Schizophrenia is a serious mental illness that affects about 70 million people worldwide. It is characterized by distortions in thinking, perception, emotions, language, sense of self and behavior. Common symptoms include hallucinations, delusions, reduced social engagement and emotional expression. While the exact causes are unknown, genetic and environmental factors likely contribute. Treatment involves antipsychotic medications and psychosocial therapies. With proper treatment, many people with schizophrenia can lead productive lives.

1. "Schizophrenia"
What is Schizophrenia?

2. • About 70 million people in the world and 3.1 million people in the United States
have the mental illness schizophrenia.(MHA) Despite the fact that millions of
people suffer from schizophrenia and it was identified over 125 years ago as a
separate and distinct mental illness, it is perhaps the most misunderstood and
stigmatized mental illness of all.
• Some people have the misconception that schizophrenia is a split or multiple
personality disorder.
• Although the word schizophrenia derived from the Greek words schizo and
phrene which when translated literally mean split mind, this term was not used
to convey a noticed split personality. This word was instead given to describe the
often fragmented thinking noticed in people suffering with this type mental
illness.
• Many people still believe that a mentally ill person is likely to act out violently
towards other's. Although research does suggest an increase of risk for violent
behavior particularly in early occurrences ones schizophrenia. These acts of
violence occur from only a subset of people with the disorder and account for
only about 3 to 5% of the total violence in our society. However, how much ones
mental illness actually contributes to these noted acts of violence is unknown,
because other factors often exist such as substance abuse and violent
environments and these are also contributing factors.

3. • According to the National Alliance on Mental Illness (NAMI)
the greatest risk for violent acts to occur by a mentally ill
person is when that person also has a substance abuse
disorder. However substance abuse always increases the risk
of violence even among people without mental disorders.
There is also a small elevation of risk for increased violence if
a person is being non-compliant with their treatment.
• Despite some peoples perceptions, the vast majority of
people with schizophrenia that are receiving proper medical
treatment, and are abstaining from alcohol and drug abuse,
pose little to no more threat of violence towards other's than
anyone else does. The majority of people with schizophrenia
are not violent and are living relatively independent lives.
Most are in fact very productive contributing members to our
society.

4. • Schizophrenia is a serious mental illness that has an effect on
how a person feels, behaves, and thinks. It is a brain disorder
that interferes with and deteriorates how ones thoughts,
emotions, and behavior relate with each other. This
interference and deterioration effects a persons ability to
interpret reality. This loss of contact with reality causes
delusions (false beliefs) about ones identity and the hearing
and seeing of things that in reality are not there.
• Schizophrenia is not the same as schizoaffective disorder,
schizophasia, multiple personality disorder or schizoid
personality disorder. The onset of schizophrenia most typically
occurs in men between their teen years and mid twenties. In
women the onset usually occurs in their mid twenties to mid
thirties.

5. Random Schizophrenia Facts:
• On average, people with schizophrenia die earlier than the general population.
Men an average of 15 years earlier and women an average of 12 years earlier.
• A person with schizophrenia is twice as likely as the general population to
become diabetic or suffer from chronic obstructive pulmonary disease.(COPD)
• The risk for dying from conditions such as diabetes, COPD, cancer, stroke, and
cardiovascular disease are increased for those with schizophrenia.
• People with schizophrenia are more a threat to themselves than others.
• Statistics show that 40-60% of people with schizophrenia attempt suicide.
• Statistics show that historically between 10 and 15% of people with
schizophrenia commit suicide.
• Antipsychotic medications used for treating schizophrenia do not produce a
“high” or addictive behavior.
• People with schizophrenia often make the common mistake of trying to ignore
the illness as if it does not exist.
• There are five different types of schizophrenia; residual, catatonic, disorganized,
paranoid, and undifferentiated.
• People with mental illness are more likely to be diagnosed with a substance use
disorder than people without mental illness.
• The signs and symptoms of schizophrenia vary from individual to individual.

6. Schizophrenia Symptoms:
• The signs of schizophrenia are different for everyone. Some
may experience only one or two symptoms while others may
experience many. Symptoms may develop slowly over months
or years, or may appear very abruptly. In some people their
detachment from reality is a constant part of their life, while
in others their symptoms will come and go in cycles of relapse
and remission.
• People with schizophrenia do not always act abnormally. They
may appear perfectly responsible and in control, even when
experiencing some of their symptoms. Schizophrenia
symptoms are usually put into three categories: Positive
symptoms, negative symptoms, and disorganized symptoms.

7. Positive schizophrenia
symptoms
• Positive schizophrenia symptoms are the obvious psychotic
abnormal symptoms that appear in a person with schizophrenia that
do not appear in a healthy person. They are things added to ones
personality or behavior patterns that should not be there. They
include:
• Delusions: individuals may believe that someone is spying on him or
her, or that they are someone famous.
• Movement disorder: strange mannerisms, pacing, posturing, or
rocking back and forth with no purpose.
• Thought disorder: moving from one topic to another, in a
nonsensical fashion. Individuals may make up their own words or
sounds.
• Hallucination: seeing, feeling, tasting, hearing or smelling something
that doesn't really exist. The most common experience is hearing
imaginary voices that give commands or comments to the
individual.

8. Negative schizophrenia
symptoms
• Negative schizophrenia symptoms reflects the absence of
certain normal behaviors in people with schizophrenia. They
include:
• Lack of emotion
• Abnormal emotion expression such as crying at a joke when a
normal response would be to laugh.
• Social withdrawal from family and friends
• Problems successfully functioning in the normal activities of
life such as at work or school.
• Poor hygiene
• Catatonia
• Loss of interest in life

9. Disorganized symptoms of
schizophrenia
• Disorganized symptoms of schizophrenia effect ones ability to
think things through clearly so as to respond appropriately to
them. They include:
• Talking in sentences that do not make sense.
• Problems making decisions.
• Forgetting or losing things.
• Problems making sense of everyday sights, sounds, and
feelings.
• Shifting quickly from one thought to the next.
• Pacing and walking in circles.
• Excessive writing but without meaning.

10. • The symptoms suffered by a person with schizophrenia can be very
debilitating. Schizophrenia can have severe negative effects on ones
everyday life. These symptoms can effect a persons relationships,
employment, finances, schooling, and overall enjoyment of life. One
can only try and imagine how fearful and terrifying it must be to
hear voices, believe that others are plotting to harm you or are
trying to control your mind. Hallucinations and delusional thinking
are severe symptoms very commonly experienced by those who
suffer from schizophrenia. Some commonly expressed hallucinations
and delusions by people with schizophrenia, include:
• The government was watching me with planted video cameras.
• I at times thought that aliens were communicating with me through
street lights.
• I heard voices and could not sleep at night.
• The voice told me to kill myself in a slow painful way.
• My thoughts seemed to broadcast through the radio.
• I began feeling more and more that everyone was trying to get me.
• I thought that maybe I was the Jesus of old.

11. What Causes Schizophrenia?
• Despite much research scientists still have not pinpointed the
precise cause of schizophrenia. However research has led
some scientist to believe that people with schizophrenia are
born with a predisposition for developing the illness, which
they acquired during the early development of their brains.
• This predisposition in the brain when accompanied by various
other factors then triggers the onset of schizophrenia. The
most common factors and triggers responsible for the
development of schizophrenia, include:

12. • Brain chemical imbalance: The brains of people with schizophrenia
have abnormal production or reaction to the important chemical
neurotransmitter dopamine and maybe others. Dopamine is
responsible in sending messages through the brain and effects how
the brain perceives things.
• Environmental Factors: Stress inducing environmental factors such
as social pressure, physical or sexual abuse, loss of loved ones,
hormones, malnutrition, and early exposure to viruses. The major
brain changes that occur during puberty has also been identified as
a possible contributing factor. Stressors can have profound effects
on the amount of activity that's going on in the inflammatory
immune system and the immune system impacts brain function.
Evidence suggests that inflammation plays a role in the origin of
schizophrenia. (NCBI)
• Hereditary factor: People who have a family history of schizophrenia
have a higher probability for developing it. If ones mother, father,
brother or sister has the illness, statistics show a 10 percent chance
of developing it. If ones twin, or both father and mother has the
disorder then the probability of developing it rises to 40 percent.
Whereas the general population only has an overall 1 percent risk of
developing schizophrenia.

13. Schizophrenia Treatment:
• Anyone can get schizophrenia. People throughout the world of all races, cultures,
backgrounds, and socioeconomic groups are diagnosed with schizophrenia. Treatment
results reported by The National Alliance on Mental Illness (NAMI) is encouraging. It is
reported that with treatment about 80 percent of people with schizophrenia are able
to lead productive and relatively independent lives. In 50 percent of the cases
recovery is significant or even complete. About 20% of sufferers will experience
relapse and will require a longer-term more structured treatment program.
• So recovery is achievable in half of all cases for people who seek treatment for their
schizophrenia. Recovery is defined by NAMI as not showing any symptoms and living
in the community engaging in positive social interactions with their family and friends.
In situations where a full recovery is not achieved, treatment often greatly reduces
the severity of symptoms and still improves one's quality of life. Treatment for
schizophrenia may include:
• Drug Therapy: Antipsychotic medication is often very successful in treating
schizophrenia. Antipsychotics have an affect on the brains dopamine and serotonin
neurotransmitters which helps to normalize the chemical imbalance and relieve the
most troubling schizophrenia symptoms. Schizophrenia appears to include not only a
thought disorder but also anxiety and mood disorder. For this reason antidepressants
and short term use of antianxiety medications are sometimes included in the
treatment plan. The most commonly prescribed drugs for treating schizophrenia,
include:

14. • Conventional
antipsychotics:
• Chlorpromazine
(Thorazine)
• Fluphenazine (Prolixin)
• Haloperidol (Haldol)
• Thiothixene (Navane)
• Trifluoperazine
(Stelazine)
• perphenazine (Trilafon)
• Thioridazine (Mellaril)
• Newer atypical
antipsychotics:
• Aripiprazole (Abilify)
• Clozapine (Clozaril)
• Ziprasidone (Geodon)
• Quetiapine Fumarate
(Seroquel)
• Olanzapine (Zyprexa)
• Risperidone (Risperdal)
• Paliperidone (Invega)
• Asenapine (Saphris)

15. Antidepressants:Thetwomostcommonlyused
antidepressanttypesareSSRI'sandSNRI's
Selective serotonin reuptake
inhibitors (SSRI)
• Sertraline (Zoloft)
• Escitalopram (Lexapro)
• Fluoxetine (Prozac)
• Citalopram (Celexa)
• Paroxetine (Paxil)
Serotonin and norepinephrine
reuptake inhibitors (SNRI)
• Duloxetine (Cymbalta)
• venlafaxine (Effexor)

16. Antianxiety Medications:
• Alprazolam (Xanax)
• Clonazepam (Klonopin)
• Diazepam (Valium)
• Lorazepam ( Ativan)
• All of the medications mentioned on these slides and these
medications above have there own levels of side effects and
risks. Researchers are working to better understand these side
effects so as to lessen the risk and manage the complications
associated with them. It is very important to take these
medications only under a doctors orders and in the dosage
and frequency amount specified by ones doctor. One should
also investigate and discuss with their doctor's all possible side
effects, their severity, and risk levels, as it is their health and
quality of life that is in question.

17. Psychosocial therapy
• While medication can help relieve the symptoms associated with
schizophrenia, psychosocial therapy can help one deal with other
important issues. Issues often associated with the illness, such as
occupation, self-care, relationships, motivation, and communication
can be addressed.
• Through psychosocial therapy patients can learn coping
mechanisms, how to manage their symptoms, how to identify early
warning signs of relapse, how to respond to them, and how to
prevent relapses. They are thus less likely to relapse or have need
for hospitalization. Those who receive psychosocial therapy who are
also on a drug treatment regime are more likely to adhere to it.
Psychosocial therapies include:
• Individual psychotherapy
• Family therapy
• Group therapy/support groups

18. • Rehabilitation: Can help a person with schizophrenia to reach
their greatest functioning level and thus live as independently
as possible. Rehabilitation program staff members can help
one to find work, housing, and helpful social activities.
• Support Groups: These can be very helpful for those with
schizophrenia and for their family members and friends. There
are local support groups and there are also helpful online
support groups, such as:
• NAMI Care Group NAMI Family Support NAMI Peer to Peer
Online Support Group
• Hospitalization: Most people with schizophrenia can be
treated without need for hospitalization. However, for those
with particularly severe symptoms, or those that are a danger
of hurting themselves or others, hospitalization may be
necessary to stabilize them.

19. • Electroconvulsive Therapy (ECT): Controlled electric current is
applied to the head while the patient is under anesthesia in
order to induce gran mile seizure. This procedure can be
effective but is most often used for patients that are non-
responsive to drug therapy. Severe long term memory loss has
been experienced in some patients after the procedure and is
the major risk that is reported for ECT.
• Vagus Nerve Stimulation (VNS): This is a treatment that
involves using electrical impulses to stimulate the vagus nerve
to send electrical signals to the brain-stem. The brain-stem
then sends signals to other areas of the brain. This procedure
requires the surgical placement of a stimulation device under
the skin. Their are some usually tolerable post surgical risks for
this procedure, such as headaches, nausea, chest pain and
hoarseness. There have also been some reports of surgical
complications similar to those found in other minor surgeries,
but these are rare.

20. Mental Health Supplements:
• Various herbs and dietary supplements have been used with some success in relieving
schizophrenia symptoms. Mental health supplements are usually considered most
successful when taken as supplemental treatments. Any consideration of adding a mental
health supplement to a persons course of treatment should be discussed with their doctor
before making any final decisions. Some of the most common mental health supplements
used for schizophrenia symptoms, include:
• Gamma-aminobutyric acid (GABA):
• 5-HTP:
• Glutathione
• Ginkgo
• Passionflower
• Flaxseed oil
• Folic acid
• Kava kava
• L-glutamic acid
• Glycine
• *The above mental health supplements have been used for improving mood and relieving
anxiety. Before taking such supplements one should always check with their doctor for any
known side effects or potential harmful interactions that could occur with other
medications they may be taking.

21. • There are various treatment methods available to help improve the lives
of those who suffer from schizophrenia. Researchers are continuing to
work to fully understand its cause so as to uncover any potential
preventive care or early discovery methods, so as to find even better
ways to prevent or treat it.
• In the U.S. drug therapy is the most common first line treatment
method for a patient experiencing a psychotic episode. If the response
to drug therapy is favorable, and the patient has remained symptom
free over a period of time, usually at least six months, an attempt may
be made to gradually withdraw the drug from the patient. (Harvard
Health) To further increase ones chances of full recovery, the patients
and their families by means of psychotherapy can learn the early signs
of relapse, how to respond to it, and how to prevent it.
• The form of psychotherapy known as cognitive behavior therapy (CBT)
when combined with drug therapy has shown to work well in treating
schizophrenia. However, there have also been some studies reported
that seem to support CBT as a viable and effective treatment of
schizophrenia without the use of any medication. One of those studies
results is reported in the Cambridge Journals Abstract.

22. • This study was small in scale as to participants (20), and
included only participants that had for at least six months
prior either discontinued or refused the use of medication as
treatment. This studies reported conclusion seems
encouraging. The study reported that all participants had
achieved reductions in social impairment, delusions, and
hallucinations. And that fifty percent of participants
experienced significant reductions in these symptoms.
• This study certainly seems to provide evidence that CBT
should be at least considered a viable treatment method for
people who refuse medication. As for using CBT treatment
independent of drugs as a primary and viable treatment
method in place of drug therapy, further more randomized,
larger scale, controlled trials seem in order.

23. Early Treatment Helps:
• If you or someone you know are experiencing the noted symptoms of
schizophrenia go see a medical professional right away. How soon the
treatment process begins after the onset of the illness can be a factor in
the overall treatment outcome.
• Early treatment with antipsychotic drugs is associated with significant
symptom reduction. Treatment can lead to a full recovery or at least
help limit the severity of your symptoms, and help improve the quality
of your life. If you don't seek help most likely your condition will worsen.
• Healing from schizophrenia is a process that takes patience. The chances
of treatment helping you are far greater than it not. But it is important
to recognize that it can sometimes take time for the treatment to attain
its full positive effects. There is no one set treatment that works for
everyone, treatment must be tailored for each specific individual.
• For example, with drug therapy treatment the type of medication(s)
used, the combination of drugs used, and the dosage amounts, often
have to be adjusted. Be patient and allow sufficient time for doctors to
find the treatment that best works for you.