The document summarizes the rise and fall of performance-enhancing drug (PED) use in Major League Baseball (MLB). It describes how PED use peaked in the 1990s-2000s as players broke home run records, but has since declined due to increased drug testing, revelations of drug use in books and investigations, and the stigma around known PED users being denied entry to the Hall of Fame. Notable players who used PEDs include Barry Bonds, Mark McGwire, Alex Rodriguez, and Roger Clemens. Fewer players are now being implicated or testing positive for PED use.