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STRIKE THE RIGHT BALANCE WHILE PRESCRIBING 
PSYCHOTROPICS TO CHILDREN IN DEVELOPING 
ECONOMIES 
Devashish Konar MD Consultant Psychiatrist 
Mental Health Care Centre, Kolkata, India 
1 
WPA 2014 Madrid, Spain
DISCLOSURE 
I don’t have any financial disclosures to make. 
Literature whenever quoted source has been mentioned. 
2
THE CHALLENGE 
• Mental health issues are being recognised more and at an earlier age. 
• Issue is alarming, at the same time recognising them early is good for 
the child. 
• Treating and maintaining them in the society with 
trained-manpower- crunch remain the main challenge in developing 
economies. 
Frellick 2014 
3
CAN’T DO IT ALONE 
• The shortage of clinician with specialised training in assessing and 
managing the treatment of patients with mental disorder is a major 
barrier to providing adequate services in low and middle income 
countries (Saraun & Dua 2009, Saxena 2007 Kakuma et al 2011). 
• Current models that rely on mental health professionals to deliver 
care are unsuitable for low and middle income countries, where 
number of mental health professional in lacking (Patel 2009). 
Raynaud 2014 
4
TAKE HELP 
A shift to collaborative care to emphasise training, supervision, and 
tertiary care while transferring the bulk of direct service delivery to 
community health workers or primary care professionals who would 
receive specific training and supervision in mental health is needed. 
(Patel 2009) 
Raynaud 2014 
5
ADJUSTING WITH REAL LIFE SITUATION 
• Inadequate trained personnel remains the fore concern for 
developing economies. 
• So managing the work load with constraint of resources makes the 
work difficult. 
• Clinical work-up has to be brief. 
• Therapeutic sessions may have to be cut down to counselling. 
• Medication may become important part of treatment. 
• Judicious prescribing and never, ever, over-prescribing should be the 
mantra. 
6
PSYCHOTHERAPY VIS-A-VIS PHARMACOTHERAPY 
• Targeted psychotherapy by appropriately trained mental health 
clinicians remains the safest and most efficacious treatment modality 
for many psychiatric disorders in the pediatric population. 
• Medication is only one piece of treatment plan. 
• Relying on it may be the need if other trained personnel are not 
available. 
• And then, if we know that psychotherapy is the safest and most 
efficacious treatment, training has to be taken up urgently. Culture 
specific models need to be tested and popularised without delay. 
Szigethy 2014 
7
FACILITATING EARLIER PSYCHIATRIC CONSULTATION 
• One of the most important points is facilitation of earlier psychiatric consultation. 
• Too often, referral for psychiatric evaluation is only considered in the context of a significant 
worsening of clinical status, such as onset of suicidal ideation, or when a patient or family is 
beginning to lose hope and turn to medications “as a last resort.” 
• It is important for providers to inform patients and families that waiting for symptoms to become 
more severe may decrease the probability of response or remission of symptoms. 
So, on the one hand they need to be educated to come early for assessment and on the other 
hand you need to restrict yourself in prescribing medication unnecessarily or at the drop of hat. 
Trivedi 2012 
8
IT IS IMPORTANT TO IDENTIFY EARLY 
• Childhood and adolescence is a period of extraordinary biological, 
psychological and social growth. 
• However, at such times, individuals are also vulnerable to disruptions 
of healthy development. 
• 50% of all adult psychiatric disorders have manifested by age 14, 
with 75% manifesting by age 24. 
• Two thirds of pediatric-onset psychiatric disorders are moderate or 
severe, and most continue into adulthood. 
• So early identification and appropriate treatment of psychiatric 
disorders as early as possible to preserve healthy development and to 
reduce individual suffering and societal burden is important. 
Rapoport 2013 
9
INVESTIGATION: IF NOT ADEQUATE, BE OPTIMUM 
• Adequate investigation may not be feasible due to financial 
constraints but important ones cannot be omitted and safety 
concerns may never be downplayed. 
• So taking hints from clinical presentation regarding adverse effects 
may be more important in the context of developing economies. 
10
SERVICE DELIVERY MODEL HAS TO BE INDIGENOUS 
• With limited trained child psychiatrists, training other general 
psychiatrists and even pediatricians and family physicians may be 
more important than in developed economies. 
• Sensitisation about diagnostic clarity, proper drug selection, some 
minimal counselling and psycho-education skills and identifying 
adverse effects are the minimum targets that we need to foray into. 
• Copying western models may not work across the countries and 
cultures. 
• Chances of being biased in diagnosis and treatment in favour of 
multinational pharmaceuticals may be a serious trap. 
• Culture specific models need to be worked up. 
11
TRANSMITTING INFORMATION IN THIS COLLABORATIVE MODEL 
HAS TO BE SPECIFICALLY VERY RESTRICTED AND SIMPLE 
Antipsychotics 
Risperidone 
Aripiprazole 
Quetiapine 
Antidepressants 
Fluoxetine 
Escitalopram 
Sertralin 
Mood-stabilizers 
Lithium 
Divalproex 
Drug for ADHD 
Methyphenydate 
Atomoxetine 
12
SOCIAL PRESSURE MAY DECIDE TREATMENT OPTION 
• Usually acute crisis brings the child in contact with services. 
• In these instances, parents and school personnel may demand rapid 
results. 
• Waiting lists for psychosocial treatment and longer periods to initial 
symptom control may further diminish the attractiveness of 
psychotherapy. 
• Psychopharmacology may be in demand. 
Rapaport 2013 
13
CHILD PSYCHOPHARMACOLOGY BECOMING MORE IMPORTANT 
• There have been a number of groundbreaking developments in the 
management of pediatric psychiatric disorders. 
• No more exclusive reliance on psychological and behavioral 
interventions, psychopharmacologic advances have provided 
important biological management tools for severe pediatric 
psychiatric disorders. 
• The advent of modern psychopharmacology has further informed the 
efficacy and tolerability of major psychotropic drug classes in youth. 
• This progress has been facilitated by regulatory agencies encouraging 
and, more recently, requiring adequate studies of pharmacologic 
agents in pediatric patients. 
Rapoport 2013 
14
NEED TO HAVE ONE’S OWN RESEARCH AGENDA 
• Research even though may seem a luxury in developing economies, 
there is a definite role of it for having country specific, culture specific 
and need based models of delivery. 
• Copying western models blindly may neither serve the purpose nor 
address the problem adequately. 
15
16

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STRIKE THE RIGHT BALANCE WHILE PRESCRIBING PSYCHOTROPICS TO CHILDREN IN DEVELOPING ECONOMIES

  • 1. STRIKE THE RIGHT BALANCE WHILE PRESCRIBING PSYCHOTROPICS TO CHILDREN IN DEVELOPING ECONOMIES Devashish Konar MD Consultant Psychiatrist Mental Health Care Centre, Kolkata, India 1 WPA 2014 Madrid, Spain
  • 2. DISCLOSURE I don’t have any financial disclosures to make. Literature whenever quoted source has been mentioned. 2
  • 3. THE CHALLENGE • Mental health issues are being recognised more and at an earlier age. • Issue is alarming, at the same time recognising them early is good for the child. • Treating and maintaining them in the society with trained-manpower- crunch remain the main challenge in developing economies. Frellick 2014 3
  • 4. CAN’T DO IT ALONE • The shortage of clinician with specialised training in assessing and managing the treatment of patients with mental disorder is a major barrier to providing adequate services in low and middle income countries (Saraun & Dua 2009, Saxena 2007 Kakuma et al 2011). • Current models that rely on mental health professionals to deliver care are unsuitable for low and middle income countries, where number of mental health professional in lacking (Patel 2009). Raynaud 2014 4
  • 5. TAKE HELP A shift to collaborative care to emphasise training, supervision, and tertiary care while transferring the bulk of direct service delivery to community health workers or primary care professionals who would receive specific training and supervision in mental health is needed. (Patel 2009) Raynaud 2014 5
  • 6. ADJUSTING WITH REAL LIFE SITUATION • Inadequate trained personnel remains the fore concern for developing economies. • So managing the work load with constraint of resources makes the work difficult. • Clinical work-up has to be brief. • Therapeutic sessions may have to be cut down to counselling. • Medication may become important part of treatment. • Judicious prescribing and never, ever, over-prescribing should be the mantra. 6
  • 7. PSYCHOTHERAPY VIS-A-VIS PHARMACOTHERAPY • Targeted psychotherapy by appropriately trained mental health clinicians remains the safest and most efficacious treatment modality for many psychiatric disorders in the pediatric population. • Medication is only one piece of treatment plan. • Relying on it may be the need if other trained personnel are not available. • And then, if we know that psychotherapy is the safest and most efficacious treatment, training has to be taken up urgently. Culture specific models need to be tested and popularised without delay. Szigethy 2014 7
  • 8. FACILITATING EARLIER PSYCHIATRIC CONSULTATION • One of the most important points is facilitation of earlier psychiatric consultation. • Too often, referral for psychiatric evaluation is only considered in the context of a significant worsening of clinical status, such as onset of suicidal ideation, or when a patient or family is beginning to lose hope and turn to medications “as a last resort.” • It is important for providers to inform patients and families that waiting for symptoms to become more severe may decrease the probability of response or remission of symptoms. So, on the one hand they need to be educated to come early for assessment and on the other hand you need to restrict yourself in prescribing medication unnecessarily or at the drop of hat. Trivedi 2012 8
  • 9. IT IS IMPORTANT TO IDENTIFY EARLY • Childhood and adolescence is a period of extraordinary biological, psychological and social growth. • However, at such times, individuals are also vulnerable to disruptions of healthy development. • 50% of all adult psychiatric disorders have manifested by age 14, with 75% manifesting by age 24. • Two thirds of pediatric-onset psychiatric disorders are moderate or severe, and most continue into adulthood. • So early identification and appropriate treatment of psychiatric disorders as early as possible to preserve healthy development and to reduce individual suffering and societal burden is important. Rapoport 2013 9
  • 10. INVESTIGATION: IF NOT ADEQUATE, BE OPTIMUM • Adequate investigation may not be feasible due to financial constraints but important ones cannot be omitted and safety concerns may never be downplayed. • So taking hints from clinical presentation regarding adverse effects may be more important in the context of developing economies. 10
  • 11. SERVICE DELIVERY MODEL HAS TO BE INDIGENOUS • With limited trained child psychiatrists, training other general psychiatrists and even pediatricians and family physicians may be more important than in developed economies. • Sensitisation about diagnostic clarity, proper drug selection, some minimal counselling and psycho-education skills and identifying adverse effects are the minimum targets that we need to foray into. • Copying western models may not work across the countries and cultures. • Chances of being biased in diagnosis and treatment in favour of multinational pharmaceuticals may be a serious trap. • Culture specific models need to be worked up. 11
  • 12. TRANSMITTING INFORMATION IN THIS COLLABORATIVE MODEL HAS TO BE SPECIFICALLY VERY RESTRICTED AND SIMPLE Antipsychotics Risperidone Aripiprazole Quetiapine Antidepressants Fluoxetine Escitalopram Sertralin Mood-stabilizers Lithium Divalproex Drug for ADHD Methyphenydate Atomoxetine 12
  • 13. SOCIAL PRESSURE MAY DECIDE TREATMENT OPTION • Usually acute crisis brings the child in contact with services. • In these instances, parents and school personnel may demand rapid results. • Waiting lists for psychosocial treatment and longer periods to initial symptom control may further diminish the attractiveness of psychotherapy. • Psychopharmacology may be in demand. Rapaport 2013 13
  • 14. CHILD PSYCHOPHARMACOLOGY BECOMING MORE IMPORTANT • There have been a number of groundbreaking developments in the management of pediatric psychiatric disorders. • No more exclusive reliance on psychological and behavioral interventions, psychopharmacologic advances have provided important biological management tools for severe pediatric psychiatric disorders. • The advent of modern psychopharmacology has further informed the efficacy and tolerability of major psychotropic drug classes in youth. • This progress has been facilitated by regulatory agencies encouraging and, more recently, requiring adequate studies of pharmacologic agents in pediatric patients. Rapoport 2013 14
  • 15. NEED TO HAVE ONE’S OWN RESEARCH AGENDA • Research even though may seem a luxury in developing economies, there is a definite role of it for having country specific, culture specific and need based models of delivery. • Copying western models blindly may neither serve the purpose nor address the problem adequately. 15
  • 16. 16

Editor's Notes

  1. Medscape Medical News Mental Health Disabilities in Children Up 21% in 10 Years Marcia Frellick August 18, 2014 Childhood Disability Rate Increases Over Decade, Study Finds American Psychiatric news
  2. From Research to Practice in Child & Adolescent Mental Health by Jean Philippe Raynaud, Mental Health & Global Agenda (Book) 2014 by Anne E. Page no-6
  3. From Research to Practice in Child & Adolescent Mental Health by Jean Philippe Raynaud, Mental Health & Global Agenda (Book) 2014 by Anne E. Page no-8
  4. Utility of CBT of Children, Adolescents in Era of Accountable Care Eva Szigethy, 2014 Psychiatric News Update
  5. CHILD AND ADOLESCENT PSYCHITRIC CLINICS OF North America, consulting editor Harsh K. Trivedi, MD, Oct 2012-Vol 21- Number 4 (Page no-710)
  6. World Psychitry jun 2013; 12(2): 127-128, published online jun4, 2013 PMCID; PMC3683259
  7. World Psychitry jun 2013; 12(2): 127-128, published online jun4, 2013 PMCID; PMC3683259 by Rapaport
  8. J. Rapoport World Psychitry jun 2013; 12(2): 127-128, published online jun4, 2013 PMCID; PMC3683259