The document discusses how DNA sequences can be converted into musical notes by representing the nucleotides as numerical values and encoding them in MIDI format. Specifically, it assigns numeric values to the nucleotides G, A, T, and C and represents the DNA string as a series of numbers. This numerical representation can then be played as musical notes by mapping the numbers to MIDI channels, octaves, and note values. By doing this abstraction and encoding, DNA sequences can be converted into music compositions.

1. Music from DNA strings Animesh Sharma

2. DNA strings? Word (sequence) Made out of 4 letters (nucleotides) Certain patterns more prevalent Hold information Coding Non Coding ...AGGGTTAGGGTTAGGGTTAGG...* ...AGGGTTAGGGTTAGGGTTAGG... ...AGGG TTAGGG TTAGGGTTAGG... * A Highly Conserved Repetitive DNA Sequence,(TTAGGG)n,Present at the Telomeres of Human Chromosomes Moyzis et al. PNAS | September 15, 1988 | vol. 85 | no. 18 | 6622-6626 Copyright © 1988 by the National Academy of Sciences ...UCCCAATCCCAAUCCCAAUCC...

3. Abstraction At nMers and repeat level ...AGGGTTAGGGTTAGGGTTAGG... AGG = 0 GTT = 1 ... 0 1 0 1 0 1 0 ... Frequency level ...AGGGTTAGGGTTAGGGTTAGG... G = 1 ...011100011100011100011... A = 1 ...100000100000100000100... T = 1 ...000011000011000011000... C = 1 ...000000000000000000000...

4. REF: Ab initio gene identification: prokaryote genome annotation with GeneScan and GLIMMER. Aggarwal G, Ramaswamy R. J Biosci. 2002 Feb;27(1 Suppl 1):7-14. G = 1 ...011100011100011100011... A = 1 ...100000100000100000100... T = 1 ...000011000011000011000... C = 1 ...000000000000000000000...

5. * MIDI-Perl , http://search.cpan.org/~sburke/MIDI-Perl-0.81/ OR http://interglacial.com/~sburke/midi-perl/ Sean M. Burke 30 Jan 2005. What about Music? Encode ^ MIDI::Perl * C – Channel O – Octave N – Note ^ The Musician's Guide to MIDI by Christian Braut

6. Thanks I hope I took less than 15 mts !