El documento discute las diferencias entre el marketing tradicional (4P) y el marketing digital (4C). El marketing tradicional se enfoca en el producto, precio, promoción y plaza, mientras que el marketing digital se enfoca en el contenido, comunidad, comunicación y conveniencia. El marketing digital se adapta mejor a las necesidades del cliente al permitir un diálogo interactivo y proporcionar contenido relevante.
This document discusses a study that evaluated the readiness of SNOMED CT concept descriptors for use in primary care. Researchers analyzed four random samples of SNOMED concepts totaling 442 concepts using a simulated clinical scenario. They found significant issues in 62% of one sample, including erroneous synonyms, duplicate concepts, and improper use of container classes. While issues were less common in other samples, the study suggests SNOMED complexity may make average users unable to easily select the correct concept in some cases. Recommendations include improving editorial policies and developing well-curated reference datasets.
The document describes COMPACT, a database for analyzing common eligibility features in clinical trials. It extracts metadata, categorical features, and numeric features from trial summaries on ClinicalTrials.gov using natural language processing. Analysis of Type 2 diabetes trials in COMPACT found common categorical features like diabetes and metformin use. Numeric features like HbA1c levels and BMI were frequently used, often with value ranges of 7.0-10.0% and 25.0-40.0 respectively. The database and a visualization tool called VITTA are resources for understanding trial population design and improving generalizability. Future work includes enhancing feature analysis and comparing trial populations to patient populations.
This document proposes a family-based framework for quality assurance of biomedical ontologies in BioPortal. It analyzes 186 ontologies from BioPortal and categorizes them into 7 families based on their structural features. For each family, it defines a unified abstraction network and quality assurance methodology. As an example, it applies the framework to the Cancer Chemoprevention Ontology and identifies errors, which were addressed in a newer version. The framework aims to improve the scalability and efficiency of quality assurance for the large number of ontologies in BioPortal.
This document proposes a family-based framework for quality assurance of biomedical ontologies in BioPortal. It analyzes 186 ontologies from BioPortal and categorizes them into 7 families based on their structural features. For each family, it defines a unified abstraction network and quality assurance methodology. As an example, it applies the framework to the Cancer Chemoprevention Ontology, identifies errors, and shows how the ontology was improved. The framework aims to improve the scalability and efficiency of quality assurance for the large number of ontologies in BioPortal.
The document describes an algorithm called "Hide" that identifies and removes redundant import of classes from a top-level ontology into a domain ontology. It was developed to improve quality assurance of ontologies by removing unused imported classes. The algorithm is demonstrated by applying it to the Drug Discovery Investigations (DDI) ontology, where it identified and hid 18 out of 32 imported Basic Formal Ontology (BFO) classes that were not used in DDI. Future work is needed to handle more complex ontology structures and relationships between classes.
El documento resume la historia y evolución del mercadeo a través de varias etapas. Inicialmente, durante la etapa de autosuficiencia económica, los grupos familiares producían solo para su propio consumo. Luego, con la aparición de la división del trabajo, surgió la etapa del trueque, donde los excedentes de producción eran intercambiados entre grupos. Más adelante, la introducción de la moneda durante la etapa monetaria facilitó el comercio nacional e internacional. Finalmente, en las décadas
El documento discute las diferencias entre el marketing tradicional (4P) y el marketing digital (4C). El marketing tradicional se enfoca en el producto, precio, promoción y plaza, mientras que el marketing digital se enfoca en el contenido, comunidad, comunicación y conveniencia. El marketing digital se adapta mejor a las necesidades del cliente al permitir un diálogo interactivo y proporcionar contenido relevante.
This document discusses a study that evaluated the readiness of SNOMED CT concept descriptors for use in primary care. Researchers analyzed four random samples of SNOMED concepts totaling 442 concepts using a simulated clinical scenario. They found significant issues in 62% of one sample, including erroneous synonyms, duplicate concepts, and improper use of container classes. While issues were less common in other samples, the study suggests SNOMED complexity may make average users unable to easily select the correct concept in some cases. Recommendations include improving editorial policies and developing well-curated reference datasets.
The document describes COMPACT, a database for analyzing common eligibility features in clinical trials. It extracts metadata, categorical features, and numeric features from trial summaries on ClinicalTrials.gov using natural language processing. Analysis of Type 2 diabetes trials in COMPACT found common categorical features like diabetes and metformin use. Numeric features like HbA1c levels and BMI were frequently used, often with value ranges of 7.0-10.0% and 25.0-40.0 respectively. The database and a visualization tool called VITTA are resources for understanding trial population design and improving generalizability. Future work includes enhancing feature analysis and comparing trial populations to patient populations.
This document proposes a family-based framework for quality assurance of biomedical ontologies in BioPortal. It analyzes 186 ontologies from BioPortal and categorizes them into 7 families based on their structural features. For each family, it defines a unified abstraction network and quality assurance methodology. As an example, it applies the framework to the Cancer Chemoprevention Ontology and identifies errors, which were addressed in a newer version. The framework aims to improve the scalability and efficiency of quality assurance for the large number of ontologies in BioPortal.
This document proposes a family-based framework for quality assurance of biomedical ontologies in BioPortal. It analyzes 186 ontologies from BioPortal and categorizes them into 7 families based on their structural features. For each family, it defines a unified abstraction network and quality assurance methodology. As an example, it applies the framework to the Cancer Chemoprevention Ontology, identifies errors, and shows how the ontology was improved. The framework aims to improve the scalability and efficiency of quality assurance for the large number of ontologies in BioPortal.
The document describes an algorithm called "Hide" that identifies and removes redundant import of classes from a top-level ontology into a domain ontology. It was developed to improve quality assurance of ontologies by removing unused imported classes. The algorithm is demonstrated by applying it to the Drug Discovery Investigations (DDI) ontology, where it identified and hid 18 out of 32 imported Basic Formal Ontology (BFO) classes that were not used in DDI. Future work is needed to handle more complex ontology structures and relationships between classes.
El documento resume la historia y evolución del mercadeo a través de varias etapas. Inicialmente, durante la etapa de autosuficiencia económica, los grupos familiares producían solo para su propio consumo. Luego, con la aparición de la división del trabajo, surgió la etapa del trueque, donde los excedentes de producción eran intercambiados entre grupos. Más adelante, la introducción de la moneda durante la etapa monetaria facilitó el comercio nacional e internacional. Finalmente, en las décadas
Este documento es el plan de vida de Aylin Rivera Coquet. Resume que actualmente es una estudiante y hija. Sus fortalezas incluyen su familia, caracter y determinacion, mientras que sus debilidades son la enfermedad, pruebas y cansancio. Su objetivo es graduarse de la universidad para tener una carrera profesional y eventualmente formar su propia familia.
This document describes a study that used structural matching of concept pairs from six reference terminologies and SNOMED CT in the UMLS to identify potential relationships for semantic harmonization. 241 concept pairs were reviewed. 59.3% represented alternative classifications, 23.6% potential parent-child relationships, and 14.5% new synonyms. Some errors were also identified. The study demonstrates that structural matching may complement expert review in identifying concepts for import/export between terminologies.
This document describes a study that identified questionable relationship triples in the Unified Medical Language System (UMLS) Metathesaurus. The researchers developed an algorithm to automatically identify suspicious relationship triples that fall into four cases: 1) conflicting hierarchical relationships, 2) redundant hierarchical relationships, 3) mixed hierarchical/lateral relationships, and 4) multiple mutually exclusive lateral relationships. Statistics on the identified questionable relationships in the UMLS 2010AA release are presented, along with a discussion of relationship issues that may arise from the integration of source vocabularies.
This document presents a method for using patterns in clinical trial data to recommend new conditions for drug retesting. The authors analyzed drug retesting patterns across trials on ClinicalTrials.gov and found drugs were often retested in conditions whose trials had similar eligibility criteria. They developed an approach leveraging shared eligibility criteria between conditions to recommend potential new retesting targets. As a proof of concept, they were able to validate one recommendation for ranolazine in myocardial infarction based on a published study. However, more sophisticated models are still needed to fully evaluate this method for drug repurposing.
1. The document describes a method to assess the population representativeness of clinical trials for type 2 diabetes (T2DM) by comparing patient data from national health surveys to eligibility criteria from T2DM trials.
2. Key characteristics like age, HbA1c, and BMI were extracted from trial summaries and compared to values for over 15,000 T2DM patients from NHANES surveys using visualization and generalizability index scores.
3. Preliminary results suggest trials may underrepresent older patients and those with lower HbA1c levels compared to real-world T2DM populations. This work aims to improve transparency around trial eligibility and population representativeness.
Midwest Pantry, based in Minneapolis, has created unique events to help grow companies that make & sell local food in America’s Heartland.
This slideshare will give you an overview of the Local Food & Gift Tradeshow, Top of the Pantry (TOPS) Awards, Local Food Poster Show, Shop Small Holiday Market, and our Education Series.
We'd love to hear from you if you'd like to participate in any of our events, or would like more information about becoming a strategic partner.
Este documento es el plan de vida de Aylin Rivera Coquet. Resume que actualmente es una estudiante y hija. Sus fortalezas incluyen su familia, caracter y determinacion, mientras que sus debilidades son la enfermedad, pruebas y cansancio. Su objetivo es graduarse de la universidad para tener una carrera profesional y eventualmente formar su propia familia.
This document describes a study that used structural matching of concept pairs from six reference terminologies and SNOMED CT in the UMLS to identify potential relationships for semantic harmonization. 241 concept pairs were reviewed. 59.3% represented alternative classifications, 23.6% potential parent-child relationships, and 14.5% new synonyms. Some errors were also identified. The study demonstrates that structural matching may complement expert review in identifying concepts for import/export between terminologies.
This document describes a study that identified questionable relationship triples in the Unified Medical Language System (UMLS) Metathesaurus. The researchers developed an algorithm to automatically identify suspicious relationship triples that fall into four cases: 1) conflicting hierarchical relationships, 2) redundant hierarchical relationships, 3) mixed hierarchical/lateral relationships, and 4) multiple mutually exclusive lateral relationships. Statistics on the identified questionable relationships in the UMLS 2010AA release are presented, along with a discussion of relationship issues that may arise from the integration of source vocabularies.
This document presents a method for using patterns in clinical trial data to recommend new conditions for drug retesting. The authors analyzed drug retesting patterns across trials on ClinicalTrials.gov and found drugs were often retested in conditions whose trials had similar eligibility criteria. They developed an approach leveraging shared eligibility criteria between conditions to recommend potential new retesting targets. As a proof of concept, they were able to validate one recommendation for ranolazine in myocardial infarction based on a published study. However, more sophisticated models are still needed to fully evaluate this method for drug repurposing.
1. The document describes a method to assess the population representativeness of clinical trials for type 2 diabetes (T2DM) by comparing patient data from national health surveys to eligibility criteria from T2DM trials.
2. Key characteristics like age, HbA1c, and BMI were extracted from trial summaries and compared to values for over 15,000 T2DM patients from NHANES surveys using visualization and generalizability index scores.
3. Preliminary results suggest trials may underrepresent older patients and those with lower HbA1c levels compared to real-world T2DM populations. This work aims to improve transparency around trial eligibility and population representativeness.
Midwest Pantry, based in Minneapolis, has created unique events to help grow companies that make & sell local food in America’s Heartland.
This slideshare will give you an overview of the Local Food & Gift Tradeshow, Top of the Pantry (TOPS) Awards, Local Food Poster Show, Shop Small Holiday Market, and our Education Series.
We'd love to hear from you if you'd like to participate in any of our events, or would like more information about becoming a strategic partner.
2. ΤΙ ΕIΝΑΙ ΠΙΣΤΩΤΙΚΗ ΚΑΡΤΑ
Είναι ένα είδος πίστωσης, όπου ο κάτοχος της στην ουσία
δανείζεται χρήματα, αλλά σε πλαστική μορφή, και έχει τη
δυνατότητα να αγοράσει αγαθά και υπηρεσίες χωρίς την άμεση
καταβολή της αξίας τους.
2
3. ΙΣΤΟΡΙΚΗ ΑΝΑΔΡΟΜΗ ΤΗΣ
ΠΙΣΤΩΤΙΚΗΣ ΚΑΡΤΑΣ
Ξεκίνησα σαν ιδέα στην Αμερική, όταν διάφορες επιχειρήσεις
προσέφεραν στους καλούς πελάτες τους τη δυνατότητα αγορών με
πίστωση
1946 -> Flatbush National Bank of Brooklyn
1950 -> κάρτα Diners από τον Frank McNamara
1958 -> American Express (Bankamericard, μετέπειτα Visa)
3
4. ΠΑΡΟΧΕΣ ΠΙΣΤΩΤΙΚΗΣ ΚΑΡΤΑΣ
• Δυνατότητα αγοράς υπηρεσιών/αγαθών χωρίς την άμεσα
καταβολή του ποσού της αξίας τους
• Συναλλαγές μέσω ίντερνετ
• Παροχή δωρεάν βραχυπρόθεσμης πίστωσης
• Προστασία αγορών
• Ασφάλεια από την κλοπή στη μεταφορά χρημάτων
• Υπερανάληψη μετρητών μέχρι του πιστωτικού ορίου της
κάρτας
• Δυνατότητα παροχής πρόσθετων υπηρεσιών* (π.χ. ιατρική και
4
5. ΠΑΡΟΧΕΣ ΠΙΣΤΩΤΙΚΗΣ ΚΑΡΤΑΣ
(συνέχεια)
• Παρακολούθηση μηνιαίων εξόδων για όλες τις αγορές που
πραγματοποιήθηκαν
• Δυνατότητα αγοράς με δόσεις σε πολύ χαμηλό έως και μηδενικό
επιτόκιο*
• Δυνατότητα αγοράς από όλο τον κόσμο (σε περίπτωση
ταξιδιού)
5
6. 6
ΕΙΔΗ ΠΙΣΤΩΤΙΚΩΝ ΚΑΡΤΩΝ
-Κάρτα αυτόματων συναλλαγών. Καθένας έχει λογαριασμό
καταθέσεων στην εκδότρια τράπεζα, μπορεί να διενεργεί
μέσω ΑΤΜ.
- Χρεωστική κάρτα. Εκδίδεται συνήθως όταν έχουμε ήδη
τραπεζικό λογαριασμό καταθέσεως.
- Έξυπνη κάρτα. Αντί για μαγνητική ταινία στην οποία είναι
καταγεγραμμένα τα στοιχεία του χρήστη, υπάρχει ένα μικροτσίπ
στο οποίο είναι αποθηκευμένα διάφορα δεδομένα και
πληροφορίες.
7. 7
ΕΙΔΗ ΠΙΣΤΩΤΙΚΩΝ ΚΑΡΤΩΝ
(συνέχεια)
-Κάρτα εγγύησης επιταγών (Scheckkarte). Εκδίδεται από
τράπεζες και παραδίδεται στον πελάτη-κάτοχο μαζί με ένα
μπλοκ ειδικών αριθμημένων επιταγών.H τράπεζα
εγγυάται να πληρώσει μέχρι ένα ορισμένο ποσό το
οποίο καθορίζεται στη σύμβαση μεταξύ της τράπεζας και
του κατόχου.
8. 8
ΠΟΙΑ ΕΙΝΑΙ Η ΚΑΛΥΤΕΡΗ
ΠΙΣΤΩΤΙΚΗ ΚΑΡΤΑ ΓΙΑ ΕΜΕΝΑ
Προτάσεις για την επιλογή της πιο συμφέρουσας πιστωτικής
κάρτας:
Εάν εξοφλείται εμπρόθεσμα το σύνολο του μηνιαίου
οφειλόμενου υπολοίπου
Εάν δεν εξοφλείται μηνιαίως το σύνολο των μηνιαίων
οφειλομένων υπολοίπων
Εάν θέλετε να απαλλαγείτε από το συσσωρευμένο
υπόλοιπο
Συχνή χρήση στο εξωτερικό
Ανάληψη μετρητών
9. 9
ΟΙ ΚΙΝΔΥΝΟΙ ΑΠΟ ΤΗΝ ΠΛΗΡΩΜΗ ΜΕ
ΠΙΣΤΩΤΙΚΗ ΚΑΡΤΑ ΜΕΣΩ
ΔΙΑΔΙΚΤΥΟΥ Έλλειψη ασφάλειας κατά τις συναλλαγές.
- Ακόμα και ο προμηθευτής μπορεί να κάνει ανάληψη
ποσού μεγαλύτερου του συμφωνημένου
- Δεν είναι απαραίτητη η διεύρυνση των στοιχείων του
κατόχου
- Υπάρχουν σελίδες που για να γίνεις δωρεάν μέλος
χρειάζεται αριθμό πιστωτικής κάρτας
Προγράμματα που επικολλούνται στα αρχεία που κατεβάζει
ο χρήστης και εγκαθιστά στον Η/Υ του.
- Καταγράφουν τα πλήκτρα που πατά ο χρήστης
- Τέτοιες απάτες μπορούν να γίνουν μέσω spy ware,
με δούρειους ίππους
10. 10
ΟΙ ΚΙΝΔΥΝΟΙ ΑΠΟ ΤΗΝ ΠΛΗΡΩΜΗ ΜΕ
ΠΙΣΤΩΤΙΚΗ ΚΑΡΤΑ ΜΕΣΩ
ΔΙΑΔΙΚΤΥΟΥ (συνέχεια)
Phishing.
- Μήνυμα ηλεκτρονικού ταχυδρομείου από επιτήδειους
προς τον κάτοχο της πιστωτικής κάρτας
- Φαίνεται να είναι σταλμένο από εκδότη της
πιστωτικής κάρτας
- Ζητούνται στοιχεία νόμιμου κατόχου
Φαινόμενο Scam.
- Αποστέλεται ένα ηλεκτρονικό μήνυμα προτρέποντας
επαγγελματική συνεργασία με αντικείμενο μια εύκολη δουλειά με
υψηλές αποδόσεις
-Απαιτείται κάποιο μικρό χρηματικό αντίτιμο για
την ενημέρωση μέσω της πιστωτικής κάρτας
11. 11
ΟΙ ΚΙΝΔΥΝΟΙ ΑΠΟ ΤΗΝ ΠΛΗΡΩΜΗ ΜΕ
ΠΙΣΤΩΤΙΚΗ ΚΑΡΤΑ ΜΕΣΩ
ΔΙΑΔΙΚΤΥΟΥ (συνέχεια)
Farming.
- Διαδικτυακή επίθεση που ανακατευθύνει την κίνηση
ενός ιστοτόπου σε μια ψεύτικη ιστοσελίδα
- Χάκερ κατευθύνονται μέσω της δηλητηρίασης DNS
και αποκτούν πρόσβαση στις βάσεις δεδομένων
- Υποκλέβουν όλα τα στοιχεία δρομολόγησης του
θύματος και μπορούν να χρεώσουν την πιστωτική του κάρτα
12. 12
ΣΤΟΙΧΕΙΑ ΓΙΑ ΤΙΣ ΑΠΑΤΕΣ
Η Visa το 2002 δήλωσε ότι πάνω από χίλιοι Έλληνες έπεσαν θύματα
απάτης σε σχέση με τις πιστωτικές τους κάρτες.