GenTegra produces and markets solutions for stabilizing DNA and RNA in solution, or dried down for long term storage at ambient temperatures, along with bio-banking products for whole blood stabilization and long-term room temperature storage. For instance, our customers add GenTegra RNA immediately upon purifying the RNA and it protects while in liquid form. Once they are done with the sample, they dry it down and the RNA is protected for years. It can be reconstituted for re-sampling, dried down again and re-stored up to 7 times. And it does not require purification as the product is small-molecule based; nothing in the product will interfere with any downstream analysis. See our website at Gentegra.com for more information or contact us for a seminar at 925-461-3010.

1. LLC
Redefining Ambient Stabilization
February 2014
1 | Proprietary and GenTegra Confidential | 2/11/2014

2. As a researcher, the value of your results is our most important
priority. Allowing you to protect your biosamples, from the earliest
stage possible, through long-term storage is what we offer.
RNA can be protected immediately after being isolated and purified,
through short and long term storage.
DNA can be protected either without purification for biobanking, or
as purified for transport and storage.
2 | Proprietary and GenTegra Confidential | 2/11/2014

3. Product Overview
GenTegra DNA & GenTegra RNA product lines
Stabilization and storage of
purified/extracted DNA & RNA
GenPlates & Archives
High density stabilization
and storage of blood &
biosamples
GenSolve
High yield recovery of
stored blood and
biosamples on FTA paper
3 | Proprietary and GenTegra Confidential | 2/11/2014

4. Products
GenTegra-RNA
• Immediate and long-term protection of RNA
GenTegra-DNA
• Long-Term protection of DNA
GenTegra is the only truly DRY state
storage method available, providing
a better and more risk free storage.
4 | Proprietary and GenTegra Confidential | 2/11/2014

5. GenTegra-RNA
RNA: unstable as it is being purified
GenTegra-RNA: immediate protection for the RNA while being
processed
When dried the RNA is given long term protection at ambient
temperature
Target users:
Epigenomics, Proteomics
Targeted sequencing,
NGS in general,
Cancer genetics, etc.
5 | Proprietary and GenTegra Confidential | 2/11/2014

6. GenTegra-DNA
DNA is more stable than RNA and is relatively safe in liquid for
normal processing times.
GenTegra-DNA provides long-term stabilization of the DNA when the
solution is dried and stored at ambient temperature with data for 9
years of storage and accelerated data equivalent to 30 years.
Target users:
NGS in general
epigenomics
targeted sequencing
cancer genetics
etc.
6 | Proprietary and GenTegra Confidential | 2/11/2014

7. Products
GenPlates
• Long-term, high density storage of blood, blood products and biosamples
GenSolve
• High yield extraction of biosamples from FTA and other paper
Archive cabinets
• High density dry GenPlate storage at ambient temperature
7 | Proprietary and GenTegra Confidential | 2/11/2014

8. GenPlates & GenSolve Products
GenPlates
• High density method of storing blood (and biologicals) of FTA paper
• Universally accepted FTA disc of 6 mm diameter
• Guthrie cards, other papers
• GenTegra offers 5 configurations for user; 1, 3, 6, 12, 24 regions
• All in a 384 half-height SBS microplate
• Really a choice of how many replicates the user needs/wants
Target Markets
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Small genome project (State of Alaska Salmon project)
Targeted human studies
Species projects for endangered animals
Ag and vet studies
8 | Proprietary and GenTegra Confidential | 2/11/2014

9. GenPlates
1 Region, 384 elements
3 Region, 96 elements
6 Region, 40 elements
12 Region, 16 elements
24 Region, 4 elements
9 | Proprietary and GenTegra Confidential | 2/11/2014
Every GenPlate is barcoded
and hermetically sealed in a
silvered mylar bag.
GenPlates shelf life is
essentially unlimited before
opening and decades after
opening if properly stored in
low humidity environment.

10. GenTegra Products
Personal Archive cabinet
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High density convenient GenPlate storage at ambient temperature
Holds 1176 GenPlates or half that number of standard microplates
Dehumidifier and Barcode scanner included
GenConnect software for sample tracking, optional
10 | Proprietary and GenTegra Confidential | 2/11/2014

11. Products
GenSolve
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High yield extraction of biosamples from FTA and other paper
No commercial competitive product
Generic protocols for DO-IT-YOURSELF
GenSolve significantly improves quantity of extracted DNA
11 | Proprietary and GenTegra Confidential | 2/11/2014

12. Redefining Ambient Stabilization
12 | Proprietary and GenTegra Confidential | 2/11/2014

13. LLC
Contacts: James Nelson, PhD
Bruce Jamieson
+1 925-461-3010
+1 408-813-2344
JamesN@gentegra.com
BruceJ@gentegra.com
www.gentegra.com
13 | Proprietary and GenTegra Confidential | 2/11/2014