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General Data
• 病歷號碼:21717159
• 年齡:48
• 性別:男
• 職業:無
• 種族:臺灣
• 婚姻:已婚
Chief Complaint
• General weakness for one week
– DDX
– AEIOU TIPs
Underlying disease
• Hx of pancreatitis
• T2DM
Underlying disease
• Pancreatitis at 2015/05 complicated with ARDS, necrotizing pancreatitis,
abdominal compartment syndrome
– s/p necrosectomy + drainage
• T2DM, diagnosed 2015/07, by OHA / Insulin, but poor compliance
– 2017 ~ 2019/08 : no medication record
– 2017/10/12 HbA1C=10.9%
Present illness
Abdominal pain
Poor appetite, nausea, thirsty sensation
Dyspnea, progressed for 2 weeks
Decreased urine amount
There was no fever, no chillness, no chest pain, no productive cough, nor limbs edema
Personal History
• Person Hx : Alcoholism
• Alcohol : 藥酒(Alc. 20~30%) 300cc/day for 10+ years
Smoking : 1PPD for 10+ years
Betelnut : 400$ for 10+ years
Physical Examination
• T:35.9 P:124 R:18 SBP:124 DBP:82 E:4 V:5 M:6
• Height : 164 cm BW: 51 kg BMI:19
• General appearance : ill, alochol smell
• Conscious : clear Pupil size : 3+/3+
• HEENT not anemic, not icteric
• throat- not injected
• Neck no jugular enlargement
• no lymphadenopathy
• Chest: BS clear
• Heart : RHB , no murmur
• Abdomen soft and flat
• no tenderness
• no rebound pain
• bowel sound : normoactive
• Mcburney point : negative
• Murphy sign : negative
• Extremities: free movable, no edema
lab
Temperature ℃ 37
pH 7.097
pCO2 mmHg 14.6
pO2 mmHg 126.7
HCO3 mmol/L 4.4
TCO2 mmol/L 4.8
ABE mmol/L -23.1
SBE mmol/L -25.3
SBC mmol/L 8.5
SAT % 98
檢驗項目 單位 1081113
血液組(CBC)
WBC 1000/uL 19.1
RBC million/uL 4.26
Hemoglobin g/dL 14
Hematocrit % 40.8
MCV fL 95.8
MCH pg/Cell 32.9
MCHC g/dL 34.3
RDW % 13.2
Platelets 1000/uL 327
Segment % 89.5
Lymphocyte % 4.8
Monocyte % 5
Eosinophil % 0.2
Basophil % 0.5
BUN (B) mg/dL 24.6
Creatinine(B) mg/dL 1.87
Na mEq/L 139
K mEq/L 5.1
Cl mEq/L 85
Lipase U/L 23
ALT/GPT U/L 19
Lactate(B) mg/dL 163.4
Osmolality(B) mosm/KgH2O 401
Methanol mg/dL <1.3
Alcohol mg/dL 298
Amphetamine(
U)
Absent
KETAMINE Negative
MDMA Negative
• Lactate acidosis
• Anion gap
• Delta-delta
• Osmo gap
Anion gap
• 139-4.4-85 = 49.6
• (49.6 – 10) / 19.6
Delta-delta
Osmo gap
• Calculated osmolality = 2 x [Na mmol/L] + [glucose mg/dL] / 18 + [BUN
mg/dL] / 2.8 + [Ethanol mg/dL / 3.7]
• 2 x 139 + 11.1 + 8.7 + 80.5 = 378.3
• 401 – 378 = 23
鏡檢組(U)
Color Yellow
Turbidity Cloudy
SP.Gravity 1.013
pH 5
Leukocyte Negative
Nitrite mg/dL Negative
Protein mg/dL 2+ (100)
Glucose mg/dL Negative
Ketone mg/dL 1+ (15)
Urobilinogen EU/dL 1
Bilirubin mg/dL Negative
Blood 2+
RBC /uL 33
WBC /uL 0
Squamus Epi /uL 15
Hyaline cast /uL 1
Granular cast /uL 1
Bacteria Positive
Conclusion
• Metabolic acidosis with mixed with alkalosis
檢驗項目 單位 1081114
血液組(CBC)
WBC 1000/uL 3.2
RBC million/uL 3.73
Hemoglobin g/dL 12
Hematocrit % 34.9
MCV fL 93.6
MCH pg/Cell 32.2
MCHC g/dL 34.4
RDW % 13.3
Platelets 1000/uL 147
Segment % 87.1
Lymphocyte % 8.5
Monocyte % 4.4
Eosinophil % 0
Basophil % 0
Impression
1. Alcoholic ketoacidosis
2. Lactate acidosis, metformin related?
3. T2DM with poor controlled
Acidosis
Hypokalemia
• Weakness, rhabdo
• Abdominal hypokinesia
hyperkalemia
treatment

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Momi

  • 1. General Data • 病歷號碼:21717159 • 年齡:48 • 性別:男 • 職業:無 • 種族:臺灣 • 婚姻:已婚
  • 2. Chief Complaint • General weakness for one week – DDX – AEIOU TIPs
  • 3. Underlying disease • Hx of pancreatitis • T2DM
  • 4. Underlying disease • Pancreatitis at 2015/05 complicated with ARDS, necrotizing pancreatitis, abdominal compartment syndrome – s/p necrosectomy + drainage • T2DM, diagnosed 2015/07, by OHA / Insulin, but poor compliance – 2017 ~ 2019/08 : no medication record – 2017/10/12 HbA1C=10.9%
  • 5. Present illness Abdominal pain Poor appetite, nausea, thirsty sensation Dyspnea, progressed for 2 weeks Decreased urine amount There was no fever, no chillness, no chest pain, no productive cough, nor limbs edema
  • 6. Personal History • Person Hx : Alcoholism • Alcohol : 藥酒(Alc. 20~30%) 300cc/day for 10+ years Smoking : 1PPD for 10+ years Betelnut : 400$ for 10+ years
  • 7. Physical Examination • T:35.9 P:124 R:18 SBP:124 DBP:82 E:4 V:5 M:6 • Height : 164 cm BW: 51 kg BMI:19 • General appearance : ill, alochol smell • Conscious : clear Pupil size : 3+/3+ • HEENT not anemic, not icteric • throat- not injected • Neck no jugular enlargement • no lymphadenopathy • Chest: BS clear • Heart : RHB , no murmur • Abdomen soft and flat • no tenderness • no rebound pain • bowel sound : normoactive • Mcburney point : negative • Murphy sign : negative • Extremities: free movable, no edema
  • 8. lab Temperature ℃ 37 pH 7.097 pCO2 mmHg 14.6 pO2 mmHg 126.7 HCO3 mmol/L 4.4 TCO2 mmol/L 4.8 ABE mmol/L -23.1 SBE mmol/L -25.3 SBC mmol/L 8.5 SAT % 98 檢驗項目 單位 1081113 血液組(CBC) WBC 1000/uL 19.1 RBC million/uL 4.26 Hemoglobin g/dL 14 Hematocrit % 40.8 MCV fL 95.8 MCH pg/Cell 32.9 MCHC g/dL 34.3 RDW % 13.2 Platelets 1000/uL 327 Segment % 89.5 Lymphocyte % 4.8 Monocyte % 5 Eosinophil % 0.2 Basophil % 0.5 BUN (B) mg/dL 24.6 Creatinine(B) mg/dL 1.87 Na mEq/L 139 K mEq/L 5.1 Cl mEq/L 85 Lipase U/L 23 ALT/GPT U/L 19 Lactate(B) mg/dL 163.4 Osmolality(B) mosm/KgH2O 401 Methanol mg/dL <1.3 Alcohol mg/dL 298 Amphetamine( U) Absent KETAMINE Negative MDMA Negative
  • 9. • Lactate acidosis • Anion gap • Delta-delta • Osmo gap
  • 10. Anion gap • 139-4.4-85 = 49.6 • (49.6 – 10) / 19.6 Delta-delta
  • 11. Osmo gap • Calculated osmolality = 2 x [Na mmol/L] + [glucose mg/dL] / 18 + [BUN mg/dL] / 2.8 + [Ethanol mg/dL / 3.7] • 2 x 139 + 11.1 + 8.7 + 80.5 = 378.3 • 401 – 378 = 23
  • 12. 鏡檢組(U) Color Yellow Turbidity Cloudy SP.Gravity 1.013 pH 5 Leukocyte Negative Nitrite mg/dL Negative Protein mg/dL 2+ (100) Glucose mg/dL Negative Ketone mg/dL 1+ (15) Urobilinogen EU/dL 1 Bilirubin mg/dL Negative Blood 2+ RBC /uL 33 WBC /uL 0 Squamus Epi /uL 15 Hyaline cast /uL 1 Granular cast /uL 1 Bacteria Positive
  • 13. Conclusion • Metabolic acidosis with mixed with alkalosis
  • 14.
  • 15. 檢驗項目 單位 1081114 血液組(CBC) WBC 1000/uL 3.2 RBC million/uL 3.73 Hemoglobin g/dL 12 Hematocrit % 34.9 MCV fL 93.6 MCH pg/Cell 32.2 MCHC g/dL 34.4 RDW % 13.3 Platelets 1000/uL 147 Segment % 87.1 Lymphocyte % 8.5 Monocyte % 4.4 Eosinophil % 0 Basophil % 0
  • 16. Impression 1. Alcoholic ketoacidosis 2. Lactate acidosis, metformin related? 3. T2DM with poor controlled
  • 18. Hypokalemia • Weakness, rhabdo • Abdominal hypokinesia

Editor's Notes

  1. 19.6 x 1.2 25.4
  2. AG / HCO3 = AG酸根 / 失去的鹼 (間接代表非AG酸)