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DEPARTMENT OF INTERNAL
MEDICINE
PGI ENDORSEMENT
PATRICIA MARI SORRILLA
SEPT. 20, 2020
M.A
20 year old female
CC: Seizure
HISTORY OF PRESENT ILLNESS
• (+) left ear pain
• (+) fever (undocumented)
• (+)decreased hearing after swimming in the beach
• took unrecalled eardrop, condition resolved in 3 days
HISTORY OF PRESENT ILLNESS
• (+) biparietal headache characterized as:
-dull, persistent with severity of 6-7/10
• (+) nausea and vomiting once a day consisting of
previously ingested food (non bloody)
• (-) fever (-) blurring of vision
• no consult done
• took Ibuprofen 200mg/cap 1 cap once daily with
partial relief
HISTORY OF PRESENT ILLNESS
• (+)persistence of headache, with similar
characteristics,
• (+)still with nausea and vomiting
• (+) fever tmax 38C associated with body malaise and
decreased appetite
• took Co-amoxiclav 1gm/tab 1 tab twice daily but no
relief of fever noted
• no consult done, patient tolerated the condition
HISTORY OF PRESENT ILLNESS
• (+) sudden onset jerky movements of all extremities
lasting for 30 seconds associated with upward rolling
of eyeballs.
• associated with undocumented fever, (+) neck
stiffness
• condition resolved spontaneously, patient was
immediately rushed to the ER
PAST MEDICAL HISTORY
• non hypertensive
• non diabetic
• no previous seizure episode
PERSONAL SOCIAL HISTORY
• student
• non smoker
• occassional alcoholic beverage
drinker
• no illicit drug use
SEXUAL HISTORY
• 1 sexual partner- current boyfriend of 1 year
(boyfriend also claims to be sexually exclusive with gf)
• no history of casual sexual encounters
• no history of STIs
FAMILY HISTORY
• Paternal- stroke, hypertension
• Maternal- DM
• no family history of epilepsy
• no history of sudden cardiac death
PHYSICAL EXAMINATION
• patient was examined drowsy and confused
Vital Signs:
BP 100/60mmHg
HR 83 bpm
RR 20 cpm
O2 95% RA
Temp 36.7
• Weight 50kg
• Height 157cm
• BMI 20.28
PHYSICAL EXAMINATION
• SKIN- warm, dry, good turgor, no rashes
• HEENT-
Head: normocephalic,
Eyes: pink conjunctiva, anicteric sclera, +PERRLA, (-) papilledema
Ears: (-) redness, (-) swelling, intact ear canal and tympanic membrane,
non tender upon palpation
Nose: nasal septum at midline, no sinus tenderness
Mouth: oral mucosa pink, good dentition, tonsilopharyngeal
walls not enlarged, dry lips and tongue
PHYSICAL EXAMINATION
• NECK- (-) neck vein distention, (-) LAD (+) neck rigidity ,
• Chest and lungs: equal chest expansion, clear breath sounds, (-)
wheezing
• Cardiovascular: adynamic precordium, regular, no murmurs, PMI at
5th ICS MCL
• Abdomen: flabby, no visible pulsations, normoactive bowel sounds,
no abdominal bruits, tympanitic , non tender
• Extremities: no edema, no ulcers, warm extremities; brachial, radial,
popliteal, dorsalis pedis, posterior tibial pulses are 2+ and symmetric,
no pulse deficit
NEURO EXAMINATION
• Handedness: Right
• Mental Status: Drowsy, oriented to person but not to place and time,
speech clear and fluent with normal comprehension,
• unable to recall what happened prior to admission,
• able to follow commands
II, III Visual fields full, isocoric pupils 4mm reactive to light
III, IV,
VI
EOM intact, no ptosis, no nystagmus
V Facial sensation equal in all 3 divisions bilaterally
VII Face symmetric with normal eye closure and smile
VIII Hearing normal to rubbing fingers
IX, X Phonation normal
XI Shrugs shoulders bilaterally with equal strength
XII Tongue midline with good movements
• Motor strength: Normal bulk, 5/5 right upper and lower extremities
and left lower extremity, 4/5 left upper extremity
• Sensory: 100% sensation on all extremities
• Reflexes: 2+ and symmetric with plantar reflexes downgoing
• Cerebellar: Rapid alternating movements, finger to nose test and heel
to shin test intact
• Gait: Steady with normal steps, base, arm swing, no pronator drift,
negative Romberg
• Meningeal signs:
• (+) Brudzinski sign,
• (+) Kernig's sign
SUMMARY OF IMPORTANT FINDINGS
• 20 yr old female
• history of ear infection
• (+) biparietal headache 6-7/10
• (+) nausea and vomiting for 2 weeks
• (+) moderate grade fever tmax 38C,
• (+) body malaise (+) dec appetite
• (+) new onset GTC seizure 1 day PTA
lasting for 30 sec
• (+) neck rigidity
• (-) papilledema
• (+) unable to recall what happened
prior to admission
• (+) drowsy
• (+) Brudzinski
• (+) Kernig
IMPRESSION
ACUTE
BACTERIAL
MENINGITIS
BASIS
• 20 years old
• history of ear infection
• (+) biparietal headache 6-7/10
• (+) nausea and vomiting for 2 weeks
• (+) moderate grade fever tmax 38C, (+)
body malaise (+) dec appetite
• (+) new onset GTC seizure 1 day PTA lasting
for 30 sec
• (+) nuchal rigidity
• (+) Brudzinski and Kernig sign
DIFFERENTIAL DIAGNOSIS
RULE IN RULE OUT
1. ENCEPHALITIS - female of reproductive age
- headache 6-7/10
- fever of 1 week
- altered LOC- drowsy and confused
- signs of inc ICP: N&V, drowsy
- GTC seizures
Lumbar puncture to rule out
with PCR
2. BRAIN ABSCESS - history of ear infection
- headache 6-7/10
- fever of 1 week
- signs of inc ICP: N&V, drowsy
- seizures
imaging such as MRI to rule out
3. SUBARACHNOID HEMORRHAGE - headache 6-7/10
- signs of inc ICP: N&V, drowsy
- neck stiffness
imaging such as CT to rule out
DIAGNOSTIC TESTS
CT BRAIN PLAIN
(INSERT VIDEO)
CBS 110 Urinalysis
WBC 29.8 Appearance Yellow,
clear
Seg 90 pH 6.5
Lymph 5 Spgr 1.015
Mono 4 Leukocytes Neg
Eos 1 Blood neg
Baso 0 Protein neg
Hgb 16.2 RBC 2/hpf
Hct 47.5 WBC 0.5/hph
Platelet 363 Epithelial cells 0/hpf
Na 133
Potassium 4.5
Ica 1.12
Mg 2.0
Creatinine 0,96
EGFR 87
ESR 9 mmHr Reference: 0-20 mmHr
SGPT 25 U/L Reference: 12-78 U/L
REVISED IMPRESSION
ACUTE BACTERIAL MENINGITIS
•Admit under the service of IM
•TPR q 4 hrs
•Secure signed consent
•Vital signs q hourly
•NPO temporarily
•Transfer to isolation
•O2 at 2lpm via NC
•IV- PNSS 1L 20gtts/min
• Blood Culture
• Lumbar puncture, gram's stain and culture
• MRI with contrast
• EEG
• start empirical treatment stat with:
• ceftriaxone 2gm IV every 12 hours
• dexamethasone 10mg 1v 20 mins before first dose antibiotices then q6H
thereafter
• vancomycin 1.25gm IV every 12 hours
• acyclovir 500mg IV q8H
• give Valproic Acid (Depakene) 500mg/cap 1 cap twice daily
• elevate head of bed to 30-45 degrees
REVISED IMPRESSION
PNEUMOCOCCAL MENINGITIS
• give Ceftriaxone 2gm IV every 12 hours for 2 weeks
• dexamethasone 10mg IV 15-20 mins before first dose antibiotics,
then every 6 hours thereafter for 4 days
• repeat lumbar puncture after 24-36 hrs of antibiotics
• continue Valproic Acid (Depakene) 500mg/cap 1 cap twice daily
• monitor patient closely

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trixie-final power point presentation acute

  • 1. DEPARTMENT OF INTERNAL MEDICINE PGI ENDORSEMENT PATRICIA MARI SORRILLA SEPT. 20, 2020
  • 2. M.A 20 year old female CC: Seizure
  • 3. HISTORY OF PRESENT ILLNESS • (+) left ear pain • (+) fever (undocumented) • (+)decreased hearing after swimming in the beach • took unrecalled eardrop, condition resolved in 3 days
  • 4. HISTORY OF PRESENT ILLNESS • (+) biparietal headache characterized as: -dull, persistent with severity of 6-7/10 • (+) nausea and vomiting once a day consisting of previously ingested food (non bloody) • (-) fever (-) blurring of vision • no consult done • took Ibuprofen 200mg/cap 1 cap once daily with partial relief
  • 5. HISTORY OF PRESENT ILLNESS • (+)persistence of headache, with similar characteristics, • (+)still with nausea and vomiting • (+) fever tmax 38C associated with body malaise and decreased appetite • took Co-amoxiclav 1gm/tab 1 tab twice daily but no relief of fever noted • no consult done, patient tolerated the condition
  • 6. HISTORY OF PRESENT ILLNESS • (+) sudden onset jerky movements of all extremities lasting for 30 seconds associated with upward rolling of eyeballs. • associated with undocumented fever, (+) neck stiffness • condition resolved spontaneously, patient was immediately rushed to the ER
  • 7. PAST MEDICAL HISTORY • non hypertensive • non diabetic • no previous seizure episode
  • 8. PERSONAL SOCIAL HISTORY • student • non smoker • occassional alcoholic beverage drinker • no illicit drug use
  • 9. SEXUAL HISTORY • 1 sexual partner- current boyfriend of 1 year (boyfriend also claims to be sexually exclusive with gf) • no history of casual sexual encounters • no history of STIs
  • 10. FAMILY HISTORY • Paternal- stroke, hypertension • Maternal- DM • no family history of epilepsy • no history of sudden cardiac death
  • 11. PHYSICAL EXAMINATION • patient was examined drowsy and confused Vital Signs: BP 100/60mmHg HR 83 bpm RR 20 cpm O2 95% RA Temp 36.7 • Weight 50kg • Height 157cm • BMI 20.28
  • 12. PHYSICAL EXAMINATION • SKIN- warm, dry, good turgor, no rashes • HEENT- Head: normocephalic, Eyes: pink conjunctiva, anicteric sclera, +PERRLA, (-) papilledema Ears: (-) redness, (-) swelling, intact ear canal and tympanic membrane, non tender upon palpation Nose: nasal septum at midline, no sinus tenderness Mouth: oral mucosa pink, good dentition, tonsilopharyngeal walls not enlarged, dry lips and tongue
  • 13. PHYSICAL EXAMINATION • NECK- (-) neck vein distention, (-) LAD (+) neck rigidity , • Chest and lungs: equal chest expansion, clear breath sounds, (-) wheezing • Cardiovascular: adynamic precordium, regular, no murmurs, PMI at 5th ICS MCL • Abdomen: flabby, no visible pulsations, normoactive bowel sounds, no abdominal bruits, tympanitic , non tender • Extremities: no edema, no ulcers, warm extremities; brachial, radial, popliteal, dorsalis pedis, posterior tibial pulses are 2+ and symmetric, no pulse deficit
  • 14. NEURO EXAMINATION • Handedness: Right • Mental Status: Drowsy, oriented to person but not to place and time, speech clear and fluent with normal comprehension, • unable to recall what happened prior to admission, • able to follow commands
  • 15. II, III Visual fields full, isocoric pupils 4mm reactive to light III, IV, VI EOM intact, no ptosis, no nystagmus V Facial sensation equal in all 3 divisions bilaterally VII Face symmetric with normal eye closure and smile VIII Hearing normal to rubbing fingers IX, X Phonation normal XI Shrugs shoulders bilaterally with equal strength XII Tongue midline with good movements
  • 16. • Motor strength: Normal bulk, 5/5 right upper and lower extremities and left lower extremity, 4/5 left upper extremity • Sensory: 100% sensation on all extremities • Reflexes: 2+ and symmetric with plantar reflexes downgoing • Cerebellar: Rapid alternating movements, finger to nose test and heel to shin test intact • Gait: Steady with normal steps, base, arm swing, no pronator drift, negative Romberg
  • 17. • Meningeal signs: • (+) Brudzinski sign, • (+) Kernig's sign
  • 18. SUMMARY OF IMPORTANT FINDINGS • 20 yr old female • history of ear infection • (+) biparietal headache 6-7/10 • (+) nausea and vomiting for 2 weeks • (+) moderate grade fever tmax 38C, • (+) body malaise (+) dec appetite • (+) new onset GTC seizure 1 day PTA lasting for 30 sec • (+) neck rigidity • (-) papilledema • (+) unable to recall what happened prior to admission • (+) drowsy • (+) Brudzinski • (+) Kernig
  • 19. IMPRESSION ACUTE BACTERIAL MENINGITIS BASIS • 20 years old • history of ear infection • (+) biparietal headache 6-7/10 • (+) nausea and vomiting for 2 weeks • (+) moderate grade fever tmax 38C, (+) body malaise (+) dec appetite • (+) new onset GTC seizure 1 day PTA lasting for 30 sec • (+) nuchal rigidity • (+) Brudzinski and Kernig sign
  • 20. DIFFERENTIAL DIAGNOSIS RULE IN RULE OUT 1. ENCEPHALITIS - female of reproductive age - headache 6-7/10 - fever of 1 week - altered LOC- drowsy and confused - signs of inc ICP: N&V, drowsy - GTC seizures Lumbar puncture to rule out with PCR 2. BRAIN ABSCESS - history of ear infection - headache 6-7/10 - fever of 1 week - signs of inc ICP: N&V, drowsy - seizures imaging such as MRI to rule out 3. SUBARACHNOID HEMORRHAGE - headache 6-7/10 - signs of inc ICP: N&V, drowsy - neck stiffness imaging such as CT to rule out
  • 21. DIAGNOSTIC TESTS CT BRAIN PLAIN (INSERT VIDEO)
  • 22. CBS 110 Urinalysis WBC 29.8 Appearance Yellow, clear Seg 90 pH 6.5 Lymph 5 Spgr 1.015 Mono 4 Leukocytes Neg Eos 1 Blood neg Baso 0 Protein neg Hgb 16.2 RBC 2/hpf Hct 47.5 WBC 0.5/hph Platelet 363 Epithelial cells 0/hpf
  • 23. Na 133 Potassium 4.5 Ica 1.12 Mg 2.0 Creatinine 0,96 EGFR 87 ESR 9 mmHr Reference: 0-20 mmHr SGPT 25 U/L Reference: 12-78 U/L
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  • 27. •Admit under the service of IM •TPR q 4 hrs •Secure signed consent •Vital signs q hourly •NPO temporarily •Transfer to isolation •O2 at 2lpm via NC •IV- PNSS 1L 20gtts/min
  • 28. • Blood Culture • Lumbar puncture, gram's stain and culture • MRI with contrast • EEG
  • 29. • start empirical treatment stat with: • ceftriaxone 2gm IV every 12 hours • dexamethasone 10mg 1v 20 mins before first dose antibiotices then q6H thereafter • vancomycin 1.25gm IV every 12 hours • acyclovir 500mg IV q8H • give Valproic Acid (Depakene) 500mg/cap 1 cap twice daily • elevate head of bed to 30-45 degrees
  • 30.
  • 32. • give Ceftriaxone 2gm IV every 12 hours for 2 weeks • dexamethasone 10mg IV 15-20 mins before first dose antibiotics, then every 6 hours thereafter for 4 days • repeat lumbar puncture after 24-36 hrs of antibiotics • continue Valproic Acid (Depakene) 500mg/cap 1 cap twice daily • monitor patient closely