Part 1 discusses big CSS problems like high specificity, redundancy, and inconsistency. Part 2 explains how to build a style guide by creating a pattern library that catalogs UI components and is written in CSS. It includes atoms, molecules, and infrastructure elements. Part 3 discusses maintaining the style guide through monitoring tools, linting, and periodic analysis with CSS Stats and Lighthouse to check for consistency, accessibility, and performance issues. The presentation provides resources for building and sustaining an effective style guide.