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Digital Re-print - July | August 2010
Fusarium mycotoxins – What’s all the fuss about?



   Grain & Feed Milling Technology is published six times a year by Perendale Publishers Ltd of the United Kingdom.
   All data is published in good faith, based on information received, and while every care is taken to prevent inaccuracies,
   the publishers accept no liability for any errors or omissions or for the consequences of action taken on the basis of
   information published.
   ©Copyright 2010 Perendale Publishers Ltd. All rights reserved. No part of this publication may be reproduced in any form
   or by any means without prior permission of the copyright owner. Printed by Perendale Publishers Ltd. ISSN: 1466-3872




                           www.gfmt.co.uk                                                                                       NEXT PAGE
PUB85x254-T5X            28/01/10    14:22     Page 1
                                                                                                      Fusarium mycotoxins                          Feature                         Feature                   Fusarium mycotoxins



        Fusarium mycotoxins                                                                                                                                                   Percentage
                                                                                                                                                                              of UK wheat
                                                                                                                                                                              harvest
                                                                                                                                                                              samples
                                                                                                                                                                                                            was a major issue for the      in the south east of


                      – What’s all the fuss about?                                                                                                                            exceeding                     industry, but particularly     the country.
                                                                                                                                                                              legal limits for              for bran production as              The situation
                                                                                                                                                                              DON and ZON                   the majority of UK wheat       for barley and
                                                                                                                                                                            Year      DON ZON               would have produced            oats is different.
          If the grower does not know the intended end use (of grain), he should not assume it is for animal feed;
                                                                                                                                                                                                            bran greater than 100ppb.           For       barley,
               “feed wheat” in the grain trade is used as a quality specification rather than a defined end-use
                                                                                                                                                                                                                 As a result of these      fusarium mycotoxin
                                                                                                                                                                            2001       0.4       0.7
                                                                                                                                                                                                            high levels and the dif-       levels have been
                                                                                                                                                                            2002       1.7       0.6
                                                  by Prof Simon Edwards, Harper Adams University College, UK                                                                                                ficulty in supply of bran      consistently low
                                                                                                                                                                            2003       2.4       1.2        that would allow produc-       with only a few
                                                                                                                                                                            2004       5.5      11.3        tion of high-fibre finished    samples exceeding



    F
          usarium mycotoxins are toxic                    extent of the fusarium mycotoxin issue there- concentrations exist in small and damaged grains                    2005       1.5       1.2        products within limits the     the ZON limit as
          chemicals produced by a group                   fore fluctuates each season depending on rainfall and in chaff and dust, so cleaning can give some                                                European Commission            a result of delayed
                                                                                                                                                                            2006       0.0       0.3
          of fungi called Fusarium. These                 in early and late summer.                              reduction, but this is highly dependent on the qual-                                       set a one-year derogation      harvests. For oats,
                                                                                                                                                                            2007       4.0       2.7
    fungi produce mycotoxins when they                        The HGCA has developed a fusarium risk ity of the grain consignment before cleaning.                                                          for high-fibre breakfast       DON and ZON
    infect cereals, resulting in a disease                assessment to allow growers to assess the risk             Higher concentrations also exist in the bran           2008      13.1      28.6        cereals and wheat bran as      levels have been
    called fusarium head blight (see photo).              of exceeding the legal limits for fusarium myco- compared to the flour fractions, so milling results              2009       2.0       5.3        an intermediary product        consistently low but
    Fusarium infects the crop during flowering            toxins in harvested wheat.                             in an increase in mycotoxins in the bran fraction                                          of 100ppb and 125ppb           oats have relatively
    in early June and symptoms develop                        The assessment is based on the known and a decrease in the flour fractions compared                                ZON respectively which ended in October 2009.             high levels of two                                There are other
                                                                                                                                                                                                                                                                                             ways to bind
    about a month later in early July.                    risks and includes both agronomic factors (loca- to the original grain.                                                     There is much less of an issue for fusarium          other closely related
                                                          tion, rotation, cultivation, varietal resistance and       Experimental results have shown that the dis-               mycotoxins in feed.                                       toxins, HT2 and T2.
        Ten years ago farmers and processors were
    largely unaware of what fusarium mycotoxins
                                                          fungicide use) and rainfall at key stages of crop tribution of DON and ZON is different within
                                                          development (flowering in early June) and pre- the grains. DON is highly water soluble and can
                                                                                                                                                                                      There are guideline limits of 8000ppb DON
                                                                                                                                                                                 and 2000ppb ZON for wheat intended for
                                                                                                                                                                                                                                           There is currently no
                                                                                                                                                                                                                                           legislation for these                             mycotoxins…

                                                                                                                                                                                                                                                                                             T5X
    were, let alone aware of the potential issues.        harvest (August).                                      therefore move within the grains if repeatedly                  animal feed.                                              mycotoxins but
        But things have changed drastically since             The risk assessment is a Crop Assurance rehydrated (eg during a wet harvest), whereas                                   These levels are very rare in UK cereals. There      legislation is under
    then and mycotoxins are now one of the top            Scheme requirement and the score is                                                                                    are lower limits for finished feeds and these vary        discussion and could
    issues for wheat quality. In 2006, the European       included on the grain passport. If the score is          Table 1: Maximum mycotoxin limits                             for different livestock due to differences in sensi-      be an issue of oat
    Commission set legislative maximum limits for         high then a DON test should be performed                 for wheat and wheat products                                  tivity, with lowest limits set for pig feed.              processors depend-
    fusarium mycotoxins, deoxynivalenol (DON)
    and zearalenone (ZON) in unprocessed cereals
                                                          to check the level present.
                                                              At the moment, National Association              Product
                                                                                                                                                        Mycotoxin (ppb)
                                                                                                                                                         DON         ZON
                                                                                                                                                                                      Ruminants and poultry appear more tolerant to
                                                                                                                                                                                 fusarium mycotoxins although there were reports
                                                                                                                                                                                                                                           ing on limits set.
                                                                                                                                                                                                                                                HGCA contin-
                                                                                                                                                                                                                                                                                             much more than
    and finished products.                                of British and Irish Millers (Nabim) request                                                                           of poor hatchability in poultry after the 2008 harvest.   ue to fund research                               a Toxinbinder
        The Home Grown Cereals Authority                  a DON test is completed for each consign-                                                                                                                                        at Harper Adams,
                                                                                                               Unprocessed wheat                        1250          100
    (HGCA) and Food Standards Agency (FSA)                ment of wheat delivered to mills irrespec-                                                                               An evolving disease                                     Fera and TAG to
                                                                                                               Grain and mill fractions for
    awarded two research grants to Harper Adams           tive of the risk assessment score. This will
                                                                                                               human consumption
                                                                                                                                                         750           75              It is important to note that fusarium head          improve the fusari-                               T5X has four major actions :
    University College to identify the extent of          be reviewed after the start of the 2010                                                                                  blight is an evolving disease and continues             um risk assessment.
    fusarium mycotoxins in UK cereals and the             intake and maybe relaxed based on early              Wheat-based products                      500           50          to change. Fusarium graminearum, the main               This includes more                                T5X binding components have been
    impact of agronomy in 2001.                           season results.                                      Wheat-based products for infants          200           20          producer of DON and ZON, is increasing in               precise modelling                                 selected in a sophisticated “in vivo”
        These five-year projects identified the varying       One of the trade issues raised by the            Note: Limits for barley and oats are as above except                Northern Europe and is currently spreading up           of weather data                                   model. Mycotoxins do not pass through
    extent to which UK cereals suffer from myco-          mycotoxin legislation is that grain is sold          DON limit for unprocessed oats is 1750ppb                           the eastern side of the UK. From 2001-2005,             and the use of early                              the intestinal wall.
    toxin contamination and the “Good Agricultural        based on a quality specification of milling or                                                                           levels of fusarium mycotoxins were consistently         in-field monitoring
                                                                                                                                                                                                                                                                                             T5X stimulates the production of specific
    Practice” that can be adopted to minimise the         feed wheat and yet, feed wheat may be sold on ZON has low water solubility and appears to                                low in Scotland, but in 2009, the first wheat sam-      of fusarium inocu-
                                                                                                                                                                                                                                                                                             natural detoxication enzymes to catalyse
    risk from fusarium mycotoxins.                        for human consumption.                                 largely remain where it was produced, which is                    ples above legal limits for DON were identified         lum in the spring.
                                                                                                                                                                                                                                                                                             the elimination of the mycotoxins.
        Unfortunately, the project identified that            Growers consider that if grain is sold as feed mainly in the bran fraction.
    the fusarium mycotoxins concentration is highly       wheat then it is destined for animal feed and              Results from the 2008 harvest agreed with                                                                                                                               T5X powerful antioxidants inhibit free
    dependent on weather with rainfall at key             does not require a fusarium risk assessment or previous findings that DON is produced in early                           Related companies                                                                                         radicals and prevent cells' membrane
    growth stages of the crop being critical. The         mycotoxin test.                                        summer during Fusarium head blight infection                                                                                                                                from degradation.
                                                                                                                                                                                   Calibre Control
                                                              In reality, if the grower does not know the and ZON is produced in late summer as the                                5-6 Asher Court Lyncastle                                                                                 T5X stimulates the non specific immune
Good Agricultural Practice to                             intended end use, he should not assume it is crop ripens.                                                                Way, Appleton, Warrington,                                                                                system to strengthen animals
reduce fusarium mycotoxins                                for animal feed; “feed wheat” in the grain trade           This results in a change in the mycotoxin                     WA4 4ST, United Kingdom
                                                          is used as a quality specification rather than a profile depending on when in the summer we                                Tel: +44 1925 860401
  - Use Fusarium resistant varieties
                                                          defined end-use.                                       have rainfall.                                                      Email: info@calibrecontrol.com
  - Avoid maize as previous crop                                                                                                                                                     Web: www.calibrecontrol.com
                                                                                                                     A wet delayed harvest results in a greater
  - Plough to bury crop debris; if using                  Robust molecules                                       increase in ZON than DON. In this scenario,                       Perstorp Performance Additives
    min-till, chop/mix as much as possible                    Fusarium mycotoxins, DON and ZON are as experienced in 2004 and 2008, we have                                        Industrieweg 8
  - Use a high rate of a recommended                      robust molecules and there is very little reduc- more wheat exceeding the ZON limit than the                             Waspik, 5165 NH
    head blight fungicide at correct                      tion during processing, even with high tempera- DON limit. The 2008 was the worst wet harvest                            The Netherlands                                                                              Additives & difference
    timing (early flowering)                              tures for example, baking.                             experienced for many years and we had close                         Tel: +31 416 317700
                                                                                                                                                                                     Fax: +31 416 316698
  - Avoid lodging and harvest delays                          The main reduction achieved during processing to 30 percent of the harvested UK wheat crop                                                                                                                    a brand of the   B.P. 394 - 56 009 VANNES Cedex - FRANCE
                                                                                                                                                                                     Email: info@perstorpfeed.com
                                                          is partitioning during cleaning and milling. Higher exceeded the legal limit of 100ppb ZON. This                           Web: www.perstorpfeed.com                                                                      group    Neovia@evls.net

    30 | July - august 2010                                                                                                Grain  &feed millinG technoloGy                         Grain  &feed millinG technoloGy                                PREVIOUS PAGE     NEXT PAGE                                     July - august 2010 | 31
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 August                     2010                                                                    •	 See	the	full	issue
                        •	 Mycotoxin	
                           testing:
                        	 ready for this year’s
                           harvest?
                                                                                                    •	   Visit	the	GFMT	website
                                                                           In this issue:

                        •	 Added	value	                            •     Technical design


                                                                                                    •	   Contact	the	GFMT	Team
                           by		Flour	Heat	                                and equipment
                           Treatment                                      - Key to improving
                                                                            feed quality and
                                                                                    nutrition
                                                                   • Factors affecting
                                                                             pelleting
                        •	 Making	Feed	                                   and energy
                             Pellets                                     consumption
                                                                   •                Fusarium
                                                                                   mycotoxins
                                                                               – What’s all the
                                                                                                    •	   Subscribe	to	GFMT
                                                                                  fuss about?


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Fusarium mycotoxins – What’s all the fuss about?

  • 1. Digital Re-print - July | August 2010 Fusarium mycotoxins – What’s all the fuss about? Grain & Feed Milling Technology is published six times a year by Perendale Publishers Ltd of the United Kingdom. All data is published in good faith, based on information received, and while every care is taken to prevent inaccuracies, the publishers accept no liability for any errors or omissions or for the consequences of action taken on the basis of information published. ©Copyright 2010 Perendale Publishers Ltd. All rights reserved. No part of this publication may be reproduced in any form or by any means without prior permission of the copyright owner. Printed by Perendale Publishers Ltd. ISSN: 1466-3872 www.gfmt.co.uk NEXT PAGE
  • 2. PUB85x254-T5X 28/01/10 14:22 Page 1 Fusarium mycotoxins Feature Feature Fusarium mycotoxins Fusarium mycotoxins Percentage of UK wheat harvest samples was a major issue for the in the south east of – What’s all the fuss about? exceeding industry, but particularly the country. legal limits for for bran production as The situation DON and ZON the majority of UK wheat for barley and Year DON ZON would have produced oats is different. If the grower does not know the intended end use (of grain), he should not assume it is for animal feed; bran greater than 100ppb. For barley, “feed wheat” in the grain trade is used as a quality specification rather than a defined end-use As a result of these fusarium mycotoxin 2001 0.4 0.7 high levels and the dif- levels have been 2002 1.7 0.6 by Prof Simon Edwards, Harper Adams University College, UK ficulty in supply of bran consistently low 2003 2.4 1.2 that would allow produc- with only a few 2004 5.5 11.3 tion of high-fibre finished samples exceeding F usarium mycotoxins are toxic extent of the fusarium mycotoxin issue there- concentrations exist in small and damaged grains 2005 1.5 1.2 products within limits the the ZON limit as chemicals produced by a group fore fluctuates each season depending on rainfall and in chaff and dust, so cleaning can give some European Commission a result of delayed 2006 0.0 0.3 of fungi called Fusarium. These in early and late summer. reduction, but this is highly dependent on the qual- set a one-year derogation harvests. For oats, 2007 4.0 2.7 fungi produce mycotoxins when they The HGCA has developed a fusarium risk ity of the grain consignment before cleaning. for high-fibre breakfast DON and ZON infect cereals, resulting in a disease assessment to allow growers to assess the risk Higher concentrations also exist in the bran 2008 13.1 28.6 cereals and wheat bran as levels have been called fusarium head blight (see photo). of exceeding the legal limits for fusarium myco- compared to the flour fractions, so milling results 2009 2.0 5.3 an intermediary product consistently low but Fusarium infects the crop during flowering toxins in harvested wheat. in an increase in mycotoxins in the bran fraction of 100ppb and 125ppb oats have relatively in early June and symptoms develop The assessment is based on the known and a decrease in the flour fractions compared ZON respectively which ended in October 2009. high levels of two There are other ways to bind about a month later in early July. risks and includes both agronomic factors (loca- to the original grain. There is much less of an issue for fusarium other closely related tion, rotation, cultivation, varietal resistance and Experimental results have shown that the dis- mycotoxins in feed. toxins, HT2 and T2. Ten years ago farmers and processors were largely unaware of what fusarium mycotoxins fungicide use) and rainfall at key stages of crop tribution of DON and ZON is different within development (flowering in early June) and pre- the grains. DON is highly water soluble and can There are guideline limits of 8000ppb DON and 2000ppb ZON for wheat intended for There is currently no legislation for these mycotoxins… T5X were, let alone aware of the potential issues. harvest (August). therefore move within the grains if repeatedly animal feed. mycotoxins but But things have changed drastically since The risk assessment is a Crop Assurance rehydrated (eg during a wet harvest), whereas These levels are very rare in UK cereals. There legislation is under then and mycotoxins are now one of the top Scheme requirement and the score is are lower limits for finished feeds and these vary discussion and could issues for wheat quality. In 2006, the European included on the grain passport. If the score is Table 1: Maximum mycotoxin limits for different livestock due to differences in sensi- be an issue of oat Commission set legislative maximum limits for high then a DON test should be performed for wheat and wheat products tivity, with lowest limits set for pig feed. processors depend- fusarium mycotoxins, deoxynivalenol (DON) and zearalenone (ZON) in unprocessed cereals to check the level present. At the moment, National Association Product Mycotoxin (ppb) DON ZON Ruminants and poultry appear more tolerant to fusarium mycotoxins although there were reports ing on limits set. HGCA contin- much more than and finished products. of British and Irish Millers (Nabim) request of poor hatchability in poultry after the 2008 harvest. ue to fund research a Toxinbinder The Home Grown Cereals Authority a DON test is completed for each consign- at Harper Adams, Unprocessed wheat 1250 100 (HGCA) and Food Standards Agency (FSA) ment of wheat delivered to mills irrespec- An evolving disease Fera and TAG to Grain and mill fractions for awarded two research grants to Harper Adams tive of the risk assessment score. This will human consumption 750 75 It is important to note that fusarium head improve the fusari- T5X has four major actions : University College to identify the extent of be reviewed after the start of the 2010 blight is an evolving disease and continues um risk assessment. fusarium mycotoxins in UK cereals and the intake and maybe relaxed based on early Wheat-based products 500 50 to change. Fusarium graminearum, the main This includes more T5X binding components have been impact of agronomy in 2001. season results. Wheat-based products for infants 200 20 producer of DON and ZON, is increasing in precise modelling selected in a sophisticated “in vivo” These five-year projects identified the varying One of the trade issues raised by the Note: Limits for barley and oats are as above except Northern Europe and is currently spreading up of weather data model. Mycotoxins do not pass through extent to which UK cereals suffer from myco- mycotoxin legislation is that grain is sold DON limit for unprocessed oats is 1750ppb the eastern side of the UK. From 2001-2005, and the use of early the intestinal wall. toxin contamination and the “Good Agricultural based on a quality specification of milling or levels of fusarium mycotoxins were consistently in-field monitoring T5X stimulates the production of specific Practice” that can be adopted to minimise the feed wheat and yet, feed wheat may be sold on ZON has low water solubility and appears to low in Scotland, but in 2009, the first wheat sam- of fusarium inocu- natural detoxication enzymes to catalyse risk from fusarium mycotoxins. for human consumption. largely remain where it was produced, which is ples above legal limits for DON were identified lum in the spring. the elimination of the mycotoxins. Unfortunately, the project identified that Growers consider that if grain is sold as feed mainly in the bran fraction. the fusarium mycotoxins concentration is highly wheat then it is destined for animal feed and Results from the 2008 harvest agreed with T5X powerful antioxidants inhibit free dependent on weather with rainfall at key does not require a fusarium risk assessment or previous findings that DON is produced in early Related companies radicals and prevent cells' membrane growth stages of the crop being critical. The mycotoxin test. summer during Fusarium head blight infection from degradation. Calibre Control In reality, if the grower does not know the and ZON is produced in late summer as the 5-6 Asher Court Lyncastle T5X stimulates the non specific immune Good Agricultural Practice to intended end use, he should not assume it is crop ripens. Way, Appleton, Warrington, system to strengthen animals reduce fusarium mycotoxins for animal feed; “feed wheat” in the grain trade This results in a change in the mycotoxin WA4 4ST, United Kingdom is used as a quality specification rather than a profile depending on when in the summer we Tel: +44 1925 860401 - Use Fusarium resistant varieties defined end-use. have rainfall. Email: info@calibrecontrol.com - Avoid maize as previous crop Web: www.calibrecontrol.com A wet delayed harvest results in a greater - Plough to bury crop debris; if using Robust molecules increase in ZON than DON. In this scenario, Perstorp Performance Additives min-till, chop/mix as much as possible Fusarium mycotoxins, DON and ZON are as experienced in 2004 and 2008, we have Industrieweg 8 - Use a high rate of a recommended robust molecules and there is very little reduc- more wheat exceeding the ZON limit than the Waspik, 5165 NH head blight fungicide at correct tion during processing, even with high tempera- DON limit. The 2008 was the worst wet harvest The Netherlands Additives & difference timing (early flowering) tures for example, baking. experienced for many years and we had close Tel: +31 416 317700 Fax: +31 416 316698 - Avoid lodging and harvest delays The main reduction achieved during processing to 30 percent of the harvested UK wheat crop a brand of the B.P. 394 - 56 009 VANNES Cedex - FRANCE Email: info@perstorpfeed.com is partitioning during cleaning and milling. Higher exceeded the legal limit of 100ppb ZON. This Web: www.perstorpfeed.com group Neovia@evls.net 30 | July - august 2010 Grain &feed millinG technoloGy Grain &feed millinG technoloGy PREVIOUS PAGE NEXT PAGE July - august 2010 | 31
  • 3. Content from the magazine is available to view free-of-charge, both as a full online magazine on our website, and as an archive of individual features on the docstoc website. LINKS This digital Re-print is part of the July | August 2010 edition of Grain & Feed Milling Technology magazine. Please click here to view our other publications on www.docstoc.com. August 2010 • See the full issue • Mycotoxin testing: ready for this year’s harvest? • Visit the GFMT website In this issue: • Added value • Technical design • Contact the GFMT Team by Flour Heat and equipment Treatment - Key to improving feed quality and nutrition • Factors affecting pelleting • Making Feed and energy Pellets consumption • Fusarium mycotoxins – What’s all the • Subscribe to GFMT fuss about? A subscription magazine for the global flour & feed milling industries - first published in 1891 To purchase a paper copy of the magazine, or to subscribe to the paper edition please contact our Circulation and Subscriptions Manager on the link adove. INFORMATION FOR ADVERTISERS - CLICK HERE Article reprints All Grain & Feed Milling Tecchnology feature articles can be re-printed as a 4 or 8 page booklets (these have been used as point of sale materials, promotional materials for shows and exhibitions etc). If you are interested in getting this article re-printed please contact the GFMT team for more information on - Tel: +44 1242 267707 - Email: jamest@gfmt.co.uk or visit www.gfmt.co.uk/reprints www.gfmt.co.uk PREVIOUS PAGE