1. Comprehensive Genetic Analysis
Breast Cancer
TM
deCODE Breast Cancer
deCODE Breast CancerTM identifies 7 widely
replicated genetic variants (SNPs) that are
associated with increased risk of developing
common breast cancer, independent of family
history. These SNPs contribute to the incidence
of anestimated 60 percent of all breast cancers.
It is a novel, noninvasive, DNA-based reference
laboratory test that offers physicians the
opportunityto begin screening or initiate early
treatment in those who are at increased risk.
BRCA 1 and BRCA 2 Common
Mutation
BRCA 1 a n d BRCA 2 a r e t h e p r ima r y g e n e s
responsible for the hereditary breast cancers. Statistics
sugge s t tha t up to 10% of br e a s t c anc e r s a r e
hereditary. Patients who have a strong family history
of early-onset breast cancer in multiple first-degree
relatives are often tested for the common mutations in
the BRCA 1 and BRCA 2 genes.
.
BreastSafe® Test OncotypeDX Breast Cancer Assay
Oncotype DX ® is a diagnostic assay that quantifies the likelihood of
This special logic-based profiling test improves the
sensitivity of breast cancer diagnosis by identifying breast cancer recurrence in women with newly diagnosed, early stage
the lumps at a very early stage before any symptoms breast cancer. It is validated for use in breast cancer patients whose
appear. disease is:
Her 2 Gene Amplification l Newly diagnosed
Women with HER2-positive breast cancer (not passed to l Stage I or II
the family) have a more aggressive disease, greater l Node-negative
likelihood of recurrence, poorer prognosis, and decreased l Estrogen receptor-positive
survival compared to women with HER2-negative breast
cancer. It is thus an important diagnosis for the treatment of Oncotype DX offers clinical experience information for newly
breast cancer. diagnosed women who are post-menopausal and have node positive,
estrogen receptor positive breast cancer and who will be treated with
tamoxifen.
EASTERN BIOTECH
& l i f e s c i e n c e s
Eastern Biotech & Life Sciences
P.O.Box 212671, Dubai, UAE. Tel: +971 4 369 2061 Fax: +971 4 363 1923
email:info@easternbiotech.com visit: www.easternbiotech.com