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Annals of Clinical and Medical
Case Reports
Case Report ISSN 2639-8109 Volume 8
Treatment of Deep Burn Wounds of the Buttocks and perineum using Vacuum Sealing
Drainage Combined with a Homemade Anal Canal
Guo F1
, Chen Z2
, Song J2
, Wang LU2
and Cheng H3*
1
Department of Plastic and Reconstruction surgery, Zhongda Hospital, Southeast University, 87 Dingjiaqiao street. Nanjing, Jiangsu
Province, China
2
Department of Medical, Southeast University, 87 Dingjiaqiao street. Nanjing, Jiangsu Province, China
3
Department of Plastic and Reconstruction surgery, Huai’an first people Hospital, Nanjing medical University, 6 Beijing Western,
Huai’an, Jiangsu Province, China
*
Corresponding author:
Hongyu Cheng,
Department of Plastic and Reconstruction
surgery, Huai’an first people Hospital, Nanjing
medical University, 6 Beijing Western, Huai’ an,
Jiangsu Province, China, Tel: 8615195354045;
Fax: +8602583272212;
E-mail: chenghongyu5566@163.com
Received: 20 Feb 2022
Accepted: 04 Mar 2022
Published: 11 Mar 2022
J Short Name: ACMCR
Copyright:
©2022 Cheng H. This is an open access article distribut-
ed under the terms of the Creative Commons Attribution
License, which permits unrestricted use, distribution, and
build upon your work non-commercially.
Citation:
Cheng H, Treatment of Deep Burn Wounds of the But-
tocks and perineum using Vacuum Sealing Drainage
Combined with a Homemade Anal Canal. Ann Clin Med
Case Rep. 2022; V8(13): 1-5
Keywords:
Vacuum sealing drainage; Burn; Anal canal
http://www.acmcasereport.com/ 1
1. Abstract
The aim of this study was to investigate the therapeutic effects
of vacuum sealing drainage technology combined with home-
made anal canal treating the deep burn wounds of the buttocks and
perineum. From March 2014 to September 2019, after debride-
ment of buttocks and perineal granulation wounds in 10 cases with
large-area deep burns, autologous postage stamp skin was grafted,
homemade silicone tube was inserted and fixed in the anus, contin-
uous catheterization was performed, and the wounds were treated
with vacuum sealing drainage technique for 5-7 days. In 9 cases,
most of the skin survived, and the wound was healed after chang-
ing the dressing. Treating deep burn wounds on the buttocks and
perineum with VSD technique and anal insertion of homemade
canal significantly improved the skin grafting survival effect, re-
duced the number of operations and complication, and shortened
the treatment time.
2. Introduction
In patients with large area deep burns, the wounds on limbs and
trunk can be easily healed by surgical excision, escharectomy and
skin grafting, and the wounds on perineum and buttock are gen-
erally treated by final operation [1]. Due to the special location,
it is not easy to bandage and fix after skin grafting, and there are
often contaminated wounds with urine and feces, which brings
many difficulties to the treatment [2, 3]. After decrustation, the
wound required multiple skin grafts to heal. From March 2014 to
September 2019, we admitted and successfully treated 10 patients
of large-area deep burns with buttocks and perineal granulation
wounds by vacuum sealing drainage (VSD) technology combined
with a homemade anal canal.
3. Materials and Methods
From March 2014 to September 2019, 10 patients (6 males, 4 fe-
males) in total with perineal and buttocks deep burns were includ-
ed in this study. Inclusion criteria were the presence of 50%–90%
total burn area and is in deep partial thickness burns or the third
degree burns (the diagnostic criteria for the burn area are based
on the Chinese role of nines, and the depth diagnostic criteria are
based on the rule of three degrees and four levels). The age of pa-
tients was between 19 and 45 years, with a mean age of 29.6 years.
Of these, 2 cases were chemical burns, 5 were molten steel burns,
and 3 were scalded by boiled water. All patients had severe burns
of both lower extremities with their scalp was complete, and the
admission time for all patients was 1 hour to 1 day after the injury.
All patients were routinely treated with fluid replacement to pre-
vent shock after admission, as well as anti-infective and nutrition-
al support treatment. Patients with inhalation injury or burns over
70% were treated with preventive tracheotomy. After the shock
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Volume 8 Issue 13 -2022 Case Report
stage, the escharectomy and skin grafting on the limbs and trunk
were performed several times. The scalp was often used as a donor
site to provide the skin graft. The wounds of limbs and trunk on
the first stage healed gradually. The wounds of the buttocks and
perineum were protected in the early stage, and the escharecto-
my was used in the later dressing change. After repeated dressing
changes, the necrotic tissue of the wounds of buttocks and perine-
um completely fell off, and the granulation grew well, and thus,
the skin grafting was prepared (Figure S1).
Figure S1: Skin Grafting
Mannitol 250 ml was orally administered for catharsis 1 night be-
fore surgery, and the patient was given enema and catheterization
in the morning of the operation, and placed in the prone position
after the general anesthesia was stable. Subsequently, thorough-
ly clean the wound surface in strict according to the principle of
debridement, repeatedly wash the wound surface with hydrogen
peroxide, dilute iodophor and a large amount of normal saline,
and perform routine iodophor disinfection. Firstly, 1000 ml of nor-
mal saline containing 1/1000000 epinephrine was injected under
the scalp, and about 3% of the thin skin graft was excised with a
roller-type peeling knife and then the donor site was bandaged.
The removed skin graft was cut into a size of 0.5 cm×0.5 cm and
evenly attached to the buttock and perineum wounds. Secondly,
a silicone tube with a 24 Fr was taken from the thoracic closed
drainage tube (Henan Ruike Medical Instrument Co., Ltd.), cut
it into the 30-cm long segment, smooth both ends, and used as an
anal tube. One end was lubricated with paraffin oil, and inserted
7–10 cm into the patient's anus. then, the silicone tube was firmly
fixed to the anus by stitching twice with the 1st thread. Thirdly,
multiple VSD dressings (Wuhan Vsd Medical Science & Technol-
ogy Co., Ltd.) are designed according to the shape and size of the
wound. The drainage tubes were combined in series to reduce the
number of outlet tubes for convenient sealing, and the direction of
the drainage tube was faced to the head side. The designed VSD
dressing is covered on the wound surface and fixed with skin sta-
pler. All VSD drains were combined into one outlet (Figure S2)
and the surrounding skin was cleaned. Take the semipermeable
film, remove the backing paper on the adhesive surface, keep the
film flat, paste the semipermeable film layer by layer from the skin
healed to the skin graft using the "Stacking Technique". Pay atten-
tion not to press the VSD dressing when sticking the film, so as not
to squeeze the liquid in the dressing to the skin around the wound
surface and affect the adhesion. When properly pasted, remove the
supporting film on the back. Notably, the perineal anal canal and
catheter around the paste should be appropriate, and paste mul-
tiple layers to facilitate the fixation of the exposed pipeline. The
coverage edge of semipermeable film around the wound shall be
more than 2 cm from the skin healed to ensure the sealing effect. If
normal skin is lacking around the wound, the silver alginate dress-
ing (Kanglebao Co., Ltd.) can be attached to the wound surface,
and the wound surface will be sealed by adhering VSD film on the
outside. Whether the seal is reliable can be seen from the sunken
VSD dressing due to the suction of the negative pressure.
After the operation, the patient was placed in the floating bed or
turn over nursing bed, the continuous central negative pressure
was immediately connected, the negative pressure was adjusted to
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Volume 8 Issue 13 -2022 Case Report
30~ 40kPa, and the drainage volume was observed and recorded.
The intravenous infusion of sensitive antibiotics was selected ac-
cording to the drug sensitivity test. The patient was administered a
fluid diet or nasal feeding, using 15 g of senna soaked in water was
convenient to make the stool pasty. On day 2 after operation, the
patient was given enema with 300 ml warm normal saline twice
a day from the anal canal. If the VSD drainage tube was blocked
after the operation, the sterile syringe could be used to retrogradely
inject normal saline from the orifice for irrigation. The VSD dress-
ing and the anal canal was removed at 5-7 days after operation and
the wound was treated with dressing change.
Figure S2: VSD drains
4. Results
A total of 10 patients received skin grafting on buttock and perine-
um wound to cover VSD dressing and insert anal canal: the VSD
dressing was opened 5 days after operation in 1 case, 6 days after
operation in 7 cases and 7 days after operation in 2 cases. Six cases
of the skin grafts survived more than 80% while three cases sur-
vived more than 70%, and the residual scattered wounds healed
spontaneously after dressing change. In one case, more than 50%
survived skin grafts were observed, and 1 week after wound dress-
ing change, further reoperation and VSD dressing were conducted
for wound healing (Figure S3). In this group, the shortest hospi-
talization time was 15 days and the longest was 35 days, with an
average healing time of 21 days.
Figure S3: VSD dressing were conducted for wound healing
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Volume 8 Issue 13 -2022 Case Report
5. Discussion
Because the deep burn wound of buttock and perineum is suscepti-
ble to infection caused by fecal and urinary contamination, it often
requires multiple operations, skin grafting and compression dress-
ing, to make the skin graft survive and the wound heal [4, 5].At the
same time, it is not easy to fix the skin graft after grafting on the
wound surface, often making the survival rate of the skin graft low.
In the present clinical study, a self-made anal canal was inserted
into the anus, while catheterization was retained, and VSD was
placed after skin grafting of the wound. The results showed that
the overall efficacy of VSD technique in the treatment of patients
with skin transplantation was satisfactory, with few intraopera-
tive and postoperative complications, high survival rate of wound
skin grafting, and corresponding reduction in hospitalization time.
These findings are consistent with the findings of other authors
assessing the benefit of VSD in large area cutaneous defects treat-
ment[6].
VSD technique is a novel therapy to promote wound healing and
has been widely used in trauma, general surgery, and burn depart-
ments in recent years[7-10]. VSD is a closed system that can ful-
ly extract the exudate, necrotic tissue and toxin generated by the
wound surface through the negative pressure formed, so that the
free skin graft is closely attached to the granulation tissue of the
wound surface[11, 12]. Simultaneously, the pressure generated by
VSD coverage on the wound surface is uniform and consistent,
avoiding the effect of uneven stress on skin survival[13]. The ap-
plication of algal silver dressing to cover the edge of wound sur-
face before VSD dressing can make the wound edge well sealed.
It may be that this material is a absorbent dressing, which is easy
to keep dry and firmly adhere to the wound surface after water
absorption.
The buttock wound is adjacent to the anus and is easily contaminat-
ed with feces during defecation, so patients cannot defecate with
the anus during treatment. Considering the many complications
of long-term total parenteral nutrition (TPN)[14, 15], we chose a
silicone tube with a 24 Fr caliber, which was processed to make an
anal canal. One end was lubricated with paraffin oil and inserted
into the patient's anus and fixed to the anus by suturing to prevent
slippage of the anal canal. The perianal space was subsequently
closed to reduce fecal flow to the wound. After operation, a liquid
diet was orally administered to reduce stool formation[16]. Simul-
taneous oral administration of small doses of laxatives facilitates
fecal excretion to minimizes contamination. Lavation is conduct-
ed regularly to prevent fecal residue. If pseudomonas aeruginosa
infection occurs after surgery, 5% Sulfamethoxazole solution is
utilized for washing the wound daily through the VSD drainage
tube[17, 18]. If the other bacterial infections are considered, the
wound can also be rinsed repeatly with 0.25% diluted iodophor sa-
line. Several aspects should be paid attention to in the use of VSD
in the treatment of deep burn wounds of the buttock and perineum:
(1) Although VSD technique can timely remove exudate and ne-
crotic tissue in the drainage area, it cannot replace debridement.
Therefore, thorough preoperative debridement is necessary [19].
(2) VSD technique should be avoided in patients with coagulopa-
thy, and anticoagulants should be avoided during treatment.
6. Declaration of Interest Statement
For all the authors none are declared.
References
1. Merchant N, Boudana D. Management of adult patients with buttock
and perineal burns: The Ross Tilley Burn Centre experience. J Trau-
ma Acute Care Surg. 2014; 77(4): 640-688.
2. Jeschke MG, Bar MEV, Choudhry MA. Burn injury. Nat Rev Dis
Primers. 2020; 6(1): 11.
3. Bordes J, Goutorbe P, Asencio Y. A non-surgical device for faecal
diversion in the management of perineal burns. Burns. 2008; 34(6):
840-844.
4. Potokar T, Ramaswamy R, Dickson WA. Isolated buttock burns:
epidemiology and management. Burns. 2001; 27(6): 629-634.
5. Azmy AA. Perianal burns in children: a plan of management. Burns
Incl Therm Inj. 1987; 13(5): 419-420.
6. Li Z. Effect of vacuum sealing drainage in dermatoplasty of large
area of cutaneous defects. Int J Surg. 2017; 42: 143-146.
7. Teng SC. Use of negative pressure wound therapy in burn patients.
Int Wound J. 2016; 13 Suppl 3(Suppl 3): 15-18.
8. Ren Y, Chang P, Sheridan LR. Negative wound pressure therapy is
safe and useful in pediatric burn patients. Int J Burns Trauma. 2017;
7(2): 12-16.
9. Lin DZ, Kao YC, Chen C. Negative pressure wound therapy for
burn patients: A meta-analysis and systematic review. Int Wound J.
2021; 18(1): 112-123.
10. Cahill C, Fowler A, Williams LJ. The application of incisional neg-
ative pressure wound therapy for perineal wounds: A systematic re-
view. Int Wound J. 2018; 15(5): 740-748.
11. Lalezari S, Lee CJ, Borovikova AA. Deconstructing negative pres-
sure wound therapy. Int Wound J. 2017; 14(4): 649-657.
12. Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during
negative pressure wound therapy: does the wound VAC enhance bac-
terial clearance? Ann Plast Surg. 2004; 52(3): 279-80.
13. Peng L, Eltgroth ML, LaTempa TJ. The effect of TiO2 nanotubes on
endothelial function and smooth muscle proliferation. Biomaterials.
2009; 30(7): 1268-1272.
14. Demircan M, Gurunluoglu K, Karaman A. Damaging Effects of To-
tal Parenteral Nutrition Formula on Vascular Endothelium. J Pediatr
Gastroenterol Nutr. 2015; 61(4): 464-468.
15. Trivic I, Misak Z, Kerman V. Central Catheter-related Bloodstream
Infection Rates in Children on Home Parenteral Nutrition. J Pediatr
Gastroenterol Nutr. 2020; 70(3): e59-e62.
16. Rutan RL. Management of perineal and genital burns. J ET Nurs.
1993; 20(4): 169-176.
http://www.acmcasereport.com/ 5
Volume 8 Issue 13 -2022 Case Report
17. Cardozo C. Antibiotic selection in the treatment of acute invasive
infections by Pseudomonas aeruginosa. Guidelines by the Spanish
Society of Chemotherapy. Rev Esp Quimioter. 2019; 31(1): 78-100.
18. Mizdal CR, Stefanello ST. Molecular docking, and anti-biofilm ac-
tivity of gold-complexed sulfonamides on Pseudomonas aerugino-
sa. Microb Pathog. 2018; 125: 393-400.
19. Edmondson SJ, Ali IJ, Murray A. Time to start putting down the
knife: A systematic review of burns excision tools of randomised
and non-randomised trials. Burns. 2018; 44(7): 1721-1737.

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Treatment of deep burn wounds of the buttocks and perineum using vacuum sealing drainage combined with a homemade anal canal

  • 1. Annals of Clinical and Medical Case Reports Case Report ISSN 2639-8109 Volume 8 Treatment of Deep Burn Wounds of the Buttocks and perineum using Vacuum Sealing Drainage Combined with a Homemade Anal Canal Guo F1 , Chen Z2 , Song J2 , Wang LU2 and Cheng H3* 1 Department of Plastic and Reconstruction surgery, Zhongda Hospital, Southeast University, 87 Dingjiaqiao street. Nanjing, Jiangsu Province, China 2 Department of Medical, Southeast University, 87 Dingjiaqiao street. Nanjing, Jiangsu Province, China 3 Department of Plastic and Reconstruction surgery, Huai’an first people Hospital, Nanjing medical University, 6 Beijing Western, Huai’an, Jiangsu Province, China * Corresponding author: Hongyu Cheng, Department of Plastic and Reconstruction surgery, Huai’an first people Hospital, Nanjing medical University, 6 Beijing Western, Huai’ an, Jiangsu Province, China, Tel: 8615195354045; Fax: +8602583272212; E-mail: chenghongyu5566@163.com Received: 20 Feb 2022 Accepted: 04 Mar 2022 Published: 11 Mar 2022 J Short Name: ACMCR Copyright: ©2022 Cheng H. This is an open access article distribut- ed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and build upon your work non-commercially. Citation: Cheng H, Treatment of Deep Burn Wounds of the But- tocks and perineum using Vacuum Sealing Drainage Combined with a Homemade Anal Canal. Ann Clin Med Case Rep. 2022; V8(13): 1-5 Keywords: Vacuum sealing drainage; Burn; Anal canal http://www.acmcasereport.com/ 1 1. Abstract The aim of this study was to investigate the therapeutic effects of vacuum sealing drainage technology combined with home- made anal canal treating the deep burn wounds of the buttocks and perineum. From March 2014 to September 2019, after debride- ment of buttocks and perineal granulation wounds in 10 cases with large-area deep burns, autologous postage stamp skin was grafted, homemade silicone tube was inserted and fixed in the anus, contin- uous catheterization was performed, and the wounds were treated with vacuum sealing drainage technique for 5-7 days. In 9 cases, most of the skin survived, and the wound was healed after chang- ing the dressing. Treating deep burn wounds on the buttocks and perineum with VSD technique and anal insertion of homemade canal significantly improved the skin grafting survival effect, re- duced the number of operations and complication, and shortened the treatment time. 2. Introduction In patients with large area deep burns, the wounds on limbs and trunk can be easily healed by surgical excision, escharectomy and skin grafting, and the wounds on perineum and buttock are gen- erally treated by final operation [1]. Due to the special location, it is not easy to bandage and fix after skin grafting, and there are often contaminated wounds with urine and feces, which brings many difficulties to the treatment [2, 3]. After decrustation, the wound required multiple skin grafts to heal. From March 2014 to September 2019, we admitted and successfully treated 10 patients of large-area deep burns with buttocks and perineal granulation wounds by vacuum sealing drainage (VSD) technology combined with a homemade anal canal. 3. Materials and Methods From March 2014 to September 2019, 10 patients (6 males, 4 fe- males) in total with perineal and buttocks deep burns were includ- ed in this study. Inclusion criteria were the presence of 50%–90% total burn area and is in deep partial thickness burns or the third degree burns (the diagnostic criteria for the burn area are based on the Chinese role of nines, and the depth diagnostic criteria are based on the rule of three degrees and four levels). The age of pa- tients was between 19 and 45 years, with a mean age of 29.6 years. Of these, 2 cases were chemical burns, 5 were molten steel burns, and 3 were scalded by boiled water. All patients had severe burns of both lower extremities with their scalp was complete, and the admission time for all patients was 1 hour to 1 day after the injury. All patients were routinely treated with fluid replacement to pre- vent shock after admission, as well as anti-infective and nutrition- al support treatment. Patients with inhalation injury or burns over 70% were treated with preventive tracheotomy. After the shock
  • 2. http://www.acmcasereport.com/ 2 Volume 8 Issue 13 -2022 Case Report stage, the escharectomy and skin grafting on the limbs and trunk were performed several times. The scalp was often used as a donor site to provide the skin graft. The wounds of limbs and trunk on the first stage healed gradually. The wounds of the buttocks and perineum were protected in the early stage, and the escharecto- my was used in the later dressing change. After repeated dressing changes, the necrotic tissue of the wounds of buttocks and perine- um completely fell off, and the granulation grew well, and thus, the skin grafting was prepared (Figure S1). Figure S1: Skin Grafting Mannitol 250 ml was orally administered for catharsis 1 night be- fore surgery, and the patient was given enema and catheterization in the morning of the operation, and placed in the prone position after the general anesthesia was stable. Subsequently, thorough- ly clean the wound surface in strict according to the principle of debridement, repeatedly wash the wound surface with hydrogen peroxide, dilute iodophor and a large amount of normal saline, and perform routine iodophor disinfection. Firstly, 1000 ml of nor- mal saline containing 1/1000000 epinephrine was injected under the scalp, and about 3% of the thin skin graft was excised with a roller-type peeling knife and then the donor site was bandaged. The removed skin graft was cut into a size of 0.5 cm×0.5 cm and evenly attached to the buttock and perineum wounds. Secondly, a silicone tube with a 24 Fr was taken from the thoracic closed drainage tube (Henan Ruike Medical Instrument Co., Ltd.), cut it into the 30-cm long segment, smooth both ends, and used as an anal tube. One end was lubricated with paraffin oil, and inserted 7–10 cm into the patient's anus. then, the silicone tube was firmly fixed to the anus by stitching twice with the 1st thread. Thirdly, multiple VSD dressings (Wuhan Vsd Medical Science & Technol- ogy Co., Ltd.) are designed according to the shape and size of the wound. The drainage tubes were combined in series to reduce the number of outlet tubes for convenient sealing, and the direction of the drainage tube was faced to the head side. The designed VSD dressing is covered on the wound surface and fixed with skin sta- pler. All VSD drains were combined into one outlet (Figure S2) and the surrounding skin was cleaned. Take the semipermeable film, remove the backing paper on the adhesive surface, keep the film flat, paste the semipermeable film layer by layer from the skin healed to the skin graft using the "Stacking Technique". Pay atten- tion not to press the VSD dressing when sticking the film, so as not to squeeze the liquid in the dressing to the skin around the wound surface and affect the adhesion. When properly pasted, remove the supporting film on the back. Notably, the perineal anal canal and catheter around the paste should be appropriate, and paste mul- tiple layers to facilitate the fixation of the exposed pipeline. The coverage edge of semipermeable film around the wound shall be more than 2 cm from the skin healed to ensure the sealing effect. If normal skin is lacking around the wound, the silver alginate dress- ing (Kanglebao Co., Ltd.) can be attached to the wound surface, and the wound surface will be sealed by adhering VSD film on the outside. Whether the seal is reliable can be seen from the sunken VSD dressing due to the suction of the negative pressure. After the operation, the patient was placed in the floating bed or turn over nursing bed, the continuous central negative pressure was immediately connected, the negative pressure was adjusted to
  • 3. http://www.acmcasereport.com/ 3 Volume 8 Issue 13 -2022 Case Report 30~ 40kPa, and the drainage volume was observed and recorded. The intravenous infusion of sensitive antibiotics was selected ac- cording to the drug sensitivity test. The patient was administered a fluid diet or nasal feeding, using 15 g of senna soaked in water was convenient to make the stool pasty. On day 2 after operation, the patient was given enema with 300 ml warm normal saline twice a day from the anal canal. If the VSD drainage tube was blocked after the operation, the sterile syringe could be used to retrogradely inject normal saline from the orifice for irrigation. The VSD dress- ing and the anal canal was removed at 5-7 days after operation and the wound was treated with dressing change. Figure S2: VSD drains 4. Results A total of 10 patients received skin grafting on buttock and perine- um wound to cover VSD dressing and insert anal canal: the VSD dressing was opened 5 days after operation in 1 case, 6 days after operation in 7 cases and 7 days after operation in 2 cases. Six cases of the skin grafts survived more than 80% while three cases sur- vived more than 70%, and the residual scattered wounds healed spontaneously after dressing change. In one case, more than 50% survived skin grafts were observed, and 1 week after wound dress- ing change, further reoperation and VSD dressing were conducted for wound healing (Figure S3). In this group, the shortest hospi- talization time was 15 days and the longest was 35 days, with an average healing time of 21 days. Figure S3: VSD dressing were conducted for wound healing
  • 4. http://www.acmcasereport.com/ 4 Volume 8 Issue 13 -2022 Case Report 5. Discussion Because the deep burn wound of buttock and perineum is suscepti- ble to infection caused by fecal and urinary contamination, it often requires multiple operations, skin grafting and compression dress- ing, to make the skin graft survive and the wound heal [4, 5].At the same time, it is not easy to fix the skin graft after grafting on the wound surface, often making the survival rate of the skin graft low. In the present clinical study, a self-made anal canal was inserted into the anus, while catheterization was retained, and VSD was placed after skin grafting of the wound. The results showed that the overall efficacy of VSD technique in the treatment of patients with skin transplantation was satisfactory, with few intraopera- tive and postoperative complications, high survival rate of wound skin grafting, and corresponding reduction in hospitalization time. These findings are consistent with the findings of other authors assessing the benefit of VSD in large area cutaneous defects treat- ment[6]. VSD technique is a novel therapy to promote wound healing and has been widely used in trauma, general surgery, and burn depart- ments in recent years[7-10]. VSD is a closed system that can ful- ly extract the exudate, necrotic tissue and toxin generated by the wound surface through the negative pressure formed, so that the free skin graft is closely attached to the granulation tissue of the wound surface[11, 12]. Simultaneously, the pressure generated by VSD coverage on the wound surface is uniform and consistent, avoiding the effect of uneven stress on skin survival[13]. The ap- plication of algal silver dressing to cover the edge of wound sur- face before VSD dressing can make the wound edge well sealed. It may be that this material is a absorbent dressing, which is easy to keep dry and firmly adhere to the wound surface after water absorption. The buttock wound is adjacent to the anus and is easily contaminat- ed with feces during defecation, so patients cannot defecate with the anus during treatment. Considering the many complications of long-term total parenteral nutrition (TPN)[14, 15], we chose a silicone tube with a 24 Fr caliber, which was processed to make an anal canal. One end was lubricated with paraffin oil and inserted into the patient's anus and fixed to the anus by suturing to prevent slippage of the anal canal. The perianal space was subsequently closed to reduce fecal flow to the wound. After operation, a liquid diet was orally administered to reduce stool formation[16]. Simul- taneous oral administration of small doses of laxatives facilitates fecal excretion to minimizes contamination. Lavation is conduct- ed regularly to prevent fecal residue. If pseudomonas aeruginosa infection occurs after surgery, 5% Sulfamethoxazole solution is utilized for washing the wound daily through the VSD drainage tube[17, 18]. If the other bacterial infections are considered, the wound can also be rinsed repeatly with 0.25% diluted iodophor sa- line. Several aspects should be paid attention to in the use of VSD in the treatment of deep burn wounds of the buttock and perineum: (1) Although VSD technique can timely remove exudate and ne- crotic tissue in the drainage area, it cannot replace debridement. Therefore, thorough preoperative debridement is necessary [19]. (2) VSD technique should be avoided in patients with coagulopa- thy, and anticoagulants should be avoided during treatment. 6. Declaration of Interest Statement For all the authors none are declared. References 1. Merchant N, Boudana D. Management of adult patients with buttock and perineal burns: The Ross Tilley Burn Centre experience. J Trau- ma Acute Care Surg. 2014; 77(4): 640-688. 2. Jeschke MG, Bar MEV, Choudhry MA. Burn injury. Nat Rev Dis Primers. 2020; 6(1): 11. 3. Bordes J, Goutorbe P, Asencio Y. A non-surgical device for faecal diversion in the management of perineal burns. Burns. 2008; 34(6): 840-844. 4. Potokar T, Ramaswamy R, Dickson WA. Isolated buttock burns: epidemiology and management. Burns. 2001; 27(6): 629-634. 5. Azmy AA. Perianal burns in children: a plan of management. Burns Incl Therm Inj. 1987; 13(5): 419-420. 6. Li Z. Effect of vacuum sealing drainage in dermatoplasty of large area of cutaneous defects. Int J Surg. 2017; 42: 143-146. 7. Teng SC. Use of negative pressure wound therapy in burn patients. Int Wound J. 2016; 13 Suppl 3(Suppl 3): 15-18. 8. Ren Y, Chang P, Sheridan LR. Negative wound pressure therapy is safe and useful in pediatric burn patients. Int J Burns Trauma. 2017; 7(2): 12-16. 9. Lin DZ, Kao YC, Chen C. Negative pressure wound therapy for burn patients: A meta-analysis and systematic review. Int Wound J. 2021; 18(1): 112-123. 10. Cahill C, Fowler A, Williams LJ. The application of incisional neg- ative pressure wound therapy for perineal wounds: A systematic re- view. Int Wound J. 2018; 15(5): 740-748. 11. Lalezari S, Lee CJ, Borovikova AA. Deconstructing negative pres- sure wound therapy. Int Wound J. 2017; 14(4): 649-657. 12. Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bac- terial clearance? Ann Plast Surg. 2004; 52(3): 279-80. 13. Peng L, Eltgroth ML, LaTempa TJ. The effect of TiO2 nanotubes on endothelial function and smooth muscle proliferation. Biomaterials. 2009; 30(7): 1268-1272. 14. Demircan M, Gurunluoglu K, Karaman A. Damaging Effects of To- tal Parenteral Nutrition Formula on Vascular Endothelium. J Pediatr Gastroenterol Nutr. 2015; 61(4): 464-468. 15. Trivic I, Misak Z, Kerman V. Central Catheter-related Bloodstream Infection Rates in Children on Home Parenteral Nutrition. J Pediatr Gastroenterol Nutr. 2020; 70(3): e59-e62. 16. Rutan RL. Management of perineal and genital burns. J ET Nurs. 1993; 20(4): 169-176.
  • 5. http://www.acmcasereport.com/ 5 Volume 8 Issue 13 -2022 Case Report 17. Cardozo C. Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa. Guidelines by the Spanish Society of Chemotherapy. Rev Esp Quimioter. 2019; 31(1): 78-100. 18. Mizdal CR, Stefanello ST. Molecular docking, and anti-biofilm ac- tivity of gold-complexed sulfonamides on Pseudomonas aerugino- sa. Microb Pathog. 2018; 125: 393-400. 19. Edmondson SJ, Ali IJ, Murray A. Time to start putting down the knife: A systematic review of burns excision tools of randomised and non-randomised trials. Burns. 2018; 44(7): 1721-1737.