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ENDOMETRIOSIS
Presentation by Allison Aboud
Table of Contents
 Definition and Wood Root
 Physiopathology
 Epidemiology
 Etiology and Theories
 S/S
 Dx
 Differential Dx
 Tx
 Px
 PPx
 Conclusion
 Bibliography
 Video
END/O-
Meaning
Within
Meaning
Mother or
Uterus
Meaning
Abnormal
Condition
METRA -OSIS
ENDOMETRIOSI
S
The abnormal condition where endometrium, or tissue that
lines the uterus, also grows outside of the uterus.
Physiopathology
Epidemiology
 Endometriosis affects 2 -10% of American women aged
25 - 40. *
 30 – 50% of women found with the disease experience
infertility. **
 Can be found in post-menopausal women as well. *
Increased Risk Factors:
 Women with a 'First Degree' relative with the disease. *
 Women with a naturally abnormal uterus. *
 Women who give birth for the first time over the age of
30. *
 Black and Hispanic individuals are found to be half as
likely as Caucasians to develop Endometriosis. Asian
individuals are found to be slightly higher in cases than
all other ethnicities, according to clinical studies. ***
* John Hopkins Medicine
** American Society for Reproductive Medicine
*** Kronemyer, 2019
SPECIFIC
ETIOLOGY?
Idiopathic Disease
Four Theories of Endometriosis
Theory One: Called Retrograde Menstruation, tissue from the Uterus backs up
through the Fallopian Tubes into the Abdominal Cavity where the cells attach and
grow.
According to Research by John Hopkins Medicine
Theory Two: Cells in any location may have the ability to transform themselves into
Endometrial cells, when triggered by Estrogen or Progesterone.
Theory Three: Endometrial tissue may travel to other parts of the body by Blood or
through Lymphatic Channels, much like cancer cells.
Theory Four: There may be a genetic answer. There is proven to be higher risks of
Endometriosis in diagnosed, blood related females.
Signs
■ Dismenorrhea
■ Dyspareunia
■ Dysuria
■ Dyschezia
■ Nausea
■ Menorrhagia
■ Oligomenorrhea
■ Diarrhea
■ Infertility
■ Peritoneal Adhesion
■ Hemorrhagic Ovarian Cysts
& Symptoms
Diagnosis
• Palpation
• Ultrasound
• Pelvic MRI
• Laparoscopy
DIFFERENTIAL DX
PCOS- Poly-Cystic Ovary Syndrome
 Hormonal Imbalances
 Hirsutism
 Thinning Hair
 Insulin Resistance
*Slide Credit: Office onWomen's Health, USDHHS
Treatment
 Laparotomy
 Hormonal Birth Control
 Hysterectomy
Prognosis
Endometriosis is not a life threatening
disease.
The pain, discomfort, medication use and possible
surgical removals can be a lifelong commitment.
Linked to Adenomyosis and Ovarian Cancer, but in
small probabilities.
PROPHYLAXIS
Although you cannot prevent Endometriosis, there are some ways you might
be able to lower Estrogen levels and reduce your risk.
• Exercising regularly. (Recommended more than four hours a week.)
• If you take birth control, choosing an option with lower doses of the hormone
Estrogen
• Reducing alcohol and caffeine intake to one beverage a day.
*Info by Office on Womens Health, US Dept. Health and Human Services
CONCLUSION
 Listen to your body.
 Menstruation should not be debilitating.
BIBLIOGRAPHY
 "Endometriosis: Does it Cause Infertility?" ReproductiveFacts.org, American Society for Reproductive
Medicine, 2016, https://www.reproductivefacts.org/news-and-publications/patient-fact-sheets-and-
booklets/documents/fact-sheets-and-info-booklets/endometriosis-does-it-cause-
infertility/?_ga=2.99432606.1232864400.1612656037-1162994308.1612656037
 "Endometriosis." Health, John Hopkins Medicine, https://www.hopkinsmedicine.org/health/conditions-and-
diseases/endometriosis
 Kronemyer, Bob. "How Race/Ethnicity Influences Endometriosis." Contemporary OB/GYN, 22 May
2019, https://www.contemporaryobgyn.net/view/how-raceethnicity-influences-endometriosis
 "Endometriosis." US Department of Health and Human Services, Office on Womens
Health. https://www.womenshealth.gov/a-z-topics/endometriosis
 "Polycystic Ovary Syndrome." US Department of Health and Human Services, Office on
Womens Health. https://www.womenshealth.gov/a-z-topics/polycystic-ovary-syndrome
Source: AbbVie on Youtube
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Endometriosis

  • 2. Table of Contents  Definition and Wood Root  Physiopathology  Epidemiology  Etiology and Theories  S/S  Dx  Differential Dx  Tx  Px  PPx  Conclusion  Bibliography  Video
  • 3. END/O- Meaning Within Meaning Mother or Uterus Meaning Abnormal Condition METRA -OSIS ENDOMETRIOSI S The abnormal condition where endometrium, or tissue that lines the uterus, also grows outside of the uterus.
  • 5. Epidemiology  Endometriosis affects 2 -10% of American women aged 25 - 40. *  30 – 50% of women found with the disease experience infertility. **  Can be found in post-menopausal women as well. * Increased Risk Factors:  Women with a 'First Degree' relative with the disease. *  Women with a naturally abnormal uterus. *  Women who give birth for the first time over the age of 30. *  Black and Hispanic individuals are found to be half as likely as Caucasians to develop Endometriosis. Asian individuals are found to be slightly higher in cases than all other ethnicities, according to clinical studies. *** * John Hopkins Medicine ** American Society for Reproductive Medicine *** Kronemyer, 2019
  • 7. Four Theories of Endometriosis Theory One: Called Retrograde Menstruation, tissue from the Uterus backs up through the Fallopian Tubes into the Abdominal Cavity where the cells attach and grow. According to Research by John Hopkins Medicine Theory Two: Cells in any location may have the ability to transform themselves into Endometrial cells, when triggered by Estrogen or Progesterone.
  • 8. Theory Three: Endometrial tissue may travel to other parts of the body by Blood or through Lymphatic Channels, much like cancer cells. Theory Four: There may be a genetic answer. There is proven to be higher risks of Endometriosis in diagnosed, blood related females.
  • 9. Signs ■ Dismenorrhea ■ Dyspareunia ■ Dysuria ■ Dyschezia ■ Nausea ■ Menorrhagia ■ Oligomenorrhea ■ Diarrhea ■ Infertility ■ Peritoneal Adhesion ■ Hemorrhagic Ovarian Cysts & Symptoms
  • 10. Diagnosis • Palpation • Ultrasound • Pelvic MRI • Laparoscopy
  • 11. DIFFERENTIAL DX PCOS- Poly-Cystic Ovary Syndrome  Hormonal Imbalances  Hirsutism  Thinning Hair  Insulin Resistance *Slide Credit: Office onWomen's Health, USDHHS
  • 12. Treatment  Laparotomy  Hormonal Birth Control  Hysterectomy
  • 13. Prognosis Endometriosis is not a life threatening disease. The pain, discomfort, medication use and possible surgical removals can be a lifelong commitment. Linked to Adenomyosis and Ovarian Cancer, but in small probabilities.
  • 14. PROPHYLAXIS Although you cannot prevent Endometriosis, there are some ways you might be able to lower Estrogen levels and reduce your risk. • Exercising regularly. (Recommended more than four hours a week.) • If you take birth control, choosing an option with lower doses of the hormone Estrogen • Reducing alcohol and caffeine intake to one beverage a day. *Info by Office on Womens Health, US Dept. Health and Human Services
  • 15. CONCLUSION  Listen to your body.  Menstruation should not be debilitating.
  • 16. BIBLIOGRAPHY  "Endometriosis: Does it Cause Infertility?" ReproductiveFacts.org, American Society for Reproductive Medicine, 2016, https://www.reproductivefacts.org/news-and-publications/patient-fact-sheets-and- booklets/documents/fact-sheets-and-info-booklets/endometriosis-does-it-cause- infertility/?_ga=2.99432606.1232864400.1612656037-1162994308.1612656037  "Endometriosis." Health, John Hopkins Medicine, https://www.hopkinsmedicine.org/health/conditions-and- diseases/endometriosis  Kronemyer, Bob. "How Race/Ethnicity Influences Endometriosis." Contemporary OB/GYN, 22 May 2019, https://www.contemporaryobgyn.net/view/how-raceethnicity-influences-endometriosis  "Endometriosis." US Department of Health and Human Services, Office on Womens Health. https://www.womenshealth.gov/a-z-topics/endometriosis  "Polycystic Ovary Syndrome." US Department of Health and Human Services, Office on Womens Health. https://www.womenshealth.gov/a-z-topics/polycystic-ovary-syndrome
  • 17. Source: AbbVie on Youtube Closing Video