 08/14 Hypoplastic Left Heart Syndrome (HLHS)
  • 23. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 23 © The Children's Mercy Hospital, 2014. 08/14 Class II: Expectations  Single ventricleSingle ventricle hemodynamicshemodynamics  Most require PGEMost require PGE infusioninfusion  Pulmonary flowPulmonary flow  Systemic flowSystemic flow  Surgery 1Surgery 1stst 1-2 weeks1-2 weeks of life if termof life if term  Umbilical linesUmbilical lines  Side effects of PGESide effects of PGE
  • 24. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 24 © The Children's Mercy Hospital, 2014. 08/14 24 © The Children's Mercy Hospital, 2014. 03/14 Class II EvaluationClass II Evaluation  Pulse oximetry – Sat 75-85% – Location of desaturation  Ventilation  ABG – Possible Low pO2 – No significant metabolic acidosis unless profoundly cyanotic or low cardiac output
  • 25. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 25 © The Children's Mercy Hospital, 2014. 08/14 25 © The Children's Mercy Hospital, 2014. 03/14 Class II MisbehavingClass II Misbehaving  Not acting right? – NRP – Evaluate hemodynamics – Mixing appropriately – Output getting to systemic and pulmonary blood flow
  • 26. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 26 © The Children's Mercy Hospital, 2014. 08/14 26 © The Children's Mercy Hospital, 2014. 03/14 Class III: Expecting badnessClass III: Expecting badness  Possible Hemodynamic instability  Examples:  d-TGA  TAPVR  Heart Block
  • 27. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 27 © The Children's Mercy Hospital, 2014. 08/14 27 © The Children's Mercy Hospital, 2014. 03/14 Class III ExpectationsClass III Expectations  Cardiology in house for echo  Ready for inotropic support, airway support  Communication early- Troops on stand-by  Cardiac cath on hold  CV surgery on hold HELP!
  • 28. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 28 © The Children's Mercy Hospital, 2014. 08/14 28 © The Children's Mercy Hospital, 2014. 03/14 Clinical PresentationClinical Presentation  Cyanotic right from birth- 50-60’s  Severe respiratory distress  Weak to normal pulses
  • 29. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 29 © The Children's Mercy Hospital, 2014. 08/14 29 © The Children's Mercy Hospital, 2014. 03/14 Class IIIClass III
  • 30. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 30 © The Children's Mercy Hospital, 2014. 08/14 What do you think this above case is most likely? Cardiology isn’t available yet- stuck in traffic coming to your hospital A.A. MeconiumMeconium AspirationAspiration B.B. PulmonaryPulmonary HypertensionHypertension C.C. Total AnomalousTotal Anomalous PulmonaryPulmonary venous returnvenous return D.D. Severe bilateralSevere bilateral pneumoniapneumonia M econium Aspiration Pulm onary Hypertension TotalAnom alousPulm ona.. Severe bilateralpneum onia 0% 0%0%0%
  • 31. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 31 © The Children's Mercy Hospital, 2014. 08/14 TAPVR  InfradiaphragmaticInfradiaphragmatic TAPVRTAPVR  Pulmonary veinsPulmonary veins return to confluencereturn to confluence that drains downthat drains down below thebelow the diaphragm anddiaphragm and enters inferior venaenters inferior vena cavacava
  • 32. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 32 © The Children's Mercy Hospital, 2014. 08/14 32 © The Children's Mercy Hospital, 2014. 03/14 Class IV: CalvaryClass IV: Calvary  Hemodynamic Instability expected at separation from placental circulation  Examples:  HLHS with restrictive atrial septum  d-TGA with restrictive atrial septum
  • 33. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 33 © The Children's Mercy Hospital, 2014. 08/14 33 © The Children's Mercy Hospital, 2014. 03/14
  • 34. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 34 © The Children's Mercy Hospital, 2014. 08/14 34 © The Children's Mercy Hospital, 2014. 03/14
  • 35. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 35 © The Children's Mercy Hospital, 2014. 08/14 D-tga with RAS  Survival depends onSurvival depends on mixing of blue and redmixing of blue and red bloodblood  ImmediateImmediate septostomyseptostomy
  • 36. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 36 © The Children's Mercy Hospital, 2014. 08/14 36 © The Children's Mercy Hospital, 2014. 03/14 Class IV ExpectationsClass IV Expectations  Everything for class III PLUS delivery in cardiac OR  Cardiac Anesthesia in delivery  LIFE SAVING  Only getting them stable to get to the first surgery  Long road ahead
  • 37. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 37 © The Children's Mercy Hospital, 2014. 08/14 37 © The Children's Mercy Hospital, 2014. 03/14 Is it Heart?Is it Heart?  Extremely varied presentation  As pulmonary vascular resistance drops – Pulmonary blood flow will increase – Saturations will increase – Pulmonary over-circulation may result in heart failure (tachypnea, grunting, retractions, tachycardia)  Generally not distressed until develop heart failure (gradual)
  • 38. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 38 © The Children's Mercy Hospital, 2014. 08/14 38 © The Children's Mercy Hospital, 2014. 03/14 Likely Heart DiseaseLikely Heart Disease  Massive cardiomegaly with poor cardiac output, gallop and/or murmur  Obvious dysrhythmia – Bradycardia – Extreme tachycardia – Non-perfusing rhythm
  • 39. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 39 © The Children's Mercy Hospital, 2014. 08/14 39 © The Children's Mercy Hospital, 2014. 03/14 Possible Heart DiseasePossible Heart Disease  Respiratory distress and cyanosis – Most often pulmonary/infectious etiology – May be cardiac (or combination) – Chest x-ray may or may not be helpful in distinguishing between etiologies – Support as needed and early transfer to tertiary care center for evaluation and management
  • 40. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 40 © The Children's Mercy Hospital, 2014. 08/14 What cardiac delivery classification is a HLHS with no ASD restriction? A.A. Class IClass I B.B. Class IIClass II C.C. Class IIIClass III D.D. Class IVClass IV E.E. What’s a deliveryWhat’s a delivery classification?classification? ClassI ClassII ClassIII ClassIV W hat’sa deliveryclassifi... 0% 0% 0%0%0%
  • 41. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 41 © The Children's Mercy Hospital, 2014. 08/14 41 © The Children's Mercy Hospital, 2014. 03/14 Final thoughtsFinal thoughts  High Risk, low frequency  Life saving interventions  Delivery with CMH only if have to!
  • 42. © The Children's Mercy Hospital, 2014. 03/14© The Children's Mercy Hospital, 2014. 03/14 42 © The Children's Mercy Hospital, 2014. 08/14 42 © The Children's Mercy Hospital, 2014. 03/14

Editor's Notes

  1. Early diagnosis through clinical assessment and diagnostic evaluation Preliminary Diagnosis through BP’s, oxygen saturation, hyperoxia test, pulse examination Bedside RN first line during periods of Watch and Wait (ie- questions about arch but holding off on PGE administration to see if PDA declares it is necessary for systemic flow) Early detection and intervention prior to episodes of extremis important for long-term outcome
  2. Normal fetal circulation Ductus venosus: highly oxygenated blood to inferior vena cava across foramen ovale to left atrium Ductus arteriosus: majority of right ventricular output directed to descending aorta Most highly oxygenated blood to brain (saturation 65%) Very little blood flow to lungs (10% combined ventricular output) Lowest oxygen-saturated blood returning from superior vena cava directed to lower half of body to return to placenta
  3. With first breath lungs expand and pulmonary vascular resistance drops All of right ventricular output enters pulmonary circulation Increase in pulmonary venous return increases left atrial pressure and closes flap of foramen ovale Direction of flow across ductus arteriosus reverses (aorta  pulmonary artery) Ductus arteriosus and ductus venosus begin to constrict Once the baby takes the first breath, a number of changes occur in the infant's lungs and circulatory system: Increased oxygen in the lungs causes a decrease in blood flow resistance to the lungs. Blood flow resistance of the baby's blood vessels also increases. Amniotic fluid drains or is absorbed from the respiratory system. The lungs inflate and begin working on their own, moving oxygen into the bloodstream and removing carbon dioxide by breathing out (exhalation).
  4. Plumbing- blockage valve stenosis or atresia Plumbing- hook-up issue Electrical- arrhythmia Function- poor Ductal-dependent systemic blood flow Ductal-dependent pulmonary blood flow Ductal-dependent mixing Obstructed pulmonary venous return Arrhythmias Other
  5. – directs assessment and diagnostic Focus on physiology Exact anatomy will be sorted out after stabilization valuation
  6. Communication Organization
  7. Class I- 48 Class II- 32 Class III- 14 Class IV-3
  8. Other lesions without ductal-dependent systemic or pulmonary blood flow Mixing of oxygenated and deoxygenated blood results in systemic saturations <95% Not generally acutely ill, but may develop pulmonary overcirculation as pulmonary vascular resistance drops
  9. Severe pulmonary valve stenosis including severe tetralogy of Fallot Other complex malformations that include pulmonary valve atresia Often component of heterotaxy syndrome
  10. Small left atrium, mitral valve, left ventricle ascending aorta and aortic arch Lower half of body perfused through PDA Brain and coronary arteries perfused through PDA and retrograde flow in aortic arch
  11. Pulmonary valve atresia All blood flow to lungs supplied through PDA Obligatory right-to-left shunting at atrial level: mild systemic desaturation (80s) Hypoplastic right heart syndrome Small tricuspid valve, right ventricle and pulmonary valve
  12. May look normal while PDA open Pulse oximetry in foot will often be <95% Poor systemic cardiac output when PDA closes (usually within 1st 2 weeks of life) Grey, mottled color Weak or absent pulses May not have pulse differential in coarctation of the aorta in the presence of poor cardiac output May or may not have murmur Tachypnea, grunting, respiratory distress Similar appearance to sepsis Cyanosis Usually no significant respiratory distress Good pulses and capillary refill +/- murmur Loud murmur means there is some pulmonary blood flow (pulmonary stenosis) Absent murmur much more concerning for pulmonary atresia
  13. Similar clinical appearance to meconium aspiration or severe bilateral pneumonia
  14. Communication Organization
  15. Transposition of the great arteries Aorta originates from right ventricle and carries desaturated blood back to body Pulmonary artery originates from left ventricle and carries red blood back to lungs Pulse oximetry: desaturated everywhere, possible higher saturations in feet Chest x-ray: Normal to slightly wet lung fields No cardiomegaly “Egg on a string” ABG: Low pO2 No significant metabolic acidosis unless profoundly cyanotic
  16. In general with complete intracardiac mixing and no outflow tract obstruction saturations will be mid-80s initially.