Preface about Anti Aging Medicine, what it is, who can do this practice and how is the latest news. From many sources, including Prof. dr. Wimpie Pangkahila, Sp.And ' lecturers. Presented in Update Pain Management, Nutrition and Stem Cell Therapy, Solo Paragon, 6th Feb 2016

1. UPDATE ANTI AGING MEDICINE
AND CLINICAL APLICATION
Chandrawati, dr, M.Biomed.AAM

2. Common
belief
• Aging is considered as a “normal” cycle of life that must be
accepted with no argue.
• Destiny
• Therefore in general, aging people accept any dysfunction
as a natural disorder or disease even though it disturbs their
quality of life

3. Can we do something ?
• Aging Aging gracefully • Healthy Aging
However, many basic and clinical data showed that aging process can be
delayed, even reversed

4. Why do we age?

5. 2 Major Problems :

10. As all diseases, aging can be
• Prevented
• Treated
• Reversed
The change of paradigm should
be expressed in the medical
services

12. ANTI AGING IS NOT …..
• Plastic surgery (facelift,
tummy tucks, etc)
• Getting new joints with
orthopedic surgery
• Treating aches and
pains with medication

13. • Expensive laser
treatment
• Anti aging creams
• Bigger breast
• Skinny
• Thick and shiny hair
ANTI AGING IS
more than….

14. Application in daily practice:
• Early detection of aging
process and age-related
disorders or dysfunctions
• Advice or suggestion for
practicing healthy life style
• Replacement therapy:
supplement, hormone,
stem cell therapy in the
next

15. Early detection of aging
process and
age-related disorders or
dysfunctions
should be based on
• signs and symptoms
• physical examination
• Biochemistry tests for
biomarkers of aging

16. One of early signs and
symptoms
of aging process is
sexual dysfunction
• Sexual dysfunctions and other
• sexual problems often cause stress
• and disturb the quality of life

17. Suggestion for practicing
healthy life style
• •enough sleep or rest
• •healthy diet
• •regular exercise
• •avoid toxic substance
• •avoid or manage stress
• •healthy sex

18. Miss Venezuela 2000
Eva Ekvall has died at 28
because of breast cancer
• “We invest a lot of
money in looking
beautiful and not in
health care"
• “There's a huge taboo around breast cancer. But in
this country people get their boobs done every day,
so I don't understand how breast cancer can be a
problem when everybody's showing their breasts"

20. So far, around 24 factors have met the criteria and can be considered
biomarkers. They may be indicated especially for males or for females, and
figures may vary between the sexes.
http://www.anti-aging-plan.com/en/biomarkers_of_aging
1. 17-ketosteroid/ 17-
hydroxycortiosteroid ratio (male)
2. Ascorbic acid
3. Basal Metabolic Rate
4. Blood pressure- pulse
5. Blood pressure- systolic
6. Body Mass Index (female)
7. Caries index
8. Creatinine clearance
9. DHEA-S
10. Fibrinogen
11. Hair baldness (male)
12. Hair grayness
13. Handgrip strength
14. Hemoglobin A1C
15. Lung capacity- FEV1
16. Lung capacity- FVC
17. Maximum oxygen update (male)
18. Near vision
19. Noradrenaline- plasma (male)
20. Peridontal index
21. PSA total (male)
22. Skin elasticity
23. Testosterone free (male)
24. Zinc- serum

22. Replacement therapy
• Treatment can be given to combat all causative
factors of aging process
• The use of certain antioxidant is scientifically
proved to combat free radicals
• Replacement therapy is considered to reverse
decreased level of any substances needed for
optimal function of body system
• Replacement therapy for decreased or deficient
hormones, supplementation of mineral, vitamin, or
other essential substances, and stem cell therapy.

23. New Hope

24. Telomeres & Aging
• It is believed that shortened
telomeres in mitotic (dividing)
cells may be responsible for
some of the changes we
associate with normal aging.

25. How Does Telomerase
Work?
• Some cells are immortal because
their telomerase is switched on
• Examples of immortal cells: blood
cells and cancer cells
• Cancer cells do not age because
they produce telomerase, which
keeps the telomere intact.