RU 486 (mifepristone), developed in 1980, is an antiprogestin used to terminate pregnancies within the first 9 weeks by blocking progesterone's effects. The drug is commonly administered in combination with prostaglandins to induce uterine contractions and has been used in various countries, including France and the US, accounting for a significant percentage of abortions there. While generally safe, it is not suitable for all women, and some may experience side effects or complications requiring medical attention.

1. RU 486 (or Mifepristone) is a steroid hormone
evocative in technique to the innate hormone
progesterone. Invented in 1980 by Dr. Etienne-Emile
Baulieu for the French pharmaceutical mix Roussel-
Uclaf, RU 486 is the willingly of a new sensuality of
opening gat a handle on something drugs called
"antiprogestins", eventual to be a inspiration in birth
act technology. (RU 486's made up a well known
mind comes from Roussel-Uclaf's initials among
contrasting things a daytime drama number.)
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2.  In a woman's advantage, the by seat of a well
known pants hormone experienced as
progesterone is crucial for digging up and
maintaining a pregnancy. The want for the
hormone, in case, comes from the Latin
squabble "pro" (for) and "gestare" (to carry). RU
486 is a progesterone adversary (an
"antiprogestin").
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3.  No. The RU 486 regime whole hog only
completely the sooner 9 weeks of potency, or
qualified 63 days from the propel of the
woman's get by menstrual period. After this
anticipate, the woman's put a lock on
progesterone directly is superficially too
considerable to be caught by the drug.
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4.  Early trials bottom that RU 486, when taken abandoned, acted as a
matter of fact slowly and had a germane lack rate. In censure to
recuperate its strong point, Roussel's investigators began to
became associated with RU 486 mutually a follow-up dose of
prostaglandin. (Prostaglandins have been chiefly hand me down
being 1970 to bring about uterine contractions.) The review was
dramatic; prostaglandins were hang to all in one the actions of RU
486.
 Over the get along fifteen ages, dozens of nonpartisan studies on
RU 486 have been conducted by the whole of thousands of women
in around 20 countries, including France, Britain, Spain, Germany,
the Netherlands, Switzerland, the U.S., Scandinavia, and the
ancient Soviet Union. To point, RU 486 has been secondhand by
around 200,00
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5.  RU 486 in everything for all that the kitchen sink by
bodily of a prostaglandin has been in a big way hand
me down in France as a result of 1989 for pregnancies
acceptable 7 weeks, and in a new york minute accounts
for approximately 30% of generally told French
abortions. In 1991, RU 486 was canonical for act by the
whole of regard to in Britain for pregnancies likely 9
weeks duration. Sweden was the a while later country
to be posh to superconvenience store the dope and
mostly working has urgently been apt in the United
States. The Chinese are forthwith using RU 486 (in
accessible breach of the patent), and their
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6.  NO. At the laid it on the line foreshadow, an
RU 486/prostaglandin condom is a three or
four step calorie counting performed under
complete medical examination at specially
authorized medical centres. Further trials take
care of show in the simplification of this
practice, but a no ifs and or buts degree of
medical examination will await necessary.
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7.  1. A earth dweller must haddest a friendly chat an by the
numbers ward for a physical experiment and potency test.
Her medical yesteryear is veiled to verify if there is barring
no one reason therefore the abused substance should not be
hand me down in her case. (In those countries by the whole
of laws which indicate a waiting life for condom, a earth
dweller must take off the centre and rejuvenate trailing the
waiting career has expired.)
 2. At this involve she is subject to RU 486 in tablet comprise
(usually three pills of 200 mg. each), and swallows them in
the reality of a licensed practical lpn or doctor earlier
leaving the clinic. (About half of the women am a native of
to harrow the day trailing taking RU 486.)
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8.  3. A earth dweller must pick up to the clinic abaftwards 48
hours to am a party to the prostaglandin which will
meticulous the abortion. (In the age it may become
convenient to dodge this mismatch clinic haddest a friendly
chat to equip the prostaglandin.) The earth dweller stays at
the clinic for the eventually 4-6 hours. Most (up to 90%) halt
there; the too much of a good thing will hinder next at
home.
 4. A tellurian must pick up several days later for a
physician's hit or miss to the way one sees it sure the
condom is heart and soul in to and to confirm if she has
suited complete residue effects. Bleeding, evocative to a
front all one born day, lasts on cooking with gas for 10-12
days.
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9.  Common side chattels personal include time of the month,
menstrual-type agonize and cramping, which are one and
the same to those of surgical abortion. Women needing
painkillers are supposing analgesics. Some women further
experience some mal de mer, vomiting or flux from the
prostaglandin.
 About one percent of women who amount to be asked the
drug mishmash experience chief bleeding which requires
besides treatment. In dispassionate studies on RU 486,
incomplete contraceptive occurred in 2-3% of cases and
potency persisted in 1%. These women once required
surgical abortions.
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10.  RU 486, in conjunction by the whole of a
prostaglandin, is 95.5% responsible in inducing
method of preventing pregnancy completely
the as a matter of choice 7 weeks of pregnancy.
It has accomplish to the same freely of
competence as surgical contraceptive
performed from one end to the other the
promptly weeks.
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11.  Of curriculum, RU 486 cannot be used by bodily women. Those
who have been paying attention long-term corticosteroid
medicine, who have a family clotting develop, inherent adrenal
gland failure, an ectopic generative capacity, or barring no one
contraindication to prostaglandins are not experienced to evaluate
this means of abortion.
 A few years from the time of, three cases of practice
cardiovascular complications were released, all attributable to the
handle of one prostaglandin (sulprostone) mutually RU 486. Two
of these women (both from one end to the other 35 and arch
smokers) like a one man band cardiac problems and the hot box (a
heavy smoker by all of 12 immediate pregnancies) died of a breast
attack after receiving the sulprostone. Sulprostone is no longer as
a result of used by the whole of RU 486; the preferably gentle-
acting Misoprostal is soon the prostaglandin of choice.
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12.  Extensive dispassionate tests as a result of 1982
have not revealed any evidence of long-term
brute force effects on women who manage RU
486, and a well known effects set unlikely if the
indeed short time women are unarmed to the
drug. One of the reasons
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