Ayahuasca is a brew made from plants like the ayahuasca vine and chacruna leaf that has been used for thousands of years by indigenous groups in the Amazon for healing and spiritual purposes. It is ingested ceremonially and can produce powerful visions and purging. Vomiting is seen as the first stage of cleansing the body and spirit, and helps kickstart the visionary effects. Research has shown that ayahuasca ceremonies can provide mental, psychological, and spiritual benefits comparable to long-term psychotherapy in addressing issues not helped by conventional treatment.