Tuberculosis (TB).

2. human remains
History:-

3. Cytochrome
oxidase
enzyme
flavoprotein
Catalase enzyme
H2O2 → O2 + H2O
O2 + e → H2O + energy
O2 + e → H2O2 + energy

4. Bacilli=Rods slow-growing
Visible growth takes 3 to 8 weeks on solid media.
flat, dry and rough
with irregular edges
T = 30: 37 °C G=15 : 20 hours

5. peptidoglycan
Mycolic acids
Wax-D
Proteins
Lipids
Polysaccharides
Arabinogalactan

6. strong hydrophobic molecules
that form a lipid shell around the organism
affect permeability properties
at the cell surface
Mycolic acid
Characteristic for
Mycobacterium tuberculosis

7. lipids

11. But by

16. 4,200,000 nucleotides

19. inhalation of droplet nuclei
Breathing sneezing
Talking cough

22. Symptoms of tuberculosis
Patients with high loads of the bacteria or
streaks or drops of Blood
in their expelled sputum.
presence of cough lasting three weeks or more.
presence of cavities in the lungs on X rays.
fever for a long duration that is
not explained by any other cause
sweats
General fatigue

25. The drugs must be taken
for up to two years.

30. Susceptibility testing
is important to guide therapy.
For above 50 kg

31. Isoniazid (INH) and Rifampicin (RMP)
Rifampicin (RMP)
Isoniazid(INH),Rifampicin(RMP) & 2nd line drugs

32. alter target site.
phosphorylate, acetylate, or adenylate.
Lipids.
out of the cell.

34. Prevention is bitter than cure

36. Designed & Edited by:
Under Supervision :