Report #13-006
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Report #13-006

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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STUDY SCOPE

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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n STUDY...
REPORT HIGHLIGHTS

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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REPORT HIGHLIGHTS

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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REPORT HIGHLIGHTS

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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REPORT HIGHLIGHTS

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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OVERVIEW

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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n OVERVIEW...
OVERVIEW

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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n Overview...
OVERVIEW

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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n Overview...
OVERVIEW

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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SAMPLE DATA

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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SAMPLE DATA

NGS Library Prep Market Scan: Pinpointing Customer Needs and
Opportunities for Growth
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SAMPLE DATA

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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METHODOLOGY

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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METHODOLOGY

NGS Library Prep Market Scan: Pinpointing Customer Needs and
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Report #13-006 - NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth

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Next generation sequencing (NGS) is a disruptive technology with an ever-increasing number of users and applications. As such, it is the fastest growing and most attractive segment of all the different technologies that comprise the genomics universe. On a global scale, we estimate that about 19% of life science researchers perform NGS in their work.

At the core of every cutting edge technology are the tools required to execute it, and next generation sequencing is no exception. Much of the hype surrounding NGS has centered on the instruments—ranging from benchtop models to those with production-scale capacity.

It is thanks to these tools that NGS has become a reality, allowing researchers to identify genomes, transcriptomes and epigenomes at high speeds and with a degree of clarity never before thought possible.

But preparing samples for sequencing is no small piece of the puzzle, as is evidenced by the growing number of companies that are jumping onto the NGS sample preparation bandwagon.

NGS Sample Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth targets the manufacturers and suppliers of NGS sample prep to help identify the usage, preferences and differentiators in a market that has attracted a significant number of players.

Suppliers recognize that there are fewer barriers to entry in the sample prep space compared to developing new sequencing platforms, thereby making sample prep product development more attractive—and on the rise.

Inherent in the sample prep market are multiple opportunities to address differences in sequencing platforms, methods of DNA fragmentation and, ultimately, the conversion of DNA or RNA samples into application-specific NGS libraries.

In this study, we will identify bottlenecks and areas that are causing the most frustration to researchers, but also point directly to opportunities for innovation.

We will cover areas of growth by application, segment and region. We will also examine how automation can conceivably change the speed, consistency, accuracy and ease with which researchers can expect to conduct next generation sequencing now and in the future.

With so many suppliers to choose from, how can a single supplier stand out? The foundation of a successful differentiation strategy is often a detailed understanding of the external environment.

In this report, we will

Identify the competitive mix by brand in the top product categories
-DNA libraries: whole genome, ChIP and methylated DNA
-Targeted resequencing: exome and panels
-RNA libraries: total RNA, mRNA and small RNA
Determine the key drivers of customer satisfaction in each product category
Gain insights into customer satisfaction and loyalty
With literally hundreds of products available from dozens of suppliers, the ability to fine-tune your unique message, value proposition and product portfolio is more important than ever.

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Report #13-006 - NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth

  1. 1. Report #13-006 Print $3,200 Site License $5,200 Print + Site License $5,200 Company-Wide License $6,500 BUY THE REPORT REPORT OVERVIEW NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth November 2013 ©2013 BioInformatics LLC www.gene2drug.com
  2. 2. Report #13-006 NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n Table of Contents n n Report Highlights........................................................................................................................................ 4 . n Overview...................................................................................................................................................................8 . n Sample Data.........................................................................................................................................................12 n Methodology....................................................................................................................................................15 n Pricing........................................................................................................................................................................17 . n ©2013 BioInformatics LLC Study Scope........................................................................................................................................................... 3 About Bioinformatics LLC................................................................................................................18 www.gene2drug.com 2 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  3. 3. STUDY SCOPE NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n STUDY SCope This report will help you to: n Identify the top NGS applications n Pinpoint the NGS applications with the greatest potential for growth in 2014 n Explore the range of biological samples used for NGS analysis n Estimate the number of researchers and labs currently performing NGS n Determine annual lab budgets associated with NGS sample and library preparation products n Approximate supplier share by laboratory spending n Assess market growth in terms of budget allocation in the next 12 months (through 2014) n Identify the leading suppliers of NGS library preparation products by NGS application n Gauge customer satisfaction, loyalty and likelihood to reorder NGS library preparation products n Recognize n Anticipate n Assess the bottlenecks associated with NGS library preparation the adoption of laboratory automation for NGS library workflow n Discover ©2013 BioInformatics LLC key drivers of customer satisfaction for NGS library preparation products the role of NGS service providers vis-à-vis sample preparation www.gene2drug.com 3 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  4. 4. REPORT HIGHLIGHTS NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n Report highlights Samples for NGS Library Preparation n Types of samples analyzed by NGS n Preparation n Sample of DNA- and RNA-based libraries for NGS types used to prepare DNA and RNA libraries n Number of NGS libraries prepared per week n Expected change in the number of NGS libraries prepared per week NGS Applications n Current NGS applications n Adoption of new NGS applications during the next 12 months n Percentage of NGS libraries prepared by application and throughput n Expected percentage of NGS library preparation by application and throughput during the next 12 months NGS Library Preparation n Types of NGS libraries prepared n DNA n NGS ©2013 BioInformatics LLC fragmentation methods library amplification www.gene2drug.com 4 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  5. 5. REPORT HIGHLIGHTS NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT ●n Report highlights (continued) n Where NGS libraries are prepared n Factors influencing where NGS libraries are prepared n Bottlenecks associated with NGS library prep workflow DNA Library Preparation n Types n Kit ● of double-stranded DNA used to make DNA libraries and reagent brands used to prepare DNA libraries n Satisfaction n Features with kit and reagent brands used to prepare DNA libraries that drive customer satisfaction with kit and reagent brands for preparing DNA libraries ● n Likelihood to reorder and recommend brands used for DNA library prep Targeted DNA Library Preparation n Types of double-stranded DNA used to make targeted DNA libraries n Target enrichment methods and products n Brand ● preference for post-enrichment NGS library preparation n Satisfaction ©2013 BioInformatics LLC with kit and reagent brands used to prepare targeted DNA libraries www.gene2drug.com 5 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  6. 6. REPORT HIGHLIGHTS NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT ●n Report highlights (continued) n Features that drive customer satisfaction with kit and reagent brands used to prepare targeted DNA libraries n Likelihood to reorder and recommend brands used for targeted DNA library prep RNA Library Preparation n Types of RNA used to make RNA-Seq libraries n Types of RNA analysis performed using NGS n Kit and reagent brands used to prepare RNA-Seq libraries n Brand preference for further RNA-Seq library manipulation n Satisfaction n Features with kit and reagent brands used to prepare RNA-Seq libraries that drive customer satisfaction with RNA-Seq kit and reagent brands n Likelihood to reorder and recommend brands used for RNA-Seq library prep Automation of NGS Sample and Library Preparation ●n Types of automation incorporated into NGS sample prep workflow n Automated n Motivation ● n Brands ● ©2013 BioInformatics LLC phases of NGS sample prep workflow to automate NGS library prep workflow of laboratory automation incorporated into NGS library prep workflow www.gene2drug.com 6 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  7. 7. REPORT HIGHLIGHTS NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT ●n Report highlights (continued) n Factors that influence brand selection for automation Lab Budgets for NGS Library Preparation ●n Budget n 2013 ● dedicated to NGS library preparation estimated supplier share NGS Demographics n Types of labs that utilize NGS n Primary n Brands application and models of NGS instrumentation n Location of NGS instrumentation n Providing n Learning NGS as a service about new methods and products for NGS library preparation n Laboratory n Areas n Time of research frame for adopting NGS n Utilization ©2013 BioInformatics LLC size of core labs by new users www.gene2drug.com 7 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  8. 8. OVERVIEW NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n OVERVIEW Next generation sequencing (NGS) is a disruptive technology with an everincreasing number of users and applications. As such, it is the fastest growing and most attractive segment of all the different technologies that comprise the genomics universe. On a global scale, we estimate that about 19% of life science researchers use NGS in their work. At the core of every cutting edge technology are the tools required to execute it, and next generation sequencing is no exception. Much of the hype surrounding NGS has centered on the instruments—ranging from benchtop models to those with production-scale capacity. It is thanks to these tools that NGS has become a reality, allowing researchers to identify genomes, transcriptomes and epigenomes at high speeds and with a degree of clarity never before thought possible. ©2013 BioInformatics LLC www.gene2drug.com 8 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  9. 9. OVERVIEW NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n Overview (continued) But preparing samples for sequencing is no small piece of the puzzle, as is evidenced by the growing number of companies that are jumping onto the NGS sample preparation bandwagon. NGS Sample Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth targets the manufacturers and suppliers of NGS sample prep to help identify the usage, preferences and differentiators in a market that has attracted a significant number of players. Suppliers recognize that there are fewer barriers to entry in the sample prep space compared to developing new sequencing platforms, thereby making sample prep product development more attractive—and on the rise. ©2013 BioInformatics LLC www.gene2drug.com 9 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  10. 10. OVERVIEW NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n Overview (continued) Inherent in the sample prep market are multiple opportunities to address differences in sequencing platforms, methods of DNA fragmentation and, ultimately, the conversion of DNA or RNA samples into application-specific NGS libraries. In this study, we will identify bottlenecks and areas that are causing the most frustration to researchers, but also point directly to opportunities for innovation. We will cover areas of growth by application, segment and region. We will also examine how automation can conceivably change the speed, consistency, accuracy and ease with which researchers can expect to conduct next generation sequencing now and in the future. With so many suppliers to choose from, how can a single supplier stand out? The foundation of a successful differentiation strategy is often a detailed understanding of the external environment. ©2013 BioInformatics LLC www.gene2drug.com 10 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  11. 11. OVERVIEW NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n Overview (continued) In this report, we will: ●n Identify the competitive mix by brand in the top product categories n DNA libraries: whole genome, ChIP and methylated DNA n Targeted resequencing: exome and panels n RNA libraries: total RNA, mRNA and small RNA n Determine the key drivers of customer satisfaction in each product category n Gain insights into customer satisfaction and loyalty With literally hundreds of products available from dozens of suppliers, the ability to fine-tune your unique message, value proposition and product portfolio is more important than ever. FREE data set through December 20, 2013 with purchase of the report. Regularly a $1,200 value. ©2013 BioInformatics LLC www.gene2drug.com 11 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  12. 12. SAMPLE DATA NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n sample data NGS Applications to be Adopted in the Next 12 Months Types of labs that perform NGS NGS service provider 3% 15% Methylated DNA (e.g., WGBS, RRBS) 13% Small RNA-Seq Whole transcriptome sequencing (e.g., RNA-Seq) Core lab/facility 23% 12% 12% mRNA-Seq 10% Whole genome resequencing Genome center 5% 10% Targeted sequencing RNA-protein interactions (e.g., CLIP-Seq) DNA-protein interactions (e.g., ChIP-Seq) Individual lab 69% 9% 9% 8% Whole exome resequencing 8% Metagenomics (e.g., Microbiome) De novo whole genome sequencing View Larger ©2013 BioInformatics LLC 7% View Larger www.gene2drug.com 12 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  13. 13. SAMPLE DATA NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n sample data Phases of NGS Sample Prep Workflow that Have Been Automated Types of RNA Analysis Performed Using NGS 61% 22% Sample purification 54% 20% Library preparation 38% 18% Library amplification 21% 16% Sample fragmentation 14% Post-PCR library manipulation Total transcriptome Expressed transcriptome Non-coding RNA Targeted amplicon/ expression profiling Library size selection I have not automated any phase of NGS sample prep workflow, but plan to do so I have not automated any phase of NGS sample prep workflow, and have no plans to do so View Larger ©2013 BioInformatics LLC 11% 22% 38% View Larger www.gene2drug.com 13 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  14. 14. SAMPLE DATA NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n sample data Role in lab Primary Focus of NGS Work Clinical diagnostics 9% Drug discovery/ pathway research 10% End-user only 14% Budget authority/ authorize purchases 48% Translational research 16% Basic discovery research 65% View Larger ©2013 BioInformatics LLC Evaluate/make recommendations 38% View Larger www.gene2drug.com 14 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  15. 15. METHODOLOGY NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n methodology NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth is based on responses to a 60-question online survey for life scientists conducted by BioInformatics LLC (Arlington, Virginia, USA). From October 9-23, 2013, 485 life scientists who currently use NGS in their research participated in the study. AREAS OF RESEARCH 55% Molecular Biology 48% Genetics/Genomics 29% Microbiology Cancer/Oncology 27% Cell Biology 26% 24% Biochemistry 23% Immunology/Virology 17% Protein Sciences/Proteomics 16% Drug Discovery 15% Neuroscience Stem Cell Biology/Regenerative Medicine ©2013 BioInformatics LLC 10% View Larger www.gene2drug.com 15 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  16. 16. METHODOLOGY NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth MARKET SEGMENTS JOB POSITIONS 52% Academic/University 12% Research Institute (non-profit) Lab Manager/Director/Supervisor/ Coordinator 7% Biopharmaceutical Company Hospital 4% Contract Research Organization 2% Physician 1% Chief 1% Administrator 1% Research Foundation 4% Laboratory Technician 1% Diagnostics 4% Department Head 2% Agriculture/Agricultural Biotechnology Company 13% Graduate Student/Research Assistant/PhD Student 2% Research Institute (for profit) 15% Professor/Assistant Professor/ Teacher 4% Pharmaceutical Company 17% Post Doctoral Fellow 5% University Medical Center 18% Staff Scientist 8% Government 24% Principal Investigator 1% REGION 1% View Larger View Larger ROW 18% North America 55% Europe 27% View Larger ©2013 BioInformatics LLC www.gene2drug.com 16 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  17. 17. PRICING NGS Library Prep Market Scan: Pinpointing Customer Needs and Opportunities for Growth BUY THE REPORT n ACT NOW Until December 20, 2013, the purchase of this report will include a FREE copy of the dataset, delivered in Excel format. Regularly a $1,200 value, a complimentary dataset will be included with your order: Print $3,200 Site License $5,200 Print + Site License $5,200 Company-Wide License $6,500 With your purchase of this report, we also invite you to set up a meeting with our report team of scientific and business analysts. We can answer any questions you may have about the survey results, and we can also share what we believe to be the significant trends affecting your market. Recent report titles: Digital Marketing to Life Scientists: Social Media and Email Best Practices Life Science Instrumentation: Brand Performance June 2013 The Market for Primary Cells & Stem Cell –Derived Cells May 2013 Enhancing the Customer Experience ©2013 BioInformatics LLC October 2013 March 2013 www.gene2drug.com 17 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005
  18. 18. BUY THE REPORT Click here for a complete list of our reports n ABOUT BIOINFORMATICS LLC Since our inception in 1994, BioInformatics LLC has provided critical market intelligence to leading companies serving the life science, medical and pharmaceutical industries. We support clients across the entire market spectrum—from scientific research to diagnostics and therapeutics—providing high-level management with market insights. Our published reports allow marketing professionals to share in the results of broad-based market studies that provide access to high-quality research at an affordable price. Our custom research is tailored to the specific needs of the companies’ executive management. For more information about BioInformatics’ product and service offerings, please visit our website at www.gene2drug.com, call 703.778.3080 x22, or email g.thompson@gene2drug.com ©2013 BioInformatics LLC www.gene2drug.com 18 @2013 BioInformatics, LLC n www.gene2drug.com n Report #13-005

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