Data centralization entails the concept of gathering and referencing the data from a single point of view. This presentation highlights 14 advantages of data centralization.

1. ADVANTAGES OF DATA
CENTRALIZATION IN CLINICAL
TRIALS

2. Effective cross-functional
communications between
data management, statistics
and medical writing
#1

3. Centralized study
documentation facilitates
more efficient editing, version
control, auditing and
information access
#2

4. A central warehouse for clinical
and safety data avoids having to
keep track of who has what and
facilitates annual safety updates
to regulatory authorities
#3

5. A sponsor can have one web-
based portal to access
progress reports on all
studies
#4

6. Only one Master Services
Agreement for data services
required
#5

7. The Serious Adverse Event
[SAE] reconciliation effort is
eased when the Case Report
Form [CRF] data and the safety
data are managed by the same
organization
#6

8. A project-specific medical writer can
produce all required regulatory and
clinical documents [such as protocols
and clinical study reports], and also
assist in publication
planning, preparation and
management of all publication
requirements
#7

9. A single medical writing team
with an experienced lead
reviewer will ensure consistency
across all clinical and regulatory
documentation as well as
publications
#8

10. Sponsors and regulatory
authorities benefit from a
straight forward audit trail that
follows a similar path for all
trials
#9

11. Post centralization data
management operations are
more efficient and less
costly, with higher data quality
#10

12. Facilitates information
transfer across the network
and the research community
resulting in efficient data
analysis
#11

13. Centralized treatment
allocation can help prevent
statistical biases and
treatment imbalances in multi
center clinical trials
#12

14. Data can be easily integrated
and visualized to support
study teams or management
decisions, resulting in a faster
way of sending links to any
source in the system
#13

15. Centralized system allows for
sending automated updates
regarding various aspects of
study conduct
#14