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Opioid Withdrawal Attenuation Coctail
1.
Opioid Withdrawal Attenuation Cocktail Acute Withdrawal: Clonidine 0.1mg QID x anticipated length of withdrawal. (Check BP & watch for hypotension) Diarrhea: Hyocosamine 0.125mg every 46 hours PRN Myalgias: Ibuprofen 400mg po QID or Acetamenophen 325mg po Q6hrs Anxiety: Hydroxyzine 25mg po TID Insomnia: Trazodone 50300mg po QHS Nausea: Ondansetron 8mg po BID x anticipated length of withdrawal. (Check QTc) Anticipated Withdrawal As A Part of a Planned Taper: Anxiety: Gabapentin starting at 600 mg TID and titrating up as necessary, max dose 1200mg/TID. Clonidine 0.1mg QID x anticipated length of withdrawal. (Check BP & watch for hypotension) Diarrhea: Loperamide 4mg then 2mg QID Myalgias: Ibuprofen 400mg po QID or Acetamenophen 325mg po Q6hrs Anxiety: Hydroxyzine 25mg po TID Insomnia: Trazodone 50300mg po QHS; Mirtazapine 1530 mg qHS Nausea: Ondansetron 8mg po BID x anticipated length of withdrawal. (Check QTc)
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