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                                                 Pinning Down Tumor Cells’ Resistance to Therapy

                                                                                    Dr. Diehn is working to break down        professor in the Department of
                                                                                    the cellular defenses of leukemia and     Radiation Oncology and Institute for
                                                                                    solid cancers.                            Stem Cell Biology and Regenerative
                                                                                                                              Medicine at Stanford University. Last
                                                                                    His research with a breast tumor          year he contributed to the discovery of
                                                                                    model has suggested that the key to       human bladder cancer stem cells and
 C
                                                                                    eradicating a cancer is to find and       published evidence of treatment
 M                                                                                  destroy all of the cancer’s stem cells.   resistance mechanisms in solid tumor
 Y
                                                                                    The grant allowed Dr. Diehn protected     cancer stem cells.
                                                                                    time to investigate mechanisms
CM
                                                                                    within those cells that resist chemo-     “In addition to funding the work itself,
MY                                                                                  therapy and radiation therapy.            I believe that the R&E grant signifi-
                                                                                                                              cantly strengthened my CV because it
CY
                                                 Maximilian Diehn, M.D., Ph.D.
                                                                                    Better understanding of these mecha-      documented that I could successfully
CMY
                                                 Department of Radiation Oncology
                                                 Stanford University                nisms, fueled by Dr. Diehn’s research,    compete for external grant funding,”
 K
                                                 R&E Grant Recipient                may help physicians deliver targeted      said Dr. Diehn. “I think this program
                                                                                    treatment that can wipe out a cancer      does exactly what it sets out to do.”
                                                                                    for good.
                                                                                                                              Innovations like Dr. Diehn’s are the
                                                                                    Dr. Diehn used his promising results      real building blocks for medical
                                                                                    to pursue funding from the National       breakthroughs that will deliver better
                                                                                    Institutes of Health and private          care to patients.
                                                                                    foundations. Today, he’s an assistant



                                                 r&e grants are creating the future. make it a guarantee. donate today.

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Re Rad Onc Inside

  • 1. Inside RadOnc.eps 1 4/7/10 4:21 PM Pinning Down Tumor Cells’ Resistance to Therapy Dr. Diehn is working to break down professor in the Department of the cellular defenses of leukemia and Radiation Oncology and Institute for solid cancers. Stem Cell Biology and Regenerative Medicine at Stanford University. Last His research with a breast tumor year he contributed to the discovery of model has suggested that the key to human bladder cancer stem cells and C eradicating a cancer is to find and published evidence of treatment M destroy all of the cancer’s stem cells. resistance mechanisms in solid tumor Y The grant allowed Dr. Diehn protected cancer stem cells. time to investigate mechanisms CM within those cells that resist chemo- “In addition to funding the work itself, MY therapy and radiation therapy. I believe that the R&E grant signifi- cantly strengthened my CV because it CY Maximilian Diehn, M.D., Ph.D. Better understanding of these mecha- documented that I could successfully CMY Department of Radiation Oncology Stanford University nisms, fueled by Dr. Diehn’s research, compete for external grant funding,” K R&E Grant Recipient may help physicians deliver targeted said Dr. Diehn. “I think this program treatment that can wipe out a cancer does exactly what it sets out to do.” for good. Innovations like Dr. Diehn’s are the Dr. Diehn used his promising results real building blocks for medical to pursue funding from the National breakthroughs that will deliver better Institutes of Health and private care to patients. foundations. Today, he’s an assistant r&e grants are creating the future. make it a guarantee. donate today.