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SLEEP LESS, DIE EARLY
5 REASONS WHY SLEEP LOSS CAN SHORTEN YOUR LIFE

SONIA WIBISONO
Not getting enough sleep each night
can lead to serious health risks.
It can also have long lasting,
possibly permanent,

negative impact on your body and mind.
5 REASONS WHY SLEEP LOSS
CAN SHORTEN YOUR LIFE
COMPILED FROM DIFFERENT SOURCES,
ALL BASED ON SCIENTIFIC RESEARCHES
REASON #1

SLEEP LOSS DECREASES
IMMUNITY
#1: DECREASES IMMUNITY
People who are sleep
deprived have poor
antibody response to
flu vaccineโ€”less than
50%โ€”compared to
people with enough

sleep.
Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
#1: DECREASES IMMUNITY
People who are sleep
deprived have 73%
lower natural killer cells
activity, which plays a
major role in fighting
tumors, cancer, and

virus infected cells.

A natural killer cell

Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
#1: DECREASES IMMUNITY

A small natural killer cell is attacking a large cancer cell (left) and a tumor cell (right)
http://www.conkwest.com/natural-killer-cells
REASON #2

SLEEP LOSS INCREASES
RISK OF DIABETES
#2: INCREASES RISK OF DIABETES
Sleep loss can make
your body become
more insulin-resistant.
What that means is
normal levels of
insulin do not trigger
glucose absorption.

Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
#2: INCREASES RISK OF DIABETES
As a result, pancreas releases even more
insulin, which will result in a drop in blood sugar.

Insulin-resistance can progress to type-II
diabetes, which can reduce your life expectancy by
up to 10 years.

Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
REASON #3

SLEEP LOSS INCREASES
RISK OF OBESITY
#3: INCREASES RISK OF OBESITY
Lack of sleep can cause an imbalance between the
two hormones of hunger. Sleep loss results in lower
leptin (โ€œdo not eatโ€ hormone) and higher ghrelin
(โ€œeatโ€ hormone).

Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
#3: INCREASES RISK OF OBESITY
Consequently, you will feel
hungry all the time and
usually crave foods high in
carbs in particular.

Even after eating, you might
still feel unsatisfied. This can
ultimately lead to obesity.
Note: obese people live 3-12 years
less than normal-weight people.
Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
REASON #4

SLEEP LOSS INCREASES
RISK OF STROKE
#4: INCREASES RISK OF STROKE
Studies show that if you
get less than six hours of

sleep per night, you
have a 48% greater
chance of
developing/dying from
heart disease and 15%
greater chance of
developing/dying from
stroke.
http://www.theguardian.com/lifeandstyle/2011/feb/09/sleep-medical-research
#4: INCREASES RISK OF STROKE

Poor sleep increases the production of stress

hormones and drives up blood pressure, a major risk
factor for heart attacks and strokes.
http://en.wikipedia.org/wiki/Sleep_deprivation
REASON #5

SLEEP LOSS INCREASES
PROBABILITY OF ACCIDENTS
#5: INCREASES
PROBABILITY OF ACCIDENTS
Sleep deprivation was cited as a significant factor in
these catastrophes:
โ€ข Three Mile Islandโ€™s partial nuclear meltdown in
March 1979
โ€ข Nuclear meltdown at Chernobyl in April 1986
โ€ข Exxon Valdez oil spill in March 1989

http://healthysleep.med.harvard.edu/healthy/matters/consequences/sleep-performance-and-public-safety
#5: INCREASES
PROBABILITY OF ACCIDENTS
The National Highway Traffic
Safety Administration
conservatively estimates that
100,000 police-reported

crashes are the direct result of
driver fatigue each year.
It takes only 4 seconds of
attention lapse to result in a
potentially fatal crash.
http://drowsydriving.org/about/facts-and-stats/
Walker, M. P. Sleep Deprivation III: Brain Consequences [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
Now that you understand
how less sleep can cause early death,
you might want to consider
shutting down your computer
and get some sleep.
Disclaimer: The author cannot be held responsible for problems
caused by your getting caught sleeping during working hours.

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Sleep Less, Die Early

  • 1. SLEEP LESS, DIE EARLY 5 REASONS WHY SLEEP LOSS CAN SHORTEN YOUR LIFE SONIA WIBISONO
  • 2. Not getting enough sleep each night can lead to serious health risks. It can also have long lasting, possibly permanent, negative impact on your body and mind.
  • 3. 5 REASONS WHY SLEEP LOSS CAN SHORTEN YOUR LIFE COMPILED FROM DIFFERENT SOURCES, ALL BASED ON SCIENTIFIC RESEARCHES
  • 4. REASON #1 SLEEP LOSS DECREASES IMMUNITY
  • 5. #1: DECREASES IMMUNITY People who are sleep deprived have poor antibody response to flu vaccineโ€”less than 50%โ€”compared to people with enough sleep. Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 6. #1: DECREASES IMMUNITY People who are sleep deprived have 73% lower natural killer cells activity, which plays a major role in fighting tumors, cancer, and virus infected cells. A natural killer cell Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 7. #1: DECREASES IMMUNITY A small natural killer cell is attacking a large cancer cell (left) and a tumor cell (right) http://www.conkwest.com/natural-killer-cells
  • 8. REASON #2 SLEEP LOSS INCREASES RISK OF DIABETES
  • 9. #2: INCREASES RISK OF DIABETES Sleep loss can make your body become more insulin-resistant. What that means is normal levels of insulin do not trigger glucose absorption. Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 10. #2: INCREASES RISK OF DIABETES As a result, pancreas releases even more insulin, which will result in a drop in blood sugar. Insulin-resistance can progress to type-II diabetes, which can reduce your life expectancy by up to 10 years. Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 11. REASON #3 SLEEP LOSS INCREASES RISK OF OBESITY
  • 12. #3: INCREASES RISK OF OBESITY Lack of sleep can cause an imbalance between the two hormones of hunger. Sleep loss results in lower leptin (โ€œdo not eatโ€ hormone) and higher ghrelin (โ€œeatโ€ hormone). Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 13. #3: INCREASES RISK OF OBESITY Consequently, you will feel hungry all the time and usually crave foods high in carbs in particular. Even after eating, you might still feel unsatisfied. This can ultimately lead to obesity. Note: obese people live 3-12 years less than normal-weight people. Walker, M. P. Sleep Deprivation I: Immune Function & Metabolism [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 14. REASON #4 SLEEP LOSS INCREASES RISK OF STROKE
  • 15. #4: INCREASES RISK OF STROKE Studies show that if you get less than six hours of sleep per night, you have a 48% greater chance of developing/dying from heart disease and 15% greater chance of developing/dying from stroke. http://www.theguardian.com/lifeandstyle/2011/feb/09/sleep-medical-research
  • 16. #4: INCREASES RISK OF STROKE Poor sleep increases the production of stress hormones and drives up blood pressure, a major risk factor for heart attacks and strokes. http://en.wikipedia.org/wiki/Sleep_deprivation
  • 17. REASON #5 SLEEP LOSS INCREASES PROBABILITY OF ACCIDENTS
  • 18. #5: INCREASES PROBABILITY OF ACCIDENTS Sleep deprivation was cited as a significant factor in these catastrophes: โ€ข Three Mile Islandโ€™s partial nuclear meltdown in March 1979 โ€ข Nuclear meltdown at Chernobyl in April 1986 โ€ข Exxon Valdez oil spill in March 1989 http://healthysleep.med.harvard.edu/healthy/matters/consequences/sleep-performance-and-public-safety
  • 19. #5: INCREASES PROBABILITY OF ACCIDENTS The National Highway Traffic Safety Administration conservatively estimates that 100,000 police-reported crashes are the direct result of driver fatigue each year. It takes only 4 seconds of attention lapse to result in a potentially fatal crash. http://drowsydriving.org/about/facts-and-stats/ Walker, M. P. Sleep Deprivation III: Brain Consequences [PowerPoint slides]. Retrieved from http://bspace.berkeley.edu
  • 20. Now that you understand how less sleep can cause early death, you might want to consider shutting down your computer and get some sleep. Disclaimer: The author cannot be held responsible for problems caused by your getting caught sleeping during working hours.