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Standards of Medical Care in Diabetesd2017:
Summary of Revisions
Diabetes Care 2017;40(Suppl. 1):S4–S5 | DOI: 10.2337/dc17-S003
GENERAL CHANGES
In light of the American Diabetes Associa-
tion’s (ADA’s) new position statement on
psychosocial care in the treatment of di-
abetes, the “Standards of Medical Care in
Diabetes,” referred to as the “Standards of
Care,” has been updated to address psy-
chosocial issues in all aspects of care in-
cluding self-management, mental health,
communication, complications, comorbid-
ities, and life-stage considerations.
Although levels of evidence for several
recommendations have been updated,
these changes are not addressed below
as the clinical recommendations have re-
mained the same. Changes in evidence
level from, for example, E to C are not
noted below. The 2017 Standards of
Care contains, in addition to many minor
changes that clarify recommendations or
reflect new evidence, the following more
substantive revisions.
SECTION CHANGES
Section 1. Promoting Health and
Reducing Disparities in Populations
This section was renamed and now fo-
cuses on improving outcomes and re-
ducing disparities in populations with
diabetes.
Recommendations were added to as-
sess patients’ social context as well as
refer to local community resources and
provide self-management support.
Section 2. Classification and Diagnosis
of Diabetes
The section was updated to include a
new consensus on the staging of type 1
diabetes (Table 2.1) and a discussion of a
proposed unifying diabetes classification
scheme that focuses on b-cell dysfunc-
tion and disease stage as indicated by
glucose status.
Language was added to clarify screen-
ing and testing for diabetes. Screening
approaches were described, and Fig. 2.1
was included to provide an example of a
validatedtooltoscreenforprediabetesand
previously undiagnosed type 2 diabetes.
Due to recent data, delivering a baby
weighing 9 lb or more is no longer listed
as an independent risk factor for the
development of prediabetes and type 2
diabetes.
A section was added that discusses
recent evidence on screening for diabe-
tes in dental practices.
The recommendation to test women
with gestational diabetes mellitus for
persistent diabetes was changed from
6–12 weeks’ postpartum to 4–12 weeks’
postpartum to allow the test to be sched-
uled just before the standard 6-week post-
partum obstetrical checkup so that the
results can be discussed with the patient
at that time of the visit or to allow the test
to be rescheduled at the visit if the patient
did not get the test.
Additional detail was added to the
section on monogenic diabetes syn-
dromes, and a new table was added (Ta-
ble 2.7) describing the most common
forms of monogenic diabetes.
A new section was added on post-
transplantation diabetes mellitus.
Section 3. Comprehensive Medical
Evaluation and Assessment of
Comorbidities
This new section, including components
of the 2016 section “Foundations of
Care and Comprehensive Medical Eval-
uation,” highlights the importance of
assessing comorbidities in the context
of a patient-centered comprehensive
medical evaluation.
A new discussion of the goals of provider-
patient communication is included.
The Standards of Care now recom-
mends the assessment of sleep pattern
and duration as part of the comprehensive
medical evaluation based on emerging ev-
idence suggesting a relationship between
sleep quality and glycemic control.
An expanded list of diabetes comorbid-
ities now includes autoimmune diseases,
HIV, anxiety disorders, depression, disor-
dered eating behavior, and serious mental
illness.
Section 4. Lifestyle Management
This section, previously entitled “Foun-
dations of Care and Comprehensive
Medical Evaluation,” was refocused on
lifestyle management.
The recommendation for nutrition
therapy in people prescribed flexible in-
sulin therapy was updated to include fat
and protein counting in addition to car-
bohydrate counting for some patients to
reflect evidence that these dietary fac-
tors influence insulin dosing and blood
glucose levels.
Based on new evidence of glycemic
benefits, the Standards of Care now
recommends that prolonged sitting be
interrupted every 30 min with short
bouts of physical activity.
A recommendation was added to
highlight the importance of balance
and flexibility training in older adults.
A new section and table provide infor-
mation on situations that might warrant
referral to a mental health provider.
Section 5. Prevention or Delay of
Type 2 Diabetes
To help providers identify those patients
who would benefit from prevention ef-
forts, new text was added emphasizing
the importance of screening for prediabe-
tes using an assessment tool or informal
assessment of risk factors and performing
a diagnostic test when appropriate.
To reflect new evidence showing an
association between B12 deficiency and
long-term metformin use, a recommen-
dation was added to consider periodic
© 2017 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit,
and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.
S4 Diabetes Care Volume 40, Supplement 1, January 2017
SUMMARYOFREVISIONS
measurement of B12 levels and supple-
mentation as needed.
Section 6. Glycemic Targets
Based on recommendations from the In-
ternational Hypoglycaemia Study Group,
serious, clinically significant hypoglycemia
is now defined as glucose ,54 mg/dL
(3.0 mmol/L), while the glucose alert value
is defined as #70 mg/dL (3.9 mmol/L) (Ta-
ble6.3).Clinicalimplicationsare discussed.
Section 7. Obesity Management for
the Treatment of Type 2 Diabetes
To be consistent with other ADA position
statements and to reinforce the role of
surgery in the treatment of type 2 diabe-
tes, bariatric surgery is now referred to as
metabolic surgery.
To reflect the results of an international
workgroup report endorsed by the ADA
and many other organizations, recommen-
dations regarding metabolic surgery
have been substantially changed, in-
cluding those related to BMI thresholds
for surgical candidacy (Table 7.1), men-
tal health assessment, and appropriate
surgical venues.
Section 8. Pharmacologic Approaches
to Glycemic Treatment
The title of this section was changed from
“Approaches to Glycemic Treatment” to
“Pharmacologic Approaches to Glycemic
Treatment” to reinforce that the section
focuses on pharmacologic therapy alone.
Lifestyle management and obesity manage-
ment are discussed in separate chapters.
To reflect new evidence showing an as-
sociation between B12 deficiency and long-
term metformin use, a recommendation
was added to consider periodic measure-
ment of B12 levels and supplementation
as needed.
A section was added describing the
role of newly available biosimilar insu-
lins in diabetes care.
Based on the results of two large clin-
ical trials, a recommendation was added
to consider empagliflozin or liraglutide in
patients with established cardiovascular
disease to reduce the risk of mortality.
Figure 8.1, antihyperglycemic ther-
apy in type 2 diabetes, was updated to
acknowledge the high cost of insulin.
The algorithm for the use of combina-
tion injectable therapy in patients with
type2diabetes(Fig.8.2)hasbeenchanged
to reflect studies demonstrating the non-
inferiority of basal insulin plus glucagon-
likepeptide1receptoragonistversusbasal
insulin plus rapid-acting insulin versus two
daily injections of premixed insulin, as well
as studies demonstrating the noninferior-
ity of multiple dose premixed insulin regi-
mens versus basal-bolus therapy.
Due toconcernsabout the affordability
of antihyperglycemic agents, new tables
were added showing the median costs of
noninsulin agents (Table 8.2) and insulins
(Table 8.3).
Section 9. Cardiovascular Disease and
Risk Management
To better align with existing data, the hy-
pertension treatment recommendation
for diabetes now suggests that, for pa-
tients without albuminuria, any of the
fourclassesofblood pressure medications
(ACE inhibitors, angiotensin receptor
blockers, thiazide-like diuretics, or dihy-
dropyridine calcium channel blockers)
that have shown beneficial cardiovascular
outcomes may be used.
To optimize maternal health without
risking fetal harm, the recommendation
for the treatment of pregnant patients
with diabetes and chronic hypertension
was changed to suggest a blood pressure
target of 120–160/80–105 mmHg.
Asectionwasaddeddescribingthecardio-
vascular outcome trials that demonstrated
benefits of empagliflozin and liraglutide in
certain high-risk patients with diabetes.
Section 10. Microvascular
Complications and Foot Care
A recommendation was added to high-
light the importance of provider commu-
nication regarding the increased risk of
retinopathy in women with preexisting
type 1 or type 2 diabetes who are plan-
ning pregnancy or who are pregnant.
The section now includes specific rec-
ommendations for the treatment of
neuropathic pain.
A new recommendation highlights
the benefits of specialized therapeutic
footwear for patients at high risk for
foot problems.
Section 12. Children and Adolescents
Additional recommendations highlight
the importance of assessment and re-
ferral for psychosocial issues in youth.
Due to the risk of malformations asso-
ciated with unplanned pregnancies and
poor metabolic control, a new recom-
mendation was added encouraging pre-
conception counseling starting at puberty
for all girls of childbearing potential.
To address diagnostic challenges asso-
ciated with the current obesity epidemic,
a discussion was added about distinguish-
ing between type 1 and type 2 diabetes in
youth.
A section was added describing recent
nonrandomized studies of metabolic sur-
gery for the treatment of obese adoles-
cents with type 2 diabetes.
Section 13. Management of Diabetes
in Pregnancy
Insulin was emphasized as the treatment
of choice in pregnancy based on concerns
about the concentration of metformin on
the fetal side of the placenta and glyburide
levels in cord blood.
Based on available data, preprandial
self-monitoring of blood glucose was
deemphasized in the management of
diabetes in pregnancy.
In the interest of simplicity, fasting and
postprandial targets for pregnant women
with gestational diabetes mellitus and
preexisting diabetes were unified.
Section 14. Diabetes Care in the
Hospital
This section was reorganized for clarity.
A treatment recommendation was up-
dated to clarify that either basal insulin or
basal plus bolus correctional insulin
may be used in the treatment of non-
critically ill patients with diabetes in a
hospital setting, but not sliding scale
alone.
The recommendations for insulin dos-
ing for enteral/parenteral feedings were
expanded to provide greater detail on in-
sulin type, timing, dosage, correctional, and
nutritional considerations.
care.diabetesjournals.org Summary of Revisions S5

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Standards of Medical Care in Diabetes 2017 Summary

  • 1. Standards of Medical Care in Diabetesd2017: Summary of Revisions Diabetes Care 2017;40(Suppl. 1):S4–S5 | DOI: 10.2337/dc17-S003 GENERAL CHANGES In light of the American Diabetes Associa- tion’s (ADA’s) new position statement on psychosocial care in the treatment of di- abetes, the “Standards of Medical Care in Diabetes,” referred to as the “Standards of Care,” has been updated to address psy- chosocial issues in all aspects of care in- cluding self-management, mental health, communication, complications, comorbid- ities, and life-stage considerations. Although levels of evidence for several recommendations have been updated, these changes are not addressed below as the clinical recommendations have re- mained the same. Changes in evidence level from, for example, E to C are not noted below. The 2017 Standards of Care contains, in addition to many minor changes that clarify recommendations or reflect new evidence, the following more substantive revisions. SECTION CHANGES Section 1. Promoting Health and Reducing Disparities in Populations This section was renamed and now fo- cuses on improving outcomes and re- ducing disparities in populations with diabetes. Recommendations were added to as- sess patients’ social context as well as refer to local community resources and provide self-management support. Section 2. Classification and Diagnosis of Diabetes The section was updated to include a new consensus on the staging of type 1 diabetes (Table 2.1) and a discussion of a proposed unifying diabetes classification scheme that focuses on b-cell dysfunc- tion and disease stage as indicated by glucose status. Language was added to clarify screen- ing and testing for diabetes. Screening approaches were described, and Fig. 2.1 was included to provide an example of a validatedtooltoscreenforprediabetesand previously undiagnosed type 2 diabetes. Due to recent data, delivering a baby weighing 9 lb or more is no longer listed as an independent risk factor for the development of prediabetes and type 2 diabetes. A section was added that discusses recent evidence on screening for diabe- tes in dental practices. The recommendation to test women with gestational diabetes mellitus for persistent diabetes was changed from 6–12 weeks’ postpartum to 4–12 weeks’ postpartum to allow the test to be sched- uled just before the standard 6-week post- partum obstetrical checkup so that the results can be discussed with the patient at that time of the visit or to allow the test to be rescheduled at the visit if the patient did not get the test. Additional detail was added to the section on monogenic diabetes syn- dromes, and a new table was added (Ta- ble 2.7) describing the most common forms of monogenic diabetes. A new section was added on post- transplantation diabetes mellitus. Section 3. Comprehensive Medical Evaluation and Assessment of Comorbidities This new section, including components of the 2016 section “Foundations of Care and Comprehensive Medical Eval- uation,” highlights the importance of assessing comorbidities in the context of a patient-centered comprehensive medical evaluation. A new discussion of the goals of provider- patient communication is included. The Standards of Care now recom- mends the assessment of sleep pattern and duration as part of the comprehensive medical evaluation based on emerging ev- idence suggesting a relationship between sleep quality and glycemic control. An expanded list of diabetes comorbid- ities now includes autoimmune diseases, HIV, anxiety disorders, depression, disor- dered eating behavior, and serious mental illness. Section 4. Lifestyle Management This section, previously entitled “Foun- dations of Care and Comprehensive Medical Evaluation,” was refocused on lifestyle management. The recommendation for nutrition therapy in people prescribed flexible in- sulin therapy was updated to include fat and protein counting in addition to car- bohydrate counting for some patients to reflect evidence that these dietary fac- tors influence insulin dosing and blood glucose levels. Based on new evidence of glycemic benefits, the Standards of Care now recommends that prolonged sitting be interrupted every 30 min with short bouts of physical activity. A recommendation was added to highlight the importance of balance and flexibility training in older adults. A new section and table provide infor- mation on situations that might warrant referral to a mental health provider. Section 5. Prevention or Delay of Type 2 Diabetes To help providers identify those patients who would benefit from prevention ef- forts, new text was added emphasizing the importance of screening for prediabe- tes using an assessment tool or informal assessment of risk factors and performing a diagnostic test when appropriate. To reflect new evidence showing an association between B12 deficiency and long-term metformin use, a recommen- dation was added to consider periodic © 2017 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license. S4 Diabetes Care Volume 40, Supplement 1, January 2017 SUMMARYOFREVISIONS
  • 2. measurement of B12 levels and supple- mentation as needed. Section 6. Glycemic Targets Based on recommendations from the In- ternational Hypoglycaemia Study Group, serious, clinically significant hypoglycemia is now defined as glucose ,54 mg/dL (3.0 mmol/L), while the glucose alert value is defined as #70 mg/dL (3.9 mmol/L) (Ta- ble6.3).Clinicalimplicationsare discussed. Section 7. Obesity Management for the Treatment of Type 2 Diabetes To be consistent with other ADA position statements and to reinforce the role of surgery in the treatment of type 2 diabe- tes, bariatric surgery is now referred to as metabolic surgery. To reflect the results of an international workgroup report endorsed by the ADA and many other organizations, recommen- dations regarding metabolic surgery have been substantially changed, in- cluding those related to BMI thresholds for surgical candidacy (Table 7.1), men- tal health assessment, and appropriate surgical venues. Section 8. Pharmacologic Approaches to Glycemic Treatment The title of this section was changed from “Approaches to Glycemic Treatment” to “Pharmacologic Approaches to Glycemic Treatment” to reinforce that the section focuses on pharmacologic therapy alone. Lifestyle management and obesity manage- ment are discussed in separate chapters. To reflect new evidence showing an as- sociation between B12 deficiency and long- term metformin use, a recommendation was added to consider periodic measure- ment of B12 levels and supplementation as needed. A section was added describing the role of newly available biosimilar insu- lins in diabetes care. Based on the results of two large clin- ical trials, a recommendation was added to consider empagliflozin or liraglutide in patients with established cardiovascular disease to reduce the risk of mortality. Figure 8.1, antihyperglycemic ther- apy in type 2 diabetes, was updated to acknowledge the high cost of insulin. The algorithm for the use of combina- tion injectable therapy in patients with type2diabetes(Fig.8.2)hasbeenchanged to reflect studies demonstrating the non- inferiority of basal insulin plus glucagon- likepeptide1receptoragonistversusbasal insulin plus rapid-acting insulin versus two daily injections of premixed insulin, as well as studies demonstrating the noninferior- ity of multiple dose premixed insulin regi- mens versus basal-bolus therapy. Due toconcernsabout the affordability of antihyperglycemic agents, new tables were added showing the median costs of noninsulin agents (Table 8.2) and insulins (Table 8.3). Section 9. Cardiovascular Disease and Risk Management To better align with existing data, the hy- pertension treatment recommendation for diabetes now suggests that, for pa- tients without albuminuria, any of the fourclassesofblood pressure medications (ACE inhibitors, angiotensin receptor blockers, thiazide-like diuretics, or dihy- dropyridine calcium channel blockers) that have shown beneficial cardiovascular outcomes may be used. To optimize maternal health without risking fetal harm, the recommendation for the treatment of pregnant patients with diabetes and chronic hypertension was changed to suggest a blood pressure target of 120–160/80–105 mmHg. Asectionwasaddeddescribingthecardio- vascular outcome trials that demonstrated benefits of empagliflozin and liraglutide in certain high-risk patients with diabetes. Section 10. Microvascular Complications and Foot Care A recommendation was added to high- light the importance of provider commu- nication regarding the increased risk of retinopathy in women with preexisting type 1 or type 2 diabetes who are plan- ning pregnancy or who are pregnant. The section now includes specific rec- ommendations for the treatment of neuropathic pain. A new recommendation highlights the benefits of specialized therapeutic footwear for patients at high risk for foot problems. Section 12. Children and Adolescents Additional recommendations highlight the importance of assessment and re- ferral for psychosocial issues in youth. Due to the risk of malformations asso- ciated with unplanned pregnancies and poor metabolic control, a new recom- mendation was added encouraging pre- conception counseling starting at puberty for all girls of childbearing potential. To address diagnostic challenges asso- ciated with the current obesity epidemic, a discussion was added about distinguish- ing between type 1 and type 2 diabetes in youth. A section was added describing recent nonrandomized studies of metabolic sur- gery for the treatment of obese adoles- cents with type 2 diabetes. Section 13. Management of Diabetes in Pregnancy Insulin was emphasized as the treatment of choice in pregnancy based on concerns about the concentration of metformin on the fetal side of the placenta and glyburide levels in cord blood. Based on available data, preprandial self-monitoring of blood glucose was deemphasized in the management of diabetes in pregnancy. In the interest of simplicity, fasting and postprandial targets for pregnant women with gestational diabetes mellitus and preexisting diabetes were unified. Section 14. Diabetes Care in the Hospital This section was reorganized for clarity. A treatment recommendation was up- dated to clarify that either basal insulin or basal plus bolus correctional insulin may be used in the treatment of non- critically ill patients with diabetes in a hospital setting, but not sliding scale alone. The recommendations for insulin dos- ing for enteral/parenteral feedings were expanded to provide greater detail on in- sulin type, timing, dosage, correctional, and nutritional considerations. care.diabetesjournals.org Summary of Revisions S5