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August 2009Vol. 34, Number 2
Abroadand
hereathome,
scientistsmoveus
closertoacure.
A publication of the American Tinnitus Association
2 Tinnitus Today | August 2009
Hello. I’m the same Lisa, now with my married
name of Hutton!
Thank You for Taking ATA’s Member Survey
We are very grateful to the 1,137 members
who responded to our online Member Survey!
Your thoughts are an important element in
ATA remaining an informed and successful
organization. Look for survey results at
www.ata.org later this summer and in the
December 2009 Tinnitus Today.
Selected Survey Highlights
Please see some early survey results
on page 4 of this issue.
ATA’s Support Network
Check out the updated listings
at www.ata.org or contact me at
lisa@ata.org or (800) 634-8978 x219
to learn more. We send e-mail
updates to inform and remind our
members of upcoming support group
meetings, including those with guest
speakers. We send other important ATA updates as
well. Please call or e-mail me if you would like to
add your e-mail address to the list.
National Tinnitus Awareness Week (TAW)
The 2009 TAW activities truly reflected its theme,
“What YOU Can Do To Cure Tinnitus.” Individuals
in their own towns, cities and states celebrated
TAW, raising awareness about tinnitus and the
urgent need for a cure. A few TAW activities
included:
n 	 ATA held its first ever Walk For A Cure
(see page 14) and “Hope & Help for Living
With Tinnitus,” a seminar, (see page 10) in
Southern California on May 16 – both events
organized by dedicated volunteers.
Members Corner
Lisa F. Hutton, ATA Manager of Member Services
n 	 Earl O. Hutchinson, political activist, tinnitus
sufferer and radio personality, interviewed
Scott C. Mitchell, J.D., ATA’s recent past board chair,
on “The Hutchinson Report,” broadcast on radio
station 1460 AM in Los Angeles and streamed
on KTYM.com. Scott addressed ATA’s mission
to cure tinnitus. The interview is available at
www.ata.org/news-pubs.
n 	 ATA honored its Congressional Champions
(see page 18).
n 	 Linda Beach, co-coordinator of the South New
Jersey Tinnitus Support Group, and her husband,
State Senator Jim Beach (D-NJ 6th District), cham-
pioned the Tinnitus Awareness Week resolution
declared in New Jersey’s state legislature.
Your Members Section and
Health Professional Updates
Visit your Tinnitus Information
Center in the Members Section –
www.ata.org/members – with its
robust archive of Tinnitus Today
articles and all the health profes-
sionals on ATA’s listing. We recently
added icons (at right) to the listing
to accurately reflect each health
care professional and/or clinic’s
type of ATA membership.
ATA does not award professional
credentials, so please consider our
listing as a starting point rather than a referral list. We
include information provided by various professionals
so that you can contact them and select someone
whose services best fit your needs. We update the
listings on a regular basis and when available, provide
a link to a professional’s Web site where they often list
their training and treatment options in more detail.
Research Champions
Professional Members
ATA member
As ATA members, you
are the cornerstone
of our organization
and the reason for our
commitment to a cure.
Again, thank you for
your ongoing support
of our mission and
for renewing your
ATA membership.
3August 2009 | Tinnitus Today
Editorial and advertising office: American Tinnitus Association, P.O. Box 5, Portland, OR 97207 • (503) 248-9985, (800) 634-8978 • tinnitus@ata.org • www.ata.org
Michael Malusevic, Executive Director
Nina Rogozen, Editor
Tinnitus Today is published three times a year, in April,August and
December, and mailed to American Tinnitus Association members
and donors. Circulation is rotated to 75,000 annually.
The American Tinnitus Association is a nonprofit human health
and welfare agency under 26 USC 501(c)(3).
©2009 American Tinnitus Association. No part of this publication
may be reproduced, stored in a retrieval system or transmitted in
any form, or by any means, without the prior written permission of
the Publisher. ISSN: 0897-6368 (print). ISSN: 1530-6569 (online).
Board of Directors
Gary P. Reul, Ed.D., Chair, Issaquah, Wash.
Mark K. Johnson, J.D., Vice Chair, Anchorage, Alaska
Barbara Kennedy, Secretary, Mays Landing, N.J.
J. Scott Simons, Treasurer, Sioux Falls, S.D.
Anthony T. Cacace, Ph.D., Detroit, Mich.
Neil Cherian, M.D., Cleveland Heights, Ohio
James O. Chinnis Jr., Ph.D., Warrenton, Va.
Michelle Dapolito, Hoboken, N.J.
Marsha Johnson, Au.D., FAAA, Portland, Ore.
Thomas J. Lobl, Ph.D., Valencia, Calif.
Scott C. Mitchell, J.D., C.P.A., Houston, Texas
Michael O’Rourke, Arlington, Va.
Michael J. A. Robb, M.D., Phoenix, Ariz.
Joseph Trevisani, New York, N.Y.
Honorary Directors
Peter & Joan Graves, Beverly Hills, Calif.
Mark O. Hatfield, U.S. Senate-Retired, Washington, D.C.
William Shatner, Los Angeles, Calif.
Jack A. Vernon, Ph.D., Portland, Ore.
Scientific Advisory Committee
Anthony T. Cacace, Ph.D., Chair, Detroit, Mich.
Paul J. Abbas, Ph.D., Iowa City, Iowa
Thomas J. Brozoski, Ph.D., Springfield, Ill.
Donald Caspary, Ph.D., Springfield, Ill.
Craig Formby, Ph.D., CCC-A, Tuscaloosa, Ala.
Donald A. Godfrey, Ph.D., Toledo, Ohio
James (Jay) W. Hall III, Ph.D., FAAA, Gainesville, Fla.
James Henry, Ph.D., Portland, Ore.
James A. Kaltenbach, Ph.D., Cleveland, Ohio
Paul R. Kileny, Ph.D., FASHA, Ann Arbor, Mich.
Robert A. Levine, M.D., Boston, Mass.
Craig W. Newman, Ph.D., Cleveland, Ohio
Jay F. Piccirillo, M.D., FACS, St. Louis, Mo.
Michael J. A. Robb, M.D., Phoenix, Ariz.
Jay T. Rubinstein, M.D., Ph.D., Seattle, Wash.
Roger A. Ruth, Ph.D., Charlottesville, Va.
Susan Shore, Ph.D., Ann Arbor, Mich.
Hinrich Staecker, M.D., Ph.D., Kansas City, Kan.
The Publisher reserves the right to reject or edit any manuscript received for publication, and to reject any advertising deemed unsuitable
for Tinnitus Today. Acceptance of advertising by Tinnitus Today does not constitute endorsement of the advertiser, its products or services,
nor does Tinnitus Today make any claims or guarantees as to the accuracy or validity of the advertiser’s offer. The opinions expressed by
contributors to Tinnitus Today are not necessarily those of the Publisher, editors, staff or advertisers.
The American Tinnitus Association exists to cure tinnitus through
the development of resources that advance tinnitus research.
August 2009Vol. 34, Number 2
TABLE OF CONTENTS
REGULAR FEATURES
4	 Passing the Baton: I’ve Had a Wonderful Year as CEO
	 Gary P. Reul, Ed.D.
6	 Letters to the Editor
24	 Questions and Answers
	 Jack Vernon, Ph.D.
26	 Special Donors and Tributes
SPECIAL FEATURES
2	 Members Corner
	 Lisa F. Hutton, ATA Manager of Member Services
5	 New Board Transitions at ATA
	 Katie Fuller, ATA Executive and Development Associate
8	 Family Series: Adaptability Helps the Reuls Live with Acoustical Trauma
	 Nina Rogozen, Editor, Tinnitus Today
10	 Hope and Help for Living with Tinnitus: A Seminar Recap
11	 Can a Simple Kiss on the Ear Cause Auditory Problems?
	 Levi A. Reiter, Ph.D.
14	 A Walk in the Park and Across America
16	 The Incidence of Tinnitus in U.S. Veterans Continues to Escalate
18	 Honoring New Friends in our Nation’s Capital
	 Jennifer DuPriest, ATA Associate Executive Director
FOCUS ON RESEARCH
12	 Highlights: Selected 2008-2009 Tinnitus Research Studies
	 Nina Rogozen, Editor, Tinnitus Today and
	 Daniel Born, ATA Director of Research and Special Projects
17	 ATA Member Participates in Tinnitus Clinical Trial:
	 A Q&A with Mark Church about rTMS
	 Daniel Born, ATA Director of Research and Special Projects and
	 Jennifer DuPriest, ATA Associate Executive Director
20	 Tinnitus and Hyperactivity in Dorsal Cochlear Nucleus Fusiform
	 Paul G. Finlayson, Ph.D.
21	 Clinical Trial of Acamprosate for Tinnitus
	 William Hal Martin, Ph.D., and Yong-Bing Shi, M.D., Ph.D.
4 Tinnitus Today | August 2009
Passing the Baton: I’ve had a Wonderful Year as CEO
Selected Highlights from the 2009 Member Survey
Gary P. Reul, Ed.D., Chair, ATA Board of Directors
I am very pleased to announce
that on July 1, 2009, ATA named
Michael Malusevic as the new
Executive Director and Jennifer
DuPriest as Associate Executive
Director. (This represents a change
in leadership titles.) Michael and
Jennifer have been with ATA for
quite some time and share a strong
commitment to our mission and to
the smooth, effective running of
this wonderful organization. As
chair of the board, I look forward
to continuing to work with Michael,
Jennifer and the entire staff over the
coming years. Go to www.ata.org
to read more about these exciting
changes.
My heartfelt parting words are
simple, but important: Please con-
tinue supporting ATA so our goal
of a cure becomes a reality for all
of us. Simply use the convenient
envelope in the center of Tinnitus
Today or go to www.ata.org and
click on “Donate Now.”
I believe that during my tenure as
CEO, I fulfilled the board’s expec-
tations and I look forward to my
second retirement. This change
will accommodate my health chal-
lenges and eliminate frequent and
extended commuting between
Portland, Ore. and Seattle, Wash.
However, I am not leaving ATA,
only changing positions.
On July 1, 2008, I was poised to
become chair of ATA’s Board of
Directors. As fate, luck or karma
would have it, the board asked me
to become the organization’s Chief
Executive Officer (CEO) on June
28, 2008. They agreed that I had
the right experience, with 20 years
as an administrator and a doctorate
in leadership, to step into the role.
At 71 years of age, I have had a
life full of work experiences; being
ATA’s CEO was the most reward-
ing and satisfying. Of particular joy
was directing such an experienced
and talented staff; interacting with
so many people with tinnitus from
all over the world; and working
with a great board and its very
skilled chair, Scott C. Mitchell, J.D.
I am pleased that my tinnitus and
hyperacusis allowed many members
to feel a kinship with me. I thank
all of those who sent me notes or
e-mails and those with whom I had
interesting telephone conversations
about tinnitus.
Top three things members
want from ATA:
n	 A cure for tinnitus
n	 Ways to manage tinnitus
n	 Advocacy efforts with national
lawmakers and leaders
Greatest sources of tinnitus
information:
n	 Tinnitus Today
n	 www.ata.org
Most helpful sections
of Tinnitus Today:
n	 Research articles
n	 Treatment articles
n	 Coping and managing tinnitus
n	 Q&A
Most common tinnitus effects
on day-to-day life:
n	 Annoying
n	 Trouble sleeping
n	 Trouble concentrating
Tinnitus sounds like:
n	 Ringing
n	 Hissing
n	 Buzzing
n	 High-tension wire
Responders with hearing loss:
n	 73 percent
Gender of survey responders:
n	 Male – 71 percent
n	 Female – 29 percent
5August 2009 | Tinnitus Today
New Board Transitions at ATA
Katie Fuller, ATA Executive and Development Associate
She says that her favorite part of
being a board member has been
visiting Portland, Ore. (ATA’s head-
quarters) and developing ways to
deal with tinnitus. Maggie plans
on “being involved with ATA as
long as they put up with me.”
A Warm Welcome to ATA’s
New Board Members
Michelle Dapolito, Director of
Marketing at FX Solutions in
Saddle River, N.J.,
joined the board
July 1. Michelle
has over 12 years
experience in
online marketing
and advertising and Web site
design. Before coming on as a
director, Michelle volunteered her
time to help ATA’s Web committee
revamp our site, www.ata.org, and
continues to be instrumental in its
changes and further development.
We are pleased to have Michelle’s
contagious energy and commitment
to the organization on board.
We also welcome Marsha Johnson,
Au.D., FAAA, a practicing audiol-
ogist in Portland who founded the
Oregon Tinnitus
and Hyperacusis
Clinic in 1997.
Marsha brings
to ATA over ten
years of clinical
knowledge and experience in
caring for patients with tinnitus,
hyperacusis and/or hearing loss.
Her sincere desire to help those
who are suffering will prove indis-
pensable to the organization.
A New Chair
July 1, the start of the 2009-2010
fiscal year, brought major changes
to ATA’s Board of
Directors. As he
addresses in his
farewell column
(see “Passing the
Baton,” page 4)
Gary P. Reul, Ed.D.,
has stepped down as ATA’s Chief
Executive Officer and rejoined the
board as chair.
A Huge Thank You
Scott C. Mitchell, J.D., just com-
pleted three dedicated years as
chair of ATA’s
Board of Directors.
“With my term as
board chair coming
to a close,” reflects
Scott, “I must say
that it has been a privilege to work
with the ATA staff. To paraphrase
Winston Churchill, ‘Never have
so many been helped so much by
so few.’ Gary’s move from CEO
to chair of the board assures me
that ATA will continue to focus on
finding a tinnitus cure, and in the
meantime, provide compassion-
ate help to those who are suffer-
ing. With our staff, and Gary still
involved in leadership, we could
not be in better hands.”
ATA thanks Scott for his excellent
years as chair and the extraordi-
nary time and effort he donated
on behalf of ATA and the tinnitus
research community. We are very
pleased that Scott is continuing to
work with ATA as a board director.
A Fond Farewell to Two Long-
Standing Board Members
John R. Bates and Margaret
(Maggie) F. Peak, Ph.D., have
been on the Board of Directors for
a combined total of twelve years.
John leaves after
serving for six
years, two of them
also on the finance
committee. He is
currently presi-
dent and CEO of Flint Resources
Company, LLC, in Tulsa, Okla.,
whose principal subsidiary is com-
mercial construction, building large
projects, such as schools, hospitals
and stadiums throughout the south-
ern, southwestern and western
United States. John says that the
best part of serving on ATA’s board
was having the opportunity to
work with extremely professional
board members, staff and research-
ers. When asked how long he plans
on being involved with ATA, John
says, “We don’t have ‘the cure’
[yet] so the job is not finished.
Therefore, I will stay involved
through ATA’s Advisory Council.”
Margaret (Maggie) F. Peak, Ph.D.,
has been involved with ATA since
1975. She is a
champion of
tinnitus suffer-
ers, particularly
veterans, and has
helped guide the
organization’s focus toward fund-
ing research and developing the
Roadmap to a Cure. Maggie is the
Assistant Chief of Audiology and
Speech Pathology at VA Gulf Coast
Veterans Health Care System in
Biloxi, Miss., where she splits her
time between seeing patients and
managing the department’s admin-
istrative operations.
6 Tinnitus Today | August 2009
Letters to the Editor
Alternative Tinnitus Treatments
I am a 52-year-old man who has been living with
severe tinnitus for over 25 years. Exposure to loud
music, when I was a rock guitarist in my 20s, caused
my tinnitus. I also have genetic hearing loss (my
father and grandfather were hard of hearing in their
later years). For the last year, I have been wearing
hearing aids.
I originally went to a doctor in California who told
me that there was nothing that could be done. The
with my tinnitus. Meditation and personal growth
work did the most good.
Recently, I went to a doctor who works with
Quantum Health, a diagnostic computer system
designed to identify energy imbalances, food sensi-
tivities/allergies and other risk factors. He gave me
a long list of foods to avoid and a plethora of herbs,
vitamins and minerals, which I adhered to for six
weeks. I could only eat turkey, green vegetables and
a few fruits. I had to avoid everything else, including
various spices, oils, caffeine, dairy, alcohol and sugar.
After the six weeks, I felt physically better than I
have ever felt – I had tons of energy and felt mentally
clear and very strong. At the same time I was doing
this Quantum Health diet, I went to see a highly
recommended Chinese acupuncturist and spiritual
healer. Within a few weeks – and I don’t know how
or why – I no longer needed my hearing aids. I still
experience ringing in my ears, which has not signifi-
cantly improved, but my hearing definitely has.
I would like to see professionals give these alterna-
tive approaches a chance and even research their
effectiveness in treating tinnitus.
Lon Cohen
Marina del Rey, Calif.
One Woman’s Positive Experience
with Psychotherapy
Eye Movement Desensitization and Reprocessing
(EMDR) is a powerful method of psychotherapy.
Practitioners use it for a wide variety of problems. I
have been seeing a psychotherapist in Chicago who
is on the forefront of using EMDR for tinnitus.
I have had tinnitus for twenty years. Initially the
sound was similar to a smoke alarm going off; then
it seemed like a million cicadas; and now it is akin
to a teakettle. Like others, my original ear, nose and
throat doctor (ENT) told me to either “deal with it
or go crazy.” I dealt with it and by the fall of 2008, I
noticed an alarming increase in my ringing. I actually
In each issue, we include letters from our members about their experi-
ences with tinnitus and with non-traditional treatments. We do so in
the hope that the information offered might help our readers. Please
read these anecdotal reports carefully.When we include letters about
treatments, consult with your physician or health care advisor and
decide for yourself if a given treatment might be right for you.As
always, the opinions expressed are strictly those of the letter writers
and do not reflect an opinion of or endorsement by ATA.
Send your letters to Nina Rogozen, Editor at nina@ata.org or to
Editor, Tinnitus Today, ATA, P.O. Box 5, Portland, OR 97207.
best I could hope for was to protect what hearing I
had left. More recently I was shocked and dismayed
to find, that after 25 years, no one I spoke with had
any information whatsoever with regard to alterna-
tive healing methods. They knew nothing about
diet, acupuncture, cranial sacral work, meditation,
chakra clearing, visualization, psychotherapy, holis-
tic healing or any other alternative treatments. I had
tried all of these methods to some degree with vary-
ing levels of success, at least with regard to coping
7August 2009 | Tinnitus TodayATA does not endorse or recommend any tinnitus products or treatments.
Advertisement
ended up in the emergency
room due to Lyrica®, the
medication erroneously
prescribed for a separate,
misdiagnosed condition,
which made my tinnitus
uncontrollable.
That same fall, my new
ENT referred me for EMDR
treatments. My initial ses-
sions began with an imag-
ined environment – a calm
location where I could start
to mentally decrease my
tinnitus sounds. Sessions
after that included color
association, breathing
techniques, visualization/
meditation and eye movement exercises resulting in
decreased anxiety. I also learned to take the power
away from my tinnitus; to stimulate the right and left
sides of my brain; and many other tools to decrease
both the sound and stress of my tinnitus. EMDR has
made a significant difference in my lifestyle and
coping mechanisms. I am able to use the many tools I
learned from my sessions.
I have noticed a differ-
ence in my condition
since beginning EMDR
treatment. I can manage
it better and although I
still notice some sound
fluctuations, my anxiety
has decreased. I’m glad
to be sharing this infor-
mation with others who
suffer with tinnitus.
Donna Marsh
Orland Park, Ill.
Editor’s note: EMDR is a form of psychotherapy
developed to help resolve symptoms resulting
from disturbing and unresolved life experiences.
It includes a comprehensive and integrative
psychotherapy approach. Read more at
www.emdr.com/briefdes.htm.
8 Tinnitus Today | August 2009
Gary and Barbara Reul enjoy traveling. They’ve
been to 52 countries, most recently to China and
Sweden. Like most of us, they bring home remind-
ers of their adventures. But one day in 1993, they
brought back something from Florida that neither
of them expected – Gary’s debilitating tinnitus and
hyperacusis (a decreased tolerance to some normal
sounds that makes them seem unbearably loud).
Barbara, a travel agent, heard about a great-sound-
ing Florida Everglades experience – an airboat ride
to a quiet spot with beautiful birds and animals. The
travel brochure did not mention the boat’s extremely
loud engine and horn or the risk of tinnitus and
hyperacusis, which struck Gary on the spot. That
night, without the acoustical distractions on the
street, the quiet of their hotel punctuated Gary’s
agony. “I felt like a caged animal; I was climbing the
walls,” he remembers. “I paced and held my head
while a high-pitched noise filled my ears.”
Tinnitus and Hyperacusis Changed
Their Lives
Many of Gary’s friends did not understand the prob-
lem, which left him feeling very alone with his new
disability. At work he endured large, intolerably
noisy meetings by sitting in the hallway. “I had to
constantly explain to people why I was there,” says
Gary. “However, this was a learning experience for
others and it drew out many who had tinnitus.”
“At first Gary’s problems were very stressful,”
remembers Barbara. “I felt frustrated and often on
the verge of tears. I blamed myself for arranging the
airboat ride and felt guilty for not experiencing these
problems myself. This was the roller coaster ride of
our lives, which seemed like a blur of depression.”
That fateful trip robbed the Reuls of some activities
they had always enjoyed together. At first, Barbara
would not leave Gary at home and venture out to
plays, movies or other places his ears could not tol-
erate. No more Super Bowl parties, church, baseball
games, weddings, funerals or movies. “We can’t talk
in the car because I have to wear earmuffs if we go
over twenty miles an hour,” laments Gary. “This
struggle is also very painful because Gary looks the
A Series on Families
Living With Tinnitus
We often have little influence on a loved
one’s chronic condition. However, we can
learn about the issues, remain supportive
and take care of our own well-being. For
some, working to enhance treatments, find
cures and raise awareness are ways to cope
and create hope. This is certainly true in
the tinnitus community.
This is the third story in our series on
families made up of members with and
without tinnitus. The series explores their
experiences, the feelings that penetrate
their lives and the frustrations they face.
It also illuminates some of the solutions
that diminish their stress and allow
families to settle into a “new normal.”
Adaptability Helps
the Reuls Live with
Acoustical Trauma
By Nina Rogozen, Editor, Tinnitus Today
9August 2009 | Tinnitus Today
same, so some friends still don’t really understand,”
says Barbara.
Gary Turned to the American Tinnitus
Association
Part of the Reuls’ frustration has been the lack of
treatment options. Doctor after doctor told Gary to
“live with it.” He took an antidepressant, which
helped for a while. He tried herbal medications,
including Ginkgo biloba for two years, which did
not give him any relief. Counseling helped some
and Tinnitus Retraining Therapy (TRT) helped his
hyperacusis, but not his tinnitus.
Desperate for guidance, Gary contacted the
American Tinnitus Association for emotional support
and informed resources. He eagerly absorbed infor-
mation in brochures and archived articles and on
CDs. He shared these resources with his family, who
were anxious to understand. His involvement with ATA
grew as Gary served as chair of ATA’s program commit-
tee, vice chair of the Board of Directors, ATA’s CEO for
the 2008-2009 fiscal year and now chair of the board.
Developing a New Normal
“We have adapted to a new normal, a way of living
altered from our pre-tinnitus years, yet one that gives
us as much satisfaction as possible,” says Barbara. “We
aim for an acceptable balance between what I do and
what he can’t do.” Gary has encouraged Barbara’s
“emancipation” from her hesitancy to enjoy activities
without him. Gary is not without the stress of tinnitus
and hyperacusis, but his and Barbara’s adaptability
and their dedication to each other’s happiness is the
engine that created their new normal. What seemed to
help the Reuls the most was time to adjust to lifestyle
changes. Gary uses earplugs and earmuffs to keep out
loud sounds he cannot tolerate. Lecturing about tinnitus
and hyperacusis at their retirement community helps
him as well.
The Gift of Experience
The Reuls have some good ideas that may help those
of you with tinnitus in your family. If you are living
with hyperacusis and crave silence, as most of us do,
remember that being in the midst of some noise may
actually help you become
less sensitive to sound. Try
going to hotel restaurants,
which tend to be quieter,
as are many eating estab-
lishments between 2 p.m.
– 5 p.m. And call ahead to
inquire about quiet seat-
ing. If you are anxious and/
or depressed, discuss the
possible use of medication
with your health care pro-
fessional. Always keep ear-
plugs or earmuffs nearby. Use them when necessary,
for instance, like Gary does around his playful grand-
daughter. Ask your dentist to drill for 10 seconds, stop
for 10 seconds, etc. to reduce noise trauma. “Use ATA
materials to educate others about what you are hearing
and experiencing,” concludes Gary. Barbara adds, ”Be
as calm and understanding as possible.”
Committed to Each Other and All of Us
Gary and Barbara believe in ATA’s mission and under-
stand personally how important everyone’s support is
to bolstering tinnitus and hyperacusis research that will
lead us to a cure. They encourage all families and indi-
viduals to contribute to this very important cause.
“Wehaveadaptedtoanewnormal,
awayoflivingalteredfromour
pre-tinnitusyears,yetonethatgives
usasmuchsatisfactionaspossible.”
~ Barbara Reul
To contribute to ATA’s mission
of silencing tinnitus, simply use
the envelope in the center of
Tinnitus Today. Remember, what
may seem like a small contri-
bution makes a big difference
toward curing tinnitus.
Gary and Barbara Reul at The Bund (Waitan), one
of the most recognizable architectural symbols of
Shanghai, China, located at the west bank of a
bend in the Huangpu River.
10 Tinnitus Today | August 2009
The Los Angeles Tinnitus Support Group cel-
ebrated its 25th anniversary in a way consistent
with its ongoing focus – providing help and
hope to tinnitus sufferers. On May 16, 2009, led
by support group leader Nelly Nigro, the group
commemorated its 25 years of service by deliver-
ing “Hope and Help for Living with Tinnitus,”
a public seminar held at the VA Greater Los
Angeles Healthcare System. The daylong seminar,
sponsored by the American Tinnitus Association
and supported by House Ear Institute and
Advanced Bionics, featured an impressive list of
tinnitus experts. They covered a variety of sub-
jects, including current tinnitus research, existing
therapies, development of novel technologies,
tinnitus in the military, ATA-supported research
and the Roadmap to a Cure. Also discussed were
drug therapies, drug development and practical
strategies to effectively manage one’s tinnitus.
Additionally, the event recognized Nelly Nigro for
her many years of service to ATA and the support
group, and Mr. D.G. Gumpertz for his financial
contribution to the seminar and his ongoing com-
mitment to and support of ATA’s mission.
Our deepest thanks to Nelly Nigro
and D.G. Gumpertz for their leader-
ship and support. And a heartfelt
thank you to our speakers:
Jim Boswell, Ph.D.,
CEO, House Ear Institute
Jeff A. Carroll, Ph.D.,
Director, Tinnitus and Hypercusis
Treatment Center, University of
California, Irvine
Dhyan Cassie, Au.D., FAAA,
Ear, Nose and Throat
Professional Associates
Hamid R. Djalilian, M.D.,
Associate Professor of Clinical
Otolaryngology and Director of the
Division of Neurotology and Skull
Base, University of California,
Irvine Medical Center
Jennifer DuPriest,
Associate Executive Director, ATA
John W. House, M.D.,
President, House Ear Institute
Thomas J. Lobl, Ph.D.,
VP of Research &
Development, NeuroSystec
Corporation and member,
ATA Board of Directors
David I. Meyer, Ph.D.,
Executive VP of Research,
House Ear Institute
Scott C. Mitchell, J.D.,
recent past chair,
ATA Board of Directors
Eric Viirre, M.D., Ph.D.,
Associate Adjunct Professor of
Surgery, Division of Otoloaryngology,
University of California, San Diego
“Hope and Help for Living with Tinnitus”: A Seminar Recap
Left: Scott C. Mitchell, J.D., recent past chair, ATA Board of Directors and Nelly Nigro, chair, seminar planning
committee and Los Angeles Tinnitus Support Group leader. Center: John W. House, M.D., House Ear Institute.
Right: Jennifer DuPriest, Associate Executive Director, ATA, and Marcia Harris, first Los Angeles Tinnitus
Support Group leader.
Dan Burbach is a welcome addi-
tion to the ATA staff. He became
our fulfillment coordinator in the
winter of 2009, soon after we
moved to our new offices. Dan is
in charge of ATA mailings, product
sales shipments and data entry. He
has a drive to make ATA’s distribution function even
more fluid and continually flexible.
Dan graduated from the University of Oregon in 2005
with a double major in political science and art. His
experiences in college led him toward a path in the
nonprofit world and motivated him to give back to
the community. He spent a year and a half working
for Habitat for Humanity through AmeriCorps in
New Orleans, La. and Biloxi, Miss. When not working,
Dan is out exploring his neighborhood, traveling,
reading and enjoying time with friends and family.
Welcome to Dan Burbach, ATA’s Fulfillment Coordinator
11August 2009 | Tinnitus Today
Although ear kissing has
undoubtedly been around
as long as humans, the sur-
prisingly pathologic result
of this simple gesture first
appeared in print as recently
as August 2008.3
The initial case involved
a four-year-old child who
hugged her mom and gave
her a loving smooch on her left ear canal. Mom’s
immediate experience was severe, deep ear pain;
loud, screeching tinnitus; total hearing loss; and
facial twitching in the region of the ear – all on the
left side. Within the next several hours, her total
hearing loss recovered to a stable 35 dB SNHL in
the middle hearing frequencies. The loss remains at
that level two and a half years later. The patient con-
tinued to suffer from tinnitus and facial spasms for
about one year. During that time she also developed
hyperacusis and distortion in the clarity of her hear-
ing in the left ear. Today, the SNHL, hyperacusis and
distortion remain. The tinnitus is now noticeable pri-
marily in quiet surroundings, and the facial spasms
occur only after experiencing excessively loud noise
at a wedding, live concert or other noisy venue.
This first case study
received a good deal of
media coverage, and as
a result, dozens of people
came forth with their very
similar stories. One indi-
vidual was given a happy
Mother’s Day “peck”
on the ear by her loving
husband, only to suffer
immediate hearing loss,
tinnitus and hyperacusis.
In another case, a parent
received a traditional, but
misdirected, farewell kiss
on the cheek by her son-
in-law, which inadvertent-
ly landed on her ear. The
Can a Simple Kiss on the Ear
Cause Auditory Problems?
result was SNHL, tinnitus and hyperacusis.
To date, I have examined over one dozen cases rang-
ing from 10 to 81 years of age. All show the same
three symptoms: SNHL, tinnitus and hyperacusis.
There are three intriguing questions that I would
like to address:
1. If this phenomenon is so old and so common, why
has it taken so long to be discovered and published?
2. What is it about a kiss to the ear that causes such
devastating consequences?
3. What can be done to treat or prevent this problem?
The answer to the first question is professional
denial. Each patient who contacted me to have an
ear-kiss injury evaluated, confided that a physician
had previously denied their claim that a kiss caused
their hearing problem. When several patients came
across my “kiss” research, they felt validated – no,
they were not imagining things. Their doctors’ pre-
conceived notions about the harmlessness of a kiss
had prevented further investigation into the matter
via scientific or medical research.
The second question regards the cause of this ear
pathology, which has
been termed “REKS”
for Reiter’s Ear-Kiss
Syndrome.4
Research
indicates that a kiss to
the ear canal creates
suction, which pulls the
eardrum and ossicular
chain (small inner-ear
bones that transmit
sound) forward. This
in turn pulls the stapes
(one of the ossicular
chain) away from the
inner ear, causing a
tsunami-like turbulence
in the inner ear fluids.
This damages the
Levi A. Reiter, Ph.D., Hofstra University, Hempstead, New York
The answer to the question posed by this title is an unfortunate “yes!” Tinnitus, hyperacusis and
permanent sensorineural hearing loss (SNHL) can result from a single, affectionate kiss to the ear.1,2
Levi A. Reiter, Ph.D.
continued on page 25
12 Tinnitus Today | August 2009
Tinnitus Research: Tales From a
Grand Meeting at Grand Island, N.Y.1
United States, December 2008
Anthony T. Cacace, Ph.D., is the recent past editor of
the American Journal of Audiology and chair of ATA’s
Scientific Advisory Committee. In his words, “Scientific
conferences play an important role in updating
knowledge and improving our conceptualizations of
selected topics of interest. They are a healthy way
for promoting discussion/debate and providing seg-
ues for the advancement of science.” In June 2007
the conference, “Advances in Tinnitus Assessment,
Treatment and Neuroscience Basis,” was a huge
success. Scientists from Belgium, Canada, China,
Finland, Germany, Italy, Japan, South America and
the United States attended and participated in the
exchange of knowledge, research programs and
enthusiasm.
Six prominent researchers, representing their indi-
vidual research teams, presented papers published in
the December 2008 issue of the American Journal of
Audiology. Topics included: (1) The dorsal cochlear
nucleus (DCN) may play a pivotal role in tinnitus
development; (2) Anatomical and neurobiological evi-
dence of auditory/somatosensory system interactions;
(3) Synaptic plasticity at the level of the DCN can serve
as a mechanism for tinnitus generation and tinnitus
may be a multisensory phenomenon; (4) Using a gap
detection startle-reflex procedure in rats to demonstrate
behavioral evidence of tinnitus and perhaps hyperacu-
sis; (5) The cortical representation of tinnitus is mani-
fested by increased synchrony between sets of neurons;
and (6) Identifying subgroups of tinnitus patients as a
way to improve treatment outcomes. Cacace sums up
the value of such a conference: “… The convergence
of the basic sciences and the clinical domain … can
contribute to advancing this area.”
Highlights: Selected 2008-2009
Tinnitus Research Studies
Nina Rogozen, Editor, Tinnitus Today and Daniel Born, ATA Director of Research and Special Projects
Identifying Tinnitus Subgroups to
Maximize Treatment2
United States, December 2008
Richard Tyler, Ph.D., and his research team began
with the premise that it is “important to uncover
tinnitus subgroups to identify subsets of patients
most likely to benefit from different treatments.”
By reviewing strategies for subgrouping based on
etiology, subjective reports, the audiogram, psychoa-
coustics, imaging and cluster analysis, they obtained
preliminary results. The team’s analysis of 246
participants helped them determine 26 categorical
and 25 continuous variables. Results suggested
four major patient subgroups – those who have
(1) constant, distressing tinnitus; (2) varying
tinnitus that is worse in noisy environments;
(3) learned to manage their condition
and whose tinnitus is not influ-
enced by touch (somatic modula-
tion); and (4) tinnitus that is worse
in quiet environments. The team
concluded that it is possible to
identify subgroups of tinnitus
patients using statistical approaches.
Potential follow up would explore
clinical tinnitus treatment trials based
on utilizing subgroup analysis.
Comparing Different Frequencies of Daily
Repetitive Transcranial Magnetic Stimulation
for Treating Tinnitus 3
Egypt, February 2008
Repetitive transcranial magnetic stimulation (rTMS)
(see page 17) uses different frequencies – 1 Hz,
10 Hz, 25 Hz and sham (occipital, 1 Hz) – to treat
tinnitus. To better understand the effects of these
Once again we bring you our yearly sampling of tinnitus research being conducted in the United States
and abroad. Each study gives us hope that we are moving closer and closer to the foundations of better
treatments, and ultimately a cure. This year, we include a glossary of words and phrases to make it
easier to understand some of the more technical references in this review (see page 23). You will find
these items italicized in the body of the text below.
13August 2009 | Tinnitus Today
various frequencies, Eman M. Khedr, M.D., and his
research team randomly divided 66 patients, all
with chronic tinnitus, into four treatment groups.
All patients received daily rTMS treatment over
their left temporoparietal cortex, a region of the
brain known to be involved in speech perception,
for two weeks. The team assessed them using
the Tinnitus Handicap Inventory, self-ratings of
symptoms and audiometric measures of residual
inhibition. The researchers found, before and after
treatment during the next four months, no signifi-
cant differences in basal measures or responses
to different frequencies of rTMS among the four
groups. Responses depended on tinnitus duration:
those participants who had tinnitus for the longest
period of time responded least to treatment. The
investigators concluded that daily sessions of rTMS
over the temporoparietal cortex may be a potentially
useful tinnitus treatment.
Heidelberg Model of Evidence-Based
Music Therapy4
Germany, July 2008
More than a half-million patients in Germany who
need tinnitus treatment suffer from tonal tinnitus
(tinnitus with a well-defined frequency). Heike
Argstatter, Ph.D., and her research team held the
opinion that though tinnitus is one of the most
common symptoms in ear, nose and throat (ENT)
medicine, its treatments are polypragmatic and
often lack scientific foundation. They developed
a novel music therapy and substantiated it with
psychological, audiological and functional imaging
procedures. They believe the advantages of this
therapy are the integration of known and well
proven acoustic and psychotherapeutic techniques
converted to resonance training, neuroauditive
cortex reprogramming and tinnitus desensitization.
The team found the music therapy an effective
treatment for 190 patients with chronic tonal tinnitus
and highly advantageous to treatment duration,
effectiveness and follow-up stability compared with
customary interventions. Brain imaging strongly
suggests the usefulness of further investigation and
discussion of neuronal tinnitus modeling.
Acute High-Intensity Sound Exposure Alters
Responses of Place Cells in Hippocampus5
United States, March 2009
Overstimulation is known to activate neural plastic-
ity (the brain’s ability to adapt to new conditions)
in the auditory nervous system causing changes
in function and re-organization in brain systems.
Previous research demonstrated that overstimula-
tion, using high-intensity noise or tones, can induce
signs of tinnitus. Here, Timothy J. Goble, Ph.D.,
and his team utilized rat studies to show that over-
stimulation causes changes in the way a subset
of hippocampal pyramidal neurons (place cells)
respond as rats search for rewards in a spatial maze.
In familiar environments, place cells respond when
the animal moves through specific locations but are
relatively silent in others. This location-specific fir-
ing is stable in a fixed environment.
The team assessed rats with four implanted micro-
electrodes for stable single-unit place-field responses.
They compared rats exposed for 30 minutes to a
4 kHz tone at 104 dB sound pressure level (SPL) to
a control period in the same sound chamber. Their
work demonstrated that activation of neural
continued on page 22
14 Tinnitus Today | August 2009
A Walk in the Park and Across America
The First Annual American Tinnitus Association Walk For A Cure
14 Tinnitus Today | April 2009
Setting Up
Saturday, May 16, 2009, Irvine Regional Park, Orange County,
Calif. The perfect day and location for the first annual ATA Walk
For A Cure. At 6:30 a.m., on this beautiful spring morning, volun-
teer event chair Mari Quigley-Miller and several of her Walk com-
mittee members transported tables, chairs and water to the park.
Other event volunteers put up directional signs throughout the
park, clearly marking the way to the designated Walk area. Spirits
were high as more volunteers arrived to set up the registration
area, hang banners and stock the water stations.
Excitement continued to build as event walkers began arriving
around 8 a.m. – many accompanied by their children and ener-
getic dogs on leashes – with great enthusiasm for this unified
effort to support ATA and the fight to cure tinnitus.
Warming up
At 9:00 a.m., Lindy Michaelis, daughter of entertainer Pat Boone,
led the group in stretching exercises. With show business in her
blood, she turned what some consider the mundane part of exer-
cising into something lively and fun.
After the warm-up, Terri Baltus, past ATA chief development offi-
cer, delivered a message on behalf of ATA to an attentive crowd of
around 150 walkers. She thanked everyone for their support and
emphasized that as a group we can accomplish what no one per-
son can do alone. She defined the Walk as the center of a cross-
country, virtual movement that is reaching out into communities
across America.
Terri then introduced ATA-funded research scientist, Fan-Gang
Zen, Ph.D., who was at the Walk with his young daughter, her
friend and a few graduate students from his program at the
University of California, Irvine (UCI). Zeng’s presence was a
“The walk was wonderful.
It was the first walk I’ve
ever been on and it felt so
good to be in allegiance
with everyone there.”
~	Normajean Brady
	 Walk participant & ATA Member
15August 2009 | Tinnitus Today
Thank you to everyone who contributed to the Walk For A Cure.
Thanks to Walk donations by hundreds of supporters, ATA raised $58,379 through the combined
efforts of the walkers in Orange County, the virtual walkers and a direct mailing to our membership.
powerful example of how the money ATA receives from
its members and supporters is helping to fund excellent
research.
Mari then sang a lovely rendition of our National Anthem,
a fitting introduction to a local treasure, Sammy Lee, M.D.
Accomplishing an important dream, Lee received back-to-
back gold medals in diving in the 1948 Olympics in London,
followed by his 1952 triumph at the Helsinki games. He
went on to become a respected ear, nose and throat
(ENT) physician in Orange County. Lee, now retired,
truly understands the problem of tinnitus and supports
ATA’s mission.
A Walk in the Park
Mari, accompanied by her dogs, Sonny and Cher, led
off the mile and a half walk through Irvine Regional Park.
Event organizer Mari Quigley-Miller (second from right) and several
Walk committee members.
Complimentary Walks
At the same time the Orange County
participants were walking in the
park, Donna Brown’s team, “Donna’s
Daytrekkers,” held their own mini-
walk in Denver, Colo. at Van Bibber
Park. Nine team members, including
local tinnitus support group leader Rich Marr, joined
Donna, who climbed Mt. Rainier in support of ATA in
July 2007.
We’d like to hear about anyone else who may have con-
ducted their own mini-walk in support of ATA. Please
send details to Nina Rogozen, Editor, Tinnitus Today,
at nina@ata.org.
Stay tuned this coming winter for details on ATA’s
Second Annual Walk For A Cure, taking place in
Portland, Ore. in the spring of 2010.
15August 2009 | Tinnitus Today
continued on page 16
16 Tinnitus Today | August 2009
The group of spirited, eager walkers ambled along a
peaceful creek, through lush foliage and then circled
back to where the event began. Volunteers handed out
goody bags containing several small, locally donated
items, such as power bars, earplugs and refrigerator
magnets.
After the Walk, people hung
around to enjoy a sense
of camaraderie and the
satisfaction of a mission
fulfilled. Groups clustered
to share conversations with
each other, Zeng, Lee, Mari
and the Walk committee.
One could hear enthusias-
tic Chinese, Spanish and
English voices, a reflection
of the diverse makeup of
the Walk committee and the
walkers they recruited. In addition to conventional local
outlets, tinnitus stories in one Spanish and two Chinese
language newspapers also covered the Walk.
A Walk in the Park and Across America
Many Virtual Walkers Participated
In conjunction with the Orange County Walk, hundreds of
supporters from across America – and a few beyond our
borders – participated in spirit, signing up at the ATA Web
site as fundraising team members and Walk supporters.
We displayed the names of the hundreds of virtual walkers
at the Walk site itself; you can view them by going to
www.ata.org/walk-for-a-cure-list.
continued from page 15
Words About the Walk
Two young men, Jeff Dennison
and Michael Conti, who both
suffer with tinnitus, ran the
entire Walk course. Their
rationale for running at a
walk? “We’re running so we
can get to a cure faster!”
Supporters from Cal National Bank
For the second consecutive year, tinnitus is ranked
as the number-one service-connected disability for
U.S. military personnel returning from the conflicts
in Iraq and Afghanistan. The chart on the left shows the most
common disabilities for returning personnel as of October 2007.
The Incidence of Tinnitus in U.S. Veterans Continues to Escalate
Most common service-connected disabilities for
Iraq & Afghanistan veterans as of October 2007
Iraq & Afghanistan veterans service-connected disability
rates for tinnitus and hearing loss as of October 2008
27%
24%
2007 2008
100,000
90,000
80,000
70,000
60,000
50,000
40,000
30,000
20,000
10,000
0
Information courtesy of VA Office of Public Affairs.
22%
14%
13%
Tinnitus – 27%
Lumbosacral or
Cervical Strain – 24%
Defective Hearing – 22%
Post Traumatic
Stress Disorder (PTSD) – 14%
Limitation in
Flexion of Leg – 13%
TINNITUS
HEARING
LOSS
TINNITUS
HEARING
LOSS
The chart on the right illustrates the sharp increase in service-connected
disability payments to Iraq and Afghanistan veterans for tinnitus from 2007-
2008. The incidence of tinnitus increased more dramatically than did hearing
loss. This is an indicator that other medical conditions, like the demonstrated
link between tinnitus and traumatic brain injury, may be contributing to the
pointed increases in tinnitus among veterans.
17August 2009 | Tinnitus Today
Q:	 How did you decide to participate
in the study?
A:	 I found out through ATA that Dr. Piccirillo was conducting
a new rTMS trial at Washington University in St. Louis.
Because of the promising research reports I have read
about the treatment, I decided that I would explore whether
or not I was a viable candidate. I had an initial consultation
[pre-screening] in September 2008 where the study team
also explained the possible side effects. They told me I was
a good candidate for the study.
ATA Member Participates in Tinnitus Clinical Trial:
A Q&A with Mark W. Church About rTMS
An interview conducted by Daniel Born, ATA Director of Research & Special Projects and
Jennifer DuPriest, ATA Associate Executive Director
Background
Interviewee: March W. Church from
St. Louis, Mo., is a six-year ATA member
and CEO of Application Engineering
Group (AEG), an ATA corporate member.
Mark is 48 years old and has had tinnitus
for 10 years. He describes his bilateral
tinnitus (in both ears) as “wildly fluctuat-
ing tinnitus.”
Topic of study: A two-year, double-blind
study of Repetitive Transcranial Magnetic Stimulation (rTMS),
including 60 participants, led by Jay F. Piccirillo, M.D., F.A.C.S.,
at Washington University in St. Louis, Mo.
Goal of study: To determine if applying rTMS to the hearing area
of the brain can lessen the perception of tinnitus. rTMS involves
placing a strong magnet against a person’s scalp to generate a
small electrical field within the brain. Depending on stimulation
frequency, this electrical field can either decrease or increase
the electrical excitability of the brain. This study uses low-
frequency stimulation since it is thought to decrease nerve
activity. It is this electrical excitability of the brain that is
thought to cause tinnitus.1
Hypothesis of study: rTMS can decrease the perception of
tinnitus. Participants will initially receive either active rTMS
or placebo rTMS for two weeks, then rest for two weeks. Next,
they will receive the treatment they did not receive in the first
two weeks. Treatments will be randomly administered and
participants will not be told which they are receiving. Each
will undergo magnetic resonance imaging (MRI) and positive
emission tomography (PET) scanning of the brain at the
beginning of the study and after each treatment.2
Q:	 Did you undergo any testing before you
started treatment?
A:	 After the initial screening, the study team administered the
Tinnitus Severity Index to determine my specific tinnitus level.
My particular type of tinnitus is pretty bad; it occurs in both
ears and fluctuates wildly. The next day they performed an
MRI and PET scan and mapped my brain activity.
Q:	
What was rTMS treatment like?
A:	 The rTMS device was placed above my left ear and pulsed at
half-second intervals for 20 minutes. There were 10 consecu-
tive treatments, Monday through Friday, with a two-day week-
end break. A two-week rest period took place and then rTMS
was resumed for 10 additional treatments. Memory tests were
administered after every treatment to make sure I was not
having adverse side effects. It was a double-blind study but I
could definitely tell the difference between real treatment and
a placebo treatment. With the real treatment, the left side of
my body jumped like during a knee reflex test.
continued on page 18
What is rTMS?
Repetitive Transcranial Magnetic Stimulation (rTMS) is a pro-
cedure that uses a pulsed magnetic field to influence electrical
activity in the brain. The effects of magnetic fields on humans
were considered as early as the 18th century by Franz Anton
Mesmer, a German physician and astrologist. However, it was
not until the end of the 19th century that scientists started
using magnetic energy to alter brain activity.3
Interview with Mark Church
18 Tinnitus Today | August 2009
Over the past two years, ATA has enjoyed
some major advocacy accomplishments. The
Department of Defense (DoD) now supports
tinnitus research through its Peer Reviewed
Medical Research Program (PRMRP) for the
first time since the program’s inception.There
is now successful inclusion of directive com-
mittee report language that has accompanied
the Labor Health and Human Services bill for
the past three years. This language encourages
the National Institutes of Health (NIH), the
DoD and the Department of Veterans Affairs
(VA) to come together to collaboratively
address tinnitus from a multi-disciplinary
approach. The result is a tinnitus-specific
workshop hosted by the National Institute on
Deafness and other Communication Disorders
(NIDCD) regarding “Brain Stimulation for the
Treatment of Tinnitus,” being held Aug. 13-14,
2009 on the NIH Campus. And lastly, the
establishment of a DoD Center of Excellence on
auditory systems injury for our military and
veterans, who experience tinnitus dispropor-
tionate in numbers, and often in severity, to
the rest of the population.
We are Grateful for Congressional Support
ATA and the rest of the tinnitus community owe a
debt of gratitude to the elected officials who helped
make these initiatives become reality. Because of
their work, ATA chose to honor two outstanding
Senators whose leadership and support of ATA’s
mission to cure tinnitus made these accomplish-
ments possible.
Q:	 What sorts of safety precautions
were in place?
A:	 The team did a hearing test [audiogram] at three different intervals
to ensure no damage to my hearing center was taking place. There
were constant questionnaires and memory tests, plus three psycho-
logical exams to test for possible cognitive changes.
Q:	 Did you have any concerns about
the process?
A:	 The MRI machine was very loud and physically uncomfortable. It is
difficult to lie still for such a long period of time. I had to mentally
psyche myself into getting through it as I am somewhat claustro-
phobic. It was also time consuming; I spent two hours each day
having rTMS treatment. Then I had six hours of PET and MRI scans
and other tests.
Q:	
Did you experience any side effects?
A:	 Besides my left side jumping uncontrollably during the treatment,
no. I was told that some people experience headaches, but I felt fine.
Q:	
Did the treatment work?
A:	 rTMS was not effective for me - but I want to do my part and help
get us closer to a tinnitus cure.
Q:	 Would you participate in another
tinnitus treatment study?
A:	 Dr. Piccirillo is a class act, and his team was very professional. I
am open to taking part in other aspects of his tinnitus treatment
research. In fact, he has a second part of the rTMS study that I will
be participating in and will let you know how it goes.
A Q&A with Mark W. Church About rTMS
continued from page 17
1
http://clinicaltrials.gov/ct2/show/NCT00567892?term=tinnitus&rank=19.
2
Ibid.
3
http://www.bnl.gov/medical/tms/history.asp.
18 Tinnitus Today | August 2009
It was a double-blind study but I could definitely tell
the difference between the real treatment and a pla-
cebo treatment. With the real treatment, the left side
of my body jumped like during a knee reflex test.
rTMS was not effective for me – but I want to do
my part and help get us closer to a cure.
~ Mark Church
Honoring New
Friends in Our
Nation’s Capital
By Jennifer DuPriest,
ATA Associate Executive Director
19August 2009 | Tinnitus Today
On May 12-13, 2009, Scott C. Mitchell, J.D., recent past
chair, ATA Board of Directors, board members John
Bates and Michael O’Rourke, ATA government relations
counsel Deborah Outlaw and I visited the offices of
Senator John Cornyn (R-TX) and Senator Harry Reid
(D-NV) to thank them personally for their support
and to honor them for their essential actions toward
curing tinnitus.
Senator Cornyn has always been deeply committed to
serving America’s veterans. Because of ATA’s education
of the Senator and his staff about the growing incidence
Conversations with a Senator: Scott C. Mitchell,
J.D., John R. Bates, Jennifer DuPriest and Senator
John Cornyn (R-TX) in his Washington, D.C. office.
A T A A D V O C A C Y I N A C T I O N
of tinnitus in active duty military and veterans, he
supported the creation of the DoD Center of Excellence
on auditory systems injury, included in the final 2009
DoD Authorization Bill. This center will not only pro-
vide critical care to members of the military who suffer
with tinnitus, but will provide educational materials
and conduct ongoing research on its patient popula-
tion. These efforts will help continue to inform the
tinnitus research community about a certain kind
of tinnitus and help us all get closer to our collective
goal of silence.
Senator Reid is also deeply committed to serving
America’s veterans and understands the importance
of funding biomedical research for all who suffer from
this condition. Again, ATA’s education of congressional
members about this often overlooked condition resulted
in Senator Reid’s gracious support of the inclusion of
tinnitus as a researchable condition in the PRMRP.
We look forward to continued work with both Senators
Reid and Cornyn and all the other members of Congress
who are helping ATA pave the way to a cure!
19August 2009 | Tinnitus Today
20 Tinnitus Today | August 2009
In this ATA-funded study,
we examined the properties
of DCN neurons seven days
after intense sound exposure
and compared them to normal
neurons. Families of special-
ized proteins called “ion chan-
nels” are located in neuronal
membranes and selectively
allow ions (charged atoms,
such as sodium, potassium
and chloride) to move in or
out of the cell. This movement
depends on the voltage across
the neuron’s membrane and
the difference in the concen-
tration of ions between inside
and outside the cell. Opening
ion channels changes the voltage across the cells’
membranes. Opening and closing of specific types
of ion channels produces action potentials (Fig. 1),
which are the means by which neurons send infor-
mation to other neurons. Other ion channels control
the pattern or time between action potentials.
We have found a marked change in membrane
properties in DCN neurons following intense sound
exposure. The changes are consistent with an over-
all increase in the opening of ion channels at rest.
In addition, after intense sound
exposure, there is an increase in
DCN neurons firing two action
potentials (couplets) in rapid suc-
cession. We also observed this
firing pattern in our recent study,
using recordings from outside
cells; we directly observed the
underlying membrane potential
changes associated with firing
in couplets.
Future Work
Future characterizations of the
ion channel changes produc-
ing these membrane potential
changes, and the increase in open
channels (measured as increased
conductivity) following intense
sound exposure, may demonstrate
changes that are important in the
generation of tinnitus. Changes
in ion channels have also been
found to be important in the
change in neuronal activity asso-
ciated with phantom pain, a con-
dition similar to tinnitus. Studies
on phantom pain provide impor-
tant examples of changes that
should be examined in tinnitus.
In conclusion, this study provides the groundwork for
identifying and understanding specific ion channels,
which may be altered in tinnitus. This information
could lead to targeted treatments for tinnitus.
Paul G. Finlayson, Ph.D., is Assistant Professor of
Otolaryngology and Ophthalmology for the Wayne
State University School of Medicine in Detroit, Mich.
He was recently named interim scientific director of
the Ligon Research Center of Vision at Kresge Eye
Institute, also in Detroit.
Tinnitus and Hyperactivity in Dorsal Cochlear Nucleus Fusiform
Cells: What Biophysical Changes Occur in These Cells
Paul G. Finlayson, Ph.D., Wayne State University, Detroit, Mich.
An effective tinnitus treatment may depend on our understanding of the alterations in the brain and
in the cells/neurons which produce these phantom sound sensations. Animal models have shown that
intense sound exposure increases spontaneous “firing activity” (action potentials) in neurons, such
as in one of the first brain auditory centers, the dorsal cochlear nucleus (DCN). Action potentials are
the major way neurons communicate information, such as sound, and an increase in their rate could
produce the phantom sounds of tinnitus.
Figure 1. Dorsal Cochlear Nucleus
cells were more likely to produce action
potentials in couplets. This rapid pattern
of activity is more likely to be perceived
as sound by other areas of the brain.
(“milli” = 1/one thousand; 1/1000).
Paul G. Finlayson, Ph.D.
21August 2009 | Tinnitus Today
Medical treatments for tinnitus have historically
been difficult to evaluate. This is due to the
extremely complex nature of tinnitus, diversity of
tinnitus causes and lack of understanding about
underlying mechanisms. Limited measurement tools
and the challenges in the lives of those who suffer
from tinnitus contribute to evaluation difficulties.
The American Tinnitus Association is co-funding
a clinical trial of a medication called acamprosate
(brand name, Campral®) at the Oregon Health
& Science University (OHSU) in Portland, Ore.
Acamprosate was developed to help recovering
alcoholics abstain from drinking by modifying the
balance between excitatory (when nerves activate
other nerves) and inhibitory (when nerves prevent
others from activating) chemicals produced by the
brain. It is possible that an imbalance in the hearing
centers of the brain (not related to alcoholism) may
be one cause of tinnitus. A pilot study in Brazil
suggested that acamprosate might be helpful for
some types of tinnitus.1
Bringing Participants on Board
The three-year OHSU study began in January 2008
and has been a massive endeavor. So far we have
processed over 2,000 contacts from tinnitus suffer-
ers interested in being in the study. Of those, 596
individuals went through screening evaluations and
234 have met the very strict inclusion criteria to par-
ticipate in the study. Most of those have enrolled in
Phase I of the trial.
Phases I, II and III
Phase I is an open-label trial (both the researchers
and participants know the identity of the treatment)
during which all participants take acamprosate for
six weeks. Those who respond positively to the
medication may continue into an extended Phase II
of the study. We release from the study those who
did not have a positive response to the acamprosate
in Phase I or asked to be released for other reasons,
such as side effects, logistics or time constraints.
During this second phase, everyone receives acam-
prosate for part of the time and a placebo for part
of the time, without knowing which they are taking
at any given time. This experimental design is very
important because it recognizes that no treatment
should be expected to work for everyone with tinni-
tus. It separates non-responders from potential true
responders early in the study and allows us to focus
resources and research efforts on those most likely
Clinical Trial of Acamprosate for Tinnitus
William Hal Martin, Ph.D., and Yong-Bing Shi, M.D., Ph.D.,
Oregon Hearing Research Center, Oregon Health & Science University
to benefit from the
treatment.
We are continuing
to enroll participants
in Phase I and hope
to enroll about 300
people in all. We
have begun Phase
II as well. During
Phase III of the
study, we will look
back at those who
did and did not
respond positively
to acamprosate.
(This can include a
decrease in the per-
ceived loudness of
their tinnitus, or an
improvement in their
overall quality of life.) During this review process,
we identify factors (tinnitus pitch, loudness, duration,
other medical issues, etc.) about those groups that will
help us predict who should or should not benefit from
acamprosate treatment. We believe that this will help
us understand the role of the brain in tinnitus and help
us develop more effective treatments in the future.
Recognition for Innovative Design
The tinnitus research community recognizes this
study for its importance on three levels. First, every-
one is interested in knowing if medications like
acamprosate can be helpful to those with tinnitus.
Second, we are all interested in the role of the brain
in tinnitus and this experiment allows us to change
brain chemistry in a very interesting way. Finally, and
perhaps most importantly, this is the first time anyone
has applied this type of strict experimental design to
studying interventions for tinnitus. The design may
prove to be the standard by which the research com-
munity evaluates all future medical therapies.
William Hal Martin, Ph.D., is Professor of
Otolaryngology/Head and Neck Surgery and Professor
of Public Health & Preventive Medicine at the Oregon
Health & Science University in Portland, Ore. He
directs four programs within the Oregon Hearing
Research Center: the OHSU Tinnitus Clinic, Tinnitus
Research Program, Intraoperative Neurophysiological
Monitoring Services and Dangerous Decibels® Noise
Jennifer Petersen, Au.D., OHSU Senior
Tinnitus Specialist, Yong-Bing Shi, M.D.,
Ph.D., and William H. Martin, Ph.D.
continued on page 25
22 Tinnitus Today | August 2009
plasticity through overstimulation of sound can alter
the response of these hippocampus place cells.
Tinnitus in Young Patients Up to 35 Years Old6
Poland, 2008
Tinnitus can occur even in the young. According to
the work of Danuta Raj-Koziak, M.D., and her team
in Poland, it is becoming more common in young
people. They found that about 25% of patients
registered in their tinnitus clinic are below the
age of 35. Their study evaluated a group of 235
tinnitus patients ranging in age from 18 to 35 years
old. There were no other pre-selection criteria
except age. All participants answered questions
concerning the cause of their tinnitus. Their findings
indicate that the most frequent tinnitus triggers
among patients below 35 years are infections
(68.5%), noise exposure (27.7%) and stress (23.4%).
Tinnitus Treatment: Neurosurgical Management7
France, March 2009
Tinnitus management requires a multidisciplinary
approach in which neuromodulation and neurosur-
gery tend to play major roles. One classification of
tinnitus is objective tinnitus (sounds in the ear that
can be heard by someone besides the person with
tinnitus). One form is pulsatile tinnitus, synchronous
with one’s heartbeat. Radiological testing should
search for a vascular abnormality as well as other
neurological diseases (intracranial hypertension,
Arnold-Chiari malformation, vascular loops, etc.).
Asynchronous objective tinnitus generally corre-
sponds to muscular contractions requiring specific
management.
The other classification
is subjective tinnitus
(perceived only by
the patient), which
is more complex
and strongly
analogous with
post-amputation
pain syndromes.
After peripheral
middle ear or
inner ear damage,
auditory deafferen-
tation (freeing of sen-
sory nerve fibers) could
result in hyperactivity and/
or functional reorganization within central auditory
and nonauditory structures of the brain. According
to Alain Londero, M.D., and his colleagues, this
could explain the persistence of tinnitus after sever-
ing the 8th auditory nerve, and associated symptoms
such as hyperacusis or anxiety and depression. This
model finds strong support in animal experiments
and in functional neuroimagery (PET, fMRI, MEG).
Without etiologically-based therapies available,
severe, subjective tinnitus management only targets
tinnitus tolerance with sound enrichment or cognitive
behavior therapy. Soon, better knowledge of tinnitus
pathophysiology and innovative therapeutic tools
could emerge from neuromodulation techniques,
such as repeated transcranial magnetic or epidural
electric stimulation.
Educational Counseling Used in Progressive
Audiologic Tinnitus Management8
United States, January-March, 2009
Exposure to loud sounds commonly causes or
exacerbates tinnitus. The National Center for
Rehabilitative Auditory Research conducted clinical
research, led by James A. Henry, Ph.D., which
resulted in a clinical model of tinnitus management:
Progressive Audiologic Tinnitus Management
(PATM). It involves five levels of management:
triage, audiologic evaluation, group education,
tinnitus evaluation and individualized management.
A key part of PATM is counseling by audiologists
and, as needed, mental health providers. Rather
than focusing on didactic, informational counseling,
it facilitates patients’ learning to better adjust to the
disturbing auditory realities of tinnitus. It employs
tools from two powerful skills sets advantageous
to the self-management of chronic tinnitus: the
use of therapeutic sound and cognitive-behavioral
psychology techniques.
	
1
Cacace A. Tinnitus Research: Tales From a Grand Meeting at Grand Island, N.Y, Am J
Audiol. 2008 Dec;17(2):107.
2
Tyler R, Coelho C, Tao P, Ji H, Noble W, Gehringer A, Gogel S. Identifying tinnitus sub-
groups with cluster analysis, Am J Audiol. 2008 Dec;17(2):S176-84.
3
Khedr EM, Rothwell JC, Ahmed MA, El-Atar A. Effect of daily repetitive transcranial
magnetic stimulation for treatment of tinnitus: comparison of different stimulus frequen-
cies. JNNP. 2008;79:212-215.
4
Argstatter H, Crick C, Belay HV. Music therapy in chronic tonal tinnitus. Heidelberg
model of evidence-based music therapy. HNO. 2008;56:678-685.
5
Goble TJ, Møller AR, Thompson LT. Acute high-intensity sound exposure alters responses
of place cells in Hippocampus. Hear Res. 2009 Mar 18. [Epub ahead of print]).
continued from page 13
Highlights: Selected 2008-2009 Tinnitus
23August 2009 | Tinnitus Today
The following definitions will assist you in reading “Highlights:
Selected Tinnitus Research Studies in 2008-2009” (beginning on
page 12), which describes some of the notable tinnitus research
results from around the world.
Audiogram: a graphic representation of the relation of vibration
frequency that shows the softest sounds a person can hear at
different pitches or frequencies.
Auditory deafferentation: elimination or interruption of sensory
nerve impulses by destroying or injuring the sensory nerve fibers.
Basal measures: measurements of vital organism activities,
such as heartbeat and respiration.
Bilateral tinnitus: affecting both the right and left ears.
Cross-sectional survey: a study in which a statistically signifi-
cant sample of a population is used to estimate the relationship
between the results of the study and the various characteristics
of the population studied at a certain point in time.
Dorsal Cochlear Nucleus (DCN): a cortex-like structure on the
dorso-lateral surface of the brainstem where auditory nerve fibers
from the ear’s cochlea form their first synapses.
Epidural region: the outermost part of the spinal canal.
Epidural electric stimulation: treatment involving implanted
electrodes in the epidural region of the body.
Etiology: the cause or causes of a disease or abnormal condition;
a branch of medical science dealing with the causes and origins
of diseases.
Hippocampus: an area deep in the forebrain that helps regulate
emotion and memory.
Hippocampal pyramidal neurons: multipolar sensory neurons
located in the hippocampus region of the brain.
Hyperacusis: over-sensitivity to some frequency ranges of sound.
Intracranial hypertension: a condition where the cerebrospinal
fluid (CSF) inside the skull reaches elevated levels.
Multidisciplinary approach: composed of or combining several
usually separate branches of learning or fields of expertise,
specialized subjects or skills.
Neuroauditive cortex: the region of the brain responsible for
processing auditory (sound) information.
Neuroauditive cortex reprogramming: a therapy utilizing sound
to reduce the perception of tinnitus.
Neural plasticity: the ability of neural circuits to undergo changes
in function or organization.
Neuroimagery: various techniques (PET, fMRI and MEG) used to either
directly or indirectly image the structure and function of the brain.
Neurons: excitable cells in the nervous system that process and
transmit information by electrochemical signaling.
Objective tinnitus: head or ear noises audible to other people as
well as the patient.
Occipital: of, relating to or located within or near the occiput
(back of the head) or the occipital bone.
Psychoacoustics: a branch of science dealing with subjective
human perceptions of sounds.
Sham: a treatment, e.g., medication or procedure, used in a scientific
study as a control, usually omitting some or all key therapeutic ele-
ments of the treatment being studied; commonly called a “placebo.”
Somatic modulation: movement of the jaw, head or neck that causes
the loudness and/or frequency of one’s tinnitus to fluctuate.
Somatosensory: of, relating to, or being sensory activity with an
origin elsewhere than in the special sense organs, e.g., eyes and
ears, and conveying information about the state of the body proper
and its immediate exterior environment.
Subjective tinnitus: head or ear noises audible only to the sufferer.
Synaptic plasticity: the ability of the synapse (connection) between
two neurons to change in strength.
Temporoparietal cortex: a region of the brain known to be involved
in speech perception.
Tinnitus Handicap Inventory: a self-reported test utilized to assess a
person’s tinnitus-related handicap and to report treatment outcomes.
Tonal tinnitus: a continuous sound with a well-defined frequency;
heard as ringing, buzzing, chirping.
Vestibulocochlear nerve: a sensory nerve responsible for transmit-
ting sound and equilibrium information from the inner ear to the
brain; also known as the 8th nerve.
Tinnitus pathophysiology: the study of the changes of normal
mechanical, physical and biochemical functions affected by tinnitus.
Research Studies
6
Raj-Koziak D, Bartnik G, Skarzynski H, Pilka A, Fabijanska A, Borawska B., Tinnitus in
young patients up to 35 years old. Otolaryngologia Polska. 2008;62:476-479.
7
Londero A, Chays A. Tinnitus treatment: neurosurgical management. Neurochirurgie
2009 Apr;55(2):248-258. Epub 2009 Mar 20.
8
Henry JA, Zaugg TL, Myers PJ, Kendall CJ, Turbin MB. Principles and application of edu-
cational counseling used in progressive audiologic tinnitus management. Noise Health.
2009 Jan-Mar;11(42):33-48.
Glossary of Research Terms
24 Tinnitus Today | August 2009
Questions and Answers
Notice: Please feel free to call Dr. Vernon any Friday, 9 a.m. to noon and 1 to 5 p.m. Pacific Time at
(503) 494-2187 (please do not leave messages). You can also e-mail your questions to Nina Rogozen,
Editor, at nina@ata.org or mail them to Tinnitus Today, American Tinnitus Association, P.O. Box 5,
Portland, OR 97207-0005.
Jack A.Vernon, Ph.D.
QMy tinnitus (mild nonstop ringing in both ears)
started in 1990 and was caused by extreme stress
and worry when I received some very bad news. My
theory is that this stress released chemicals in my
body, including in my brain. I would like to know
if stress has caused tinnitus for any other readers.
A Stress causes the human body to release stress
hormones, which stimulate its ability to escape
or conquer the stressful situation. They target specific
organs of the body and generally have an immediate
effect. Many parts of the body can be affected by stress.
The heart and cardio-vascular system are good exam-
ples of places adversely affected by stress, such as heart
attacks and high blood pressure. Individuals vary con-
siderably in their psychological reactions to stress, which
also depend on the origin of the stress and their ability
to handle it. But one thing is pretty certain: all stress –
physical, psychological, emotional or spiritual – results
in physiological responses. It is difficult to say whether
the stress was the primary cause of your tinnitus.
QI sometimes experience a ticking sound in
my right ear. Recently when this happened,
I simultaneously felt tightness and pulsing in the
area from the underside of my chin toward my neck
(right side). It was more noticeable when I was lying
on my back. It lasted for a few weeks and is now
gone. Have you ever heard of this and is it possible
that there is a muscle, tendon or ligament that is
pulsing with the ticking?
Regarding your temporary ticking sounds, these and
similar types of mechanically-originating sounds are
not uncommon. And tinnitus is often accompanied by
a sensation of pressure. Sometimes a Eustachian tube
dysfunction appears to cause the problem. Also, we
now know that tinnitus in some people may change
when they move their jaw or neck or press on the mus-
cles of the head. Those clicking sounds that you heard,
and the sensation of pressure, may have been caused
by spastic behavior of the complex muscles of the head
or neck. It is possible that they are indicative of some
temporary abnormality of your temporomandibular
joint on one side. If you experience such feelings again,
you may be clenching your teeth, tightening your jaw
or grinding your teeth while sleeping. If it becomes too
QI am an ATA member and here is my ques-
tion. In the history of medicine, has there
ever been a case where tinnitus has stopped, gone
away and left the victim alone? If so, I figure that
there is still hope; and since it happened to someone
else, it could happen to me. If not, I will continue to
live with it and hope they find a cure during my
lifetime. That’s my question du jour. Thanks for
your help.
AYes, tinnitus can disappear on its own, but
this is rare and we don’t know the conditions
that cause it to do so. Sometimes the disappearance
seemed to be related to the use of masking. Other
times it just spontaneously went away, however that
is very uncommon.
You don’t have to wait around hoping for a sponta-
neous disappearance. There are things you can do
to help yourself, such as masking – using a variety
of sounds to block the tinnitus, such as ambient
noise, TV or radio, fountains. Some people find
relief with Xanax® (alprazolam, an anti-anxiety
drug) and some utilize methods of counseling
that help them better manage their tinnitus.
25August 2009 | Tinnitus Today
annoying, your dentist could refer you to someone
who can provide you with a temporary “fix” – a
plastic insert to wear in your mouth at night that
prevents teeth grinding.
QI hear a lot of comments about a cure for
tinnitus but I do not hear any comments
as to how such a cure might be found. In your
opinion, is a cure a realistic possibility, and if so,
how will it come about?
A Yes, I think a cure is possible, at least for
certain kinds of tinnitus. As you well know,
as hearing declines, tinnitus increases; it’s something
of a see-saw effect. Now given that dynamic, if we
can improve hearing it is my guess that tinnitus
will decrease.
How do we increase hearing? Hopefully we’ll do it
with stem cells. We can harvest these versatile cells
from the person’s own nasopharynx (uppermost part
of the pharynx, extending from the base of the skull
to the upper surface of the soft palate) so that there
is no or little chance for rejection. In my opinion,
work with stem cells has the possibility of enhancing
recovery from all manner of health problems.
“Visiting your Houston clinic was
the best thing I ever did.” – Lupe G.
“You gave me my life back.” – Allan W.
Migraine-Meniere-Tinnitus Clinic
We identify and treat the causes and triggers of tinnitus
Soraya Hoover, M.D., Medical Director
At the Migraine-Meniere-Tinnitus Clinic, we focus our diagnosis & treatment on
the patient’s physiological, pathological and anatomical malfunctions of their
nose, sinuses and Eustachian tubes. Treatment corrections aim to normalize
functions and equalize the nasal airway. This may take three to 10 days.
We accept most Medical insurance plans. Please call for more information.
Dr. Hoover is a Fellow of the American Academy of Otolaryngology, Board of Allergy
& Environmental Medicine and Royal Society of Medicine, London, and a Diplomat
of the Royal College of Surgeons of England. Dr. Hoover has served the Houston
area for 25 years, spoken in over 26 countries and published in numerous medical
journals, such as:
–	International Rhinology. Supplement 2.all.1987
–	Tinnitus & Allergy. Proc II International Tinnitus Seminar, Munster, Germany.
1987. Publisher, Harch V. Karlstruhe
–	The Journal of Japan Rhinologic Society. Vol 30,1(1991)
Shepherd Exit – 5151 Katy Freeway, Suite 300, Houston, TX 77002
Call (713) 626-4999 to make an appointment
www.tinnitus-menieresclinic.com/index.htm
http://www.headache-migraineclinic.com
ATA does not endorse or recommend any tinnitus products or treatments.
Advertisement
delicate cilia (ear hair cells) leading to SNHL,
tinnitus and hyperacusis.
Treatment for REKS has not yet been successful,
but prevention is a must. A light kiss to a child’s ear
produces a surprisingly rapid and intense ear canal
vacuum.5
An infant cannot say, “Mommy, I can’t hear
now.” Let us avoid preventable tragedies like this.
Kiss, and kiss away, but please avoid that ear canal.
Dr. Levi A. Reiter is Professor of Audiology and the
audiology program head at Hofstra University’s
Department of Speech-Language-Hearing Sciences.
He teaches courses in diagnostic audiology, anato-
my and physiology, psychoacoustics, deafness and
electrophysiology. He is also on the faculty of the
Long Island Audiology Consortium and maintains
an active audiology practice in Brooklyn, N.Y. The
grandfather of 20 is a published rapper and enjoys
promoting the audiology profession with songs
like, “Say Whut?”
1
Reiter, L.A. The kiss of deaf. The Hearing Journal. 2008
Aug;61(8):32-37.
2
Reiter, L.A. Pathologic sequelae of ear-kissing. Abstracts of
the Meeting of the Association for Research in Otolaryngology.
2009 Feb;604.
3
Reiter, 2008.
4
Smaka, C. The kiss that caused hearing loss, or Reiter’s
Ear-Kiss Syndrome (REKS). Audiologyonline. 2008 July 28.
5
Reiter, 2009.
Can a Simple Kiss on the Ear
Cause Auditory Problems?
continued from page 11
Clinical Trial of Acamprosate
for Tinnitus
continued from page 21
Induced Hearing Loss and Tinnitus Prevention
Program. Martin also serves as the Research
Scientist in Residence at the Oregon Museum
of Science and Industry (OMSI) in Portland.
Yong-Bing Shi, M.D., Ph.D., is Assistant Professor of
Otolaryngology/Head and Neck Surgery at the Oregon
Health & Science University. He examines and treats
patients with tinnitus and hearing problems, as well
as voice and swallowing disorders. He also serves as
the medical director of the OHSU Tinnitus Clinic and
the Northwest Center for Voice and Swallowing.
In addition, Shi monitors brain, nerve and spinal
cord function during surgical procedures in which
those structures may be injured by the procedure.
1
http://www.ncbi.nlm.nih.gov/pubmed/15000513.
26 Tinnitus Today | August 2009
Corporate Champions
$5,000+
AEG is a comprehensive
business solution company
that provides information
technology (IT) services to
companies and organiza-
tions throughout the U.S.  
Leadership Donors
$100,000+
Marianna Dennis
Sustaining Donors
$1,000 to 4,999
Anonymous (2)
Dennis W. Anderson
Bryan Richard Aubie
Sandra E. Baan
Joseph F. and Frances A. Bachman, M.D.
John R. Bates
Anthony T. Cacace, Ph.D.
Stephen and Jennifer Sue Chandler
of the Scottsdale Foundation
Neil Cherian, M.D.
Roland D. DeCastro
Jeffrey A. Ferenz
Foreningen Lydhoer
Ronald K. and Donna Mae Granger
Richard E. Haney, Ph.D.
John Horst, Famous Tate Electric Company
Jim and Angela Hsu
William H. Hurt
Mrs. Leonard E. Johns
Mark K. Johnson, J.D.
Arthur F. Kuckes and Martha A. Wright Fund
of the Tompkins Charitable Gift Fund
John Malcolm
Robert B. Maloney
Bruce F. Martin
Steve Martin Charitable Foundation
Mary B. Meikle, Ph.D.
Microsoft
Gary P. Reul, Ed.D.
Stephen M. Schwarcz, D.D.S.
and Wendy J. McPherson
Jerry Shannon
Jack A. Vernon Ph.D. and
Mary B. Meikle, Ph.D.
John L. Zabriskie and
Adelaide W. Zabriskie Fund
Special Donors and Tributes
Thank you to all of our donors. Your generosity and commitment make possible
ATA’s continuing effort to support innovative tinnitus research – investigations that
are searching for improved tinnitus treatments, and eventually a cure.We greatly
appreciate each and every ATA member.Without you, there would not be an
American Tinnitus Association.
We’d like to provide you with even more information on tinnitus on the pages
of Tinnitus Today. Therefore, beginning with this issue, Supporting Donors
($100-499) will now be displayed on ATA’s Web site and can be viewed at
www.ata.org/get-involved/donor-recognition.We will be recognizing all $100+ donors
in the April issues of Tinnitus Today for the previous calendar year.
All contributions to the American Tinnitus Association are tax-deductible to the
extent provided by law. For more information about giving to ATA, please contact
Katie Fuller at (800) 634-8978 x220 or katie@ata.org.
The gifts listed below include those from January 1, 2009 through June 30, 2009.
Distinctive groups of individuals and organizations
ATA is proud to have the following individuals and organizations support our research
efforts and our crucial involvement in the tinnitus community.They include members
of the Jack Vernon Legacy Society, those who have generously included ATA in their
planned giving; our Corporate Membership Program; and Professional Membership
Program. The lists below include memberships through June 30, 2009.
Corporate Membership Program
Anonymous (1)
Virginia Blackman
John U. Buchman, M.D.
Carl L. Cochrane
Simon Couvier
Jules H. Drucker
Joy A. Fogarty
Drs. Norman and Gilda Greenberg
D. G. Gumpertz
Marcene M. Herron
Ginger L. Hoiland
Ben L. Jones
Harold M. Kahn, Jr.
Cliff Kohler
Virginia L. Lipp
Marita Maxey
Mary B. Meikle, Ph.D.
Ruth E. Ochs
Edward P. Rosenberg
James W. Soudriette
Neil Valentino
Delmer D. and Wanda Weisz
Jack Vernon Legacy Society
ATA offers a special thanks to our Founding
Members, (names bolded below) who
joined by June 30, 2008, and helped ATA
successfully launch this great program.
As of June 30, 2009, our Professional
Membership Program includes:
Research Champions
Dhyan Cassie, Au.D., F/AAA
Ali A. Danesh, Ph.D.
Mary B. Meikle, Ph.D.
Stephen P. Ratner, BC-HIS
Michael J. A. Robb, M.D.
Paula Schwartz, Au.D.
Professional Members
Dassan Ali, Sc.D., CCC-A
Marcia L. Anderson, Au.D., FAAA
Marty Ann Apa Au.D.
Janie P. Barnett, Au.D.
Kathleen Bartels, CCC-A/SLP
Randall Bartlett, M.A.
Linda Beach
Denise Bickley, M.A., Au.D.
Gail B. Brenner, Au.D., CCC-A
Frank Cardarelli
Max S. Chartrand, Ph.D.
Alissa Claar, Au.D.
Laurie Drake, Au.D.
Professional Membership Program
Timothy L. Drake, BC-HIS
Michel Eybalin, Ph.D.
Melodi B. Fehl, Au.D.
Flash Gordon, M.D.
Mark Gulliver MSc, Au.D.(C)
James A. Henry, Ph.D.
Sharon T. Hepfner, MA, FAAA
Melanie Herzfeld, Au.D.
Michael L. Hill, Au.D.
Maria Holdren, M.S.
Soraya Hoover, M.D., P.A.
Jacquelyn C. Jackson, Au.D.
Victor Jovan, BC-HIS
Tae Yoo Kim
Gregory D. King, Au.D., CCC-A
Martin H. Kulick, D.M.D.
John Kveton, M.D.
Deborah R. Lain, B.A., MSc.
Gail H. Leslie, Au.D.
Malvina C. Levy, Au.D.
Paula Liebeskind, M.S., CCC-A
Joyce Lim
Thomas J. Lobl, Ph.D.
Michael Mallahan, Au.D.
Randa Mansour-Shousher, Au.D.
Maura G. Marks, Ph.D., Au.D, CCC-A/SLP
Sara Mattson, Au.D.
David L. Mehlum, M.D.
Jill B. Meltzer, Au.D.
Karen Mercer, M.A., FAAA
Carl M. Nechtman, M.D., P.C.
Alfred L. Nuttall, Ph.D.
Phil Pack, M.S.
Meredith K. L. Pang, M.D.
Debbie Papadakis, M.Ht., BCH, C.I.
Treva Paparella
Margaret F. Peak, Ph.D.
Stephen R. Plumlee
Jean-Luc Puel, Ph.D.
Donald E. Regan, Ph.D.
Burke Richmond
Terry L. Roberts, Au.D.
Allen W. Rohe, Au.D., FAAA
Sharon Rophie, Au.D.
Roger A. Ruth, Ph.D.
Gabrielle Sadowsky, CCC-A
Katharine Sorenson, Au.D.
Edward Szumowski, Au.D.
Deborah L. Taylor, BC-HIS
Wayne Tipps, D.D.S.
University of Buffalo, Speech-Language &
Hearing Clinic
Erin Walborn, Au.D.
Kim S. Worona, M.S.N., RN
Contributing Donors
$500-999
Patricia M. Atwood
Arvest Bank
Rod Barron
Roberta M. Bartik
Gary A. Bleiberg
Marcia Powell Chapman, MSW
James O. Chinnis Jr., Ph.D.
Clear Products, Inc.
Anthony G. A. Correa
Frederick R. Entwistle, M.D.
Flexion Therapeutics, Inc.
Mark L. Goldberg
John R. Grayson Fund
Hearing Loss Association of
America
David Michael Keeter
Jodi Klein
Richard and Eva Klein
Robert K. Mauer
Michael J. A. Robb, M.D.
Thomas Sylvest
Tom J. Walen
Delmer D. and Wanda Weisz
Patricia H. Westheimer
Raymond V. Wojtusiak
J. Richard Yourtee
TRIBUTES
IN MEMORY OF:
Grant Acker
	 Henry Tobin, Ph.D.
Nancy Anderson
	 John and Faye Schleter
Pamela Armstrong
	 Adella Bratsos
Terry Asbury
	 Jack Asbury
Bear
	 Marco T. Carpio, M.D. and 	
	 Linda E. Carpio, LCSW
26 Tinnitus Today | August 2009
Joyce A. Berger
	 L. Ralph Berger
Sandra Bloom
	 John J. and Ann F. Henry
Robert Branigan
	 August E. Firgau
Curtis H. Carlson
	 Stephen C. Carlson
Bert Cooper
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Theodore J.G. Cotter
	 C.M Gucwa
Joseph DeAngelo
	 Rose DeAngelo
Charles Goldstein
	 Diane Schwab
Edward Goodman
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Trudy Gottfried
	 Barsh Hearing Aid Center
John Greve
	 Catherine Greve
Dorothy Guttenberg
	 Stuart J. and Marcy L. Feldman
Herbert Hand
	 Donna Cronister
	 Naena Grissett
	 Nancy Huffman
	 Florence Mugnolo
	 Monte Nienkerk
	 Dr. and Mrs. Ron Rainosek
	 Steve Werner
Leonard E. Johns
	 Mrs. Leonard E. Johns
James Ihasz
	 Michael Bellizzi
Bob Johnson
	 Wayne Olsen
Edward J. Keels
	 Edward W. Keels
Margie Keeter
	 David Michael Keeter
Stephen Klincik
	 Karen K. Adams
Nellie Koslosky
	 Richard Koslosky
Lettie Mannaway
	 Alexander M. and Doris Friedman
Ruby L. Masters
	 Abbas Emami, M.D.
David Loew
	 Lisa Wilson
James McLeod
	 Michael Dorosh
Irene Nelson
	 Marco T. Carpio, M.D.
	 and Linda E. Carpio, LCSW
Karol C. Neiderfringer
	 Alan Niederfinger
	 Pennrose and Sallyann R. Wolf
Alan Nickerson
	 Stephen and Deborah Cohen
Raymond Pantano
	 Greg and Jacquie Amiriantz
	 Linda Beach
	 William A. Fiordimondo
	 Ellen Pantano
William Patterson
	 Shreve High School Class of 1951
Leonore Mary Petito
	 Rosemary C. Petito
Steve Rodgers
	 Scott A. Wilhelm
Jonathan Rushing
	 David N. and Mary Edna Rushing
Elizabeth V. Saunders
	 James C. Saunders, Ph.D.
George Sciarrotta, Sr.
	 Thomas Sciarrotta
Theresa Senner
	 Janice Kirkland
Wanda Mae Shannon
	 Jerry Shannon
Merchant D. Slocum
	 Elizabeth Holden
Gert and Harold Soll
	 Paul Soll
Dana Lynn Spath
	 Patricia Spath
Charles Tecklenburg
	 Morgan Keegan & Company, Inc.
	 Daniel J. Jr. and Melissa A. Nordman
	 Gerald N. and Patricia A. Padawer
	 Terry J. and Kim T. Schott
Paul E. Valentino
	 Stephen Gulyas
IN HONOR OF:
Nick Andrews
	 Kathi Holbrook
John Bates
	 Robin Ballenger
Chet Carey
	 Mr. and Mrs. Geoffrey Carey
Patrick Collins
	 James Collins
John DeAtley
	 Chris H. Hansen, CFP and
	 John M. Britton of Personal
	 Choice Financial Advisors
Barth Engelman
	 Marge Engleman
Lisa Freeman
	 Joan Tibbetts
Craig Horn
	 Jo Williams
John Johnson
	 Ellen J. Sharp
Rose Kaput
	 Stephen Gulyas
Richard H. Keeter
	 David Michael Keeter
Jung Liu
	 Anchi Miller
David Loew
	 Lisa Wilson
Lois Lynch
	 Isaac Lynch, Jr.
Thomas Mathews
	 Carrol G. Mathews
Donald Mitchell, Jr.
	 Donald Mitchell, Sr.
Peny Nading
	 Elaine Davis
Edith Perschall
	 Janice M. Stanley
Dave Peters
	 David W. Peters
Mari Quigley-Miller
	 Jonna DeBlasio
The Ross Family
	 Heidi Ross
James Roth
	 Barbara R. Roth
Faye and John Schleter
	 Sandra Schleter
Charles Shaw
	 K. Stern
Joseph Smith
	 David and Gail Cohen
Tinnitus sufferers
	 Janie P. Barnett, Au.D.
Tinnitus victims of war
	 Richard and Louise E. LaRosa
Katy Thatch
	 Donna Brown
Brooklyn Marie Thomas
	 Jack A. Vernon, Ph.D. and Mary B. Meikle, Ph.D.
Peter J. Van Loon
	 Greg Sorter
Jack A. Vernon, Ph.D.
	 James L. and Gail M. Shinn
Jack A. Vernon, Ph.D. and
Mary B. Meikle, Ph.D.
	 Richard J. Salvi, Ph.D.
Daniel Williams
	 Alberta F. Williams
Robert Williams
	 Derwin and Charlotte Williams
Sallyann Wolf
	 Alan C. Niederfringer
Matching Corps
Allstate
Chicago Tribune Foundation
Gap, Inc.
GE Foundation
Illinois Tool Works Foundation
Lorton Data, Inc.
Microsoft
Oracle
Portland General Electric Co.
Symetra Financial
Corporate Visionaries
$1,000 to 4,999
Corporate Leaders
$500 to 999
Clear Products, Inc.
Cooper Mountain Wines
Flexion Therapeutics, Inc.
Free-credit-reports.com, Inc.
Paddy’s Bar & Grill
Corporate Members
$250 to 499
A1 Retrofit LLC
Amplisound
Bizon Nursery
Elliot Law Offices
James Robert Construction, LLC
Lagunitas Beer
NeuroSystec Corporation
Pacific Marketing and Publishing
Trademark Landscapes, Inc.
Now you can support ATA’s work with safe,
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Bilsom Thunder T3 Ear Muffs NRR-30dB
($19.95 ATA Members / $21.95 Non-Members)
Bilsom Thunder T3 ear muffs have a strong noise reduction rating (NRR) of 30dB, making them
perfect for noisy environments. Their dielectric construction is suitable for MRI machines and
all workplaces. Features patented Air Flow Control technology for optimal attenuation across all
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Remington Kids Ear Muffs NRR-22dB
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Remington Youth ear muffs are lightweight with a ventilated headband. Their dielectric construc-
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mended for children age 5 through teens. Color: Blue-Green / Yellow trim
SparkPlugs Ear Plugs 5-pair set NRR-33dB
($2.50 ATA Members / $3.00 Non-Members)
SparkPlugs ear plugs are made of extra-soft, extra-light foam and are the official ear plugs of
NASCAR! Their tapered shape fits easily in the ear canal, and seals gently and snugly without
pressure. SparkPlugs ear plugs offer a high NRR-33dB, making them suitable for most noisy
environments. Color: Mixed
Ohropax Classic Moldable Wax Ear Plugs 6-pair set NRR-22dB
($4.95 ATA Members / $5.50 Non-Members)
Ohropax Classic ear plugs have been an established, German-made noise protection product since
1907. These wax moldable ear plugs can be adjusted to fit every auditory canal and considerably
reduce the effects of noise pollution with a noise reduction rating of 22dB. Six pairs in metal
carrying case. Color: Peach
Etymotic Research ER-20 Hi-Fidelity Ear Plugs NRR-20dB
($10.95 ATA Members / $11.95 Non-Members)
Etymotic ER-20 Hi-Fi Natural Sound Ear Plugs feature patented Hi-Fi technology that lets you
hear all frequencies clearly, but at a lower volume level. Reduce sound levels approximately
20dB. ER-20 ear plugs are washable, reusable and durable. With proper care they will last for
months even with daily use. Color: White plug, clear stem
Etymotic Research ER-20 Baby Blues Ear Plugs NRR-20dB
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feature patented Hi-Fi technology that lets you hear all frequencies clearly, but at a lower volume
level. Reduce sound levels approximately 20dB. Baby Blues plugs are washable, reusable and
durable. With proper care they will last for months even with daily use. NOT recommended for
children under age 5. Color: Blue plug, clear stem
Tinnitus: Turning the Volume Down (Revised & Expanded Edition)
by Kevin Hogan, Psy.D., and Jennifer Battaglino, LCSW
($22.95 ATA Members / $24.95 Non-Members)
This revised and expanded book contains a decade of proven strategies for quieting the
noise in your head. Details the evolution of tinnitus research and discusses various
causes and tinnitus treatment options. (260 pages, soft cover)
Noise and Military Service: Implications for Hearing Loss and Tinnitus
by Larry E. Humes, Lois M. Joellenbeck and Jane S. Durch
($59.95 ATA Members / $62.95 Non-Members)
Findings are presented from studies on hazardous noise in military settings, levels of
exposure necessary to cause hearing loss or tinnitus, risk factors, the timing of the
effects of noise exposure on hearing and the adequacy of military hearing conservation
programs, including audiometric testing. (338 pages, soft cover)
Hyperacusis: Mechanisms, Diagnosis, and Therapies
by Davis M. Baguley, Ph.D., and Gerhard Andersson, Ph.D.
($68.95 ATA Members / $69.95 Non-Members)
Explores what is currently known about hyperacusis from the disciplines of neurosci-
ence, psychology and audiology. The authors integrate theory with practice and
provide coherent analyses of current research. (114 pages, hard cover)
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Tinnitus Today Aug 2009

  • 1. August 2009Vol. 34, Number 2 Abroadand hereathome, scientistsmoveus closertoacure. A publication of the American Tinnitus Association
  • 2. 2 Tinnitus Today | August 2009 Hello. I’m the same Lisa, now with my married name of Hutton! Thank You for Taking ATA’s Member Survey We are very grateful to the 1,137 members who responded to our online Member Survey! Your thoughts are an important element in ATA remaining an informed and successful organization. Look for survey results at www.ata.org later this summer and in the December 2009 Tinnitus Today. Selected Survey Highlights Please see some early survey results on page 4 of this issue. ATA’s Support Network Check out the updated listings at www.ata.org or contact me at lisa@ata.org or (800) 634-8978 x219 to learn more. We send e-mail updates to inform and remind our members of upcoming support group meetings, including those with guest speakers. We send other important ATA updates as well. Please call or e-mail me if you would like to add your e-mail address to the list. National Tinnitus Awareness Week (TAW) The 2009 TAW activities truly reflected its theme, “What YOU Can Do To Cure Tinnitus.” Individuals in their own towns, cities and states celebrated TAW, raising awareness about tinnitus and the urgent need for a cure. A few TAW activities included: n ATA held its first ever Walk For A Cure (see page 14) and “Hope & Help for Living With Tinnitus,” a seminar, (see page 10) in Southern California on May 16 – both events organized by dedicated volunteers. Members Corner Lisa F. Hutton, ATA Manager of Member Services n Earl O. Hutchinson, political activist, tinnitus sufferer and radio personality, interviewed Scott C. Mitchell, J.D., ATA’s recent past board chair, on “The Hutchinson Report,” broadcast on radio station 1460 AM in Los Angeles and streamed on KTYM.com. Scott addressed ATA’s mission to cure tinnitus. The interview is available at www.ata.org/news-pubs. n ATA honored its Congressional Champions (see page 18). n Linda Beach, co-coordinator of the South New Jersey Tinnitus Support Group, and her husband, State Senator Jim Beach (D-NJ 6th District), cham- pioned the Tinnitus Awareness Week resolution declared in New Jersey’s state legislature. Your Members Section and Health Professional Updates Visit your Tinnitus Information Center in the Members Section – www.ata.org/members – with its robust archive of Tinnitus Today articles and all the health profes- sionals on ATA’s listing. We recently added icons (at right) to the listing to accurately reflect each health care professional and/or clinic’s type of ATA membership. ATA does not award professional credentials, so please consider our listing as a starting point rather than a referral list. We include information provided by various professionals so that you can contact them and select someone whose services best fit your needs. We update the listings on a regular basis and when available, provide a link to a professional’s Web site where they often list their training and treatment options in more detail. Research Champions Professional Members ATA member As ATA members, you are the cornerstone of our organization and the reason for our commitment to a cure. Again, thank you for your ongoing support of our mission and for renewing your ATA membership.
  • 3. 3August 2009 | Tinnitus Today Editorial and advertising office: American Tinnitus Association, P.O. Box 5, Portland, OR 97207 • (503) 248-9985, (800) 634-8978 • tinnitus@ata.org • www.ata.org Michael Malusevic, Executive Director Nina Rogozen, Editor Tinnitus Today is published three times a year, in April,August and December, and mailed to American Tinnitus Association members and donors. Circulation is rotated to 75,000 annually. The American Tinnitus Association is a nonprofit human health and welfare agency under 26 USC 501(c)(3). ©2009 American Tinnitus Association. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the Publisher. ISSN: 0897-6368 (print). ISSN: 1530-6569 (online). Board of Directors Gary P. Reul, Ed.D., Chair, Issaquah, Wash. Mark K. Johnson, J.D., Vice Chair, Anchorage, Alaska Barbara Kennedy, Secretary, Mays Landing, N.J. J. Scott Simons, Treasurer, Sioux Falls, S.D. Anthony T. Cacace, Ph.D., Detroit, Mich. Neil Cherian, M.D., Cleveland Heights, Ohio James O. Chinnis Jr., Ph.D., Warrenton, Va. Michelle Dapolito, Hoboken, N.J. Marsha Johnson, Au.D., FAAA, Portland, Ore. Thomas J. Lobl, Ph.D., Valencia, Calif. Scott C. Mitchell, J.D., C.P.A., Houston, Texas Michael O’Rourke, Arlington, Va. Michael J. A. Robb, M.D., Phoenix, Ariz. Joseph Trevisani, New York, N.Y. Honorary Directors Peter & Joan Graves, Beverly Hills, Calif. Mark O. Hatfield, U.S. Senate-Retired, Washington, D.C. William Shatner, Los Angeles, Calif. Jack A. Vernon, Ph.D., Portland, Ore. Scientific Advisory Committee Anthony T. Cacace, Ph.D., Chair, Detroit, Mich. Paul J. Abbas, Ph.D., Iowa City, Iowa Thomas J. Brozoski, Ph.D., Springfield, Ill. Donald Caspary, Ph.D., Springfield, Ill. Craig Formby, Ph.D., CCC-A, Tuscaloosa, Ala. Donald A. Godfrey, Ph.D., Toledo, Ohio James (Jay) W. Hall III, Ph.D., FAAA, Gainesville, Fla. James Henry, Ph.D., Portland, Ore. James A. Kaltenbach, Ph.D., Cleveland, Ohio Paul R. Kileny, Ph.D., FASHA, Ann Arbor, Mich. Robert A. Levine, M.D., Boston, Mass. Craig W. Newman, Ph.D., Cleveland, Ohio Jay F. Piccirillo, M.D., FACS, St. Louis, Mo. Michael J. A. Robb, M.D., Phoenix, Ariz. Jay T. Rubinstein, M.D., Ph.D., Seattle, Wash. Roger A. Ruth, Ph.D., Charlottesville, Va. Susan Shore, Ph.D., Ann Arbor, Mich. Hinrich Staecker, M.D., Ph.D., Kansas City, Kan. The Publisher reserves the right to reject or edit any manuscript received for publication, and to reject any advertising deemed unsuitable for Tinnitus Today. Acceptance of advertising by Tinnitus Today does not constitute endorsement of the advertiser, its products or services, nor does Tinnitus Today make any claims or guarantees as to the accuracy or validity of the advertiser’s offer. The opinions expressed by contributors to Tinnitus Today are not necessarily those of the Publisher, editors, staff or advertisers. The American Tinnitus Association exists to cure tinnitus through the development of resources that advance tinnitus research. August 2009Vol. 34, Number 2 TABLE OF CONTENTS REGULAR FEATURES 4 Passing the Baton: I’ve Had a Wonderful Year as CEO Gary P. Reul, Ed.D. 6 Letters to the Editor 24 Questions and Answers Jack Vernon, Ph.D. 26 Special Donors and Tributes SPECIAL FEATURES 2 Members Corner Lisa F. Hutton, ATA Manager of Member Services 5 New Board Transitions at ATA Katie Fuller, ATA Executive and Development Associate 8 Family Series: Adaptability Helps the Reuls Live with Acoustical Trauma Nina Rogozen, Editor, Tinnitus Today 10 Hope and Help for Living with Tinnitus: A Seminar Recap 11 Can a Simple Kiss on the Ear Cause Auditory Problems? Levi A. Reiter, Ph.D. 14 A Walk in the Park and Across America 16 The Incidence of Tinnitus in U.S. Veterans Continues to Escalate 18 Honoring New Friends in our Nation’s Capital Jennifer DuPriest, ATA Associate Executive Director FOCUS ON RESEARCH 12 Highlights: Selected 2008-2009 Tinnitus Research Studies Nina Rogozen, Editor, Tinnitus Today and Daniel Born, ATA Director of Research and Special Projects 17 ATA Member Participates in Tinnitus Clinical Trial: A Q&A with Mark Church about rTMS Daniel Born, ATA Director of Research and Special Projects and Jennifer DuPriest, ATA Associate Executive Director 20 Tinnitus and Hyperactivity in Dorsal Cochlear Nucleus Fusiform Paul G. Finlayson, Ph.D. 21 Clinical Trial of Acamprosate for Tinnitus William Hal Martin, Ph.D., and Yong-Bing Shi, M.D., Ph.D.
  • 4. 4 Tinnitus Today | August 2009 Passing the Baton: I’ve had a Wonderful Year as CEO Selected Highlights from the 2009 Member Survey Gary P. Reul, Ed.D., Chair, ATA Board of Directors I am very pleased to announce that on July 1, 2009, ATA named Michael Malusevic as the new Executive Director and Jennifer DuPriest as Associate Executive Director. (This represents a change in leadership titles.) Michael and Jennifer have been with ATA for quite some time and share a strong commitment to our mission and to the smooth, effective running of this wonderful organization. As chair of the board, I look forward to continuing to work with Michael, Jennifer and the entire staff over the coming years. Go to www.ata.org to read more about these exciting changes. My heartfelt parting words are simple, but important: Please con- tinue supporting ATA so our goal of a cure becomes a reality for all of us. Simply use the convenient envelope in the center of Tinnitus Today or go to www.ata.org and click on “Donate Now.” I believe that during my tenure as CEO, I fulfilled the board’s expec- tations and I look forward to my second retirement. This change will accommodate my health chal- lenges and eliminate frequent and extended commuting between Portland, Ore. and Seattle, Wash. However, I am not leaving ATA, only changing positions. On July 1, 2008, I was poised to become chair of ATA’s Board of Directors. As fate, luck or karma would have it, the board asked me to become the organization’s Chief Executive Officer (CEO) on June 28, 2008. They agreed that I had the right experience, with 20 years as an administrator and a doctorate in leadership, to step into the role. At 71 years of age, I have had a life full of work experiences; being ATA’s CEO was the most reward- ing and satisfying. Of particular joy was directing such an experienced and talented staff; interacting with so many people with tinnitus from all over the world; and working with a great board and its very skilled chair, Scott C. Mitchell, J.D. I am pleased that my tinnitus and hyperacusis allowed many members to feel a kinship with me. I thank all of those who sent me notes or e-mails and those with whom I had interesting telephone conversations about tinnitus. Top three things members want from ATA: n A cure for tinnitus n Ways to manage tinnitus n Advocacy efforts with national lawmakers and leaders Greatest sources of tinnitus information: n Tinnitus Today n www.ata.org Most helpful sections of Tinnitus Today: n Research articles n Treatment articles n Coping and managing tinnitus n Q&A Most common tinnitus effects on day-to-day life: n Annoying n Trouble sleeping n Trouble concentrating Tinnitus sounds like: n Ringing n Hissing n Buzzing n High-tension wire Responders with hearing loss: n 73 percent Gender of survey responders: n Male – 71 percent n Female – 29 percent
  • 5. 5August 2009 | Tinnitus Today New Board Transitions at ATA Katie Fuller, ATA Executive and Development Associate She says that her favorite part of being a board member has been visiting Portland, Ore. (ATA’s head- quarters) and developing ways to deal with tinnitus. Maggie plans on “being involved with ATA as long as they put up with me.” A Warm Welcome to ATA’s New Board Members Michelle Dapolito, Director of Marketing at FX Solutions in Saddle River, N.J., joined the board July 1. Michelle has over 12 years experience in online marketing and advertising and Web site design. Before coming on as a director, Michelle volunteered her time to help ATA’s Web committee revamp our site, www.ata.org, and continues to be instrumental in its changes and further development. We are pleased to have Michelle’s contagious energy and commitment to the organization on board. We also welcome Marsha Johnson, Au.D., FAAA, a practicing audiol- ogist in Portland who founded the Oregon Tinnitus and Hyperacusis Clinic in 1997. Marsha brings to ATA over ten years of clinical knowledge and experience in caring for patients with tinnitus, hyperacusis and/or hearing loss. Her sincere desire to help those who are suffering will prove indis- pensable to the organization. A New Chair July 1, the start of the 2009-2010 fiscal year, brought major changes to ATA’s Board of Directors. As he addresses in his farewell column (see “Passing the Baton,” page 4) Gary P. Reul, Ed.D., has stepped down as ATA’s Chief Executive Officer and rejoined the board as chair. A Huge Thank You Scott C. Mitchell, J.D., just com- pleted three dedicated years as chair of ATA’s Board of Directors. “With my term as board chair coming to a close,” reflects Scott, “I must say that it has been a privilege to work with the ATA staff. To paraphrase Winston Churchill, ‘Never have so many been helped so much by so few.’ Gary’s move from CEO to chair of the board assures me that ATA will continue to focus on finding a tinnitus cure, and in the meantime, provide compassion- ate help to those who are suffer- ing. With our staff, and Gary still involved in leadership, we could not be in better hands.” ATA thanks Scott for his excellent years as chair and the extraordi- nary time and effort he donated on behalf of ATA and the tinnitus research community. We are very pleased that Scott is continuing to work with ATA as a board director. A Fond Farewell to Two Long- Standing Board Members John R. Bates and Margaret (Maggie) F. Peak, Ph.D., have been on the Board of Directors for a combined total of twelve years. John leaves after serving for six years, two of them also on the finance committee. He is currently presi- dent and CEO of Flint Resources Company, LLC, in Tulsa, Okla., whose principal subsidiary is com- mercial construction, building large projects, such as schools, hospitals and stadiums throughout the south- ern, southwestern and western United States. John says that the best part of serving on ATA’s board was having the opportunity to work with extremely professional board members, staff and research- ers. When asked how long he plans on being involved with ATA, John says, “We don’t have ‘the cure’ [yet] so the job is not finished. Therefore, I will stay involved through ATA’s Advisory Council.” Margaret (Maggie) F. Peak, Ph.D., has been involved with ATA since 1975. She is a champion of tinnitus suffer- ers, particularly veterans, and has helped guide the organization’s focus toward fund- ing research and developing the Roadmap to a Cure. Maggie is the Assistant Chief of Audiology and Speech Pathology at VA Gulf Coast Veterans Health Care System in Biloxi, Miss., where she splits her time between seeing patients and managing the department’s admin- istrative operations.
  • 6. 6 Tinnitus Today | August 2009 Letters to the Editor Alternative Tinnitus Treatments I am a 52-year-old man who has been living with severe tinnitus for over 25 years. Exposure to loud music, when I was a rock guitarist in my 20s, caused my tinnitus. I also have genetic hearing loss (my father and grandfather were hard of hearing in their later years). For the last year, I have been wearing hearing aids. I originally went to a doctor in California who told me that there was nothing that could be done. The with my tinnitus. Meditation and personal growth work did the most good. Recently, I went to a doctor who works with Quantum Health, a diagnostic computer system designed to identify energy imbalances, food sensi- tivities/allergies and other risk factors. He gave me a long list of foods to avoid and a plethora of herbs, vitamins and minerals, which I adhered to for six weeks. I could only eat turkey, green vegetables and a few fruits. I had to avoid everything else, including various spices, oils, caffeine, dairy, alcohol and sugar. After the six weeks, I felt physically better than I have ever felt – I had tons of energy and felt mentally clear and very strong. At the same time I was doing this Quantum Health diet, I went to see a highly recommended Chinese acupuncturist and spiritual healer. Within a few weeks – and I don’t know how or why – I no longer needed my hearing aids. I still experience ringing in my ears, which has not signifi- cantly improved, but my hearing definitely has. I would like to see professionals give these alterna- tive approaches a chance and even research their effectiveness in treating tinnitus. Lon Cohen Marina del Rey, Calif. One Woman’s Positive Experience with Psychotherapy Eye Movement Desensitization and Reprocessing (EMDR) is a powerful method of psychotherapy. Practitioners use it for a wide variety of problems. I have been seeing a psychotherapist in Chicago who is on the forefront of using EMDR for tinnitus. I have had tinnitus for twenty years. Initially the sound was similar to a smoke alarm going off; then it seemed like a million cicadas; and now it is akin to a teakettle. Like others, my original ear, nose and throat doctor (ENT) told me to either “deal with it or go crazy.” I dealt with it and by the fall of 2008, I noticed an alarming increase in my ringing. I actually In each issue, we include letters from our members about their experi- ences with tinnitus and with non-traditional treatments. We do so in the hope that the information offered might help our readers. Please read these anecdotal reports carefully.When we include letters about treatments, consult with your physician or health care advisor and decide for yourself if a given treatment might be right for you.As always, the opinions expressed are strictly those of the letter writers and do not reflect an opinion of or endorsement by ATA. Send your letters to Nina Rogozen, Editor at nina@ata.org or to Editor, Tinnitus Today, ATA, P.O. Box 5, Portland, OR 97207. best I could hope for was to protect what hearing I had left. More recently I was shocked and dismayed to find, that after 25 years, no one I spoke with had any information whatsoever with regard to alterna- tive healing methods. They knew nothing about diet, acupuncture, cranial sacral work, meditation, chakra clearing, visualization, psychotherapy, holis- tic healing or any other alternative treatments. I had tried all of these methods to some degree with vary- ing levels of success, at least with regard to coping
  • 7. 7August 2009 | Tinnitus TodayATA does not endorse or recommend any tinnitus products or treatments. Advertisement ended up in the emergency room due to Lyrica®, the medication erroneously prescribed for a separate, misdiagnosed condition, which made my tinnitus uncontrollable. That same fall, my new ENT referred me for EMDR treatments. My initial ses- sions began with an imag- ined environment – a calm location where I could start to mentally decrease my tinnitus sounds. Sessions after that included color association, breathing techniques, visualization/ meditation and eye movement exercises resulting in decreased anxiety. I also learned to take the power away from my tinnitus; to stimulate the right and left sides of my brain; and many other tools to decrease both the sound and stress of my tinnitus. EMDR has made a significant difference in my lifestyle and coping mechanisms. I am able to use the many tools I learned from my sessions. I have noticed a differ- ence in my condition since beginning EMDR treatment. I can manage it better and although I still notice some sound fluctuations, my anxiety has decreased. I’m glad to be sharing this infor- mation with others who suffer with tinnitus. Donna Marsh Orland Park, Ill. Editor’s note: EMDR is a form of psychotherapy developed to help resolve symptoms resulting from disturbing and unresolved life experiences. It includes a comprehensive and integrative psychotherapy approach. Read more at www.emdr.com/briefdes.htm.
  • 8. 8 Tinnitus Today | August 2009 Gary and Barbara Reul enjoy traveling. They’ve been to 52 countries, most recently to China and Sweden. Like most of us, they bring home remind- ers of their adventures. But one day in 1993, they brought back something from Florida that neither of them expected – Gary’s debilitating tinnitus and hyperacusis (a decreased tolerance to some normal sounds that makes them seem unbearably loud). Barbara, a travel agent, heard about a great-sound- ing Florida Everglades experience – an airboat ride to a quiet spot with beautiful birds and animals. The travel brochure did not mention the boat’s extremely loud engine and horn or the risk of tinnitus and hyperacusis, which struck Gary on the spot. That night, without the acoustical distractions on the street, the quiet of their hotel punctuated Gary’s agony. “I felt like a caged animal; I was climbing the walls,” he remembers. “I paced and held my head while a high-pitched noise filled my ears.” Tinnitus and Hyperacusis Changed Their Lives Many of Gary’s friends did not understand the prob- lem, which left him feeling very alone with his new disability. At work he endured large, intolerably noisy meetings by sitting in the hallway. “I had to constantly explain to people why I was there,” says Gary. “However, this was a learning experience for others and it drew out many who had tinnitus.” “At first Gary’s problems were very stressful,” remembers Barbara. “I felt frustrated and often on the verge of tears. I blamed myself for arranging the airboat ride and felt guilty for not experiencing these problems myself. This was the roller coaster ride of our lives, which seemed like a blur of depression.” That fateful trip robbed the Reuls of some activities they had always enjoyed together. At first, Barbara would not leave Gary at home and venture out to plays, movies or other places his ears could not tol- erate. No more Super Bowl parties, church, baseball games, weddings, funerals or movies. “We can’t talk in the car because I have to wear earmuffs if we go over twenty miles an hour,” laments Gary. “This struggle is also very painful because Gary looks the A Series on Families Living With Tinnitus We often have little influence on a loved one’s chronic condition. However, we can learn about the issues, remain supportive and take care of our own well-being. For some, working to enhance treatments, find cures and raise awareness are ways to cope and create hope. This is certainly true in the tinnitus community. This is the third story in our series on families made up of members with and without tinnitus. The series explores their experiences, the feelings that penetrate their lives and the frustrations they face. It also illuminates some of the solutions that diminish their stress and allow families to settle into a “new normal.” Adaptability Helps the Reuls Live with Acoustical Trauma By Nina Rogozen, Editor, Tinnitus Today
  • 9. 9August 2009 | Tinnitus Today same, so some friends still don’t really understand,” says Barbara. Gary Turned to the American Tinnitus Association Part of the Reuls’ frustration has been the lack of treatment options. Doctor after doctor told Gary to “live with it.” He took an antidepressant, which helped for a while. He tried herbal medications, including Ginkgo biloba for two years, which did not give him any relief. Counseling helped some and Tinnitus Retraining Therapy (TRT) helped his hyperacusis, but not his tinnitus. Desperate for guidance, Gary contacted the American Tinnitus Association for emotional support and informed resources. He eagerly absorbed infor- mation in brochures and archived articles and on CDs. He shared these resources with his family, who were anxious to understand. His involvement with ATA grew as Gary served as chair of ATA’s program commit- tee, vice chair of the Board of Directors, ATA’s CEO for the 2008-2009 fiscal year and now chair of the board. Developing a New Normal “We have adapted to a new normal, a way of living altered from our pre-tinnitus years, yet one that gives us as much satisfaction as possible,” says Barbara. “We aim for an acceptable balance between what I do and what he can’t do.” Gary has encouraged Barbara’s “emancipation” from her hesitancy to enjoy activities without him. Gary is not without the stress of tinnitus and hyperacusis, but his and Barbara’s adaptability and their dedication to each other’s happiness is the engine that created their new normal. What seemed to help the Reuls the most was time to adjust to lifestyle changes. Gary uses earplugs and earmuffs to keep out loud sounds he cannot tolerate. Lecturing about tinnitus and hyperacusis at their retirement community helps him as well. The Gift of Experience The Reuls have some good ideas that may help those of you with tinnitus in your family. If you are living with hyperacusis and crave silence, as most of us do, remember that being in the midst of some noise may actually help you become less sensitive to sound. Try going to hotel restaurants, which tend to be quieter, as are many eating estab- lishments between 2 p.m. – 5 p.m. And call ahead to inquire about quiet seat- ing. If you are anxious and/ or depressed, discuss the possible use of medication with your health care pro- fessional. Always keep ear- plugs or earmuffs nearby. Use them when necessary, for instance, like Gary does around his playful grand- daughter. Ask your dentist to drill for 10 seconds, stop for 10 seconds, etc. to reduce noise trauma. “Use ATA materials to educate others about what you are hearing and experiencing,” concludes Gary. Barbara adds, ”Be as calm and understanding as possible.” Committed to Each Other and All of Us Gary and Barbara believe in ATA’s mission and under- stand personally how important everyone’s support is to bolstering tinnitus and hyperacusis research that will lead us to a cure. They encourage all families and indi- viduals to contribute to this very important cause. “Wehaveadaptedtoanewnormal, awayoflivingalteredfromour pre-tinnitusyears,yetonethatgives usasmuchsatisfactionaspossible.” ~ Barbara Reul To contribute to ATA’s mission of silencing tinnitus, simply use the envelope in the center of Tinnitus Today. Remember, what may seem like a small contri- bution makes a big difference toward curing tinnitus. Gary and Barbara Reul at The Bund (Waitan), one of the most recognizable architectural symbols of Shanghai, China, located at the west bank of a bend in the Huangpu River.
  • 10. 10 Tinnitus Today | August 2009 The Los Angeles Tinnitus Support Group cel- ebrated its 25th anniversary in a way consistent with its ongoing focus – providing help and hope to tinnitus sufferers. On May 16, 2009, led by support group leader Nelly Nigro, the group commemorated its 25 years of service by deliver- ing “Hope and Help for Living with Tinnitus,” a public seminar held at the VA Greater Los Angeles Healthcare System. The daylong seminar, sponsored by the American Tinnitus Association and supported by House Ear Institute and Advanced Bionics, featured an impressive list of tinnitus experts. They covered a variety of sub- jects, including current tinnitus research, existing therapies, development of novel technologies, tinnitus in the military, ATA-supported research and the Roadmap to a Cure. Also discussed were drug therapies, drug development and practical strategies to effectively manage one’s tinnitus. Additionally, the event recognized Nelly Nigro for her many years of service to ATA and the support group, and Mr. D.G. Gumpertz for his financial contribution to the seminar and his ongoing com- mitment to and support of ATA’s mission. Our deepest thanks to Nelly Nigro and D.G. Gumpertz for their leader- ship and support. And a heartfelt thank you to our speakers: Jim Boswell, Ph.D., CEO, House Ear Institute Jeff A. Carroll, Ph.D., Director, Tinnitus and Hypercusis Treatment Center, University of California, Irvine Dhyan Cassie, Au.D., FAAA, Ear, Nose and Throat Professional Associates Hamid R. Djalilian, M.D., Associate Professor of Clinical Otolaryngology and Director of the Division of Neurotology and Skull Base, University of California, Irvine Medical Center Jennifer DuPriest, Associate Executive Director, ATA John W. House, M.D., President, House Ear Institute Thomas J. Lobl, Ph.D., VP of Research & Development, NeuroSystec Corporation and member, ATA Board of Directors David I. Meyer, Ph.D., Executive VP of Research, House Ear Institute Scott C. Mitchell, J.D., recent past chair, ATA Board of Directors Eric Viirre, M.D., Ph.D., Associate Adjunct Professor of Surgery, Division of Otoloaryngology, University of California, San Diego “Hope and Help for Living with Tinnitus”: A Seminar Recap Left: Scott C. Mitchell, J.D., recent past chair, ATA Board of Directors and Nelly Nigro, chair, seminar planning committee and Los Angeles Tinnitus Support Group leader. Center: John W. House, M.D., House Ear Institute. Right: Jennifer DuPriest, Associate Executive Director, ATA, and Marcia Harris, first Los Angeles Tinnitus Support Group leader. Dan Burbach is a welcome addi- tion to the ATA staff. He became our fulfillment coordinator in the winter of 2009, soon after we moved to our new offices. Dan is in charge of ATA mailings, product sales shipments and data entry. He has a drive to make ATA’s distribution function even more fluid and continually flexible. Dan graduated from the University of Oregon in 2005 with a double major in political science and art. His experiences in college led him toward a path in the nonprofit world and motivated him to give back to the community. He spent a year and a half working for Habitat for Humanity through AmeriCorps in New Orleans, La. and Biloxi, Miss. When not working, Dan is out exploring his neighborhood, traveling, reading and enjoying time with friends and family. Welcome to Dan Burbach, ATA’s Fulfillment Coordinator
  • 11. 11August 2009 | Tinnitus Today Although ear kissing has undoubtedly been around as long as humans, the sur- prisingly pathologic result of this simple gesture first appeared in print as recently as August 2008.3 The initial case involved a four-year-old child who hugged her mom and gave her a loving smooch on her left ear canal. Mom’s immediate experience was severe, deep ear pain; loud, screeching tinnitus; total hearing loss; and facial twitching in the region of the ear – all on the left side. Within the next several hours, her total hearing loss recovered to a stable 35 dB SNHL in the middle hearing frequencies. The loss remains at that level two and a half years later. The patient con- tinued to suffer from tinnitus and facial spasms for about one year. During that time she also developed hyperacusis and distortion in the clarity of her hear- ing in the left ear. Today, the SNHL, hyperacusis and distortion remain. The tinnitus is now noticeable pri- marily in quiet surroundings, and the facial spasms occur only after experiencing excessively loud noise at a wedding, live concert or other noisy venue. This first case study received a good deal of media coverage, and as a result, dozens of people came forth with their very similar stories. One indi- vidual was given a happy Mother’s Day “peck” on the ear by her loving husband, only to suffer immediate hearing loss, tinnitus and hyperacusis. In another case, a parent received a traditional, but misdirected, farewell kiss on the cheek by her son- in-law, which inadvertent- ly landed on her ear. The Can a Simple Kiss on the Ear Cause Auditory Problems? result was SNHL, tinnitus and hyperacusis. To date, I have examined over one dozen cases rang- ing from 10 to 81 years of age. All show the same three symptoms: SNHL, tinnitus and hyperacusis. There are three intriguing questions that I would like to address: 1. If this phenomenon is so old and so common, why has it taken so long to be discovered and published? 2. What is it about a kiss to the ear that causes such devastating consequences? 3. What can be done to treat or prevent this problem? The answer to the first question is professional denial. Each patient who contacted me to have an ear-kiss injury evaluated, confided that a physician had previously denied their claim that a kiss caused their hearing problem. When several patients came across my “kiss” research, they felt validated – no, they were not imagining things. Their doctors’ pre- conceived notions about the harmlessness of a kiss had prevented further investigation into the matter via scientific or medical research. The second question regards the cause of this ear pathology, which has been termed “REKS” for Reiter’s Ear-Kiss Syndrome.4 Research indicates that a kiss to the ear canal creates suction, which pulls the eardrum and ossicular chain (small inner-ear bones that transmit sound) forward. This in turn pulls the stapes (one of the ossicular chain) away from the inner ear, causing a tsunami-like turbulence in the inner ear fluids. This damages the Levi A. Reiter, Ph.D., Hofstra University, Hempstead, New York The answer to the question posed by this title is an unfortunate “yes!” Tinnitus, hyperacusis and permanent sensorineural hearing loss (SNHL) can result from a single, affectionate kiss to the ear.1,2 Levi A. Reiter, Ph.D. continued on page 25
  • 12. 12 Tinnitus Today | August 2009 Tinnitus Research: Tales From a Grand Meeting at Grand Island, N.Y.1 United States, December 2008 Anthony T. Cacace, Ph.D., is the recent past editor of the American Journal of Audiology and chair of ATA’s Scientific Advisory Committee. In his words, “Scientific conferences play an important role in updating knowledge and improving our conceptualizations of selected topics of interest. They are a healthy way for promoting discussion/debate and providing seg- ues for the advancement of science.” In June 2007 the conference, “Advances in Tinnitus Assessment, Treatment and Neuroscience Basis,” was a huge success. Scientists from Belgium, Canada, China, Finland, Germany, Italy, Japan, South America and the United States attended and participated in the exchange of knowledge, research programs and enthusiasm. Six prominent researchers, representing their indi- vidual research teams, presented papers published in the December 2008 issue of the American Journal of Audiology. Topics included: (1) The dorsal cochlear nucleus (DCN) may play a pivotal role in tinnitus development; (2) Anatomical and neurobiological evi- dence of auditory/somatosensory system interactions; (3) Synaptic plasticity at the level of the DCN can serve as a mechanism for tinnitus generation and tinnitus may be a multisensory phenomenon; (4) Using a gap detection startle-reflex procedure in rats to demonstrate behavioral evidence of tinnitus and perhaps hyperacu- sis; (5) The cortical representation of tinnitus is mani- fested by increased synchrony between sets of neurons; and (6) Identifying subgroups of tinnitus patients as a way to improve treatment outcomes. Cacace sums up the value of such a conference: “… The convergence of the basic sciences and the clinical domain … can contribute to advancing this area.” Highlights: Selected 2008-2009 Tinnitus Research Studies Nina Rogozen, Editor, Tinnitus Today and Daniel Born, ATA Director of Research and Special Projects Identifying Tinnitus Subgroups to Maximize Treatment2 United States, December 2008 Richard Tyler, Ph.D., and his research team began with the premise that it is “important to uncover tinnitus subgroups to identify subsets of patients most likely to benefit from different treatments.” By reviewing strategies for subgrouping based on etiology, subjective reports, the audiogram, psychoa- coustics, imaging and cluster analysis, they obtained preliminary results. The team’s analysis of 246 participants helped them determine 26 categorical and 25 continuous variables. Results suggested four major patient subgroups – those who have (1) constant, distressing tinnitus; (2) varying tinnitus that is worse in noisy environments; (3) learned to manage their condition and whose tinnitus is not influ- enced by touch (somatic modula- tion); and (4) tinnitus that is worse in quiet environments. The team concluded that it is possible to identify subgroups of tinnitus patients using statistical approaches. Potential follow up would explore clinical tinnitus treatment trials based on utilizing subgroup analysis. Comparing Different Frequencies of Daily Repetitive Transcranial Magnetic Stimulation for Treating Tinnitus 3 Egypt, February 2008 Repetitive transcranial magnetic stimulation (rTMS) (see page 17) uses different frequencies – 1 Hz, 10 Hz, 25 Hz and sham (occipital, 1 Hz) – to treat tinnitus. To better understand the effects of these Once again we bring you our yearly sampling of tinnitus research being conducted in the United States and abroad. Each study gives us hope that we are moving closer and closer to the foundations of better treatments, and ultimately a cure. This year, we include a glossary of words and phrases to make it easier to understand some of the more technical references in this review (see page 23). You will find these items italicized in the body of the text below.
  • 13. 13August 2009 | Tinnitus Today various frequencies, Eman M. Khedr, M.D., and his research team randomly divided 66 patients, all with chronic tinnitus, into four treatment groups. All patients received daily rTMS treatment over their left temporoparietal cortex, a region of the brain known to be involved in speech perception, for two weeks. The team assessed them using the Tinnitus Handicap Inventory, self-ratings of symptoms and audiometric measures of residual inhibition. The researchers found, before and after treatment during the next four months, no signifi- cant differences in basal measures or responses to different frequencies of rTMS among the four groups. Responses depended on tinnitus duration: those participants who had tinnitus for the longest period of time responded least to treatment. The investigators concluded that daily sessions of rTMS over the temporoparietal cortex may be a potentially useful tinnitus treatment. Heidelberg Model of Evidence-Based Music Therapy4 Germany, July 2008 More than a half-million patients in Germany who need tinnitus treatment suffer from tonal tinnitus (tinnitus with a well-defined frequency). Heike Argstatter, Ph.D., and her research team held the opinion that though tinnitus is one of the most common symptoms in ear, nose and throat (ENT) medicine, its treatments are polypragmatic and often lack scientific foundation. They developed a novel music therapy and substantiated it with psychological, audiological and functional imaging procedures. They believe the advantages of this therapy are the integration of known and well proven acoustic and psychotherapeutic techniques converted to resonance training, neuroauditive cortex reprogramming and tinnitus desensitization. The team found the music therapy an effective treatment for 190 patients with chronic tonal tinnitus and highly advantageous to treatment duration, effectiveness and follow-up stability compared with customary interventions. Brain imaging strongly suggests the usefulness of further investigation and discussion of neuronal tinnitus modeling. Acute High-Intensity Sound Exposure Alters Responses of Place Cells in Hippocampus5 United States, March 2009 Overstimulation is known to activate neural plastic- ity (the brain’s ability to adapt to new conditions) in the auditory nervous system causing changes in function and re-organization in brain systems. Previous research demonstrated that overstimula- tion, using high-intensity noise or tones, can induce signs of tinnitus. Here, Timothy J. Goble, Ph.D., and his team utilized rat studies to show that over- stimulation causes changes in the way a subset of hippocampal pyramidal neurons (place cells) respond as rats search for rewards in a spatial maze. In familiar environments, place cells respond when the animal moves through specific locations but are relatively silent in others. This location-specific fir- ing is stable in a fixed environment. The team assessed rats with four implanted micro- electrodes for stable single-unit place-field responses. They compared rats exposed for 30 minutes to a 4 kHz tone at 104 dB sound pressure level (SPL) to a control period in the same sound chamber. Their work demonstrated that activation of neural continued on page 22
  • 14. 14 Tinnitus Today | August 2009 A Walk in the Park and Across America The First Annual American Tinnitus Association Walk For A Cure 14 Tinnitus Today | April 2009 Setting Up Saturday, May 16, 2009, Irvine Regional Park, Orange County, Calif. The perfect day and location for the first annual ATA Walk For A Cure. At 6:30 a.m., on this beautiful spring morning, volun- teer event chair Mari Quigley-Miller and several of her Walk com- mittee members transported tables, chairs and water to the park. Other event volunteers put up directional signs throughout the park, clearly marking the way to the designated Walk area. Spirits were high as more volunteers arrived to set up the registration area, hang banners and stock the water stations. Excitement continued to build as event walkers began arriving around 8 a.m. – many accompanied by their children and ener- getic dogs on leashes – with great enthusiasm for this unified effort to support ATA and the fight to cure tinnitus. Warming up At 9:00 a.m., Lindy Michaelis, daughter of entertainer Pat Boone, led the group in stretching exercises. With show business in her blood, she turned what some consider the mundane part of exer- cising into something lively and fun. After the warm-up, Terri Baltus, past ATA chief development offi- cer, delivered a message on behalf of ATA to an attentive crowd of around 150 walkers. She thanked everyone for their support and emphasized that as a group we can accomplish what no one per- son can do alone. She defined the Walk as the center of a cross- country, virtual movement that is reaching out into communities across America. Terri then introduced ATA-funded research scientist, Fan-Gang Zen, Ph.D., who was at the Walk with his young daughter, her friend and a few graduate students from his program at the University of California, Irvine (UCI). Zeng’s presence was a “The walk was wonderful. It was the first walk I’ve ever been on and it felt so good to be in allegiance with everyone there.” ~ Normajean Brady Walk participant & ATA Member
  • 15. 15August 2009 | Tinnitus Today Thank you to everyone who contributed to the Walk For A Cure. Thanks to Walk donations by hundreds of supporters, ATA raised $58,379 through the combined efforts of the walkers in Orange County, the virtual walkers and a direct mailing to our membership. powerful example of how the money ATA receives from its members and supporters is helping to fund excellent research. Mari then sang a lovely rendition of our National Anthem, a fitting introduction to a local treasure, Sammy Lee, M.D. Accomplishing an important dream, Lee received back-to- back gold medals in diving in the 1948 Olympics in London, followed by his 1952 triumph at the Helsinki games. He went on to become a respected ear, nose and throat (ENT) physician in Orange County. Lee, now retired, truly understands the problem of tinnitus and supports ATA’s mission. A Walk in the Park Mari, accompanied by her dogs, Sonny and Cher, led off the mile and a half walk through Irvine Regional Park. Event organizer Mari Quigley-Miller (second from right) and several Walk committee members. Complimentary Walks At the same time the Orange County participants were walking in the park, Donna Brown’s team, “Donna’s Daytrekkers,” held their own mini- walk in Denver, Colo. at Van Bibber Park. Nine team members, including local tinnitus support group leader Rich Marr, joined Donna, who climbed Mt. Rainier in support of ATA in July 2007. We’d like to hear about anyone else who may have con- ducted their own mini-walk in support of ATA. Please send details to Nina Rogozen, Editor, Tinnitus Today, at nina@ata.org. Stay tuned this coming winter for details on ATA’s Second Annual Walk For A Cure, taking place in Portland, Ore. in the spring of 2010. 15August 2009 | Tinnitus Today continued on page 16
  • 16. 16 Tinnitus Today | August 2009 The group of spirited, eager walkers ambled along a peaceful creek, through lush foliage and then circled back to where the event began. Volunteers handed out goody bags containing several small, locally donated items, such as power bars, earplugs and refrigerator magnets. After the Walk, people hung around to enjoy a sense of camaraderie and the satisfaction of a mission fulfilled. Groups clustered to share conversations with each other, Zeng, Lee, Mari and the Walk committee. One could hear enthusias- tic Chinese, Spanish and English voices, a reflection of the diverse makeup of the Walk committee and the walkers they recruited. In addition to conventional local outlets, tinnitus stories in one Spanish and two Chinese language newspapers also covered the Walk. A Walk in the Park and Across America Many Virtual Walkers Participated In conjunction with the Orange County Walk, hundreds of supporters from across America – and a few beyond our borders – participated in spirit, signing up at the ATA Web site as fundraising team members and Walk supporters. We displayed the names of the hundreds of virtual walkers at the Walk site itself; you can view them by going to www.ata.org/walk-for-a-cure-list. continued from page 15 Words About the Walk Two young men, Jeff Dennison and Michael Conti, who both suffer with tinnitus, ran the entire Walk course. Their rationale for running at a walk? “We’re running so we can get to a cure faster!” Supporters from Cal National Bank For the second consecutive year, tinnitus is ranked as the number-one service-connected disability for U.S. military personnel returning from the conflicts in Iraq and Afghanistan. The chart on the left shows the most common disabilities for returning personnel as of October 2007. The Incidence of Tinnitus in U.S. Veterans Continues to Escalate Most common service-connected disabilities for Iraq & Afghanistan veterans as of October 2007 Iraq & Afghanistan veterans service-connected disability rates for tinnitus and hearing loss as of October 2008 27% 24% 2007 2008 100,000 90,000 80,000 70,000 60,000 50,000 40,000 30,000 20,000 10,000 0 Information courtesy of VA Office of Public Affairs. 22% 14% 13% Tinnitus – 27% Lumbosacral or Cervical Strain – 24% Defective Hearing – 22% Post Traumatic Stress Disorder (PTSD) – 14% Limitation in Flexion of Leg – 13% TINNITUS HEARING LOSS TINNITUS HEARING LOSS The chart on the right illustrates the sharp increase in service-connected disability payments to Iraq and Afghanistan veterans for tinnitus from 2007- 2008. The incidence of tinnitus increased more dramatically than did hearing loss. This is an indicator that other medical conditions, like the demonstrated link between tinnitus and traumatic brain injury, may be contributing to the pointed increases in tinnitus among veterans.
  • 17. 17August 2009 | Tinnitus Today Q: How did you decide to participate in the study? A: I found out through ATA that Dr. Piccirillo was conducting a new rTMS trial at Washington University in St. Louis. Because of the promising research reports I have read about the treatment, I decided that I would explore whether or not I was a viable candidate. I had an initial consultation [pre-screening] in September 2008 where the study team also explained the possible side effects. They told me I was a good candidate for the study. ATA Member Participates in Tinnitus Clinical Trial: A Q&A with Mark W. Church About rTMS An interview conducted by Daniel Born, ATA Director of Research & Special Projects and Jennifer DuPriest, ATA Associate Executive Director Background Interviewee: March W. Church from St. Louis, Mo., is a six-year ATA member and CEO of Application Engineering Group (AEG), an ATA corporate member. Mark is 48 years old and has had tinnitus for 10 years. He describes his bilateral tinnitus (in both ears) as “wildly fluctuat- ing tinnitus.” Topic of study: A two-year, double-blind study of Repetitive Transcranial Magnetic Stimulation (rTMS), including 60 participants, led by Jay F. Piccirillo, M.D., F.A.C.S., at Washington University in St. Louis, Mo. Goal of study: To determine if applying rTMS to the hearing area of the brain can lessen the perception of tinnitus. rTMS involves placing a strong magnet against a person’s scalp to generate a small electrical field within the brain. Depending on stimulation frequency, this electrical field can either decrease or increase the electrical excitability of the brain. This study uses low- frequency stimulation since it is thought to decrease nerve activity. It is this electrical excitability of the brain that is thought to cause tinnitus.1 Hypothesis of study: rTMS can decrease the perception of tinnitus. Participants will initially receive either active rTMS or placebo rTMS for two weeks, then rest for two weeks. Next, they will receive the treatment they did not receive in the first two weeks. Treatments will be randomly administered and participants will not be told which they are receiving. Each will undergo magnetic resonance imaging (MRI) and positive emission tomography (PET) scanning of the brain at the beginning of the study and after each treatment.2 Q: Did you undergo any testing before you started treatment? A: After the initial screening, the study team administered the Tinnitus Severity Index to determine my specific tinnitus level. My particular type of tinnitus is pretty bad; it occurs in both ears and fluctuates wildly. The next day they performed an MRI and PET scan and mapped my brain activity. Q: What was rTMS treatment like? A: The rTMS device was placed above my left ear and pulsed at half-second intervals for 20 minutes. There were 10 consecu- tive treatments, Monday through Friday, with a two-day week- end break. A two-week rest period took place and then rTMS was resumed for 10 additional treatments. Memory tests were administered after every treatment to make sure I was not having adverse side effects. It was a double-blind study but I could definitely tell the difference between real treatment and a placebo treatment. With the real treatment, the left side of my body jumped like during a knee reflex test. continued on page 18 What is rTMS? Repetitive Transcranial Magnetic Stimulation (rTMS) is a pro- cedure that uses a pulsed magnetic field to influence electrical activity in the brain. The effects of magnetic fields on humans were considered as early as the 18th century by Franz Anton Mesmer, a German physician and astrologist. However, it was not until the end of the 19th century that scientists started using magnetic energy to alter brain activity.3 Interview with Mark Church
  • 18. 18 Tinnitus Today | August 2009 Over the past two years, ATA has enjoyed some major advocacy accomplishments. The Department of Defense (DoD) now supports tinnitus research through its Peer Reviewed Medical Research Program (PRMRP) for the first time since the program’s inception.There is now successful inclusion of directive com- mittee report language that has accompanied the Labor Health and Human Services bill for the past three years. This language encourages the National Institutes of Health (NIH), the DoD and the Department of Veterans Affairs (VA) to come together to collaboratively address tinnitus from a multi-disciplinary approach. The result is a tinnitus-specific workshop hosted by the National Institute on Deafness and other Communication Disorders (NIDCD) regarding “Brain Stimulation for the Treatment of Tinnitus,” being held Aug. 13-14, 2009 on the NIH Campus. And lastly, the establishment of a DoD Center of Excellence on auditory systems injury for our military and veterans, who experience tinnitus dispropor- tionate in numbers, and often in severity, to the rest of the population. We are Grateful for Congressional Support ATA and the rest of the tinnitus community owe a debt of gratitude to the elected officials who helped make these initiatives become reality. Because of their work, ATA chose to honor two outstanding Senators whose leadership and support of ATA’s mission to cure tinnitus made these accomplish- ments possible. Q: What sorts of safety precautions were in place? A: The team did a hearing test [audiogram] at three different intervals to ensure no damage to my hearing center was taking place. There were constant questionnaires and memory tests, plus three psycho- logical exams to test for possible cognitive changes. Q: Did you have any concerns about the process? A: The MRI machine was very loud and physically uncomfortable. It is difficult to lie still for such a long period of time. I had to mentally psyche myself into getting through it as I am somewhat claustro- phobic. It was also time consuming; I spent two hours each day having rTMS treatment. Then I had six hours of PET and MRI scans and other tests. Q: Did you experience any side effects? A: Besides my left side jumping uncontrollably during the treatment, no. I was told that some people experience headaches, but I felt fine. Q: Did the treatment work? A: rTMS was not effective for me - but I want to do my part and help get us closer to a tinnitus cure. Q: Would you participate in another tinnitus treatment study? A: Dr. Piccirillo is a class act, and his team was very professional. I am open to taking part in other aspects of his tinnitus treatment research. In fact, he has a second part of the rTMS study that I will be participating in and will let you know how it goes. A Q&A with Mark W. Church About rTMS continued from page 17 1 http://clinicaltrials.gov/ct2/show/NCT00567892?term=tinnitus&rank=19. 2 Ibid. 3 http://www.bnl.gov/medical/tms/history.asp. 18 Tinnitus Today | August 2009 It was a double-blind study but I could definitely tell the difference between the real treatment and a pla- cebo treatment. With the real treatment, the left side of my body jumped like during a knee reflex test. rTMS was not effective for me – but I want to do my part and help get us closer to a cure. ~ Mark Church Honoring New Friends in Our Nation’s Capital By Jennifer DuPriest, ATA Associate Executive Director
  • 19. 19August 2009 | Tinnitus Today On May 12-13, 2009, Scott C. Mitchell, J.D., recent past chair, ATA Board of Directors, board members John Bates and Michael O’Rourke, ATA government relations counsel Deborah Outlaw and I visited the offices of Senator John Cornyn (R-TX) and Senator Harry Reid (D-NV) to thank them personally for their support and to honor them for their essential actions toward curing tinnitus. Senator Cornyn has always been deeply committed to serving America’s veterans. Because of ATA’s education of the Senator and his staff about the growing incidence Conversations with a Senator: Scott C. Mitchell, J.D., John R. Bates, Jennifer DuPriest and Senator John Cornyn (R-TX) in his Washington, D.C. office. A T A A D V O C A C Y I N A C T I O N of tinnitus in active duty military and veterans, he supported the creation of the DoD Center of Excellence on auditory systems injury, included in the final 2009 DoD Authorization Bill. This center will not only pro- vide critical care to members of the military who suffer with tinnitus, but will provide educational materials and conduct ongoing research on its patient popula- tion. These efforts will help continue to inform the tinnitus research community about a certain kind of tinnitus and help us all get closer to our collective goal of silence. Senator Reid is also deeply committed to serving America’s veterans and understands the importance of funding biomedical research for all who suffer from this condition. Again, ATA’s education of congressional members about this often overlooked condition resulted in Senator Reid’s gracious support of the inclusion of tinnitus as a researchable condition in the PRMRP. We look forward to continued work with both Senators Reid and Cornyn and all the other members of Congress who are helping ATA pave the way to a cure! 19August 2009 | Tinnitus Today
  • 20. 20 Tinnitus Today | August 2009 In this ATA-funded study, we examined the properties of DCN neurons seven days after intense sound exposure and compared them to normal neurons. Families of special- ized proteins called “ion chan- nels” are located in neuronal membranes and selectively allow ions (charged atoms, such as sodium, potassium and chloride) to move in or out of the cell. This movement depends on the voltage across the neuron’s membrane and the difference in the concen- tration of ions between inside and outside the cell. Opening ion channels changes the voltage across the cells’ membranes. Opening and closing of specific types of ion channels produces action potentials (Fig. 1), which are the means by which neurons send infor- mation to other neurons. Other ion channels control the pattern or time between action potentials. We have found a marked change in membrane properties in DCN neurons following intense sound exposure. The changes are consistent with an over- all increase in the opening of ion channels at rest. In addition, after intense sound exposure, there is an increase in DCN neurons firing two action potentials (couplets) in rapid suc- cession. We also observed this firing pattern in our recent study, using recordings from outside cells; we directly observed the underlying membrane potential changes associated with firing in couplets. Future Work Future characterizations of the ion channel changes produc- ing these membrane potential changes, and the increase in open channels (measured as increased conductivity) following intense sound exposure, may demonstrate changes that are important in the generation of tinnitus. Changes in ion channels have also been found to be important in the change in neuronal activity asso- ciated with phantom pain, a con- dition similar to tinnitus. Studies on phantom pain provide impor- tant examples of changes that should be examined in tinnitus. In conclusion, this study provides the groundwork for identifying and understanding specific ion channels, which may be altered in tinnitus. This information could lead to targeted treatments for tinnitus. Paul G. Finlayson, Ph.D., is Assistant Professor of Otolaryngology and Ophthalmology for the Wayne State University School of Medicine in Detroit, Mich. He was recently named interim scientific director of the Ligon Research Center of Vision at Kresge Eye Institute, also in Detroit. Tinnitus and Hyperactivity in Dorsal Cochlear Nucleus Fusiform Cells: What Biophysical Changes Occur in These Cells Paul G. Finlayson, Ph.D., Wayne State University, Detroit, Mich. An effective tinnitus treatment may depend on our understanding of the alterations in the brain and in the cells/neurons which produce these phantom sound sensations. Animal models have shown that intense sound exposure increases spontaneous “firing activity” (action potentials) in neurons, such as in one of the first brain auditory centers, the dorsal cochlear nucleus (DCN). Action potentials are the major way neurons communicate information, such as sound, and an increase in their rate could produce the phantom sounds of tinnitus. Figure 1. Dorsal Cochlear Nucleus cells were more likely to produce action potentials in couplets. This rapid pattern of activity is more likely to be perceived as sound by other areas of the brain. (“milli” = 1/one thousand; 1/1000). Paul G. Finlayson, Ph.D.
  • 21. 21August 2009 | Tinnitus Today Medical treatments for tinnitus have historically been difficult to evaluate. This is due to the extremely complex nature of tinnitus, diversity of tinnitus causes and lack of understanding about underlying mechanisms. Limited measurement tools and the challenges in the lives of those who suffer from tinnitus contribute to evaluation difficulties. The American Tinnitus Association is co-funding a clinical trial of a medication called acamprosate (brand name, Campral®) at the Oregon Health & Science University (OHSU) in Portland, Ore. Acamprosate was developed to help recovering alcoholics abstain from drinking by modifying the balance between excitatory (when nerves activate other nerves) and inhibitory (when nerves prevent others from activating) chemicals produced by the brain. It is possible that an imbalance in the hearing centers of the brain (not related to alcoholism) may be one cause of tinnitus. A pilot study in Brazil suggested that acamprosate might be helpful for some types of tinnitus.1 Bringing Participants on Board The three-year OHSU study began in January 2008 and has been a massive endeavor. So far we have processed over 2,000 contacts from tinnitus suffer- ers interested in being in the study. Of those, 596 individuals went through screening evaluations and 234 have met the very strict inclusion criteria to par- ticipate in the study. Most of those have enrolled in Phase I of the trial. Phases I, II and III Phase I is an open-label trial (both the researchers and participants know the identity of the treatment) during which all participants take acamprosate for six weeks. Those who respond positively to the medication may continue into an extended Phase II of the study. We release from the study those who did not have a positive response to the acamprosate in Phase I or asked to be released for other reasons, such as side effects, logistics or time constraints. During this second phase, everyone receives acam- prosate for part of the time and a placebo for part of the time, without knowing which they are taking at any given time. This experimental design is very important because it recognizes that no treatment should be expected to work for everyone with tinni- tus. It separates non-responders from potential true responders early in the study and allows us to focus resources and research efforts on those most likely Clinical Trial of Acamprosate for Tinnitus William Hal Martin, Ph.D., and Yong-Bing Shi, M.D., Ph.D., Oregon Hearing Research Center, Oregon Health & Science University to benefit from the treatment. We are continuing to enroll participants in Phase I and hope to enroll about 300 people in all. We have begun Phase II as well. During Phase III of the study, we will look back at those who did and did not respond positively to acamprosate. (This can include a decrease in the per- ceived loudness of their tinnitus, or an improvement in their overall quality of life.) During this review process, we identify factors (tinnitus pitch, loudness, duration, other medical issues, etc.) about those groups that will help us predict who should or should not benefit from acamprosate treatment. We believe that this will help us understand the role of the brain in tinnitus and help us develop more effective treatments in the future. Recognition for Innovative Design The tinnitus research community recognizes this study for its importance on three levels. First, every- one is interested in knowing if medications like acamprosate can be helpful to those with tinnitus. Second, we are all interested in the role of the brain in tinnitus and this experiment allows us to change brain chemistry in a very interesting way. Finally, and perhaps most importantly, this is the first time anyone has applied this type of strict experimental design to studying interventions for tinnitus. The design may prove to be the standard by which the research com- munity evaluates all future medical therapies. William Hal Martin, Ph.D., is Professor of Otolaryngology/Head and Neck Surgery and Professor of Public Health & Preventive Medicine at the Oregon Health & Science University in Portland, Ore. He directs four programs within the Oregon Hearing Research Center: the OHSU Tinnitus Clinic, Tinnitus Research Program, Intraoperative Neurophysiological Monitoring Services and Dangerous Decibels® Noise Jennifer Petersen, Au.D., OHSU Senior Tinnitus Specialist, Yong-Bing Shi, M.D., Ph.D., and William H. Martin, Ph.D. continued on page 25
  • 22. 22 Tinnitus Today | August 2009 plasticity through overstimulation of sound can alter the response of these hippocampus place cells. Tinnitus in Young Patients Up to 35 Years Old6 Poland, 2008 Tinnitus can occur even in the young. According to the work of Danuta Raj-Koziak, M.D., and her team in Poland, it is becoming more common in young people. They found that about 25% of patients registered in their tinnitus clinic are below the age of 35. Their study evaluated a group of 235 tinnitus patients ranging in age from 18 to 35 years old. There were no other pre-selection criteria except age. All participants answered questions concerning the cause of their tinnitus. Their findings indicate that the most frequent tinnitus triggers among patients below 35 years are infections (68.5%), noise exposure (27.7%) and stress (23.4%). Tinnitus Treatment: Neurosurgical Management7 France, March 2009 Tinnitus management requires a multidisciplinary approach in which neuromodulation and neurosur- gery tend to play major roles. One classification of tinnitus is objective tinnitus (sounds in the ear that can be heard by someone besides the person with tinnitus). One form is pulsatile tinnitus, synchronous with one’s heartbeat. Radiological testing should search for a vascular abnormality as well as other neurological diseases (intracranial hypertension, Arnold-Chiari malformation, vascular loops, etc.). Asynchronous objective tinnitus generally corre- sponds to muscular contractions requiring specific management. The other classification is subjective tinnitus (perceived only by the patient), which is more complex and strongly analogous with post-amputation pain syndromes. After peripheral middle ear or inner ear damage, auditory deafferen- tation (freeing of sen- sory nerve fibers) could result in hyperactivity and/ or functional reorganization within central auditory and nonauditory structures of the brain. According to Alain Londero, M.D., and his colleagues, this could explain the persistence of tinnitus after sever- ing the 8th auditory nerve, and associated symptoms such as hyperacusis or anxiety and depression. This model finds strong support in animal experiments and in functional neuroimagery (PET, fMRI, MEG). Without etiologically-based therapies available, severe, subjective tinnitus management only targets tinnitus tolerance with sound enrichment or cognitive behavior therapy. Soon, better knowledge of tinnitus pathophysiology and innovative therapeutic tools could emerge from neuromodulation techniques, such as repeated transcranial magnetic or epidural electric stimulation. Educational Counseling Used in Progressive Audiologic Tinnitus Management8 United States, January-March, 2009 Exposure to loud sounds commonly causes or exacerbates tinnitus. The National Center for Rehabilitative Auditory Research conducted clinical research, led by James A. Henry, Ph.D., which resulted in a clinical model of tinnitus management: Progressive Audiologic Tinnitus Management (PATM). It involves five levels of management: triage, audiologic evaluation, group education, tinnitus evaluation and individualized management. A key part of PATM is counseling by audiologists and, as needed, mental health providers. Rather than focusing on didactic, informational counseling, it facilitates patients’ learning to better adjust to the disturbing auditory realities of tinnitus. It employs tools from two powerful skills sets advantageous to the self-management of chronic tinnitus: the use of therapeutic sound and cognitive-behavioral psychology techniques. 1 Cacace A. Tinnitus Research: Tales From a Grand Meeting at Grand Island, N.Y, Am J Audiol. 2008 Dec;17(2):107. 2 Tyler R, Coelho C, Tao P, Ji H, Noble W, Gehringer A, Gogel S. Identifying tinnitus sub- groups with cluster analysis, Am J Audiol. 2008 Dec;17(2):S176-84. 3 Khedr EM, Rothwell JC, Ahmed MA, El-Atar A. Effect of daily repetitive transcranial magnetic stimulation for treatment of tinnitus: comparison of different stimulus frequen- cies. JNNP. 2008;79:212-215. 4 Argstatter H, Crick C, Belay HV. Music therapy in chronic tonal tinnitus. Heidelberg model of evidence-based music therapy. HNO. 2008;56:678-685. 5 Goble TJ, Møller AR, Thompson LT. Acute high-intensity sound exposure alters responses of place cells in Hippocampus. Hear Res. 2009 Mar 18. [Epub ahead of print]). continued from page 13 Highlights: Selected 2008-2009 Tinnitus
  • 23. 23August 2009 | Tinnitus Today The following definitions will assist you in reading “Highlights: Selected Tinnitus Research Studies in 2008-2009” (beginning on page 12), which describes some of the notable tinnitus research results from around the world. Audiogram: a graphic representation of the relation of vibration frequency that shows the softest sounds a person can hear at different pitches or frequencies. Auditory deafferentation: elimination or interruption of sensory nerve impulses by destroying or injuring the sensory nerve fibers. Basal measures: measurements of vital organism activities, such as heartbeat and respiration. Bilateral tinnitus: affecting both the right and left ears. Cross-sectional survey: a study in which a statistically signifi- cant sample of a population is used to estimate the relationship between the results of the study and the various characteristics of the population studied at a certain point in time. Dorsal Cochlear Nucleus (DCN): a cortex-like structure on the dorso-lateral surface of the brainstem where auditory nerve fibers from the ear’s cochlea form their first synapses. Epidural region: the outermost part of the spinal canal. Epidural electric stimulation: treatment involving implanted electrodes in the epidural region of the body. Etiology: the cause or causes of a disease or abnormal condition; a branch of medical science dealing with the causes and origins of diseases. Hippocampus: an area deep in the forebrain that helps regulate emotion and memory. Hippocampal pyramidal neurons: multipolar sensory neurons located in the hippocampus region of the brain. Hyperacusis: over-sensitivity to some frequency ranges of sound. Intracranial hypertension: a condition where the cerebrospinal fluid (CSF) inside the skull reaches elevated levels. Multidisciplinary approach: composed of or combining several usually separate branches of learning or fields of expertise, specialized subjects or skills. Neuroauditive cortex: the region of the brain responsible for processing auditory (sound) information. Neuroauditive cortex reprogramming: a therapy utilizing sound to reduce the perception of tinnitus. Neural plasticity: the ability of neural circuits to undergo changes in function or organization. Neuroimagery: various techniques (PET, fMRI and MEG) used to either directly or indirectly image the structure and function of the brain. Neurons: excitable cells in the nervous system that process and transmit information by electrochemical signaling. Objective tinnitus: head or ear noises audible to other people as well as the patient. Occipital: of, relating to or located within or near the occiput (back of the head) or the occipital bone. Psychoacoustics: a branch of science dealing with subjective human perceptions of sounds. Sham: a treatment, e.g., medication or procedure, used in a scientific study as a control, usually omitting some or all key therapeutic ele- ments of the treatment being studied; commonly called a “placebo.” Somatic modulation: movement of the jaw, head or neck that causes the loudness and/or frequency of one’s tinnitus to fluctuate. Somatosensory: of, relating to, or being sensory activity with an origin elsewhere than in the special sense organs, e.g., eyes and ears, and conveying information about the state of the body proper and its immediate exterior environment. Subjective tinnitus: head or ear noises audible only to the sufferer. Synaptic plasticity: the ability of the synapse (connection) between two neurons to change in strength. Temporoparietal cortex: a region of the brain known to be involved in speech perception. Tinnitus Handicap Inventory: a self-reported test utilized to assess a person’s tinnitus-related handicap and to report treatment outcomes. Tonal tinnitus: a continuous sound with a well-defined frequency; heard as ringing, buzzing, chirping. Vestibulocochlear nerve: a sensory nerve responsible for transmit- ting sound and equilibrium information from the inner ear to the brain; also known as the 8th nerve. Tinnitus pathophysiology: the study of the changes of normal mechanical, physical and biochemical functions affected by tinnitus. Research Studies 6 Raj-Koziak D, Bartnik G, Skarzynski H, Pilka A, Fabijanska A, Borawska B., Tinnitus in young patients up to 35 years old. Otolaryngologia Polska. 2008;62:476-479. 7 Londero A, Chays A. Tinnitus treatment: neurosurgical management. Neurochirurgie 2009 Apr;55(2):248-258. Epub 2009 Mar 20. 8 Henry JA, Zaugg TL, Myers PJ, Kendall CJ, Turbin MB. Principles and application of edu- cational counseling used in progressive audiologic tinnitus management. Noise Health. 2009 Jan-Mar;11(42):33-48. Glossary of Research Terms
  • 24. 24 Tinnitus Today | August 2009 Questions and Answers Notice: Please feel free to call Dr. Vernon any Friday, 9 a.m. to noon and 1 to 5 p.m. Pacific Time at (503) 494-2187 (please do not leave messages). You can also e-mail your questions to Nina Rogozen, Editor, at nina@ata.org or mail them to Tinnitus Today, American Tinnitus Association, P.O. Box 5, Portland, OR 97207-0005. Jack A.Vernon, Ph.D. QMy tinnitus (mild nonstop ringing in both ears) started in 1990 and was caused by extreme stress and worry when I received some very bad news. My theory is that this stress released chemicals in my body, including in my brain. I would like to know if stress has caused tinnitus for any other readers. A Stress causes the human body to release stress hormones, which stimulate its ability to escape or conquer the stressful situation. They target specific organs of the body and generally have an immediate effect. Many parts of the body can be affected by stress. The heart and cardio-vascular system are good exam- ples of places adversely affected by stress, such as heart attacks and high blood pressure. Individuals vary con- siderably in their psychological reactions to stress, which also depend on the origin of the stress and their ability to handle it. But one thing is pretty certain: all stress – physical, psychological, emotional or spiritual – results in physiological responses. It is difficult to say whether the stress was the primary cause of your tinnitus. QI sometimes experience a ticking sound in my right ear. Recently when this happened, I simultaneously felt tightness and pulsing in the area from the underside of my chin toward my neck (right side). It was more noticeable when I was lying on my back. It lasted for a few weeks and is now gone. Have you ever heard of this and is it possible that there is a muscle, tendon or ligament that is pulsing with the ticking? Regarding your temporary ticking sounds, these and similar types of mechanically-originating sounds are not uncommon. And tinnitus is often accompanied by a sensation of pressure. Sometimes a Eustachian tube dysfunction appears to cause the problem. Also, we now know that tinnitus in some people may change when they move their jaw or neck or press on the mus- cles of the head. Those clicking sounds that you heard, and the sensation of pressure, may have been caused by spastic behavior of the complex muscles of the head or neck. It is possible that they are indicative of some temporary abnormality of your temporomandibular joint on one side. If you experience such feelings again, you may be clenching your teeth, tightening your jaw or grinding your teeth while sleeping. If it becomes too QI am an ATA member and here is my ques- tion. In the history of medicine, has there ever been a case where tinnitus has stopped, gone away and left the victim alone? If so, I figure that there is still hope; and since it happened to someone else, it could happen to me. If not, I will continue to live with it and hope they find a cure during my lifetime. That’s my question du jour. Thanks for your help. AYes, tinnitus can disappear on its own, but this is rare and we don’t know the conditions that cause it to do so. Sometimes the disappearance seemed to be related to the use of masking. Other times it just spontaneously went away, however that is very uncommon. You don’t have to wait around hoping for a sponta- neous disappearance. There are things you can do to help yourself, such as masking – using a variety of sounds to block the tinnitus, such as ambient noise, TV or radio, fountains. Some people find relief with Xanax® (alprazolam, an anti-anxiety drug) and some utilize methods of counseling that help them better manage their tinnitus.
  • 25. 25August 2009 | Tinnitus Today annoying, your dentist could refer you to someone who can provide you with a temporary “fix” – a plastic insert to wear in your mouth at night that prevents teeth grinding. QI hear a lot of comments about a cure for tinnitus but I do not hear any comments as to how such a cure might be found. In your opinion, is a cure a realistic possibility, and if so, how will it come about? A Yes, I think a cure is possible, at least for certain kinds of tinnitus. As you well know, as hearing declines, tinnitus increases; it’s something of a see-saw effect. Now given that dynamic, if we can improve hearing it is my guess that tinnitus will decrease. How do we increase hearing? Hopefully we’ll do it with stem cells. We can harvest these versatile cells from the person’s own nasopharynx (uppermost part of the pharynx, extending from the base of the skull to the upper surface of the soft palate) so that there is no or little chance for rejection. In my opinion, work with stem cells has the possibility of enhancing recovery from all manner of health problems. “Visiting your Houston clinic was the best thing I ever did.” – Lupe G. “You gave me my life back.” – Allan W. Migraine-Meniere-Tinnitus Clinic We identify and treat the causes and triggers of tinnitus Soraya Hoover, M.D., Medical Director At the Migraine-Meniere-Tinnitus Clinic, we focus our diagnosis & treatment on the patient’s physiological, pathological and anatomical malfunctions of their nose, sinuses and Eustachian tubes. Treatment corrections aim to normalize functions and equalize the nasal airway. This may take three to 10 days. We accept most Medical insurance plans. Please call for more information. Dr. Hoover is a Fellow of the American Academy of Otolaryngology, Board of Allergy & Environmental Medicine and Royal Society of Medicine, London, and a Diplomat of the Royal College of Surgeons of England. Dr. Hoover has served the Houston area for 25 years, spoken in over 26 countries and published in numerous medical journals, such as: – International Rhinology. Supplement 2.all.1987 – Tinnitus & Allergy. Proc II International Tinnitus Seminar, Munster, Germany. 1987. Publisher, Harch V. Karlstruhe – The Journal of Japan Rhinologic Society. Vol 30,1(1991) Shepherd Exit – 5151 Katy Freeway, Suite 300, Houston, TX 77002 Call (713) 626-4999 to make an appointment www.tinnitus-menieresclinic.com/index.htm http://www.headache-migraineclinic.com ATA does not endorse or recommend any tinnitus products or treatments. Advertisement delicate cilia (ear hair cells) leading to SNHL, tinnitus and hyperacusis. Treatment for REKS has not yet been successful, but prevention is a must. A light kiss to a child’s ear produces a surprisingly rapid and intense ear canal vacuum.5 An infant cannot say, “Mommy, I can’t hear now.” Let us avoid preventable tragedies like this. Kiss, and kiss away, but please avoid that ear canal. Dr. Levi A. Reiter is Professor of Audiology and the audiology program head at Hofstra University’s Department of Speech-Language-Hearing Sciences. He teaches courses in diagnostic audiology, anato- my and physiology, psychoacoustics, deafness and electrophysiology. He is also on the faculty of the Long Island Audiology Consortium and maintains an active audiology practice in Brooklyn, N.Y. The grandfather of 20 is a published rapper and enjoys promoting the audiology profession with songs like, “Say Whut?” 1 Reiter, L.A. The kiss of deaf. The Hearing Journal. 2008 Aug;61(8):32-37. 2 Reiter, L.A. Pathologic sequelae of ear-kissing. Abstracts of the Meeting of the Association for Research in Otolaryngology. 2009 Feb;604. 3 Reiter, 2008. 4 Smaka, C. The kiss that caused hearing loss, or Reiter’s Ear-Kiss Syndrome (REKS). Audiologyonline. 2008 July 28. 5 Reiter, 2009. Can a Simple Kiss on the Ear Cause Auditory Problems? continued from page 11 Clinical Trial of Acamprosate for Tinnitus continued from page 21 Induced Hearing Loss and Tinnitus Prevention Program. Martin also serves as the Research Scientist in Residence at the Oregon Museum of Science and Industry (OMSI) in Portland. Yong-Bing Shi, M.D., Ph.D., is Assistant Professor of Otolaryngology/Head and Neck Surgery at the Oregon Health & Science University. He examines and treats patients with tinnitus and hearing problems, as well as voice and swallowing disorders. He also serves as the medical director of the OHSU Tinnitus Clinic and the Northwest Center for Voice and Swallowing. In addition, Shi monitors brain, nerve and spinal cord function during surgical procedures in which those structures may be injured by the procedure. 1 http://www.ncbi.nlm.nih.gov/pubmed/15000513.
  • 26. 26 Tinnitus Today | August 2009 Corporate Champions $5,000+ AEG is a comprehensive business solution company that provides information technology (IT) services to companies and organiza- tions throughout the U.S.   Leadership Donors $100,000+ Marianna Dennis Sustaining Donors $1,000 to 4,999 Anonymous (2) Dennis W. Anderson Bryan Richard Aubie Sandra E. Baan Joseph F. and Frances A. Bachman, M.D. John R. Bates Anthony T. Cacace, Ph.D. Stephen and Jennifer Sue Chandler of the Scottsdale Foundation Neil Cherian, M.D. Roland D. DeCastro Jeffrey A. Ferenz Foreningen Lydhoer Ronald K. and Donna Mae Granger Richard E. Haney, Ph.D. John Horst, Famous Tate Electric Company Jim and Angela Hsu William H. Hurt Mrs. Leonard E. Johns Mark K. Johnson, J.D. Arthur F. Kuckes and Martha A. Wright Fund of the Tompkins Charitable Gift Fund John Malcolm Robert B. Maloney Bruce F. Martin Steve Martin Charitable Foundation Mary B. Meikle, Ph.D. Microsoft Gary P. Reul, Ed.D. Stephen M. Schwarcz, D.D.S. and Wendy J. McPherson Jerry Shannon Jack A. Vernon Ph.D. and Mary B. Meikle, Ph.D. John L. Zabriskie and Adelaide W. Zabriskie Fund Special Donors and Tributes Thank you to all of our donors. Your generosity and commitment make possible ATA’s continuing effort to support innovative tinnitus research – investigations that are searching for improved tinnitus treatments, and eventually a cure.We greatly appreciate each and every ATA member.Without you, there would not be an American Tinnitus Association. We’d like to provide you with even more information on tinnitus on the pages of Tinnitus Today. Therefore, beginning with this issue, Supporting Donors ($100-499) will now be displayed on ATA’s Web site and can be viewed at www.ata.org/get-involved/donor-recognition.We will be recognizing all $100+ donors in the April issues of Tinnitus Today for the previous calendar year. All contributions to the American Tinnitus Association are tax-deductible to the extent provided by law. For more information about giving to ATA, please contact Katie Fuller at (800) 634-8978 x220 or katie@ata.org. The gifts listed below include those from January 1, 2009 through June 30, 2009. Distinctive groups of individuals and organizations ATA is proud to have the following individuals and organizations support our research efforts and our crucial involvement in the tinnitus community.They include members of the Jack Vernon Legacy Society, those who have generously included ATA in their planned giving; our Corporate Membership Program; and Professional Membership Program. The lists below include memberships through June 30, 2009. Corporate Membership Program Anonymous (1) Virginia Blackman John U. Buchman, M.D. Carl L. Cochrane Simon Couvier Jules H. Drucker Joy A. Fogarty Drs. Norman and Gilda Greenberg D. G. Gumpertz Marcene M. Herron Ginger L. Hoiland Ben L. Jones Harold M. Kahn, Jr. Cliff Kohler Virginia L. Lipp Marita Maxey Mary B. Meikle, Ph.D. Ruth E. Ochs Edward P. Rosenberg James W. Soudriette Neil Valentino Delmer D. and Wanda Weisz Jack Vernon Legacy Society ATA offers a special thanks to our Founding Members, (names bolded below) who joined by June 30, 2008, and helped ATA successfully launch this great program. As of June 30, 2009, our Professional Membership Program includes: Research Champions Dhyan Cassie, Au.D., F/AAA Ali A. Danesh, Ph.D. Mary B. Meikle, Ph.D. Stephen P. Ratner, BC-HIS Michael J. A. Robb, M.D. Paula Schwartz, Au.D. Professional Members Dassan Ali, Sc.D., CCC-A Marcia L. Anderson, Au.D., FAAA Marty Ann Apa Au.D. Janie P. Barnett, Au.D. Kathleen Bartels, CCC-A/SLP Randall Bartlett, M.A. Linda Beach Denise Bickley, M.A., Au.D. Gail B. Brenner, Au.D., CCC-A Frank Cardarelli Max S. Chartrand, Ph.D. Alissa Claar, Au.D. Laurie Drake, Au.D. Professional Membership Program Timothy L. Drake, BC-HIS Michel Eybalin, Ph.D. Melodi B. Fehl, Au.D. Flash Gordon, M.D. Mark Gulliver MSc, Au.D.(C) James A. Henry, Ph.D. Sharon T. Hepfner, MA, FAAA Melanie Herzfeld, Au.D. Michael L. Hill, Au.D. Maria Holdren, M.S. Soraya Hoover, M.D., P.A. Jacquelyn C. Jackson, Au.D. Victor Jovan, BC-HIS Tae Yoo Kim Gregory D. King, Au.D., CCC-A Martin H. Kulick, D.M.D. John Kveton, M.D. Deborah R. Lain, B.A., MSc. Gail H. Leslie, Au.D. Malvina C. Levy, Au.D. Paula Liebeskind, M.S., CCC-A Joyce Lim Thomas J. Lobl, Ph.D. Michael Mallahan, Au.D. Randa Mansour-Shousher, Au.D. Maura G. Marks, Ph.D., Au.D, CCC-A/SLP Sara Mattson, Au.D. David L. Mehlum, M.D. Jill B. Meltzer, Au.D. Karen Mercer, M.A., FAAA Carl M. Nechtman, M.D., P.C. Alfred L. Nuttall, Ph.D. Phil Pack, M.S. Meredith K. L. Pang, M.D. Debbie Papadakis, M.Ht., BCH, C.I. Treva Paparella Margaret F. Peak, Ph.D. Stephen R. Plumlee Jean-Luc Puel, Ph.D. Donald E. Regan, Ph.D. Burke Richmond Terry L. Roberts, Au.D. Allen W. Rohe, Au.D., FAAA Sharon Rophie, Au.D. Roger A. Ruth, Ph.D. Gabrielle Sadowsky, CCC-A Katharine Sorenson, Au.D. Edward Szumowski, Au.D. Deborah L. Taylor, BC-HIS Wayne Tipps, D.D.S. University of Buffalo, Speech-Language & Hearing Clinic Erin Walborn, Au.D. Kim S. Worona, M.S.N., RN Contributing Donors $500-999 Patricia M. Atwood Arvest Bank Rod Barron Roberta M. Bartik Gary A. Bleiberg Marcia Powell Chapman, MSW James O. Chinnis Jr., Ph.D. Clear Products, Inc. Anthony G. A. Correa Frederick R. Entwistle, M.D. Flexion Therapeutics, Inc. Mark L. Goldberg John R. Grayson Fund Hearing Loss Association of America David Michael Keeter Jodi Klein Richard and Eva Klein Robert K. Mauer Michael J. A. Robb, M.D. Thomas Sylvest Tom J. Walen Delmer D. and Wanda Weisz Patricia H. Westheimer Raymond V. Wojtusiak J. Richard Yourtee TRIBUTES IN MEMORY OF: Grant Acker Henry Tobin, Ph.D. Nancy Anderson John and Faye Schleter Pamela Armstrong Adella Bratsos Terry Asbury Jack Asbury Bear Marco T. Carpio, M.D. and Linda E. Carpio, LCSW 26 Tinnitus Today | August 2009 Joyce A. Berger L. Ralph Berger Sandra Bloom John J. and Ann F. Henry Robert Branigan August E. Firgau Curtis H. Carlson Stephen C. Carlson Bert Cooper David S. and Nola Rothschild Theodore J.G. Cotter C.M Gucwa Joseph DeAngelo Rose DeAngelo Charles Goldstein Diane Schwab Edward Goodman Stuart J. and Marcy L. Feldman Trudy Gottfried Barsh Hearing Aid Center John Greve Catherine Greve Dorothy Guttenberg Stuart J. and Marcy L. Feldman Herbert Hand Donna Cronister Naena Grissett Nancy Huffman Florence Mugnolo Monte Nienkerk Dr. and Mrs. Ron Rainosek Steve Werner Leonard E. Johns Mrs. Leonard E. Johns James Ihasz Michael Bellizzi Bob Johnson Wayne Olsen Edward J. Keels Edward W. Keels Margie Keeter David Michael Keeter Stephen Klincik Karen K. Adams Nellie Koslosky Richard Koslosky Lettie Mannaway Alexander M. and Doris Friedman Ruby L. Masters Abbas Emami, M.D. David Loew Lisa Wilson James McLeod Michael Dorosh Irene Nelson Marco T. Carpio, M.D. and Linda E. Carpio, LCSW Karol C. Neiderfringer Alan Niederfinger Pennrose and Sallyann R. Wolf Alan Nickerson Stephen and Deborah Cohen Raymond Pantano Greg and Jacquie Amiriantz Linda Beach William A. Fiordimondo Ellen Pantano William Patterson Shreve High School Class of 1951 Leonore Mary Petito Rosemary C. Petito Steve Rodgers Scott A. Wilhelm Jonathan Rushing David N. and Mary Edna Rushing Elizabeth V. Saunders James C. Saunders, Ph.D. George Sciarrotta, Sr. Thomas Sciarrotta Theresa Senner Janice Kirkland Wanda Mae Shannon Jerry Shannon Merchant D. Slocum Elizabeth Holden Gert and Harold Soll Paul Soll Dana Lynn Spath Patricia Spath Charles Tecklenburg Morgan Keegan & Company, Inc. Daniel J. Jr. and Melissa A. Nordman Gerald N. and Patricia A. Padawer Terry J. and Kim T. Schott Paul E. Valentino Stephen Gulyas IN HONOR OF: Nick Andrews Kathi Holbrook John Bates Robin Ballenger Chet Carey Mr. and Mrs. Geoffrey Carey Patrick Collins James Collins John DeAtley Chris H. Hansen, CFP and John M. Britton of Personal Choice Financial Advisors Barth Engelman Marge Engleman Lisa Freeman Joan Tibbetts Craig Horn Jo Williams John Johnson Ellen J. Sharp Rose Kaput Stephen Gulyas Richard H. Keeter David Michael Keeter Jung Liu Anchi Miller David Loew Lisa Wilson Lois Lynch Isaac Lynch, Jr. Thomas Mathews Carrol G. Mathews Donald Mitchell, Jr. Donald Mitchell, Sr. Peny Nading Elaine Davis Edith Perschall Janice M. Stanley Dave Peters David W. Peters Mari Quigley-Miller Jonna DeBlasio The Ross Family Heidi Ross James Roth Barbara R. Roth Faye and John Schleter Sandra Schleter Charles Shaw K. Stern Joseph Smith David and Gail Cohen Tinnitus sufferers Janie P. Barnett, Au.D. Tinnitus victims of war Richard and Louise E. LaRosa Katy Thatch Donna Brown Brooklyn Marie Thomas Jack A. Vernon, Ph.D. and Mary B. Meikle, Ph.D. Peter J. Van Loon Greg Sorter Jack A. Vernon, Ph.D. James L. and Gail M. Shinn Jack A. Vernon, Ph.D. and Mary B. Meikle, Ph.D. Richard J. Salvi, Ph.D. Daniel Williams Alberta F. Williams Robert Williams Derwin and Charlotte Williams Sallyann Wolf Alan C. Niederfringer Matching Corps Allstate Chicago Tribune Foundation Gap, Inc. GE Foundation Illinois Tool Works Foundation Lorton Data, Inc. Microsoft Oracle Portland General Electric Co. Symetra Financial Corporate Visionaries $1,000 to 4,999 Corporate Leaders $500 to 999 Clear Products, Inc. Cooper Mountain Wines Flexion Therapeutics, Inc. Free-credit-reports.com, Inc. Paddy’s Bar & Grill Corporate Members $250 to 499 A1 Retrofit LLC Amplisound Bizon Nursery Elliot Law Offices James Robert Construction, LLC Lagunitas Beer NeuroSystec Corporation Pacific Marketing and Publishing Trademark Landscapes, Inc.
  • 27. Now you can support ATA’s work with safe, convenient monthly withdrawals from your bank or credit card company. Just tell us how much you want to contribute, and where you want it to come from. We’ll do the rest. With three easy ways to sign up, there’s a monthly giving approach for everyone. Use the form below, sign up online at www.ata.org, or call us at (800) 634-8978 x221 and ask for information on the Monthly Giving program. It’s that simple. Sign up once, and know that you are regularly supporting the important work that will cure tinnitus. No More Checks... ...A Little More Time Yes, I am proud to become an ATA Monthly Giving Donor. Sign me up! Name: ATA Member Number: Address: E-mail: City: State: Zip: Phone: I would like my monthly gift to be * $100 * $50 * $25 * $10 * $5 * Other $ * Transfer from my checking account. A check for my first monthly contribution is enclosed. * Charge my debit/credit card. * Visa * MasterCard * American Express * Discover Card Number: - - - - Expiration Date: I authorize ATA to charge my debit/credit card. Signature: ATA monthly gift transfers comply with U.S. law. ATA charges your bank or credit card on or near the 15th of each month. A record of each gift will appear on the monthly statement issued by your bank or credit card company. ATA will provide a year-end statement of the annual contribution. Mail this form to: American Tinnitus Association • P.O. Box 5 • Portland, OR 97207
  • 28. P.O. Box 5 Portland, OR 97207-0005 Address Service Requested shop ATA www.ata.org Bilsom Thunder T3 Ear Muffs NRR-30dB ($19.95 ATA Members / $21.95 Non-Members) Bilsom Thunder T3 ear muffs have a strong noise reduction rating (NRR) of 30dB, making them perfect for noisy environments. Their dielectric construction is suitable for MRI machines and all workplaces. Features patented Air Flow Control technology for optimal attenuation across all frequencies. Color: Dark green Remington Kids Ear Muffs NRR-22dB ($12.95 ATA Members / $14.95 Non-Members) Remington Youth ear muffs are lightweight with a ventilated headband. Their dielectric construc- tion is suitable for MRI machines and have a noise reduction rating (NRR) of 22dB. Recom- mended for children age 5 through teens. Color: Blue-Green / Yellow trim SparkPlugs Ear Plugs 5-pair set NRR-33dB ($2.50 ATA Members / $3.00 Non-Members) SparkPlugs ear plugs are made of extra-soft, extra-light foam and are the official ear plugs of NASCAR! Their tapered shape fits easily in the ear canal, and seals gently and snugly without pressure. SparkPlugs ear plugs offer a high NRR-33dB, making them suitable for most noisy environments. Color: Mixed Ohropax Classic Moldable Wax Ear Plugs 6-pair set NRR-22dB ($4.95 ATA Members / $5.50 Non-Members) Ohropax Classic ear plugs have been an established, German-made noise protection product since 1907. These wax moldable ear plugs can be adjusted to fit every auditory canal and considerably reduce the effects of noise pollution with a noise reduction rating of 22dB. Six pairs in metal carrying case. Color: Peach Etymotic Research ER-20 Hi-Fidelity Ear Plugs NRR-20dB ($10.95 ATA Members / $11.95 Non-Members) Etymotic ER-20 Hi-Fi Natural Sound Ear Plugs feature patented Hi-Fi technology that lets you hear all frequencies clearly, but at a lower volume level. Reduce sound levels approximately 20dB. ER-20 ear plugs are washable, reusable and durable. With proper care they will last for months even with daily use. Color: White plug, clear stem Etymotic Research ER-20 Baby Blues Ear Plugs NRR-20dB ($10.95 ATA Members / $11.95 Non-Members) Designed for the smaller ear canal in mind, Etymotic ER 20 Hi-Fi Natural Sound Ear Plugs feature patented Hi-Fi technology that lets you hear all frequencies clearly, but at a lower volume level. Reduce sound levels approximately 20dB. Baby Blues plugs are washable, reusable and durable. With proper care they will last for months even with daily use. NOT recommended for children under age 5. Color: Blue plug, clear stem Tinnitus: Turning the Volume Down (Revised & Expanded Edition) by Kevin Hogan, Psy.D., and Jennifer Battaglino, LCSW ($22.95 ATA Members / $24.95 Non-Members) This revised and expanded book contains a decade of proven strategies for quieting the noise in your head. Details the evolution of tinnitus research and discusses various causes and tinnitus treatment options. (260 pages, soft cover) Noise and Military Service: Implications for Hearing Loss and Tinnitus by Larry E. Humes, Lois M. Joellenbeck and Jane S. Durch ($59.95 ATA Members / $62.95 Non-Members) Findings are presented from studies on hazardous noise in military settings, levels of exposure necessary to cause hearing loss or tinnitus, risk factors, the timing of the effects of noise exposure on hearing and the adequacy of military hearing conservation programs, including audiometric testing. (338 pages, soft cover) Hyperacusis: Mechanisms, Diagnosis, and Therapies by Davis M. Baguley, Ph.D., and Gerhard Andersson, Ph.D. ($68.95 ATA Members / $69.95 Non-Members) Explores what is currently known about hyperacusis from the disciplines of neurosci- ence, psychology and audiology. The authors integrate theory with practice and provide coherent analyses of current research. (114 pages, hard cover) AMERICAN TINNITUS ASSOCIATION AUDIO COLLECTION New ATA-produced CDs. Special-value price of only $2.50 each for ATA members! SHOP THE STORE & SAVE TODAY! Non-Profit Org. U.S. Postage PAID American Tinnitus Association