Oral Pathology I Third Year

1. Red blue lesion
By
Abdulrahman al sulaiman
Saleh al abbas
Khalid al ahmary
Tariq al mutair

2. Why

3. Intravascular
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Congenital
Reactive
Neoplasm
Metabolic
immunologic

5. congenital:
haemangioma
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Increased in number of capillaries
Benign tumours of infancy
Characterized by:
Growth phase with endothelial cell proliferation
of large (cavernous) or small (capillary) vascular
channels
Diagnosed at first 8 weeks of life
3 female vs. 1 male

6. .Cont
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Site : most common in head and neck
Shape : pale macula with thread like
telangieclasis
Superficial skin lesion appear raised and
bosselated
Firm and rubbery to palpation

7. treatment
Spontaneous involution during early childhood
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8. Congenital :
vascular malformation
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Structural anomaly of blood vessel without
endothelial proliferation
Present at birth and persist throughout life and
grow with individual

9. .Cont
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Capillary form :
Part wine spot are common
Later in life lesion darken & becomes nodular
due to ectasia

10. .Cont
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Venous form :
Blue in colour
Compressible
Swelling associated with increase venous
pressure

11. .Cont
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Anteriovenous form :
Persistent direct arterial & venous
communication :
Palpable thrill
Overlying skin is hot to touch
pain, bleeding and skin ulceration

12. Sturge-weber syndrome
Encephalotrigeminal angiomatosis
- Venous malformation involving leptomeninges of
cerebral cortex
- assocciated facial lesion known as port-wine stain
- vascular lesion of encephalotrigeminal angiomatosis
may extend to oral cavity
- neurologic effects of encephalotrigeminal angiomatosis
may include:
mental nerve
seizure disorder

13. Rendu-Osler Weber Syndrom
Hereditary hemorrhagic telangiectasia
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Multiple hemangiomas
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Autosomal dominant transmitted manner
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Abnormal vascular dilation of terminal vessels
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Clinical features :
Age : appear early in life and persist through adulthood .
Shape : red macules or papules .
Site : face, chest and oral mucosa .

14. .Cont
Complications :
Intranasal lesions.
Intraoral lesions .
Chronic low-level bleeding .
 Histopathology :
Capillary and cavernous types similar to other
hemangiomas .
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15. treatment
Of vascular lesion are
Surgical
Laser therapy
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17. Varix
&
other vascular malformations
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It is a type of acquired vascular malformation .
A fairly-common condition of older people .
Distended blood vessels are observed on the
lingual tongue surface .
Syndrome : lingual varices .

18. Pyogenic Granuloma
Etiology
Injury or stimulus (EX : calculus ) .
Hormonal changes .
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This well lead to :
Modified gingival reparative mechanism .
Prolifration of CT rich with capillaries .

19. .Cont
Clinical features :
Shape : red broad based mass .
Age : any age .
Sex : female > male
Site : gingiva
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20. treatment
Remove of the etiological factor
calculus,hormonal)
surgical remove
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)

21. Periphral giant cell granuloma
Etiology:
.Unusual hyperplastic CT response to injury
.Leads to : reparative process containing multinucleated giant cells
 Clinical features:
Site : gingiva
Origin : PDL
. Shape : red blue , broad based mass and may ulcerate
Age : any age
Sex : female > male
 Radiographically : result in erosion of cortical bone
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22. treatment
Remove of the etiological factor
calculus,hormonal)
surgical remove
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)

23. Scarlet Fever
Systemic bacterial infection can lead to capillary damage .
 Clinically :
Pharyngitis , Tonsillitis, fever, lymphadenpathy and
headache
Red face
Tongue cover with white coat & enlarged fungiform
papilla (strawberry tongue)
After the white coat is lost (raspberry tongue)

25. (Erythroplakia ( Red Patch
Significantly higher incidence than leukoplakia
Lesion appear as well defined red patch .
Site : floor of the mouth, tongue and retromolar mucosa
Age : 50:70
Sex : no predilection
 Histopathology :
- Epithelial dysplasia
- Relative reduction in keratin production
- Increase in vascularity
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26. Treated with surgery if possible

27. Neoplasms:
kaposi’s sarcoma
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Etiopathogenesis:
Human harpesvirus 8
Kaposi’s sarcoma herpesvirus
Aids associated

28. .Cont
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Clinical features :
Classic form ( indolent form & poor prognosis )
Older male
Multifocal reddish brown nodules
Affect skin and lower extremities

29. cont
Endomic form :
Common in black population
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Immunodeficiency form ( rapid aggressive & poor
prognosis ):
Multifocal skin lesion not limited to extremities
Oral and lymph node lesion are common
Involve visceral organs
Younger age group
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30. .cont
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Histopathology features :
Hypercellular foci
Defined vascular channels
Extarvasated RBCs
Later may superficially resemble
pyogenic granulomas

32. Metabolic
vitamin b complex deficiencies
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Etiopathogenesis :
Decreased intake of vitamin b
Clinical feature :
Oral changes pain, burning sensation ,lip
fissuring …est
Keratitis of the eye
Scaly dermatitis on nasolabial area

33. Vitamin b12 deficiency
((pernicious anaemia
Clinical feature :
Adult
Weakness .pallor, shortness of breath and fatigue
Headache, dizziness
Nausea , diarrhoea& stomalitis
Oral manifestation :
Glossitis due to atrophy of the papillae
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34. Plummer vinson syndrome
((iron deficiency
Clinical feature :
Weakness , pallor, shortness breath ,brittle nails &
hair atrophy of upper GIT and glossitis
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35. Burning mouth syndrome
Etiologic :
Micro organisms fungi, bacteria
Xerostomia
Vit . B . Iron& zink deficiency
Diabetes mellitus
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36. Clinical feature
Middle age
Altered taste
Tongue is most involvement site
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38. Plasma cell gingivitis
Etiology :
Chewing gum may provide allergic reaction .
Hypersensitivity reaction to certain dietary components .
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Clinical features :
Common in adults, occasionally affect children .
No sex predilection .
Sudden onset, no systemic complains .
Fairly red attached gingiva but not ulcerated .
Burning tongue, lip & mouth .
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39. .Cont
Histopathology :
- Spongioutic epithelium .
- Mixed inflammatory cell infiltrate .
- Densely prominent capillaries in lamina propria .
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41. EXTRAVASCULAR LESIONS
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PETECHIAE & ECCHYMOSIS
Etiology :
Intraoral, due to blood disease .
 leukemia
 platelets defect
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hemophillia and related disorders .
Trauma .

42. .Cont
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Clinical features :
Color depend on duration (red-blue-purple).
Soft tissue lesions occur in traumatic areas .
Hemorrhagic lesions occur spontaneously .