Smilebox can be used for personal, business, and educational contexts. Personally, it allows sharing photos with families and customizing presentations with music and designs. Businesses can use it for event invitations and recaps. Educationally, it teaches skills like scrapbooking and collaging through creating slideshows. The document provides instructions on making a Smilebox account and building a presentation by uploading photos, adding a design and music, and sharing the final product.