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The connection between genetics and kidney disease lies in the role of inherited genetic factors that can increase the risk of developing various kidney diseases. Certain kidney diseases, such as Polycystic Kidney Disease (PKD) and Alport Syndrome, have a clear genetic component where mutations in specific genes contribute to the development of these conditions. Understanding these genetic basis is vital for assessing the risk of kidney disease in individuals with family history and for advancing personalized medicine approaches in prevention, diagnosis and treatment. Genetic testing plays a significant role in identifying these predispositions and guiding healthcare strategies.

GENETICS and KIDNEY DISEASES /

AFFIFA HUSSAIN

Oppenheimer & Co. Inc, co-Head of Healthcare Investment Banking, Michael Margolis, provides H1 Healthcare Financing, Funding and M&A Overview. Table of Contents 1. Broader Market Overview 2. Biotech M&A Market Overview 3. Private Biotech Financing Market Update 4. Key Advice For Healthcare Companies Current State of Play; Healthcare has Underperformed the Broader Market Over the Last Twelve Months; Signal-to-Noise is Getting Worse; Healthcare IPO Activity has Decreased Significantly Since 20–21 Pandemic Levels; Biotech Financing Activity Has Remained Robust in 2024; Biotech M&A Market Remains Incredibly Active; Biotech M&A Market Remains Incredibly Active; Big Pharma Upcoming Patent Expirations; Since November 2023 Oncology has accounted for over half of all M&A; Oncology, Autoimmune / I&I, and CV & Metabolic Remain the Top Areas in M&A; Small Molecule Beats Out All Other Modalities in M&A Despite IRA Concerns; Value of Big Pharma Acquisitions by Therapeutic Area in Q1 2024; Private Financing Market Update; 2024 Private Placement Activity On Track to Approach, If Not Exceed, 2020 Levels; Oncology, Particularly Solid Tumor, Continues to Attract VC Investors; Despite the IRA, Small Molecules Continue to Attract VC Dollars; Preclinical-Stage Companies Make Up Almost Half of Private Placements in 2023; Valuations by Development Stage – 2023; Typical Biotech Investors Remained Active in Q1 2024; 23 $100M+ Deals were Raised in Q1 2024; Biotech Fundraising Momentum Continued into 2024; Key Advice For Israeli Healthcare Companies; Although Israel has Strong Presence on US Public Markets, There is Room to Grow; Telling Your Story Effectively; Interacting with Investors to Build Long-term Credibility; Seven Simple Rules for Pitch Decks;

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Healthcare Finance and M&A, What Comes Next? Presentation by Matthew R. Kittay, National Co-Chair, M&A Practice Group, Fox Rothschild LLP. Includes fundraising and investments. Breakouts by subsector- Healthcare (overall), Healthcare services, Digital health, Biopharma, Pharmatech, Medtech, Healthcare IT. Healthcare transaction distribution breakouts. Exits remain flat. Avoiding common legal pitfalls like IP, compliance, governance structure. Current legislation in health law. IP strategy for healthtech.

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WORLD HEALTH ORGANIZATION WE CHAMPION HEALTH AND A BETTER FUTURE FOR ALL’ INTRODUCTION- WHO leads and champions global efforts to give everyone, everywhere, an equal chance to live a healthy life. HISTORY- founded in 1948, 7 April HEADQUARTERS- Geneva OFFICES- 6 semi autonomus regional and 150 fields offices DIRECTOR- Dr. Tedros Adhanam Ghebeyesus OBJECTIVES- Direction, co-ordination agencies Collaboration with local bodies Help the government in health services Proper technological assistance To attain highest possible level of health Prioritize and support health Formulate health policies Disease inspection and analysis Health education GOAL: To ensure that a billion more people have universal health coverage, to protect a billion more people from health emergencies and provide a further billion people with better health and well being ORGANIZATION: executive board, secretariat, world health assembly FUNCTION: FOR UNIVERSAL HEALTH Focus on PHCare Sustainable financing and protection Access to health products and medicines Training of health workforce and advice on labor policies Support people participation in National health policies Increasing monitoring, data and information FOR HEALTH EMERGENCIES Identification, mitigation and risk management Prevention and support of development of tools Detect and respond to acute health emergencies Support delivery of essential health services FOR HEALTH AND WELL BEING Address social determinants Promote intersectoral approach for health Prioritize health in all policies and healthy settings THROUGH WORK, ADDRESS Prevention of non- communicable disease Mental health promotion Climate change Antimicrobial resistance Elimination and eradication of communicable disease UNITED NATION FUND FOR POPULATION ACTIVITYINTRODUCTION- SEXUAL AND REPRODUCTIVE HEALTH AGENCY MISSION- To deliver a world where every pregnancy is wanted, every childbirth is safe, and every young person’s potential is fullfilled AIM- to improve reproductive and maternal health worldwide ESTABLISHED YEAR- 1969 (1974 in INDIA) HEADQUARTER- NEW YORK DIRECTOR- Dr. Natalia Kanem (2017) FUNCTION Develop national healthcare Increasing the access to birthcontrol Leading campaigns against child marriage Prevention of violence against gender Prevention of female genital mutiliation Treatment and prevention of STD and RTI MCH care HIV prevention and treatment IEC on sexuality and treatment of infertility and Abortion FOCUS area: Reproductive health Gender equality Population and development strategies Girl education Political participation for women FGM Child marriage UNITED NATION DEVELOPMENT PROGRAMME 1965 ESTABLISHED- 22 November. 1965 HEADQUARTER- New York HEAD- Achim steiner STRUCTURE- 170 member countries and territories INTRODUCTION- Advocates for change and connect countries to knowledge, experience and resources to help people bulid a better life for themselves Encourages Human right protection, women empowerment in all its programme

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A well-known hospital in Gwalior, Madhya Pradesh, ITM Hospital & Research Center has recently updated its super specialty and elevated the pre-existing facilities including critical care and minimal invasive surgery protocols. As per the hospital's management team, "The 300-bedded tertiary care hospital operates under the guidance of highly experienced medical and healthcare professionals and includes 20 ICU beds, 20 beds for Obs, Gynae, and NICU, three modern operating theaters, a well- equipped and 24x7 available ER department, dialysis center, a dedicated mother and child care unit, along with highly advanced technologies like CT scan, MRI, Bone DEXA along with ECHO, TMT, Physiotherapy and more. Our highly experienced doctors bring a multidisciplinary approach across 25+ super specialties, including oncology, cardiology, joint replacement, minimal access surgery and others. We aim to enhance health care in Gwalior, Madhya Pradesh by providing quality medical care with trust, transparency and empathy while meeting all safety standards," says Mr. Ramashankar Singh, Chairman of the hospital. The hospital has also been recognised as the best emerging hospital in the vicinity for several specialties for following the moral of “Sewa Samta aur Sammaan”. Dr. Ramashankar adds, "This recognition is a testament to our mission of serving people with the best critical care and minimal invasive surgery. We remain committed to delivering outcome-driven experiences and care to treat and heal people, based on the same values that the group has followed for the past three decades”

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Etiology for RRT and Code Blue Workshop.

GENETICS and KIDNEY DISEASES /

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mHealth Israel_Healthcare Finance and M&A- What Comes Next

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ITM HOSPITAL The hospital has also been recognised as the best emerging hosp...

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Making change happen: learning from "positive deviancts"

Tortora PRINCIPLES OF ANATOMY AND PHYSIOLOGY - Tortora - 14th Ed.pdf

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