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13. Describe the 3 stages of cell signalling (using the examples of a) a growth factor, b) epinephrine and c) testosterone) a. Reception - role of receptors, when are the receptors cell membrane receptors and when are they intracellular? What is a ligand-gated ion channel? What is a ligand? What is a signalling molecule (or just signal molecule) (don't need to know G protein- coupled receptor) b. Transduction - what are relay molecules? What is a phosphorylation cascade? Relate to the "roleplaying" activity we did in class where each volunteer changed their "shape" as a result of "binding" to another (don't need to know the specific molecules involved in transduction, the 2nd messengers such as protein kinases and cAMP) c. Response - describe different types of cellular response, eg what is the role of transcription factors.

13 Describe the 3 stages of cell signalling using the exam.pdf

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Con Excel, haga una ecuacin de regresin lineal mltiple con la ganancia como variable dependiente y el gasto en I+D, los gastos de administracin y el gasto en marketing como variables independientes. Comente sobre la adecuacin del modelo. Identificar los predictores que son significativos. Interpreta el coeficiente de determinacin. Gasto en I+D ($) Administracin ($) Gasto en marketing ($) Beneficio ($) 165349 136898 471784 192262 162598 151378 443899 191792 153442 101146 407935 191050 144372 118672 383200 182902 142107 91392 366168 166188 131877 99815 362861 156991 134615 147199 127717 156123 130298 145530 323877 155753 120543 148719 311613 152212 123335 108679 304982 149760 101913 110594 229161 146122 100672 91791 249745 144259 93864 127320 249839 141586 91992 135495 252665 134307 119943 156547 256513 132603 114524 122617 261776 129917 78013 121598 264346 126993 94657 145078 282574 125370 91749 114176 294920 124267 76254 113867 298664 118474 78389 153773 299737 111313 73995 122783 303319 110352 67533 105751 304769 108734 77044 99281 140575 108552 64665 139553 137963 107404 75329 144136 134050 105734 72108 127865 353184 105008 66052 182646 118148 103282 65605 153032 107138 101005.

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Caso 2: Derrotar al Sistema: tica en Volkswagen En uno de los peores escndalos de tica empresarial de la historia, el mundo se enter en 2015 de que Volkswagen eludi intencionalmente las pruebas gubernamentales de emisiones de escape durante aos al instalar los llamados "dispositivos de desactivacin" en sus vehculos disel limpios. Los investigadores de la Universidad de West Virginia descubrieron por primera vez la violacin cuando comenzaron a estudiar los motores disel limpios. Cuando probaron el rendimiento de los vehculos Volkswagen, se sorprendieron al descubrir que las emisiones en carretera excedan las asignaciones gubernamentales en casi 40 veces. Una investigacin adicional realizada por la Agencia de Proteccin Ambiental de EE. UU. encontr que los vehculos en realidad estaban equipados con un software que esencialmente poda engaar a los sistemas de prueba de emisiones. Los motores disel podran detectar cundo se estn probando las emisiones y cambiar el rendimiento del vehculo para mejorar los resultados de las pruebas. Una vez en la carretera, el vehculo saldra del modo de prueba y emitira un exceso de contaminantes de xido de nitrgeno. Lo que es ms problemtico es la respuesta de Volkswagen al escndalo. La compaa primero sugiri un problema tcnico con los autos, pero finalmente admiti que los dispositivos de software estaban diseados para engaar al sistema. Inicialmente, la compaa inform que solo se vio afectada una cantidad limitada de automviles; sin embargo, a medida que se fueron descubriendo ms detalles, la empresa finalmente admiti que alrededor de 11 millones de automviles en todo el mundo se vieron afectados. Cmo pudo ocurrir una violacin tica tan grave? Puede llevar aos determinar quin tiene la culpa. El director ejecutivo, el Sr. Winterkorn, quien renunci en respuesta al escndalo, inicialmente afirm no saber nada sobre los dispositivos. Si bien muchos ejecutivos de alto rango fueron suspendidos, nadie est seguro de quin conoca o autoriz el software. El director ejecutivo, el Sr. Winterkorn, ha sido descrito como un perfeccionista intransigente que se comprometi a asegurar el primer puesto entre los fabricantes mundiales de automviles. Era conocido por criticar pblicamente a los empleados, y esto generaba miedo entre los empleados y el compromiso de hacer lo que fuera necesario para asegurar el xito de la empresa. La cultura de la empresa ha sido descrita como "segura y despiadada". Preguntas: 2.1 Explique qu factores pueden haber influido en el comportamiento poco tico en Volkswagen. 2.2 En el futuro, qu debe hacer Volkswagen para evitar un problema tico de este tipo en el futuro?.

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Yemek retimi I. Gelecekte gda retimini artrmak iin geerli seeneklerimiz nelerdir? II. Gdada biyoteknoloji kullanmnn balca avantajlar ve sorunlar nelerdir? retme? III.Ktlk ve iddetli aln nedenlerini tartn ve en ok tehdit ettii corafi blgeleri adlandrn. Arazi kullanm I.Toprak dokusunun ana bileeninin zelliklerini adlandrn ve tanmlayn. II.Toprak profilini oluturan farkl katmanlar veya ufuklar nelerdir? Her birini dierlerinden farkl klan nedir? III.Bu blmde listelenen drt ana toprak takmn adlandrn ve tanmlayn. Esas olarak nerede bulunurlar? IV.Bitki kklerinin topraktan almas gereken balca eyler nelerdir? Bitkileri hayatta kalmak iin ihtiya duyduklar miktarlar elde etmekten alkoyabilen (doal veya doal olmayan) bir sreci adlandrn ve tanmlayn. V.Organik gda nedir ve imdi nasl sertifikalandrlyor?.

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Say we have two people waiting for Facebook to approve their marketplace posts. Let Y the the sum of their independent exponential wait times in hours where each wait time rate is 1/2 (1 post is approved every half hour). It will help to recall that there is a special relationship between Exponential and gamma random variables. The sum of n Exp( ) random variables is a gamma (n, ) random variable. Then what is P(Y1) ?.

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A researcher is studying the rII locus of phage T4, which consists of two genes: rIIA and rIIB. Recall that wild-type phage can lyse E. coli K, but that a single rII mutant phage cannot. Three independent rII mutant strains are obtained: 1, 2, and 3. E. coli strain K is coinfected with two rII strains simultaneously and the results are recorded: Infection with 1 and 2 phage = no lysis occurs Infection with 1 and 3 phage = no lysis occurs Infection with 2 and 3 phage = no lysis occurs What can be inferred from these results?.

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A) An asset account. B) A contra asset account. C) A revenue account. D) A contra equity account. E) A liability account. Please use a separate sheet of paper 10 points Prior to May 1, Fortune Company has never had any treasury stock transactions. A company repurchased 100 shares of its common stock on May 1 for $5,000. On July 1 , it reissued 50 of these shares at $52 per share. On August 1 , it reissued the remaining treasury shares at $49 per share. Record the necessary entries for these transactions..

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PP es un nio de 4 aos que acude a la consulta del pediatra con dolor en el odo derecho. INFORMACIN SUBJETIVA Mam dice que su hijo se despert en medio de la noche, llorando, hace 2 noches. Le dio ibuprofeno al nio y l volvi a dormirse. Anoche se despert con dolor y estaba desconsolado. Ella sinti que el mdico debera verlo. Asiste al programa preescolar. Vive con la madre, que fuma en el carro pero no en la casa Padre separado DATOS OBJETIVOS TM parece inflamado: est rojo y puede estar abultado e inmvil T = 100.3 ltimo ibuprofeno hace 3 horas Responda a cada pregunta para el siguiente escenario. Utilice una justificacin para respaldar sus respuestas. 1. Cules son las tres (3) evaluaciones y/o preguntas que seran apropiadas para un paciente que presenta dolor de odo? Use oraciones completas y justifique todas las respuestas. 2. Cules son los tres (3) factores de riesgo asociados con los dolores de odo para este grupo de edad? 3. Describir las diferencias y similitudes entre la otitis media y la otitis externa. Incluya lo que podra esperar subjetiva y objetivamente, responda en oraciones completas y proporcione una justificacin. 4. Cules son 2-3 posibles causas del dolor de odo en este paciente? Utilice una justificacin para respaldar su respuesta..

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Question 1 An Intrusion Detection System (IDS) is a device or software tools or hardware tools that monitor activity to identify malicious or suspicious events. IDS also used to detect unauthorized access to a computer system or network. Figure 1 below shows an example of intrusion detection system. Figure 1 Explain in your own words how the IDS systems work in relation to the FIVE (5) devices below. a) Traffic Server b) Laptop c) 10.0.0.1 d) 10.0.0.19 e) 10.0.0.23.

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