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Y Kromozom Mikrodelesyonu
İnfertilite tanısı konulan bazı çiftlerde genetik
incelemelerinin yapılması gerekmektedir. Sperm
testi sonucu azospermi veya oligospermli
hastaların Y kromozom mikrodelesyon testini
yaptırmaları önemlidir.
www.spermtesti.com.tr
0 212 451 16 61
Sağlıklı bir erkek birey 46 XY kromozom yapısına sahiptir. Bu yapıda
bulunan Y kromozomu erkek cinsiyetini tayin etmektedir.Y koromozomu
üzerinde bulunan AZF bölgesi sperm üretiminde doğrudan ilişkilidir. Sperm
testi sonucu semende hiç spermin bulunmaması (Azospermi ) durumunda
çiftlerin çocuk sahibi olabilmeleri için öncelikle erkek bireyin testislerinden
cerrahi işlemle sperm elde etmek gerekmektedir.
www.spermtesti.com.tr
0 212 451 16 61
Bu AZF bölgelerindeki delesyonlar yani eksilmeler
infertiliteye (kısırlık) yol açmaktadır. AZF a, AZF b, AZF
c bölgelerindeki eksilmelerin tespit edilmesi cerrahi
girişimler açısından çok önemlidir. Eğer AZF a ve AZF b
bölgesinde delesyon (eksilme ) varsa hastadan sperm
elde etme şansı yoktur ve yapılan cerrahi girişimler
gereksizdir.
www.spermtesti.com.tr
0 212 451 16 61

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Y kromozom mikrodelesyonu

  • 1. Y Kromozom Mikrodelesyonu İnfertilite tanısı konulan bazı çiftlerde genetik incelemelerinin yapılması gerekmektedir. Sperm testi sonucu azospermi veya oligospermli hastaların Y kromozom mikrodelesyon testini yaptırmaları önemlidir. www.spermtesti.com.tr 0 212 451 16 61
  • 2. Sağlıklı bir erkek birey 46 XY kromozom yapısına sahiptir. Bu yapıda bulunan Y kromozomu erkek cinsiyetini tayin etmektedir.Y koromozomu üzerinde bulunan AZF bölgesi sperm üretiminde doğrudan ilişkilidir. Sperm testi sonucu semende hiç spermin bulunmaması (Azospermi ) durumunda çiftlerin çocuk sahibi olabilmeleri için öncelikle erkek bireyin testislerinden cerrahi işlemle sperm elde etmek gerekmektedir. www.spermtesti.com.tr 0 212 451 16 61
  • 3. Bu AZF bölgelerindeki delesyonlar yani eksilmeler infertiliteye (kısırlık) yol açmaktadır. AZF a, AZF b, AZF c bölgelerindeki eksilmelerin tespit edilmesi cerrahi girişimler açısından çok önemlidir. Eğer AZF a ve AZF b bölgesinde delesyon (eksilme ) varsa hastadan sperm elde etme şansı yoktur ve yapılan cerrahi girişimler gereksizdir. www.spermtesti.com.tr 0 212 451 16 61