There is a lost pet crisis in the United States with millions of pets lost each year and not returned to their owners. Maximizing the use of microchipping can help increase the return of lost pets to their owners. To improve the effectiveness of microchipping, shelters should demand ISO microchips, register all implanted microchips and educate adopters, use universal scanners, and utilize tools like Petmicrochiplookup.org to check multiple registries and contact the appropriate one. These actions can boost return rates and live outcomes while reducing strain on shelters.