Surrogate mothers receive hormone medications before and during pregnancy to supplement the hormones needed to carry a child. These include antibiotics to prevent infection, birth control pills or progesterone pills to synchronize the surrogate's cycle with the egg donor's, and injections of Lupron to medically shut down the surrogate's natural cycle. Once the lining of the uterus is thickened using estrogen, progesterone is given to make the uterus receptive for embryo implantation and to maintain the pregnancy. Ultrasounds and blood tests are used to monitor hormone levels and uterine thickness. If implantation is successful, estrogen and progesterone are generally continued through the first trimester until the placenta takes over hormone production. Side effects of the hormone treatments may include bloating, irrit

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2. Our body prepares an expectant mother by releasing all the hormones necessary to carry a child till its birth.
It makes the uterus ready for conception and then helps the embryo to be stable and grow. But in the case of
a surrogate mother, she needs to be given medications before and after the pregnancy to supplement the
required hormones released naturally to others.
Surrogate mothers in India receive same medications that is being followed elsewhere in other parts of the
world. In the run up to this a surrogate mother is given anti biotic to rule out any possible pelvic infection.
Once the vital parameters of a surrogate mother are within the reference range and all the screening process
gets completed, the surrogate receives medication to start the treatment. The cycle of the surrogate mother
should match with the egg donor. If the cycle of the surrogate mother doesn’t match with that of donor, the
cycle is matched by giving hormonal pills ie. birth control pills or progesterone pills. Lupride acetate is the
medicine that need to be started from day 2 of recipient’s cycle to supress her ovaries and prevent hormonal
interference in the pregnancy. Birth control pills may be started about a fortnight before Lupron. Injection of
Lupron completely shuts down the surrogate’s own cycle medically and a synchronized cycle with egg donor
is started. Lupron should be stopped prior to egg donation of the intended mother or egg donor.

3. Hormonal injections/medications will be given to enhance thickness of the endometrium. These hormones are
known as Estrogen and Progesterone. Estrogen helps to thicken the lining of the uterus and it can be taken orally or
other methods like injection or via abdomen skin patch to get absorbed in the body. Once the lining thickens and
reaches critical thickness, hormone progesterone is administered to make the secretory changes in endometrium to
make it receptive for implantation and to maintain pregnancy. Progesterone also can be given subcutaneous, orally or
as vaginal tablet. In the journey towards Surrogacy weekly ultra sound and blood tests will be performed to check the
thickness of the lining and hormonal level. Ultrasound and Blood test confirming the level of Progesterone helps IVF
Specialist to understand whether the uterus is ready for the embryo and attained the optimum level of conception.
On the 5th day of progesterone injection, blastocyst ie. Day 5 embryo is transferred to the recipient.The topic of
Blastocyst embryo transfer will be discussed separately.To maintain a stable balance and help the uterus to retain
the embryo, Progesterone should be continued till beta hCG test that confirms pregnancy and is continued further if
pregnancy test is positive.
Once the implant is successful and the pregnancy is confirmed, Estrogen and Progesterone are generally continued
till first trimester.The placenta then takes over hormone production and these medications are not required
routinely. In some cases Aspirin is given orally to improve implantation rates.The rest of the medication is as per
pregnancy similar to other pregnancies.A surrogate mother will have to take vitamin supplements and iron tablets
during her pre natal journey. She should have a healthy diet along with medication with some exercise to keep her
fit and prepare suitably for the journey.

4. Side Effects of the hormone
injections could be bloating,
irritability and tenderness
of the injection site. Some
experience dizziness and
fatigue also with vaginal
discharge. Oral tablets can
cause constipation, minor
stomach upset.There are
many good Surrogacy
treatment centres in India
where surrogate mom’s
medication gets full
attention as every woman is
different from the other
and needs a separate
medication chart.

5. We are available @ www.matrikamedicare.com or call us in the numbers 011
4145 9114 or +91 9899481003. All your queries will be answered within a short
period of time.