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DIETARY FAT
Fat requirements
• In developed countries dietary fats
provide 30 to 40 per cent of total energy
intake. The WHO Expert committee on
Prevention of Coronary Heart Disease
has recommended only 20 to 30 per cent
of total dietary energy to be provided by
fats. At least 50 per cent of fat intake
should consist of vegetable oils rich in
essential fatty acids.
Fatty acid content of different
fats
• Saturated Monounsaturated Polyunsaturated
• Fats fatty acids fatty acids fatty acids
• Coconut oil 92 6 2
• Palm oil 46 44 10
• Cotton seed oil 25 25 50
• Groundnut oil 19 50 31
• Safflower oil 10 15 75
• Sunflower oil 8 27 65
• Corn oil 8 27 65
• Soya bean oil 14 24 62
• Butter 60 37 3
• vegetable fats are rich sources of essential
fatty acids which are needed by the body for
growth, structural integrity of the cell
membrane and decreased platelet
adhesiveness.
• Diets rich in EFA have been reported to
reduce serum cholesterol and low-density
lipoproteins.
• Polyunsaturated fatty acids are precursors
of prostaglandins.
Essential Fatty Acids
The Essential Fats are a group of fatty acids
that are essential to human health.
• Omega-3 (3) – Linolenic acid
• Omega-6 (6) – Linoleic acid
Structure of EFAs
LINOLEIC ACIDS (Omega 6)
Eighteen-carbon essential fatty acids that
contain two double bonds.
• 18:2 (9,12)
– LINOLENIC ACIDS (Omega 3)
Eighteen-carbon essential fatty acids that
contain three double bonds
18:3 (9,12,15)
Function of EFAs
• Formation of healthy cell membranes
• Proper development and functioning of the brain
and nervous system
• Production of hormone-like substances called
Eicosanoids
–Thromboxanes
–Leukotrienes
–Prostaglandins
Responsible for regulating blood pressure, blood
viscosity, vasoconstriction, immune and inflammatory
responses.
Omega-3s
• Sources:
Walnuts
Wheat germ oil
Flaxeed oil/canola oil
Fish liver oils/Fish eggs
Human Milk
Organ meats
Seafood/Fatty fish
- albacore tuna
- mackerel
- salmon
-sardines
Benefits of Omega-3s
• Lower PG2s
• Anti-inflammatory
• Lower triglyceride and
cholesterol levels
• Cancer prevention
• Renal maintenance
• Increase insulin sensitivity
• Enhance thermogenesis and
lipid metabolism
• Benefits vision and brain
function
• Decrease Skin inflammation
• Inhibit platelet adhesion
Platelet aggregation, cardiovascular
diseases, and inflammation
Sources:
Corn oil
Peanut oil
Cottonseed oil
Soybean oil
Many plant oils
Omega-6s
Benefits of Omega-6s
Specifically, omega-6 fatty
acids with a high GLA
content may help to:
• Reduce inflammation of
rheumatoid arthritis
• Relieve the discomforts of
PMS, endometriosis, and
fibrocystic breasts.
• Reduce the symptoms of
eczema and psoriasis.
• Clear up acne and rosacea.
• Prevent and improve
diabetic neuropathy.
• Excessive amounts of
omega-6 (PUFA) and a very
high omega-6/omega-3 ratio
has been shown to promote
the pathogenesis of many
diseases:
-cardiovascular disease
-cancer
-Inflammatory and
autoimmune diseases
Essential Fatty Acid
Deficiency Side Effects
• hemorrhagic dermatitis
• skin atrophy
• scaly dermatitis
• dry skin
• weakness
• impaired vision
• tingling sensations
• mood swings
• edema
• high blood pressure
• high triglycerides
• hemorrhagic folliculitis
• hemotologic disturbances
(ex: sticky platelets)
• immune and mental
deficiencies
• impaired growth
Dermatitis, Atopic in an Infant
and on a Young Girl's Face
Differing characteristics -3 and -6
Essential Fatty Acid Deficiencies
Omega-3 (-Linolenic Acid) Omega-6 (Linoleic Acid)
Clinical
Features
Normal skin, growth, reproduction
Reduced learning
Abnormal electroretinogram
Impaired vision
Polydipsia
Growth retardation
Skin lesions
Reproductive failure
Fatty liver
Polydipsia
Biochemical
markers
Decreased 18:3 -3 and 22:6  -3
Increased 22:4 -6 and 22:5  7
Increased 20:3 -9(only if  -6 also low)
Decreased 18:2 -6 and 20:4 -6
Increased 20:3 -9 (only if  -3 also
low)
Who are at risk for deficiency?
• Long-term TPN patients
without adequate lipid
• Cystic Fibrosis
• Low Birth Weight Infants
• Premature infants
• Severely malnourished
patients
• Patients on Long-term
MCT as fat source
• Patients with fat
malabsorption
• Acrodermatitis
Enteropathica
• Hepatorenal Syndrome
• Multisystem neuronal
degradation
• Crohn’s disease
• Cirrhosis and
alcoholism
• Reye’s Syndrome
• Short bowel syndrome
Recommendations: Adults
• Requirements for EFAs
are 1 to 2% of dietary
calories for adults.
AI for Adults
Men
19- >70 yrs 1.6 g/day of a-linolenic acid
1.7 g/day of linoleic acid
Women
19- >70 yrs 1.1 g/day of a-linolenic acid
1.2 g/day of linoleic acid
 Recommended 0.2% to
1% of total calories
should be provided by
omega-3 fatty acids.
Recommendations: Infants &
Children
• The American Academy
of Pediatrics recommends
that infant milk formula
should provide at least
2.7% of total kilocalories
in the form of linoleic
acid.
• Of note, human milk
provides 3.5% to as high
as 12% of total kilocalories
in the form of linoleic acid
depending on the fat
composition of the
maternal diet.
AI for Infants and Children
0-6 mos 0.5 g/day of n-3 PUFA
7-12 mos 0.5 g/day of n-3 PUFA
1-3 yrs 0.7 g/day of -linolenic acid
4-8 yrs 0.9 g/day of  -linolenic acid
Boys
9-13 yrs 1.2 g/day of  -linolenic acid
14-18 yrs 1.6 g/day o -linolenic acid
Girls
9-13 yrs 1.0 g/day of  -linolenic acid
14-18 yrs 1.1 g/day of  -linolenic acid
)
Obesity
• How do we define obesity?
–By culture
–By science
OBESITY
• Prevalence in US: 33% of adults and 25%
of children are obese
• Risks associated with obesity: diabetes,
hypertension, stroke, heart disease, elevated
total cholesterol, low HDL-cholesterol,
certain types of cancer, gallbladder disease
What Causes Obesity
• 3 major factors contribute to the development of
obesity
– 1) Genetic background
• Heredity may account for approx. 25-40% of obesity
but this is very poorly understood
• Effects on metabolism (rare); traits that predispose
(common)
– 2) Dietary intake
– 3) Physical activity
Measuring Body Fatness
• Body Mass Index (BMI)- widely used
– Calculated by dividing body weight (in kg)
by height (in meters) squared
• 19-25 is considered acceptable
• overweight is btw. 25-30
• > 30 obesity
We Do Need Body Fat
• For survival we need:
– 3-5% for men
– 10-12% for women
• Low body fat associated with
– Delayed physical maturation during adolescence
– Infertility
– Accelerated bone loss
Body fat location is important
• Apple = Abdomen
• Pear =
Hips & thighs
• Apple -> risk of heart
disease
• waist/hip ratio:
>0.8 F, > 0.95 M
indicates apple shape
Limitations of BMI
Both men have a BMI of 31
CLASS OVER…
dietary fat.ppt

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dietary fat.ppt

  • 2. Fat requirements • In developed countries dietary fats provide 30 to 40 per cent of total energy intake. The WHO Expert committee on Prevention of Coronary Heart Disease has recommended only 20 to 30 per cent of total dietary energy to be provided by fats. At least 50 per cent of fat intake should consist of vegetable oils rich in essential fatty acids.
  • 3.
  • 4. Fatty acid content of different fats • Saturated Monounsaturated Polyunsaturated • Fats fatty acids fatty acids fatty acids • Coconut oil 92 6 2 • Palm oil 46 44 10 • Cotton seed oil 25 25 50 • Groundnut oil 19 50 31 • Safflower oil 10 15 75 • Sunflower oil 8 27 65 • Corn oil 8 27 65 • Soya bean oil 14 24 62 • Butter 60 37 3
  • 5.
  • 6. • vegetable fats are rich sources of essential fatty acids which are needed by the body for growth, structural integrity of the cell membrane and decreased platelet adhesiveness. • Diets rich in EFA have been reported to reduce serum cholesterol and low-density lipoproteins. • Polyunsaturated fatty acids are precursors of prostaglandins.
  • 7. Essential Fatty Acids The Essential Fats are a group of fatty acids that are essential to human health. • Omega-3 (3) – Linolenic acid • Omega-6 (6) – Linoleic acid
  • 8. Structure of EFAs LINOLEIC ACIDS (Omega 6) Eighteen-carbon essential fatty acids that contain two double bonds. • 18:2 (9,12) – LINOLENIC ACIDS (Omega 3) Eighteen-carbon essential fatty acids that contain three double bonds 18:3 (9,12,15)
  • 9. Function of EFAs • Formation of healthy cell membranes • Proper development and functioning of the brain and nervous system • Production of hormone-like substances called Eicosanoids –Thromboxanes –Leukotrienes –Prostaglandins Responsible for regulating blood pressure, blood viscosity, vasoconstriction, immune and inflammatory responses.
  • 10. Omega-3s • Sources: Walnuts Wheat germ oil Flaxeed oil/canola oil Fish liver oils/Fish eggs Human Milk Organ meats Seafood/Fatty fish - albacore tuna - mackerel - salmon -sardines
  • 11. Benefits of Omega-3s • Lower PG2s • Anti-inflammatory • Lower triglyceride and cholesterol levels • Cancer prevention • Renal maintenance • Increase insulin sensitivity • Enhance thermogenesis and lipid metabolism • Benefits vision and brain function • Decrease Skin inflammation • Inhibit platelet adhesion
  • 12. Platelet aggregation, cardiovascular diseases, and inflammation Sources: Corn oil Peanut oil Cottonseed oil Soybean oil Many plant oils Omega-6s
  • 13. Benefits of Omega-6s Specifically, omega-6 fatty acids with a high GLA content may help to: • Reduce inflammation of rheumatoid arthritis • Relieve the discomforts of PMS, endometriosis, and fibrocystic breasts. • Reduce the symptoms of eczema and psoriasis. • Clear up acne and rosacea. • Prevent and improve diabetic neuropathy. • Excessive amounts of omega-6 (PUFA) and a very high omega-6/omega-3 ratio has been shown to promote the pathogenesis of many diseases: -cardiovascular disease -cancer -Inflammatory and autoimmune diseases
  • 14. Essential Fatty Acid Deficiency Side Effects • hemorrhagic dermatitis • skin atrophy • scaly dermatitis • dry skin • weakness • impaired vision • tingling sensations • mood swings • edema • high blood pressure • high triglycerides • hemorrhagic folliculitis • hemotologic disturbances (ex: sticky platelets) • immune and mental deficiencies • impaired growth
  • 15. Dermatitis, Atopic in an Infant and on a Young Girl's Face
  • 16. Differing characteristics -3 and -6 Essential Fatty Acid Deficiencies Omega-3 (-Linolenic Acid) Omega-6 (Linoleic Acid) Clinical Features Normal skin, growth, reproduction Reduced learning Abnormal electroretinogram Impaired vision Polydipsia Growth retardation Skin lesions Reproductive failure Fatty liver Polydipsia Biochemical markers Decreased 18:3 -3 and 22:6  -3 Increased 22:4 -6 and 22:5  7 Increased 20:3 -9(only if  -6 also low) Decreased 18:2 -6 and 20:4 -6 Increased 20:3 -9 (only if  -3 also low)
  • 17. Who are at risk for deficiency? • Long-term TPN patients without adequate lipid • Cystic Fibrosis • Low Birth Weight Infants • Premature infants • Severely malnourished patients • Patients on Long-term MCT as fat source • Patients with fat malabsorption • Acrodermatitis Enteropathica • Hepatorenal Syndrome • Multisystem neuronal degradation • Crohn’s disease • Cirrhosis and alcoholism • Reye’s Syndrome • Short bowel syndrome
  • 18. Recommendations: Adults • Requirements for EFAs are 1 to 2% of dietary calories for adults. AI for Adults Men 19- >70 yrs 1.6 g/day of a-linolenic acid 1.7 g/day of linoleic acid Women 19- >70 yrs 1.1 g/day of a-linolenic acid 1.2 g/day of linoleic acid  Recommended 0.2% to 1% of total calories should be provided by omega-3 fatty acids.
  • 19. Recommendations: Infants & Children • The American Academy of Pediatrics recommends that infant milk formula should provide at least 2.7% of total kilocalories in the form of linoleic acid. • Of note, human milk provides 3.5% to as high as 12% of total kilocalories in the form of linoleic acid depending on the fat composition of the maternal diet. AI for Infants and Children 0-6 mos 0.5 g/day of n-3 PUFA 7-12 mos 0.5 g/day of n-3 PUFA 1-3 yrs 0.7 g/day of -linolenic acid 4-8 yrs 0.9 g/day of  -linolenic acid Boys 9-13 yrs 1.2 g/day of  -linolenic acid 14-18 yrs 1.6 g/day o -linolenic acid Girls 9-13 yrs 1.0 g/day of  -linolenic acid 14-18 yrs 1.1 g/day of  -linolenic acid )
  • 20. Obesity • How do we define obesity? –By culture –By science
  • 21. OBESITY • Prevalence in US: 33% of adults and 25% of children are obese • Risks associated with obesity: diabetes, hypertension, stroke, heart disease, elevated total cholesterol, low HDL-cholesterol, certain types of cancer, gallbladder disease
  • 22. What Causes Obesity • 3 major factors contribute to the development of obesity – 1) Genetic background • Heredity may account for approx. 25-40% of obesity but this is very poorly understood • Effects on metabolism (rare); traits that predispose (common) – 2) Dietary intake – 3) Physical activity
  • 23. Measuring Body Fatness • Body Mass Index (BMI)- widely used – Calculated by dividing body weight (in kg) by height (in meters) squared • 19-25 is considered acceptable • overweight is btw. 25-30 • > 30 obesity
  • 24. We Do Need Body Fat • For survival we need: – 3-5% for men – 10-12% for women • Low body fat associated with – Delayed physical maturation during adolescence – Infertility – Accelerated bone loss
  • 25. Body fat location is important • Apple = Abdomen • Pear = Hips & thighs • Apple -> risk of heart disease • waist/hip ratio: >0.8 F, > 0.95 M indicates apple shape
  • 26. Limitations of BMI Both men have a BMI of 31
  • 27.