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JDRF Cure Diabetes Research Cures Treatments

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The Juvenile Diabetes Research Foundation (JDRF) aims to cure, treat, and prevent diabetes through funding research. It has funded over $1 billion in research over 39 years to find disease-modifying drugs and devices. JDRF partners with industry, academia, patients, and other organizations to fund early-stage, translational, and clinical research. Its highest priorities include beta cell therapies, immune therapies, artificial pancreas devices, and therapies to prevent complications.

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Juvenile Diabetes Research Foundation (JDRF) www.jdrf.org
JDRF: Mission and General Strategy To find a cure for diabetes and its complications Proactively accelerate the discovery , developmen t, and delivery of disease-modifying drugs and devices to better treat and cure diabetes and its complications
Diabetes Market Landscape ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
JDRF: Support ,[object Object],[object Object],[object Object],[object Object],[object Object]
JDRF: Partners JDRF Venture Capital Industry People with Type 1 Diabetes Providers, Educators Academia Funders: NIH, Government, Foundations FDA Payers JDRF
JDRF: Support ,[object Object],[object Object]
JDRF: Diabetes Stage-Specific Focus Treat Prevent Prevent Treat Cure Established Diabetes Recent Onset Diabetes At-Risk
JDRF: Support ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
JDRF: R&D Strategy JDRF’s Role: To advance IP and product development by “de-risking”, increasing value, and filling gaps Patients ,[object Object],[object Object],Clinical Development Translational Research Basic Research
JDRF: Industry Partners- 1 EU FP Funding (through Phase I ) Immune Therapies Beta Cell Therapies
JDRF: Industry Partners- 2 Glucose Control Complication Therapies
GNF-JDRF Partnership: Filling a Critical Gap Deliver novel IND candidates for out-licensing or co-development with Novartis or other pharma  cell survival -Housey -GNF ,[object Object],[object Object], cell survival -Kafman -Nadler -Others ,[object Object],[object Object],[object Object],[object Object],[object Object],Reprogram. -Hecksher- Sorensen -Schreiber XOMA-052 -Survival Reprogram -Herrera -Ferber -Kay/Grompe -Bouwens -RFA pending Progenitor cells -Sander/ Cirulli -Ferrer -Bonner-Weir - Bouwens Cell Target Path- way Target ID Lead ID Lead Develop Lead Optim EIH Enable Clinical Proof of concept ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object], cell survival -Johnson -Zick-Others PPI/DPPIVi -Rabinovitch Gastrin therapy -Transition Leading Pharma Partners Leading Academic Partners
JDRF: Organizational Leadership ,[object Object],[object Object],[object Object],[object Object]
JDRF: Summary/Key Points ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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JDRF Cure Diabetes Research Cures Treatments

  • 1. Juvenile Diabetes Research Foundation (JDRF) www.jdrf.org
  • 2. JDRF: Mission and General Strategy To find a cure for diabetes and its complications Proactively accelerate the discovery , developmen t, and delivery of disease-modifying drugs and devices to better treat and cure diabetes and its complications
  • 3.
  • 4.
  • 5. JDRF: Partners JDRF Venture Capital Industry People with Type 1 Diabetes Providers, Educators Academia Funders: NIH, Government, Foundations FDA Payers JDRF
  • 6.
  • 7. JDRF: Diabetes Stage-Specific Focus Treat Prevent Prevent Treat Cure Established Diabetes Recent Onset Diabetes At-Risk
  • 8.
  • 9.
  • 10. JDRF: Industry Partners- 1 EU FP Funding (through Phase I ) Immune Therapies Beta Cell Therapies
  • 11. JDRF: Industry Partners- 2 Glucose Control Complication Therapies
  • 12.
  • 13.
  • 14.
  • 15. Q&A

Editor's Notes

  1. Gap Slide – describe key area JDRF is playing. Pat, are there any IDDP opportunities for later stage targets (i.e. IRS2?)