The global phosphoramidite market is projected to reach $2,062.9 million by 2032 from $900.3 million in 2021, at a CAGR of 7.78% during the forecast period 2022-2032.

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Focus on Type, End User, and Region
Analysis and Forecast: 2022-2032
September 2022
Phosphoramidite
Market -
A Global and
Country Level
Analysis
Table of Content

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Table of Content
Executive Summary..........................................................................15
1. Market .......................................................................................19
1.1 Product Definition............................................................................................20
1.2 Inclusion and Exclusion..................................................................................20
2. Market Scope ............................................................................21
2.1 Key Questions Answered in the Report.........................................................22
3. Research Methodology ..............................................................23
3.1 Data Sources....................................................................................................24
3.1.1 Primary Data Source ...................................................................................24
3.1.2 Secondary Data Sources ............................................................................25
3.2 Market Estimation Model.................................................................................25
3.3 Criteria for Company Profiling........................................................................27
4. Market Overview........................................................................28
4.1 Introduction......................................................................................................28
4.2 Phosphoramidite Synthesis Process.............................................................29
4.2.1 Stability Considerations for Phosphoramidite .........................................30
4.3 Applications of Phosphoramidite Chemistry ................................................31
4.4 Future Trends in Phosphoramidite Industry .................................................32
4.5 COVID-19 Impact on Phosphoramidite Industry...........................................33
4.6 Current Market Size and Growth Potential, $Million, 2022-2032..................34
5. Industry Insights ........................................................................35
5.1 Overview...........................................................................................................35
5.2 Regulatory Considerations for Phosphoramidite.........................................35
5.2.1 Challenges ...................................................................................................35
5.2.2 Current Regulatory Landscape ..................................................................36

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5.2.3 GMP, Control Strategy, and Facility Considerations................................37
5.2.3.1 Brief Control Strategy ........................................................................................ 37
6. Market Dynamics .......................................................................39
6.1 Overview...........................................................................................................39
6.2 Impact Analysis ...............................................................................................39
6.3 Market Drivers..................................................................................................40
6.3.1 Increasing Synthetic Nucleotide Applications in Therapeutics ..............40
6.3.2 Growth in Synthetic Biology ......................................................................41
6.4 Market Restraints.............................................................................................41
6.4.1 Challenges in Developing Long Nucleotide Sequences ..........................41
6.4.2 Competition from Emerging DNA Synthesis Technologies ....................42
6.5 Market Opportunities.......................................................................................44
6.5.1 Utilize advanced tools for lowering manufacturing cost and
increasing production in gene synthesis..................................................44
7. Global Phosphoramidite Market, by Type, $Million, 2021-2032 ...45
7.1 Overview...........................................................................................................46
7.2 DNA Phosphoramidites...................................................................................46
7.3 RNA Phosphoramidites...................................................................................48
7.4 Labeled Phosphoramidites.............................................................................50
7.5 Other Phosphoramidites.................................................................................51
8. Global Phosphoramidite Market, by End Users, $Million, 2021-
2032 ..........................................................................................52
8.1 Overview...........................................................................................................53
8.2 Pharmaceutical and Biotechnology Companies...........................................53
8.3 Diagnostic Laboratories..................................................................................55
8.4 Synthetic Biology and Research Institutes ...................................................56

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9. Global Phosphoramidite Market, by Region, $Million, 2021-
2032 ..........................................................................................57
9.1 Overview...........................................................................................................58
9.2 North America..................................................................................................59
9.2.1 U.S. ...............................................................................................................60
9.2.2 Canada .........................................................................................................62
9.3 Europe ..............................................................................................................63
9.3.1 U.K. ...............................................................................................................64
9.3.2 Germany.......................................................................................................65
9.3.3 France...........................................................................................................66
9.3.4 Spain.............................................................................................................67
9.3.5 Italy ...............................................................................................................68
9.3.6 Rest-of-Europe.............................................................................................69
9.4 Asia-Pacific ......................................................................................................71
9.4.1 Japan............................................................................................................72
9.4.2 China ............................................................................................................73
9.4.3 India..............................................................................................................74
9.4.4 Rest-of-Asia-Pacific.....................................................................................75
9.5 Rest-of-the-World ............................................................................................76
10. Competitive Insights ..................................................................77
10.1 Key Strategies and Development...................................................................77
10.1.1 Overview ......................................................................................................77
10.1.2 Business Expansions .................................................................................77
10.1.3 Mergers and Acquisitions...........................................................................78
10.1.4 Funding Activities .......................................................................................79
10.1.5 Others...........................................................................................................79
10.2 Market Share Analysis (by Company) 2021...................................................80

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11. Market - Competitive Benchmarking & Company Profiles...........81
11.1 Overview...........................................................................................................82
11.2 Biosynth Carbosynth ......................................................................................83
11.2.1 Company Overview .....................................................................................83
11.2.2 Role of Biosynth Carbosynth in the Global Phosphoramidite
Market...........................................................................................................83
11.2.3 Key Competitors of the Company..............................................................83
11.2.4 Corporate strategies ...................................................................................84
11.2.4.1 Synergistic Activities.......................................................................................... 84
11.2.5 Analyst Perspective ....................................................................................84
11.3 Bioneer Corporation........................................................................................85
11.3.1 Company Overview .....................................................................................85
11.3.2 Role of Bioneer Corporation in the Global Phosphoramidite
Market...........................................................................................................85
11.3.3 Key Competitors of the Company..............................................................86
11.3.4 Analyst Perspective ....................................................................................86
11.4 Lumiprobe Corporation...................................................................................87
11.4.1 Company Overview .....................................................................................87
11.4.2 Role of Lumiprobe Corporation in the Global Phosphoramidite
Market...........................................................................................................87
11.4.3 Key Competitors of the Company..............................................................87
11.4.4 Analyst Perspective ....................................................................................88
11.5 QIAGEN N.V......................................................................................................89
11.5.1 Company Overview .....................................................................................89
11.5.2 Role of QIAGEN N.V. in the Global Phosphoramidite Market..................89
11.5.3 Key Competitors of the Company..............................................................89
11.5.4 Financials.....................................................................................................90
11.5.5 Analyst Perspective ....................................................................................92

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11.6 Danaher Corporation (IDT)..............................................................................93
11.6.1 Company Overview .....................................................................................93
11.6.2 Role of Danaher Corporation (IDT) in the Global Phosphoramidite
Market...........................................................................................................93
11.6.3 Key Competitors of the Company..............................................................94
11.6.4 Key Customers of the Company ................................................................94
11.6.5 Financials.....................................................................................................94
11.6.6 Analyst Perspective ....................................................................................96
11.7 TriLink BioTechnologies.................................................................................97
11.7.1 Company Overview .....................................................................................97
11.7.2 Role of TriLink BioTechnologies in the Global Phosphoramidite
Market...........................................................................................................97
11.7.3 Key Competitors of the Company..............................................................98
11.7.4 Financials.....................................................................................................98
11.7.5 Business Strategies ..................................................................................100
11.7.6 Analyst Perspective ..................................................................................100
11.8 Creative Biolabs.............................................................................................102
11.8.1 Company Overview ...................................................................................102
11.8.2 Role of Creative Biolabs in the Global Phosphoramidite Market..........102
11.8.3 Key Competitors of the Company............................................................102
11.9 PolyOrg, Inc....................................................................................................103
11.9.1 Company Overview ...................................................................................103
11.9.2 Role of PolyOrg, Inc. in the Global Phosphoramidite Market................103
11.9.3 Key Competitors of the Company............................................................103
11.10 Hongene Biotech Corporation......................................................................104
11.10.1 Company Overview.............................................................................104
11.10.2 Role of Hongene Biotech Corporation in the Global
Phosphoramidite Market...........................................................................104

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11.10.3 Key Competitors of the Company .....................................................105
11.10.4 Business Strategies............................................................................105
11.11 ChemGenes....................................................................................................106
11.11.1 Company Overview.............................................................................106
11.11.2 Role of ChemGenes in the Global Phosphoramidite Market...........106
11.11.3 Key Competitors of the Company .....................................................106
11.12 BOC Sciences ................................................................................................107
11.12.1 Company Overview.............................................................................107
11.12.2 Role of BOC Sciences in the Global Phosphoramidite Market .......107
11.12.3 Key Competitors of the Company .....................................................108
11.12.4 Key Customers of the Company........................................................108
11.13 Tokyo Chemical Industry Co., Ltd. (TCI)......................................................109
11.13.1 Company Overview.............................................................................109
11.13.2 Role of Tokyo Chemical Industry Co., Ltd. in the Global
Phosphoramidite Market...........................................................................109
11.13.3 Key Competitors of the Company .....................................................110
11.14 LGC Science Group Holdings Limited.........................................................111
11.14.1 Company Overview.............................................................................111
11.14.2 Role of LGC Science Group Holdings Limited in the Global
Phosphoramidite Market...........................................................................111
11.14.3 Key Competitors of the Company .....................................................112
11.14.4 Key Customers of the Company........................................................112
11.14.5 Financials ............................................................................................113
11.14.6 Business Strategies............................................................................114
11.14.7 Analyst Perspective............................................................................114
11.15 AAT Bioquest, Inc..........................................................................................115
11.15.1 Company Overview.............................................................................115

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11.15.2 Role of AAT Bioquest, Inc. in the Global Phosphoramidite
Market.........................................................................................................115
11.15.3 Key Competitors of the Company .....................................................115
11.16 Thermo Fisher Scientific, Inc........................................................................116
11.16.1 Company Overview.............................................................................116
11.16.2 Role of Thermo Fisher Scientific, Inc. in the Global
Phosphoramidite Market...........................................................................116
11.16.3 Key Competitors of the Company .....................................................116
11.16.4 Financials ............................................................................................117
11.16.5 Analyst Perspective............................................................................119
11.17 Merck KGaA ...................................................................................................120
11.17.1 Company Overview.............................................................................120
11.17.2 Role of Merck KGaA in the Global Phosphoramidite Market ..........120
11.17.3 Key Competitors of the Company .....................................................120
11.17.4 Financials ............................................................................................121
11.17.5 Analyst Perspective............................................................................123

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List of Figures
Figure 1: Global Phosphoramidite Market Dynamics
Figure 2: Global Phosphoramidite Market (by Type), $Million, 2021 and 2032
Figure 3: Global Phosphoramidite Market (by End User), $Million, 2021 and 2032
Figure 4: Global Phosphoramidite Market (by Region), $Million, 2021-2032
Figure 5: Global Phosphoramidite Market Segmentation
Figure 6: Global Phosphoramidite Market Research Methodology
Figure 7: Primary Research Methodology
Figure 8: Volume-Based Market Sizing and Forecasting Methodology
Figure 9: Structure of a Standard 2’-Deoxyadenosine Phosphoramidite
Figure 10: Workflow of Phosphoramdite Synthesis Chemistry to Produce Oligonucleotides
Figure 11: Phosphoramidite Synthesis Cycle
Figure 12: Factors Impacting the Stability of Phosphoramidites
Figure 13: Phosphoramidite Key Application Areas
Figure 14: Global Phosphoramidite Market, $Million, 2021-2032
Figure 15: Challenges for Phosphoramidite as a Drug Product
Figure 16: Control Strategy: Phosphoramidite Elements
Figure 17: Elements of Microbial Control Strategy
Figure 18: Details of GMP, Control Strategy, and Facility Considerations
Figure 19: Market Dynamics
Figure 20: Impact Analysis
Figure 21: Factors Influencing Rise in Oligonucleotide Demand and Growing Market
Figure 22: Breakthrough Achievements in Synthetic Biology, 2016-2020
Figure 23: Key Competitors Impacting Global Phosphoramidite Market Growth in Future
Figure 24: Share of Global Phosphoramidite Market (by Type), $Million, 2021 and 2032
Figure 25: Characteristics of DNA Phosphoramidites
Figure 26: Global Phosphoramidite Market (DNA Phosphoramidites), $Million, 2021-2032
Figure 27: Global Phosphoramidite Market (RNA Phosphoramidites), $Million, 2021-2032
Figure 28: Global Phosphoramidite Market (Labeled Phosphoramidites), $Million, 2021-2032
Figure 29: Global Phosphoramidite Market (Other Phosphoramidites), $Million, 2021-2032
Figure 30: Share of Global Phosphoramidite Market (by End User), $Million, 2021 and 2032
Figure 31: Global Phosphoramidite Market (Pharmaceutical and Biotechnology Companies), $Million, 2021-
2032
Figure 32: Global Phosphoramidite Market (Diagnostic Laboratories), $Million, 2021-2032

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Figure 33: Global Phosphoramidite Market (Synthetic Biology and Research Institutes), $Million, 2021-2032
Figure 34: Global Phosphoramidite Market (by Region), $Million, 2021-2032
Figure 35: Market Dynamics of North America Phosphoramidite Market
Figure 36: North America Phosphoramidite Market, $Million, 2021-2032
Figure 37: Projections of the Older Adult Population in the U.S.: 2016 to 2060 (Million)
Figure 38: U.S. Phosphoramidite Market, $Million, 2021-2032
Figure 39: Canada Phosphoramidite Market, $Million, 2021-2032
Figure 40: Market Dynamics of Europe Phosphoramidite Market
Figure 41: Europe Phosphoramidite Market, $Million, 2021-2032
Figure 42: U.K. Phosphoramidite Market, $Million, 2021-2032
Figure 43: Germany Phosphoramidite Market, $Million, 2021-2032
Figure 44: France Phosphoramidite Market, $Million, 2021-2032
Figure 45: Spain Phosphoramidite Market, $Million, 2021-2032
Figure 46: Italy Phosphoramidite Market, $Million, 2021-2032
Figure 47: Rest-of-Europe Phosphoramidite Market, $Million, 2021-2032
Figure 48: Market Dynamics of the Asia-Pacific Phosphoramidite Market
Figure 49: Asia-Pacific Phosphoramidite Market, $Million, 2021-2032
Figure 50: Japan Phosphoramidite Market, $Million, 2021-2032
Figure 51: China Phosphoramidite Market, $Million, 2021-2032
Figure 52: India Phosphoramidite Market, $Million, 2021-2032
Figure 53: Rest-of-APAC Phosphoramidite Market, $Million, 2021-2032
Figure 54: Rest-of-the-World Phosphoramidite Market, $Million, 2021-2032
Figure 55: Figure: Share of Key Developments, January 2019-August 2022
Figure 56: Business Expansions (by Company), January 2019-August 2022
Figure 57: Merger and Acquisition Activities (by Company), January 2019-August 2022
Figure 58: Market Share Analysis for the Global Phosphoramidite Market, 2021
Figure 59: Total Number of Companies Profiled
Figure 60: Bioneer Corporation’s Phosphoramidite Manufacturing Capacity
Figure 61: Bioneer Corporation: Selective Product Portfolio
Figure 62: Lumiprobe Corporation: Selective Product Portfolio
Figure 63: QIAGEN N.V.: Selective Product Profile
Figure 64: QIAGEN N.V.: Overall Financials, 2019-2021
Figure 65: QIAGEN N.V.: Revenue (by Segment), $Million, 2019-2021
Figure 66: QIAGEN N.V.: Revenue (by Region), $Million, 2019-2021

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Figure 67: QIAGEN N.V.: R&D Expenditure, 2019-2021
Figure 68: Danaher Corporation (IDT): Selective Product Portfolio
Figure 69: Danaher Corporation (IDT): Overall Financials, $Million, 2019-2021
Figure 70: Danaher Corporation (IDT): Revenue (by Segment), $Million, 2019-2021
Figure 71: Danaher Corporation (IDT): Revenue (by Region), $Million, 2019-2021
Figure 72: Danaher Corporation (IDT), R&D Expenditure, $Million, 2019-2021
Figure 73: TriLink BioTechnologies: Selective Product Portfolio
Figure 74: Maravai LifeSciences Holdings, Inc.: Overall Financials, $Million, 2019-2021
Figure 75: Maravai LifeSciences Holdings, Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 76: Maravai LifeSciences Holdings, Inc.: Revenue (by Region), $Million, 2019-2021
Figure 77: Maravai LifeSciences Holdings, Inc.: R&D Expenditure, $Million, 2019-2021
Figure 78: Creative Biolabs: Selective Product Portfolio
Figure 79: PolyOrg, Inc.: Selective Product Portfolio
Figure 80: Hongene Biotech Corporation: Selective Product Portfolio
Figure 81: ChemGenes: Selective Product Portfolio
Figure 82: BOC Sciences: Selective Product Portfolio
Figure 83: Tokyo Chemical Industry Co., Ltd.: Selective Product Portfolio
Figure 84: LGC Science Group Holdings Limited: Selective Product Portfolio
Figure 85: LGC Science Group Holdings Limited: Overall Financials, $Million, 2019-2021
Figure 86: LGC Science Group Holdings Limited: Revenue (by Region), $Million, 2019-2021
Figure 87: AAT Bioquest, Inc.: Selective Product Portfolio
Figure 88: Thermo Fisher Scientific, Inc.: Selective Product Portfolio
Figure 89: Thermo Fisher Scientific, Inc.: Overall Financials, 2019-2021
Figure 90: Thermo Fisher Scientific, Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 91: Thermo Fisher Scientific, Inc.: Revenue (by Region), $Million, 2019-2021
Figure 92: Thermo Fisher Scientific, Inc.: R&D Expenditure, $Million, 2019-2021
Figure 93: Merck KGaA: Selective Product Portfolio
Figure 94: Merck KGaA: Overall Financials, $Million, 2019-2021
Figure 95: Merck KGaA: Revenue (by Segment), $Million, 2019-2021
Figure 96: Merck KGaA: Revenue (by Region), $Million, 2019-2021
Figure 97: Merck KGaA: R&D Expenditure, $Million, 2019-2021

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List of Tables
Table 1: Companies and COVID-19 Impact
Table 2: Guideline Summary for Phosphoramidites
Table 3: Decreased Coupling Efficiency with Extending Oligonucleotide Sequence
Table 4: Key Characteristics of Enzymatic-based and Phosphoramidite Synthesis
Table 5: Examples of RNA Phosphoramidites
Table 6: List of Approved Oligonucleotide-Based Therapies, 1998-2020

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