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VNUS Workshop Jordan2010
1. VNUS ClosureFast for Treatment of Venous Reflux Dr J.A.Lawson PhD ,vascular surgeon A simple lunch break procedure
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3. Venous Work Environment 1500 3000 1000 H ospital Amstelland Ph lebology Centre Alkmaar Jan van Goyen Clinic Amsterdam Phlebologic Center Alkmaar 3000 Amsterdam
24. Endovenous thermal ablation is an image-guided procedure that uses heat generated by radiofrequency or laser energy to seal off truncal superficial veins, diverting blood flow immediately to nearby deep veins .
30. Crossectomy is obsolete 1,8 % recurrence rate of the junction after 24 months H e always ligated the anterior accessory saphenous vein
31. No Crossectomy preserves physiologic flow through the tributaries 7,7 % of tributaries were refluxing. I n 62 % it was the a nterior accessory saphenous vein
32. Randomized trial comparing high ligation and stripping of the great saphenous vein and endovenous laser ablation (980-nm) using exclusively local tumescent anaesthesia: one year follow-up. Pascal Pronk M.D.¹, Stefanie A Gauw BN¹, Michael C Mooij M.D.¹, Menno TW Gaastra M.D.¹, James Lawson M.D., PhD.¹, Clarissa J van Vlijmen-van Keulen M.D., PhD.¹ ¹ Flebologisch Centrum Oosterwal, Alkmaar S ubmitted for EJVES
66. Pain Following 980-nm Endovenous Laser Ablation and Segmental Radiofrequency Ablation for Varicose Veins: A Prospective Observational Study Shepperd Vascular and Endovascular Surgery, Vol. 44, No. 3, 212-216 (2010
68. RCT comparing laser,foam,stripping and VNUS by Rasmussen ( 2010) L ow pain scores and better QOL with VNUS and Foam sclerotherapy Procedure O cclusion ( %) 2 years T ime to normal F unction ( days) VNUS 93,3 1 EVLT 93,6 4 FOAM 85,0 1 Stripping 96,0 4
72. Anatomic Considerations Insufficiency Both GSV and Anterolateral Thigh Vein ASV GSV GSV GSV GSV ASV ASV ASV VNUS EVLT or Foam Crossectomy VNUS +Foam 7
Dear dr Bozkurt. Ladies and Gentleman am very honored to be with you together in this distinguished institute to share my experience with the VNUS ClosureFast technique for treating Venous Reflux in parients with varicose veins
My name is James lawson. I am vascular surgeon since 1985. I wrote a thesis about the use of umbilical vein as graft material in femoro distal bypass My current research objects are the antithrombotic therapy after vascular surgery, risk factors of atherosclerotic disease and the last couple of years I am very interested in the results of endovenous thermal ablation
This are the hospitals and clinics where a have my practice as a vascular surgeon. This are the numbers of venous procedures that are done at the different locations. Personally I do some 1000 endovenous procedures per year. Most of them are VNUS ablations
My home country is Holland . A small country with 16,6 million inhabitants 384.000 are from Turkish origin. Holland is famous because of his flowers especially the Tulips. A lot of people are thinking that they are typically Dutch. nothing is farther from the truth than that
The tulips are originally coming from Turkey !
Tourist are very fond of our wooden shoes. Actually they are still used by farmers , to keep there foot warm and dry, while working on the wet clayey soil of the farming grounds i
Dutch people are very proud of her Wind Mills as you can see here . They are a big tourist attraction, especially the old ones becaus e the modern ones are extremely efficient but very distractive in our original landscape. One important function especially in the past is to pump the water back to the canals into the sea
Our country is wet and below sea level The reason is that our country is suffering from many depressions from the Atlantic ocean so it is raining most of the year. Another problem is that most of the country is below sea level
The purple colour on the map is showing the area which is below sea level. If the sea level will keep rising in the coming decades a big part of holland will be swallowed up by the sea
That is wh at actually happened in 1953 when after a big storm a big area of the southern part of Holland was flooded.
After that flood there was a urgency to pay more attention to protect the country against the upcoming water. The deltaplan was necessary to close the sea arms. To protect the specific salt water nature around the sea arms Dikes were build with flood doors which were only closed during storms
After that flood there was a urgency to pay more attention to protect the country against the upcoming water. The deltaplan was necessary to close the sea arms. To protect the specific salt water nature around the sea arms Dikes were build with flood doors which were only closed during storms
O n the drawing you see the flood doors. They are very much alike the venous valves in the leg of human beings. You can compare flood with the blood volume which is coming van above because of standing up. The valves are closing.
In these medical situation we call these flood reflux
To threat this reflux of truncal veins vein stripping was the standard of care for nearly a century
But I n the late nineties of the last century Endovenous ablation techniques were invented and became more en more popular
This is my personal time line in venous surgery. As can see more than 3 decades of stripping went by before starting my endovenous career
Why seems the endovenous therapy to be near to an ideal treatment Non invasive and repeatable Office procedure under tumescent anesthesia Safe and less Morbidity Effective in treatment of Reflux Cosmetic acceptable Less postoperative pain No “ sick leave
T o compare evlt which high ligation and stripping we did a randomized trial in our clinic in Alkmaar . The results are published in the european journal of vascular surgery
In the varico trial there were the same clinical results between stripping and evlt procedures.
But we had one disappointment the recovery was actually better with stripping under local anesthesia than evlt
So if we choose for a thermal ablation which one is the best ?
I am are going to be more serious . Steve Jobs was a great admirer of Leonardo da Vinci. He is one of the most famous scientists He recited many times one of his best quotes
Simplicity is the beste sophistication Take that in your mind
With laser, heat is generated by the action of the laser on the chromophore (substance that absorbs the laser light). It is thought that the mechanism of damage to the vein wall is the generation of a steam bubble around the laser tip from the blood still within the vein (boiling blood). This steam then transmits its heat to the vein wall via the high temperature gradient
No it is not . If we study the literature about clinical results , we must always find how they did it
N ot very simple machines who needs regular maintenance
The mechanism by which RF current heats tissue is resistive (or ohmic) heating of a narrow rim of tissue that is in direct contact with the electrode. Deeper tissue planes are then slowly heated by conduction from the small region of volume heating. This real radiofrequency technique we still find this in the RFS catheter for treating perforators. We talk about this later
Then they found out the closurefast catheter. . Radiofrequency was just used to heat a electric coil at the end of the catheter. Heat was transferred directly to the the waal of the vain by conduction. That is simple as that . Because of the conductions it is important to empty the treated vein with abundant tumescent and trendelenburg position
7cm length treated all at once with conductive heating coil No energy delivery during repositioning Energy delivery does not vary by pullback speed Stationary treatment= therapy consistency = excellent vein occlusion efficacy Conclusion: very simple !
The software is guiding you through the process
This is a slide demonstrating the animal histology of ClosureFAST catheter after ablation of goat saphenous veins. Note the complete fibrotic occlusion of the vein. Note also that these slides were taken at different time intervals. Twelve weeks was chosen for ClosureFAST testing because it is a much better indicator of long-term results,
Painscores Closure Plus vs Laser and Stripping
P ainscores shepperd study
Shepperds study: pain medication after treatment
Recovery after treatment: Painscores
In 2009 we did a survey under Dutch customers which perform the VNUS ClosureFast treatment. This are the results
To define a specific set-up in your varicose vein clinic, with dedicated staff and employees, you can reach a high grade of efficacy which makes the procedures cost effective
T h is what a visiting surgeon from Riga Letland thought and said from our Phelebology center in Alkmaar. He is performing 4 cases/ day
The fundamental change that has occurred in the last decade is the move to treat varicose veins away from the operating theater under general anesthesia, towards ambulant, office-based management. This has had cost advantages, freed up expensive theater time, and has improved the convalescent phase for patients
he ClosureRFS Stylet is the only intravascular ablation device specifically cleared by the FDA for the treatment of incompetent perforator veins. This minimally invasive outpatient treatment can be either the primary procedure or an adjunct to saphenous vein ablation with the VNUS ClosureFAST™ catheter
Minimally invasive outpatient procedure which can be performed under local anesthesia in the physician's office Quick patient recovery time, usually returning to work same day Minimal scarring at skin penetration points Temperature-controlled heating at the treatment site
There are only a few publications describing results from the RFS treatment
Finally something about future developments Covidien developed a strategy of becoming a leading partner with interventional radiologists and vascular surgeons. Thats why they building new Vascular Therapies global business unit.” Besides acquisition of several innovative products They want to do more Research and Development of vascular therapies In the pipeline is a shorter coil for the ClosureFast Procedure Thank you very much for your attention