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2. Introduction
• Pharmaceutical intermediates are
chemical compounds which form the
building blocks of the active
pharmaceutical ingredient (API).
• Pharmaceutical intermediates are
produced as a by-product during the
production of API.
• Every reaction in the production process
of API gives rise to various different
pharmaceutical intermediates.
• Pharmaceutical intermediates are used in
the production of bulk drugs and also for
research and development purpose by
various pharma and biopharma
companies.
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3. Examples of drug value chains
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6. Bulk drug intermediates
Bulk drug intermediates are
the drugs used as raw
materials for the production of
bulk drugs, or they can refer to
a material produced during
synthesis of an API that must
undergo further molecular
change or processing before it
becomes an API.
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7. Market Scenario
Profit by Knowledge
The global
pharmaceutical
intermediates market is
expected to reach US$
37,290. 33 million in
2028 from US$ 27,356.
70 million in 2020. The
market is estimated to
grow with a CAGR of 3.
95% during 2020-2028.
8. The market of drug intermediates
is segmented on the basis of type
of intermediate, end user, and by
region. On the basis of type of
intermediate, the market is
segmented into two main types,
API intermediate, and advanced
intermediate.
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Market Segmentation
11. The way to go
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India’s API industry was ahead of China in the 1990s, but thanks to the latter
providing various benefits such as free land, cheap utilities such as water and
power, and negligible financing costs, China took the lead and soon became the
global leader in APIs, thereby making Indian pharmaceutical companies dependent
on Chinese API manufacturers for raw materials. In order to make India the new
global API hub, the API and intermediate parks will have to be set up where
companies get benefits when it comes to utilities and financing. Many companies in
the chemical sector are unwilling to enter this space due to the large number of
regulations in the pharmaceutical sector and lack of knowledge. The government
will have to ease regulations and make it easy for companies to set up an API or
intermediate manufacturing plant.