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Presentation Suggestions
    Dr. Burnett and Dr. Singiser
         BIOL/CHEM 4900




                    Photo courtesy of Dr. Nickie Cauthen
A Sad Day on
Sesame Street

• Citing your images
• Use small print




                       http://www.bilibala.com/veryveryfunny/html/jokedata/sadday.html
Example of a Bad Color Scheme
• Fonts in the same color family as the
  background do not show up well.
• Here are some tips for good color
  combinations
  – Use the Design Templates
     • Go under the format menu and select Slide Design
  – Use the Standard Color schemes
     • You can’t go wrong with the dark blue background
       and yellow or white text
Another Bad Color Scheme
• Dark text on dark background
• Beware of shaded backgrounds




• The dark text is harder to read down here
Distracting Backgrounds
• Color
  – Too bright
  – Not enough contrast
  – Some colors will look different when projected
• Distracting designs
Regulation of Herbs and Drugs
• Regulation varies from country to country
• Herbs are classified as dietary supplements in
  United States
  – Manufacturers are limited in claims they can make
• US Regulating Agencies
  – American Herbal Products Association
  – Natural Nutritional Foods Association
• Safety with herbs
  – Be informed
  – Dosage
  – Side effects
Text on Slides
• How much text should be on a slide?
• Presentation vs. lecture
• Bullet points
Decorating Your House
              for Halloween
•   It is important to decorate your house for Halloween so that children
    can find who is giving out candy. If your house isn’t decorated then
    kids won’t come to your house.
•   Spooky decorations are fun, but they may scare the smaller kids away.
•   Cheesy decorations can be found EVERYWHERE and most people
    love them.
•   Funny decorations can be offensive to some so be careful. Make sure
    they are politically correct and clean.
•   Homemade decorations are the cheapest and they are fun to make.
    You can make spooky, cheesy and funny decorations for ½ the cost of
    buying them.
Halloween Decorations
• Importance
   – Spirit
   – Marking your house
• Types of Decorations
   – Spooky
      • Frightening
      • Hard to find
   – Cheesy
      • Cheap
      • Easy to find
      • Loved by all
   – Funny
      • Can be offensive   Photo courtesy of Dr. Nickie Cauthen

   – Homemade
      • Cheap
      • Fun to make
      • Variety
Plasmodium Life Cycle




     http://www.who.int/tdr/diseases/malaria/lifecycle.htm
Plasmodium Life Cycle
•   Mosquito bite
•   Sporozoites enter blood
•   Travel to liver
     – Hepatocytes
     – Asexual growth
         • Schizonts  merozoites
     – Merozoites to blood
•   Merozoa to blood
     – Infect RBC
         • Release trophozoites,
           merozoites, schizonts
     – Merozoite transformation
                                    http://www.who.int/tdr/diseases/malaria/lifecycle.htm
         • Gametocytes
•   Passed to new mosquito
     – Sexual cycle
Summary of Helpful Points
•   Fewer words on slides
•   A picture says a thousand words
•   Don’t read the slides
•   Use correct grammar and spelling
•   Animation
    – Often helpful, but not always necessary
• Explain your graphics
• Keep slides in order; don’t flip back and forth
    – Repeat slides if necessary
•   Point things out using laser pointer, stick, whatever
•   Make eye contact (with everyone)
•   Don’t turn your back on the audience
•   Avoid hugging the podium
Summary of Helpful Points
• Speak in a clear, loud voice
   – Don’t trail off
• Slow down and think about what you are saying
• Practice your presentation
   –   Helps to avoid “um”, “okay”, etc.
   –   Helps pacing for time allotted
   –   Helps with pronunciation
   –   Don’t memorize (sounds scripted)
• Engage your audience
• When asking a question, if asked repeat it IN A DIFFERENT
  WAY (they obviously didn’t get it the first time)
• Answer any questions and if you don’t know, you don’t know!!!
• If you don’t understand a question ask for a repeat
What is wrong with the
  following slides?
THE CENTRAL DOGMA OF
     MOLECULAR BIOLOGY
Transcription of DNA to RNA to protein:
1.The DNA replicates its information in a process
 that involves many enzymes: replication.
2. The DNA codes for the production of messenger
     RNA (mRNA) during transcription.
3. In eucaryotic cells, the mRNA is processed and
     migrates from the nucleus to the cytoplasm.
4. Messenger RNA carries coded information to
     ribosomes. The ribosomes "read" this
     information and use it for protein synthesis. This
     process is called translation.
• Located
  approximately 25-30
  bases pairs upstream
  of the transcriptional
  unti the TATA box is
  highly conserved
  sequence that works
  to help position RNA
  plms during initiation
  of transcription.
More Practice

What is the enthalpy change during the process in which
100.0 g of water at 50.0 °C is cooled to ice at –30.0 °C
under a constant pressure of 1 atm? The specific heats of
ice, water, and steam are 2.03 J/g-K, 4.18 J/g-K, and 1.84
J/g-K, respectively. For H2O, ΔHfus = 6.01 kJ/mol and ΔHvap
= 40.67 kJ/mol.?




                                                       © 2009, Prentice-
                                                           Hall, Inc.
SOM Output
RNA information (in the form of
nucleotide sequences) is then
TRANSLATED into proteins
(long polypeptide chains) by
complex units called ribosomes.

Proteins are the work horses of
biological systems, i.e. enzymes,
messengers, and building blocks.
URSIDAE (Bears)
   Large Size: Bears are large-bodied compared to many other carnivores.
    Most of their diet consists of vegetable matter. Meat is digested quickly but
    vegetable matter takes much longer. Larger body size brings a decrease in
    metabolic rate, so large body animals can survive on the small energy from
    vegetable matter, even though they have to eat a vast amount of food to
    satisfy their total energy needs.
   Powerful limbs and strong claws: Bears have long, powerful limbs with
    strong claws used in climbing trees, digging and grubbing. The scapula has
    a post-scapular fossa for the attachment of the subscapularis minor muscle
    which prevents the humeri popping out of their joints as a bear hauls its
    large body weight up trees.
   Grinding Molars: The premolars of bears are much smaller than other
    carnivores and often lost at old age. The molars are broadened and
    flattened for crushing and grinding up tough vegetable matter.
   Long Muzzle: The long, powerful muzzle with its mobile snout and
    protruding lips are important for digging and grubbing. The long muzzle is
    also a place for olfactory epithelium which accounts for the excellent sense
    of smell.
   Vestigial Tail: Unlike many other carnivores bears have a tail with no
    specialized function.
 Example of bad animations
  Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
 Example of bad animations
  Example of bad animations
 Example of bad animations
BLUNT END VS. STICKY END
 HaeIII and AluI cut straight across the
  double helix producing "blunt" ends.
  However, many restriction enzymes cut in
  an offset fashion.
 The ends of the cut have an overhanging
  piece of single-stranded DNA. These are
  called "sticky ends" because they are able
  to form with any base pair DNA molecule
  that contains the complementary sticky end.
  Any other source of DNA treated with the
Miotics
                                                                          Side effects:
-Pilocarpine                                                          1.   pain inside the eye first few days
a choline ester miotic and a positively charged quaternary ammonium
          compound.Increase secretion by the exocrine glands.
                                                                      2.   Blurred vision
         increase secretion by the exocrine glands, and               3.   extreme nearsightedness (younger age)
         produces contraction of the iris sphincter muscle            4.   reduce pupil size and prevent normal dilation,
         and ciliary muscle by mainly stimulating muscarinic
         receptors.                                                        dim vision, especially at night or in dark
        3times a day                                                      rooms
-Carbachol                                                            5.   Stuffy nose, sweating, increased salivation
-produces constriction of the iris and ciliary body                   6.   occasional gastrointestinal (stronger miotics)
      resulting in reduction in intraocular pressure


-Echothiophate
         long-acting cholinesterase inhibitor which
         enhances the effect acetylcholine in iris,
         ciliary muscle.It causes miosis, increase in
         facility of outflow of aqueous humor, and fall
         in intraocular pressure
QuickTime™ and a
TIFF (Uncompressed) decompressor
   are needed to see this picture.
Energy Changes Associated with
       Changes of State
               The heat added to the
                system at the melting
                and boiling points goes
                into pulling the
                molecules farther apart
                from each other.
               The temperature of the
                substance does not rise
                during a phase change.

                                 © 2009, Prentice-
                                     Hall, Inc.
Outgroup Monotremata
  Didelphimorphia

  Paucituberculata

  Microbiotheria

  Dasyuromorphia

  Peramelemorphia

  Notorcytemorphia



Diprotodontia
The strands are held in position, binding
     easily to DNA polymerase, which
     catalyzes the elongation of the leading
     and lagging strands.
     While the DNA polymerase on the
     leading strand can operate in a
     continuous fashion, RNA primer is
     needed repeatedly on the lagging strand
     to facilitate synthesis of Okazaki
     fragments.
Hydrophobic and
Hydrophilic
• Hydrophilic-- water loving or a
  molecule that is capable of
  forming a hydrogen bond with
  water.
• Hydrophobic-- water hating or a
  molecule that repels water.
• Important function in cell’s
  membrane structure.
Hydrophobic versus
                                      Hydrophilic




                                                                  http://www.uic.edu/classes/bios/bios100/lecturesf04am/lect02.htm




http://academic.brooklyn.cuny.edu/biology/bio4fv/page/hydro.gif
DFA – Results
How Do Neural Networks Compute?
 Activation = the final value of a particular
  unit.

 Calculated by adding inputs and bias

 Activation function
W1         Bias


W2          Σ                               Final
                                          Activation
W3        Net Input
                        Activation
                        Function

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PPT+check

  • 1. Presentation Suggestions Dr. Burnett and Dr. Singiser BIOL/CHEM 4900 Photo courtesy of Dr. Nickie Cauthen
  • 2. A Sad Day on Sesame Street • Citing your images • Use small print http://www.bilibala.com/veryveryfunny/html/jokedata/sadday.html
  • 3. Example of a Bad Color Scheme • Fonts in the same color family as the background do not show up well. • Here are some tips for good color combinations – Use the Design Templates • Go under the format menu and select Slide Design – Use the Standard Color schemes • You can’t go wrong with the dark blue background and yellow or white text
  • 4. Another Bad Color Scheme • Dark text on dark background • Beware of shaded backgrounds • The dark text is harder to read down here
  • 5. Distracting Backgrounds • Color – Too bright – Not enough contrast – Some colors will look different when projected • Distracting designs
  • 6. Regulation of Herbs and Drugs • Regulation varies from country to country • Herbs are classified as dietary supplements in United States – Manufacturers are limited in claims they can make • US Regulating Agencies – American Herbal Products Association – Natural Nutritional Foods Association • Safety with herbs – Be informed – Dosage – Side effects
  • 7. Text on Slides • How much text should be on a slide? • Presentation vs. lecture • Bullet points
  • 8. Decorating Your House for Halloween • It is important to decorate your house for Halloween so that children can find who is giving out candy. If your house isn’t decorated then kids won’t come to your house. • Spooky decorations are fun, but they may scare the smaller kids away. • Cheesy decorations can be found EVERYWHERE and most people love them. • Funny decorations can be offensive to some so be careful. Make sure they are politically correct and clean. • Homemade decorations are the cheapest and they are fun to make. You can make spooky, cheesy and funny decorations for ½ the cost of buying them.
  • 9. Halloween Decorations • Importance – Spirit – Marking your house • Types of Decorations – Spooky • Frightening • Hard to find – Cheesy • Cheap • Easy to find • Loved by all – Funny • Can be offensive Photo courtesy of Dr. Nickie Cauthen – Homemade • Cheap • Fun to make • Variety
  • 10. Plasmodium Life Cycle http://www.who.int/tdr/diseases/malaria/lifecycle.htm
  • 11. Plasmodium Life Cycle • Mosquito bite • Sporozoites enter blood • Travel to liver – Hepatocytes – Asexual growth • Schizonts  merozoites – Merozoites to blood • Merozoa to blood – Infect RBC • Release trophozoites, merozoites, schizonts – Merozoite transformation http://www.who.int/tdr/diseases/malaria/lifecycle.htm • Gametocytes • Passed to new mosquito – Sexual cycle
  • 12. Summary of Helpful Points • Fewer words on slides • A picture says a thousand words • Don’t read the slides • Use correct grammar and spelling • Animation – Often helpful, but not always necessary • Explain your graphics • Keep slides in order; don’t flip back and forth – Repeat slides if necessary • Point things out using laser pointer, stick, whatever • Make eye contact (with everyone) • Don’t turn your back on the audience • Avoid hugging the podium
  • 13. Summary of Helpful Points • Speak in a clear, loud voice – Don’t trail off • Slow down and think about what you are saying • Practice your presentation – Helps to avoid “um”, “okay”, etc. – Helps pacing for time allotted – Helps with pronunciation – Don’t memorize (sounds scripted) • Engage your audience • When asking a question, if asked repeat it IN A DIFFERENT WAY (they obviously didn’t get it the first time) • Answer any questions and if you don’t know, you don’t know!!! • If you don’t understand a question ask for a repeat
  • 14. What is wrong with the following slides?
  • 15. THE CENTRAL DOGMA OF MOLECULAR BIOLOGY Transcription of DNA to RNA to protein: 1.The DNA replicates its information in a process that involves many enzymes: replication. 2. The DNA codes for the production of messenger RNA (mRNA) during transcription. 3. In eucaryotic cells, the mRNA is processed and migrates from the nucleus to the cytoplasm. 4. Messenger RNA carries coded information to ribosomes. The ribosomes "read" this information and use it for protein synthesis. This process is called translation.
  • 16. • Located approximately 25-30 bases pairs upstream of the transcriptional unti the TATA box is highly conserved sequence that works to help position RNA plms during initiation of transcription.
  • 17. More Practice What is the enthalpy change during the process in which 100.0 g of water at 50.0 °C is cooled to ice at –30.0 °C under a constant pressure of 1 atm? The specific heats of ice, water, and steam are 2.03 J/g-K, 4.18 J/g-K, and 1.84 J/g-K, respectively. For H2O, ΔHfus = 6.01 kJ/mol and ΔHvap = 40.67 kJ/mol.? © 2009, Prentice- Hall, Inc.
  • 19. RNA information (in the form of nucleotide sequences) is then TRANSLATED into proteins (long polypeptide chains) by complex units called ribosomes. Proteins are the work horses of biological systems, i.e. enzymes, messengers, and building blocks.
  • 20. URSIDAE (Bears)  Large Size: Bears are large-bodied compared to many other carnivores. Most of their diet consists of vegetable matter. Meat is digested quickly but vegetable matter takes much longer. Larger body size brings a decrease in metabolic rate, so large body animals can survive on the small energy from vegetable matter, even though they have to eat a vast amount of food to satisfy their total energy needs.  Powerful limbs and strong claws: Bears have long, powerful limbs with strong claws used in climbing trees, digging and grubbing. The scapula has a post-scapular fossa for the attachment of the subscapularis minor muscle which prevents the humeri popping out of their joints as a bear hauls its large body weight up trees.  Grinding Molars: The premolars of bears are much smaller than other carnivores and often lost at old age. The molars are broadened and flattened for crushing and grinding up tough vegetable matter.  Long Muzzle: The long, powerful muzzle with its mobile snout and protruding lips are important for digging and grubbing. The long muzzle is also a place for olfactory epithelium which accounts for the excellent sense of smell.  Vestigial Tail: Unlike many other carnivores bears have a tail with no specialized function.
  • 21.  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations  Example of bad animations
  • 22. BLUNT END VS. STICKY END  HaeIII and AluI cut straight across the double helix producing "blunt" ends. However, many restriction enzymes cut in an offset fashion.  The ends of the cut have an overhanging piece of single-stranded DNA. These are called "sticky ends" because they are able to form with any base pair DNA molecule that contains the complementary sticky end. Any other source of DNA treated with the
  • 23. Miotics  Side effects: -Pilocarpine 1. pain inside the eye first few days a choline ester miotic and a positively charged quaternary ammonium compound.Increase secretion by the exocrine glands. 2. Blurred vision increase secretion by the exocrine glands, and 3. extreme nearsightedness (younger age) produces contraction of the iris sphincter muscle 4. reduce pupil size and prevent normal dilation, and ciliary muscle by mainly stimulating muscarinic receptors. dim vision, especially at night or in dark  3times a day rooms -Carbachol 5. Stuffy nose, sweating, increased salivation -produces constriction of the iris and ciliary body 6. occasional gastrointestinal (stronger miotics) resulting in reduction in intraocular pressure -Echothiophate long-acting cholinesterase inhibitor which enhances the effect acetylcholine in iris, ciliary muscle.It causes miosis, increase in facility of outflow of aqueous humor, and fall in intraocular pressure
  • 24. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 25. Energy Changes Associated with Changes of State  The heat added to the system at the melting and boiling points goes into pulling the molecules farther apart from each other.  The temperature of the substance does not rise during a phase change. © 2009, Prentice- Hall, Inc.
  • 26. Outgroup Monotremata Didelphimorphia Paucituberculata Microbiotheria Dasyuromorphia Peramelemorphia Notorcytemorphia Diprotodontia
  • 27. The strands are held in position, binding easily to DNA polymerase, which catalyzes the elongation of the leading and lagging strands. While the DNA polymerase on the leading strand can operate in a continuous fashion, RNA primer is needed repeatedly on the lagging strand to facilitate synthesis of Okazaki fragments.
  • 28. Hydrophobic and Hydrophilic • Hydrophilic-- water loving or a molecule that is capable of forming a hydrogen bond with water. • Hydrophobic-- water hating or a molecule that repels water. • Important function in cell’s membrane structure.
  • 29. Hydrophobic versus Hydrophilic http://www.uic.edu/classes/bios/bios100/lecturesf04am/lect02.htm http://academic.brooklyn.cuny.edu/biology/bio4fv/page/hydro.gif
  • 31. How Do Neural Networks Compute?  Activation = the final value of a particular unit.  Calculated by adding inputs and bias  Activation function W1 Bias W2 Σ Final Activation W3 Net Input Activation Function