Growing plants with LED grow lights requires balancing multiple variables like nutrition, watering, temperature, and light coverage. Proper adjustment of these growth factors over time will result in healthy, beautiful plants. Some tips for successful plant growth with LEDs include placing the lights closer to the plants due to their low heat output, consulting light specifications before purchasing, and adjusting watering and nutrients given that plants need fewer under LED lights which create less heat than conventional lights. Environmental conditions like temperature also need adjustment to account for the lower heat from LEDs, with most plants growing optimally between 68F to 86F.