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The benefits of making your clinical trial more patient-centric
- 1. © 2016 THE MEDICAL RESEARCH NETWORK. ALL RIGHTS RESERVED. MRN APPROACH TO PATIENT-CENTRIC CLINICAL TRIALS TEL: +44 (0)1908 261 153 EMAIL: ENQUIRIES@THEMRN.CO.UK WEB: WWW.THEMRN.CO.UK INDUSTRY CHALLENGES 94% 30% 1 IN 4 48% OF PATIENTS DO NOT RETENTION RATES OF SITES RECRUIT 1 PATIENT OR LESS HAVE FALLEN IN RECENT YEARS HAVE ACCESS TO TRIALS PROCESS COMPARISON SITE PATIENTS PATIENTS PHARMACY LAB CRA CRA NURSE SITE THE OLD PROCESS THE MRN PROCESS HOMECARE NURSE LAB PHARMACY COMPLETEDSCREENINGCONSENTONGOINGPRE-SCREENING PATIENT RECRUITMENT & RETENTION TRADITIONAL HOME TRIAL SUPPORT SITE NURSE SUPPORT & HOME TRIAL SUPPORT SIMPLE SIMPLE COMPLEX SIMPLE 4.2 3.5 7.0 7.0 2.6 2.5 2.1 2.2 COMPLEX SIMPLE COMPLEX SIMPLE COMPLEX 59 SIMPLE COMPLEX SIMPLE 8.4 7.0 13.9 13.9 5.2 4.9 3.7 4.4 COMPLEX SIMPLE COMPLEX SIMPLE COMPLEX 59 RECRUITMENT RATES PATIENTS DROP OUT BEFORE STUDY COMPLETION THE IMPACT OF GREATER REACH SIMPLE COMPLEX SIMPLE 1.6 1.1 3.9 3.9 1.0 0.8 0.5 0.7 COMPLEX SIMPLE COMPLEX SIMPLE COMPLEX 33 A SITE TRADITIONAL HOME TRIAL SUPPORT SITE NURSE SUPPORT & HOME TRIAL SUPPORT A B SITE A B SITE ZONE RADIUS POPULATION DENSITY % POPULATION ACCESSED PATIENT POOL AVAILABLE A 10 MILES 160 100% 33 B 50 MILES 3100 180% 59 PATIENTS TIME (MONTHS) HTS & SNS HTS TRADITIONAL 180% 100% 8.5 10 12 APPROACHEDPATIENTPOOL Implementing Home Trial Support allows sites to recruit patients from a wider geographical region and therefore reach a larger patient pool, as well as increase their consenting and retention rates. Implementing Site Nurse Support in parallel ensures sites have a dedicated resource to identify and screen patients from the increased patient pool effectively. The combined impact of these services can result in up to 600% increase in completed patients per site. MRN is the largest nursing provider in the clinical trials sector, covering over 38 countries worldwide, with innovative tools to deliver your projects. We specialize in the COMPLEX; studies with large numbers of countries, studies where IMP needs to be delivered in the home, as well as studies with difficult patient populations - specifically paediatrics and rare diseases. 17.9 35.810 *Estimated for Pharma Sponsored Clinical Trials Home Trial Support allows recruitment of patients living further from the site. SIMPLE: Blood draws and data collection COMPLEX: IMP administration, blood draws and data collection