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• A 28 year-old man with no history of smoking, presented to the
emergency department with symptoms of cough, which was initially
dry with increased intensity for the past 6 months and progressive
breathlessness for 8 months, which had increased for 1 week and
diffuse chest pain, which was more on the left side.
Case
• There was no history of fever, hemoptysis, joint pain or skin rashes.
He had received anti-tuberculosis treatment 1 year ago for 6 months,
which was started based on radiological findings.
• He had worked in a stone crushing factory 2 years ago for 1 year; 7–
8 h/day.
• Pre- placement examination was not done at the time of
employement.
• On clinical examination, the patient was malnourished, with Modified
Medical Research Council (MMRC) dyspnea scale of 4, oxygen
saturation of 82%. On examination of the chest, there was hyper-
resonant note on percussion with very faint breath sounds in both
lung fields with scattered fine crackles.
• The patient was admitted with provisional diagnosis of acute silicosis
with bilateral pneumothorax as evidenced by clinical examinations
and chest X-ray
• What the are investigations need to done?
Investigations
• Complete blood count, renal function and liver function tests showed
no abnormality. Sputum for acid-fast bacilli (AFB) was negative.
• Chest X-ray showed snow-storm appearance with bilateral
pneumothorax and bilateral nodular type r/q opacities and profusions
of 3+ in both lung fields, consistent with the diagnosis of acute
silicosis as per revised edition of International Labour Office (ILO)
classification, 2011
• The patient was also subjected to bronchoscopy and collected
bronchoalveolar lavage (BAL) revealed macrophage laden silicotic
particles, therefore the patient was diagnosed as a case of acute
silicosis based on history, clinical and radiographic findings and
confirmed by laboratory reports of BAL findings.
• Enumerate the Differential Diagnosis
Differential Diagnosis
• The differential diagnosis includes
Pulmonary tuberculosis,
Pneumoconiosis,
Ssarcoidosis and other occupational diseases.
• The absence of AFB in the sputum, characteristic chest X-ray and the
presence of macrophage laden silicotic particle in BAL favour the
diagnosis of acute silicosis.
• How would you Manage this case?
Management
• No effective treatment
• Fibrotic changes that have already taken place, cannot be reversed.
• Rigorous dust control measures
• Regular physical examination of workers
For the case being discussed, bilateral intercostal chest tube to be
inserted under water seal drainage
Follow-up after 1 week and after 1 month of discharge
• List the various measures for the prevention of occupational diseases.
1- Medical Measures
• Pre-Placement Examination
• Periodical Examination
• Medical and Health Care Services
• Notification
• Supervision of working environment
• Health Education and Counselling
2- Engineering Measures
• Design of the building
• Good House-Keeping
• General Ventilation
• Mechanisation
• Substitution
• Dusts & Enclosure
• Isolation
- Local exhaust ventilation
- Protective devices
- Environmental monitoring
- Statistical monitoring
- Research
3. Legislation
- The Factories Act, 1948
- The Employees State Insurance Act, 1948
Thank You

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silicosis.pptx

  • 1. • A 28 year-old man with no history of smoking, presented to the emergency department with symptoms of cough, which was initially dry with increased intensity for the past 6 months and progressive breathlessness for 8 months, which had increased for 1 week and diffuse chest pain, which was more on the left side. Case
  • 2. • There was no history of fever, hemoptysis, joint pain or skin rashes. He had received anti-tuberculosis treatment 1 year ago for 6 months, which was started based on radiological findings. • He had worked in a stone crushing factory 2 years ago for 1 year; 7– 8 h/day. • Pre- placement examination was not done at the time of employement.
  • 3. • On clinical examination, the patient was malnourished, with Modified Medical Research Council (MMRC) dyspnea scale of 4, oxygen saturation of 82%. On examination of the chest, there was hyper- resonant note on percussion with very faint breath sounds in both lung fields with scattered fine crackles.
  • 4. • The patient was admitted with provisional diagnosis of acute silicosis with bilateral pneumothorax as evidenced by clinical examinations and chest X-ray
  • 5.
  • 6. • What the are investigations need to done?
  • 7. Investigations • Complete blood count, renal function and liver function tests showed no abnormality. Sputum for acid-fast bacilli (AFB) was negative. • Chest X-ray showed snow-storm appearance with bilateral pneumothorax and bilateral nodular type r/q opacities and profusions of 3+ in both lung fields, consistent with the diagnosis of acute silicosis as per revised edition of International Labour Office (ILO) classification, 2011
  • 8. • The patient was also subjected to bronchoscopy and collected bronchoalveolar lavage (BAL) revealed macrophage laden silicotic particles, therefore the patient was diagnosed as a case of acute silicosis based on history, clinical and radiographic findings and confirmed by laboratory reports of BAL findings.
  • 9. • Enumerate the Differential Diagnosis
  • 10. Differential Diagnosis • The differential diagnosis includes Pulmonary tuberculosis, Pneumoconiosis, Ssarcoidosis and other occupational diseases. • The absence of AFB in the sputum, characteristic chest X-ray and the presence of macrophage laden silicotic particle in BAL favour the diagnosis of acute silicosis.
  • 11. • How would you Manage this case?
  • 12. Management • No effective treatment • Fibrotic changes that have already taken place, cannot be reversed. • Rigorous dust control measures • Regular physical examination of workers For the case being discussed, bilateral intercostal chest tube to be inserted under water seal drainage
  • 13. Follow-up after 1 week and after 1 month of discharge
  • 14. • List the various measures for the prevention of occupational diseases.
  • 15. 1- Medical Measures • Pre-Placement Examination • Periodical Examination • Medical and Health Care Services • Notification • Supervision of working environment • Health Education and Counselling
  • 16. 2- Engineering Measures • Design of the building • Good House-Keeping • General Ventilation • Mechanisation • Substitution • Dusts & Enclosure • Isolation
  • 17. - Local exhaust ventilation - Protective devices - Environmental monitoring - Statistical monitoring - Research
  • 18. 3. Legislation - The Factories Act, 1948 - The Employees State Insurance Act, 1948