This document contains statistics on different types of assisted reproduction treatments in Romania for 2012, including: 1) In vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), frozen embryo transfer (FET), and intrauterine insemination (IUI) treatments using partner donations resulted in over 4,600 couples treated and over 5,400 treatment cycles. 2) Treatments using non-partner sperm donations involved over 200 couples and 240 cycles but resulted in no pregnancies or births. 3) Treatments using non-partner egg donations involved 16 cycles which resulted in 5 clinical pregnancies and 1 live birth. 4) Embryo donation treatments involved 12 recipients and

1. ROMANIA
ART - with partner donation Treatment type
IUI IVF ICSI FET (1) other
N° of couples treated 1.948 1.187 1.276 85 125 4.621
N° of initiated cycles (started with the intention to treat) 2.596 1.214 1.313 93 189 5.405
- Fresh cycles (2) 924 1.305 123 2.352
- Frozen cycles (2) 283 199 53 39 574
N° of IUI or aspirations cycles or embryo (or zygotes) thawed cycles (for FET) 489 179 328 109 70 1.175
N° of oocytes collected 10574 9445 1.166 21.185
N° of oocytes inseminated/injected 7998 9041 568 17.607
N° of oocytes frozen during IVF or ICSI 20 20
N° of embryos (or zygotes(3)) created or thawed (for FET) 6801 6318 150 55 13.324
N° of embryos (or zygotes) frozen 989 309 20 1.318
N° of embryos (or zygotes) transfers (ET) 2.235 2.043 100 406 4.784
N° of embryos or zygotes transferred 416 630 212 1.258
N° of clinical pregnancies (4) 255 457 422 15 79 1.228
N° of live births (deliveries) 113 158 115 3 18 407
N° of babies borne 109 180 144 3 21 457
Total N° of frozen oocytes stored at 31.12 24:00 13 10 23
Total N° of frozen embryos/zygotes stored at 31.12 24:00 273 228 501
SPERM OOCYTES
EMBRYOS/
ZYGOTES
95 16 79
31 79
44 42
0 0 0
Intra EU
Extra EU
166 0 0
Intra EU 166
Extra EU
ART with non partner SPERM donation Treatment type
IUI IVF ICSI FET (1) other
N° of couples treated 153 54 8 8 3 226
N° of initiated cycles (started with the intention to treat) 174 44 9 8 4 239
- Fresh cycles (2) 54 9 4 67
- Frozen cycles (2) 8 8
N° of IUI or aspirations cycles or embryo (or zygotes) thawed cycles (for FET) 0
N° of oocytes collected 0
N° of oocytes inseminated/injected 0
N° of oocytes frozen during IVF or ICSI 0
N° of embryos (or zygotes(3)) created or thawed (for FET) 0
N° of embryos (or zygotes) frozen 0
N° of embryo (or zygotes) transfers (ET) 0
N° of embryos or zygotes transferred 0
N° of clinical pregnancies (4) 0
N° of live births deliveries 0
N° of babies borne 0
Total N° of frozen oocytes stored at 31.12 24:00 0
Total N° of frozen embryos/zygotes stored at 31.12 24:00 0
ART with non partner OOCYTE donation IVF ICSI FET other TOTAL
N° of Cycles IVF or ICSI or FET for recipients 16 16
N° total of oocytes allocated 172 6 178
N° of oocytes mixed/injected 130 130
N° of embryos or zygotes created or thawed (FET) 140 140
N° of embryos / zygotes frozen 76 76
N° of embryos or zygotes transfers (ET) 24 24
N° of embryos or zygotes transferred 71 71
N° of clinical pregnancies 5 5
N° of live births (deliveries) 1 1
N° of babies borne 1 1
Total N° of frozen embryos/zygotes stored at 31.12 24:00 14 14
ART with non partner OOCYTES AND SPERM donation IVF ICSI FET other TOTAL
N° of Cycles IVF or ICSI or FET for recipients 0
N° total of oocytes allocated 0
N° of oocytes mixed/injected 0
N° of embryos or zygotes created or thawed (FET) 0
N° of embryos / zygotes frozen 0
N° of embryos or zygotes transfers (ET) 0
N° of embryos or zygotes transferred 0
N° of clinical pregnancies 0
N° of live births (deliveries) 0
N° of babies borne 0
Total N° of frozen embryos/zygotes stored at 31.12 24:00 0
ART with embryo donation FET
N° of recipients 12
N° of embryos donated 51
N° of embryo transfers (ET) 9
N° of embryos transferred 23
N° of clinical pregnancies 1
N° of live births (deliveries)
N° of babies borne
ARTCENTER
(1) FET: Frozen thawed embryo transfer cycles
(2) Fresh cycles and Frozen cycles : need for definition. The definition of this item is not available in the Glossary of WHO and ICMART.
(3) In case of zygote freezing
(4) a pregnancy diagnosed by ultrasonographic visualization of one or more gestational sacs or definitive clinical signs of pregnancy. It includes ectopic pregnancy.
Note: Multiple gestational sacs are counted as one clinical pregnancy (ICMART WHO glossary)
TOTAL
N° of donors (with actual donation)
N° of donations (sperm/oocytes collections)
N° of oocytes, embryos, zygotes donated
N° of sperm straws, oocytes, embryos/zygotes distributed in a foreign country (export)
N° of sperm straws, oocytes, embryos/zygotes received from a foreign country (import)
FOR DEFINITION SEE THE GLOSSARY ON ART TERMINOLOGY, 2009
The International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) Revised Glossary on ART Terminology, 2009
Journal article - Fertility and Sterility, Vol. 92, No. 5, November 2009
ART DATA - activity year 2012
TOTAL
NON PARTNER DONATION ACTIVITIES