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Hyiodine 2012 presentation for clinicians and nurses
1.
2. Why hyaluronic acid for wound
healing?
HA is responsible for
scarless healing in fetus
„Healing by regeneration“
3. What is hyaluronic acid (HA) ?
• Natural part of human body (tissue, eyes , joints)
Part of extracellular matrix
• Important for Migration, Differentiation and
Proliferation of cells (fibroblasts, keratinocytes)
• Has high affinity for water, creates moist environment
HA HAS UNIQUE REGENERATIVE PROPERTIES
5. HYIODINE based on SYNERGY
Unique wound healing
and regeneration properties ACTIVELY STIMULATES THE
of HYALURONIC ACID HEALING PROCESS
& SUITABLE FOR HEALING
CHRONIC AND INFECTED
Antimicrobial properties WOUNDS
of IODINE
7. INDICATIONS
1) CHRONIC, STAGNATING WOUNDS MAKING NO PROGRESS
• Diabetic ulcers
• Deep wounds, fistulae, sinuses
• Infected, dehisced wounds after surgery
• Leg ulcers (venous, arterial)
• Pressure ulcers
2) ACUTE, TRAUMATIC WOUNDS
8. APPLICATION METHODS
• Via carrier dressing • Directly to the wound
for all kinds of wounds for small wounds, fistulae,
sinuses
very effective and versatile
application can be injected in wounds
9. COMBINATION WITH OTHER DRESSINGS
• Parafin (oily) gauze • Alginate
Dry wounds. Infected, sloughy wounds.
• PU foam • Inadine
Clean, non-infected infected wounds
wounds only ! To reduce requency of
dressings.
10. DRESSING CHANGES
• After first application • In infected wounds
next change within 24 hrs DAILY dressings needed
• In non-infected, clean wounds • MRSA infected wounds
dressings every 2-3 days antibiotics NOT needed
11. HYIODINE SAFETY
In clinical use for over 5 years
No adverse effects or alergic
reactions reported
May be used for indefinite period
of time due to the very low
content of iodine
12. STIMULATES GRANULATION GROWTH
WK 0 WK 12
56 year old male, non healing wound after amputation of the forefoot
Indicated therapy by negative pressure, which failed
13. PREVENTS LEG AMPUTATION
WK 1 WK 5 WK 12
48 year old female, deep, heavily infected diabetic ulcer, 30% blood vessel blocked,
affected tendons, leg amputation recomended
14. STIMULATES THE HEALING PROCESS
WK 1 WK 2 WK 23
Deep infected wound after aorto-coronary bypass in obese diabetic patient.
Editor's Notes
A: limited use of HA due to its sensitivity to bacteria enzymes, HA can be easily degradated high price of HA as a raw material for production (Contipro is HA manufacturer what eliminates this disadvantage)
The first group of indication is the best target for Hyiodine, in red colour the best target from marketing point of view The second group of indications is also good, but with lower rate of efficacy,