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MARYCAIREMD
THE PATH TO
WELLNESS
THROUGH BIG DATA
23andMe
Genetic Genie
Tree of Life
Past medical history
Family history
Symptom documentation
Biomarkers
Inflammatory marke...
25%
/MaryCaireMD
@MaryCaireMD
/in/MaryCaireMD
The Path to Wellness Through Big Data
Big Data. Shared. Simply. Securely.
Roy Wilds
Director of Product Management
PHEMI S...
PHEMI COPYRIGHT 2016
Physiological Diagnosis
Trial and ErrorTherapy
Systemic Delivery
Late Stage Care
Ineffective Therapy
...
PHEMI COPYRIGHT 2016
Vancouver-based not-for-profit organization
Vision: Introduce an individualized approach to preventiv...
PHEMI COPYRIGHT 2016
MYCO provides:
 a comprehensive, molecular-level health monitoring program for preventive
medicine t...
PHEMI COPYRIGHT 2016
Molecular You Co. uses PHEMI to advance preventive and curative healthcare
• Early warning system
• P...
PHEMI COPYRIGHT 2015
The Data Dilemma in Precision Medicine
Share and Protect?
Data available
analysis, insights,
and new ...
Copyright PHEMI Systems20
How do I share data
for secondary use
without compromising privacy,
security, and governance?
PHEMI COPYRIGHT 2016
PHEMI Central Big Data Warehouse
OmicsSpreadsheetsTextSystemsDatabase SensorsImages
Custom
Applicatio...
PHEMI COPYRIGHT 2015
Addressing Precision Medicine Challenges
22
Collect
Index and catalog
for findability
Protect
and Sha...
PHEMI COPYRIGHT 2016
Metadata Billions of Assets
23
PHEMI COPYRIGHT 2016
User Attributes
Access Control Based on User Attributes
24
PHEMI COPYRIGHT 2016
Protect
Zero Trust to Read Data
25
PHEMI Central’s Policy Enforcement
Engine reduces the risk of data...
PHEMI COPYRIGHT 2016
Each user (or application) sees only data they are authorized to see
26
Example
Applications
Privacy
...
PHEMI COPYRIGHT 2016
Architecture Components
Privacy, Security, and Governance “out of the box”
• Distributed, scalable ba...
PHEMI COPYRIGHT 2016
Questions?
Roy Wilds, PhD
Director of Product Management, PHEMI Systems
rwilds@phemi.com
28
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
The Path to Wellness through Big Data
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The Path to Wellness through Big Data

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The Path to Wellness through Big Data

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The Path to Wellness through Big Data

  1. 1. MARYCAIREMD THE PATH TO WELLNESS THROUGH BIG DATA
  2. 2. 23andMe Genetic Genie Tree of Life Past medical history Family history Symptom documentation Biomarkers Inflammatory markers Hormonal levels Cortisol levels Microbiome testing Nutritional analysis Metabolic markers Toxicity testing Lipid testing Vitamin/mineral reporting Vital signs Wearables
  3. 3. 25%
  4. 4. /MaryCaireMD @MaryCaireMD /in/MaryCaireMD
  5. 5. The Path to Wellness Through Big Data Big Data. Shared. Simply. Securely. Roy Wilds Director of Product Management PHEMI Systems rwilds@phemi.com
  6. 6. PHEMI COPYRIGHT 2016 Physiological Diagnosis Trial and ErrorTherapy Systemic Delivery Late Stage Care Ineffective Therapy Unsustainable Healthcare Costs Patient Lacks Knowledge And Power Present Practice Molecular Diagnosis Therapy Based on Molecular Diagnosis Targeted Delivery Preventive Care Patient Specific, Effective Treatment Reduced Waste Patient Empowerment Personalized Medicine Personalized Medicine: A Massive Change In Medical Practice Driven By New Technologies That Characterize Individuals at the Molecular Level TECHNOLOGY 15
  7. 7. PHEMI COPYRIGHT 2016 Vancouver-based not-for-profit organization Vision: Introduce an individualized approach to preventive and curative healthcare based on the molecular makeup of the individual and their disease  More effective and safer therapeutics  Better matching of treatment to disease  More effective preventive medicine; patient empowerment  More efficient healthcare  Identification of new drug targets and therapeutics BenefitsMolecular “Omic” Analyses 16
  8. 8. PHEMI COPYRIGHT 2016 MYCO provides:  a comprehensive, molecular-level health monitoring program for preventive medicine to detect early disease and monitor response to therapy.  a molecular analysis program to stratify disease to better match treatment to the individual patient THE MOLECULAR YOU PROGRAM • Whole exome sequencing up front • Every four months: • Proteomic analysis of blood (>200 proteins) • Metabolomic analysis of blood (>200 metabolites) • Microbiomic analysis of colon (>1,000 bacteria) • Download continuous monitoring of vital signs (heart rate etc.) • Bioinformatic analysis of data (early signs of disease, response to therapy etc.) • Consultation with healthcare professional to interpret data 17 Molecular You Corporation: Precision Health
  9. 9. PHEMI COPYRIGHT 2016 Molecular You Co. uses PHEMI to advance preventive and curative healthcare • Early warning system • Prevent, delay, mitigate • Quarterly molecular screening • Grow to 25,000 patients • 15+ varied data sources • Integrate “omics” with • clinical data • Longitudinal study • Rich research Precision Medicine 21 Life Sciences Institute
  10. 10. PHEMI COPYRIGHT 2015 The Data Dilemma in Precision Medicine Share and Protect? Data available analysis, insights, and new services Analytics Applications 19
  11. 11. Copyright PHEMI Systems20 How do I share data for secondary use without compromising privacy, security, and governance?
  12. 12. PHEMI COPYRIGHT 2016 PHEMI Central Big Data Warehouse OmicsSpreadsheetsTextSystemsDatabase SensorsImages Custom Applications Advanced Analytics Data Science • Flexible, agile data repository for multi-structured data • Support advanced analytics, data science and new services • Govern, manage and control access to protect privacy and manage data sharing • Publish data marts • Scale as your data and users grow • Deploy on premise or in the cloud 21
  13. 13. PHEMI COPYRIGHT 2015 Addressing Precision Medicine Challenges 22 Collect Index and catalog for findability Protect and Share Privacy, Security & Governance Curate and Transform Analytics-ready
  14. 14. PHEMI COPYRIGHT 2016 Metadata Billions of Assets 23
  15. 15. PHEMI COPYRIGHT 2016 User Attributes Access Control Based on User Attributes 24
  16. 16. PHEMI COPYRIGHT 2016 Protect Zero Trust to Read Data 25 PHEMI Central’s Policy Enforcement Engine reduces the risk of data breach by enforcing rules universally and consistently for each user and data element.
  17. 17. PHEMI COPYRIGHT 2016 Each user (or application) sees only data they are authorized to see 26 Example Applications Privacy Controlled Data Warehouse
  18. 18. PHEMI COPYRIGHT 2016 Architecture Components Privacy, Security, and Governance “out of the box” • Distributed, scalable base • PHEMI Central • Coordinates and manages all processes • Abstracts and simplifies distributed concepts • Audits and manages data and interactions 27 HDP Ambari Spark Map-Reduce Kafka PHEMI Central Accumulo YARN
  19. 19. PHEMI COPYRIGHT 2016 Questions? Roy Wilds, PhD Director of Product Management, PHEMI Systems rwilds@phemi.com 28

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